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The map label for this gene is ppaX [H]

Identifier: 37519823

GI number: 37519823

Start: 261711

End: 262379

Strand: Reverse

Name: ppaX [H]

Synonym: gll0254

Alternate gene names: 37519823

Gene position: 262379-261711 (Counterclockwise)

Preceding gene: 37519825

Following gene: 37519822

Centisome position: 5.63

GC content: 66.67

Gene sequence:

>669_bases
ATGTCCGAACGGTTGGTCGTCTTCGATCTCGACGGTACGCTCATCGATTCGGAAGGGGGAATTGTGCTTGCCATGGAGCG
TACGGCCCTGGCCCTGGCCCTGCCTGGGGGCACCGTCGAGCGCTGGCGCAAGCTCATCGGCATGCCCCTACGCGAGCAAA
TGCCTGCGATTTTGCCCGCGGAGCGCCTCGCGGAAGCCCCCCGGGTGGTGGAGTGCTACCGCGAGGTTTACCGCGAAATC
ATGCTGCCCATGAGCCGCCCCTTCGCCGGCACCGACGCCCTGGTGCGCGCCTTGCACCGCCGCGGGGTAATGCTGGCCAT
CTGCTCGGGCAAGCGCGGCCGCTCGATTCGGGAGGTGCTCGCTCAGGCGGGATGGCTCGAATTTTTTGAAACGATCGTCT
CCCCGGACGAAGTGATTCGGGGTAAGCCCGACCCCGAATCGCTCAAGCTCGCCCTTGCCCTCACCGGCTTCGGGGTGGGC
GAAGCGCTGATGGTGGGCGACACCACCCTCGATATCGAAATGGCCCGCGCCGCCGGGGTGGCCTGCTGTGCGGTCACCTG
GGGCACCCACGGGCGCGAGGAGTTGGTCTCTGCTCGGCCGGATTTTTGGGTCGAGACGGTTGAAGAACTGGCCGGGCGCC
TCGACCGTTGGCTGGGCTGGAGCGCTTGA

Upstream 100 bases:

>100_bases
AGATTCATGGGAACCGATGGTGAGGAGTATTGGAAAAGAGTCTAGGTGAGAAGCACCGGTAAAGGCTATAAATCTGGGTT
GGCCTTTGCAGGAGCGCCGG

Downstream 100 bases:

>100_bases
GGTTGCCCGGACAACGGCCAGTTGGATGGAACCTCAATGGGCAACGGTTGCATTTCTGACACCTGGCGGTTGGCTTTGCA
CGACAGTCTGTGGAGCGAGA

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MSERLVVFDLDGTLIDSEGGIVLAMERTALALALPGGTVERWRKLIGMPLREQMPAILPAERLAEAPRVVECYREVYREI
MLPMSRPFAGTDALVRALHRRGVMLAICSGKRGRSIREVLAQAGWLEFFETIVSPDEVIRGKPDPESLKLALALTGFGVG
EALMVGDTTLDIEMARAAGVACCAVTWGTHGREELVSARPDFWVETVEELAGRLDRWLGWSA

Sequences:

>Translated_222_residues
MSERLVVFDLDGTLIDSEGGIVLAMERTALALALPGGTVERWRKLIGMPLREQMPAILPAERLAEAPRVVECYREVYREI
MLPMSRPFAGTDALVRALHRRGVMLAICSGKRGRSIREVLAQAGWLEFFETIVSPDEVIRGKPDPESLKLALALTGFGVG
EALMVGDTTLDIEMARAAGVACCAVTWGTHGREELVSARPDFWVETVEELAGRLDRWLGWSA
>Mature_221_residues
SERLVVFDLDGTLIDSEGGIVLAMERTALALALPGGTVERWRKLIGMPLREQMPAILPAERLAEAPRVVECYREVYREIM
LPMSRPFAGTDALVRALHRRGVMLAICSGKRGRSIREVLAQAGWLEFFETIVSPDEVIRGKPDPESLKLALALTGFGVGE
ALMVGDTTLDIEMARAAGVACCAVTWGTHGREELVSARPDFWVETVEELAGRLDRWLGWSA

Specific function: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. PpaX family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=234, Percent_Identity=26.9230769230769, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 24419; Mature: 24288

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERLVVFDLDGTLIDSEGGIVLAMERTALALALPGGTVERWRKLIGMPLREQMPAILPA
CCCCEEEEECCCEEEECCCCEEEEEECCEEEEECCCCCHHHHHHHHCCCHHHHCCCCCCH
ERLAEAPRVVECYREVYREIMLPMSRPFAGTDALVRALHRRGVMLAICSGKRGRSIREVL
HHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHH
AQAGWLEFFETIVSPDEVIRGKPDPESLKLALALTGFGVGEALMVGDTTLDIEMARAAGV
HHHHHHHHHHHHCCHHHHHCCCCCHHHEEEEEEEECCCCCCEEEECCCEEHHHHHHHCCE
ACCAVTWGTHGREELVSARPDFWVETVEELAGRLDRWLGWSA
EEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SERLVVFDLDGTLIDSEGGIVLAMERTALALALPGGTVERWRKLIGMPLREQMPAILPA
CCCEEEEECCCEEEECCCCEEEEEECCEEEEECCCCCHHHHHHHHCCCHHHHCCCCCCH
ERLAEAPRVVECYREVYREIMLPMSRPFAGTDALVRALHRRGVMLAICSGKRGRSIREVL
HHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHH
AQAGWLEFFETIVSPDEVIRGKPDPESLKLALALTGFGVGEALMVGDTTLDIEMARAAGV
HHHHHHHHHHHHCCHHHHHCCCCCHHHEEEEEEEECCCCCCEEEECCCEEHHHHHHHCCE
ACCAVTWGTHGREELVSARPDFWVETVEELAGRLDRWLGWSA
EEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA