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The map label for this gene is rpiA

Identifier: 37519599

GI number: 37519599

Start: 29214

End: 29906

Strand: Reverse

Name: rpiA

Synonym: gvip001

Alternate gene names: 37519599

Gene position: 29906-29214 (Counterclockwise)

Preceding gene: 37519600

Following gene: 37519596

Centisome position: 0.64

GC content: 65.51

Gene sequence:

>693_bases
GTGGACCTCGATATCCTCAAGCAAACGGCGGCTCGGCGCGCTGTCGAGCTTGTCGAAGATGGCATGGTGGTCGGGCTGGG
CACCGGCTCGACCGCCGCATTTGCAGTGAGCGTCCTCGCCGAGCGAGTGCGCCTGGGGCTGCGGGTGGTGGGGATCCCCA
CCTCGGAGCGCACCGCCCGCCAAGCTGAGGCGGAGGGTATTGTTCTGGGGACACTGGCGGAGCAATCCAGGGTCGATCTC
ACCATCGATGGGGCGGACGAGGTGGCCCTGGGGGAGCTGGCCCTTATCAAGGGCCTGGGTGGTGCTTTGTTGCGCGAAAA
GATTGTCGCTGCCGCGAGCGAGAGGCTGATTATCATCGTCGATGCCACCAAGCTCGTCGAACAGCTTGGTAGCCACGGCC
CGCTGCCGGTGGAGGTGGCGCCGTTTGGCTGGCAGGCGACCGCCCGCGCCCTGGAGCGGCTCGGTGCCGAGGTGAATCTG
CGAGCCCAGCATGGACAAGCGTTTCTCACCGACGGCGGCCACTACATCCTTGATTGTCGTTTTGGACCGATCGCCCGGCC
GGCCGAACTCGAAGCGGCCATCGACCGTATCCCGGGGGTGGTGGAAAGCGGTCTGTTTGTCGGCATGGCAAGCGCGGTGA
TCGTAGCCGACGAGGGGGGTATCGAAGTGCTCACACCTTCTGCAGCGCCTTGA

Upstream 100 bases:

>100_bases
ATTGCCAAGATCTTGGGCGTAAGCGGTTTGCCCGCCATGATGATTGTCGCCATCATCGTTCCCAACGGCCCTTTCTAGCG
CATCGAAGCCAGACTGAGCG

Downstream 100 bases:

>100_bases
GCACCGCGAGTACCTCGTCGGTCGAGGCGTTGCTGTCGATAAACGAGAACAGGTGCCGATAGACGATCGTGCCGGTCATA
TCGACGATGTATTGGGCCGG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MDLDILKQTAARRAVELVEDGMVVGLGTGSTAAFAVSVLAERVRLGLRVVGIPTSERTARQAEAEGIVLGTLAEQSRVDL
TIDGADEVALGELALIKGLGGALLREKIVAAASERLIIIVDATKLVEQLGSHGPLPVEVAPFGWQATARALERLGAEVNL
RAQHGQAFLTDGGHYILDCRFGPIARPAELEAAIDRIPGVVESGLFVGMASAVIVADEGGIEVLTPSAAP

Sequences:

>Translated_230_residues
MDLDILKQTAARRAVELVEDGMVVGLGTGSTAAFAVSVLAERVRLGLRVVGIPTSERTARQAEAEGIVLGTLAEQSRVDL
TIDGADEVALGELALIKGLGGALLREKIVAAASERLIIIVDATKLVEQLGSHGPLPVEVAPFGWQATARALERLGAEVNL
RAQHGQAFLTDGGHYILDCRFGPIARPAELEAAIDRIPGVVESGLFVGMASAVIVADEGGIEVLTPSAAP
>Mature_230_residues
MDLDILKQTAARRAVELVEDGMVVGLGTGSTAAFAVSVLAERVRLGLRVVGIPTSERTARQAEAEGIVLGTLAEQSRVDL
TIDGADEVALGELALIKGLGGALLREKIVAAASERLIIIVDATKLVEQLGSHGPLPVEVAPFGWQATARALERLGAEVNL
RAQHGQAFLTDGGHYILDCRFGPIARPAELEAAIDRIPGVVESGLFVGMASAVIVADEGGIEVLTPSAAP

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=221, Percent_Identity=41.1764705882353, Blast_Score=140, Evalue=1e-33,
Organism=Escherichia coli, GI1789280, Length=207, Percent_Identity=40.0966183574879, Blast_Score=126, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17551758, Length=227, Percent_Identity=33.0396475770925, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324669, Length=236, Percent_Identity=31.7796610169492, Blast_Score=103, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281364072, Length=207, Percent_Identity=37.6811594202899, Blast_Score=113, Evalue=9e-26,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_GLOVI (Q7NPM5)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_922976.1
- ProteinModelPortal:   Q7NPM5
- SMR:   Q7NPM5
- GeneID:   2598422
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.30
- HOGENOM:   HBG515603
- OMA:   MVVIADA
- ProtClustDB:   PRK00702
- BioCyc:   GVIO251221:GLL0030-MONOMER
- BRENDA:   5.3.1.6
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23869; Mature: 23869

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLDILKQTAARRAVELVEDGMVVGLGTGSTAAFAVSVLAERVRLGLRVVGIPTSERTAR
CCHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCHHHHH
QAEAEGIVLGTLAEQSRVDLTIDGADEVALGELALIKGLGGALLREKIVAAASERLIIIV
HHHCCCEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEE
DATKLVEQLGSHGPLPVEVAPFGWQATARALERLGAEVNLRAQHGQAFLTDGGHYILDCR
EHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHCCCCEEEEECCCEEEEECCCEEEEEEC
FGPIARPAELEAAIDRIPGVVESGLFVGMASAVIVADEGGIEVLTPSAAP
CCCCCCCHHHHHHHHHCCCHHHCCHHEEEEEEEEEECCCCEEEECCCCCC
>Mature Secondary Structure
MDLDILKQTAARRAVELVEDGMVVGLGTGSTAAFAVSVLAERVRLGLRVVGIPTSERTAR
CCHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCHHHHH
QAEAEGIVLGTLAEQSRVDLTIDGADEVALGELALIKGLGGALLREKIVAAASERLIIIV
HHHCCCEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEE
DATKLVEQLGSHGPLPVEVAPFGWQATARALERLGAEVNLRAQHGQAFLTDGGHYILDCR
EHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHCCCCEEEEECCCEEEEECCCEEEEEEC
FGPIARPAELEAAIDRIPGVVESGLFVGMASAVIVADEGGIEVLTPSAAP
CCCCCCCHHHHHHHHHCCCHHHCCHHEEEEEEEEEECCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292