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The map label for this gene is marC [H]

Identifier: 34499820

GI number: 34499820

Start: 4708719

End: 4709366

Strand: Direct

Name: marC [H]

Synonym: CV_4365

Alternate gene names: 34499820

Gene position: 4708719-4709366 (Clockwise)

Preceding gene: 34499817

Following gene: 34499821

Centisome position: 99.11

GC content: 66.36

Gene sequence:

>648_bases
ATGTTCAAAACCCTGTCGCTGCAATTCCTGTTCGGCGGTCTGCTCAGCCTGATCACCATCACCAATCCGCTGTCCAAGAT
TCCGCTGTTCATCACGCTGACCCGCGAAATGAGCGACTCGCACCGCGACTCACAAGCCCGCCGCGCCTGCGTGTTCGCAG
CCGCCATCATGGCGGTGAGCCTGCTGGCCGGCAACCTGATCATGGCCGCCTTCGGCATTTCCTACGGCGCGCTGCGCATC
GCCGGCGGCTTCGTGGTGGCGGTGCTGGGCTACCGCATGCTGTTCCTGTCGCAGGATCCGGGCCAGGCGCCCAGACAGTC
GGGCGAACGCGAGGACTACGCCTTCTTCCCGCTGGCGATGCCCGGCATCAGCGGTCCGGGCACCATCGCGGTGGTGATCG
GCATCTCCACCGAGATCGCGGAGCTCTCCACGCTGCCGGCCAAGGCGCTGGCCTTCGCGATGACCTTCGCCGCCATCGGC
CTGACCTGCGTCGGCATGTGGCTGACGCTGAAGTCGTCGCTGCTGATCTCGGAGCGGCTGGGCCGCGGCGGCCGCGAGGT
GATGACCCGGCTGATGGGCTTCTTGCTGATCTGCATCGGCGTGCAGTTCGTCGGCTCCGGCATCCGCACCTTCATGGCCG
GCTCTTGA

Upstream 100 bases:

>100_bases
CCACACCTCGCCATGCCGCCGGTCTAAAGCGCAGTCCCCGGCTACCCCGCCGCAACGTAAGCCTCTACAATCTGCGGGCT
AGATACCCGGCCTCAACACC

Downstream 100 bases:

>100_bases
GCGCCGCGCGCGCGAACCCCATTTCTGCCACAATGAACGGATAGTCCCGCTATCCGTTCCGCCATGCCCGCTCCCGCCCA
AGAACGTTCCGAACTGTTCC

Product: multiple drug resistance protein MarC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MFKTLSLQFLFGGLLSLITITNPLSKIPLFITLTREMSDSHRDSQARRACVFAAAIMAVSLLAGNLIMAAFGISYGALRI
AGGFVVAVLGYRMLFLSQDPGQAPRQSGEREDYAFFPLAMPGISGPGTIAVVIGISTEIAELSTLPAKALAFAMTFAAIG
LTCVGMWLTLKSSLLISERLGRGGREVMTRLMGFLLICIGVQFVGSGIRTFMAGS

Sequences:

>Translated_215_residues
MFKTLSLQFLFGGLLSLITITNPLSKIPLFITLTREMSDSHRDSQARRACVFAAAIMAVSLLAGNLIMAAFGISYGALRI
AGGFVVAVLGYRMLFLSQDPGQAPRQSGEREDYAFFPLAMPGISGPGTIAVVIGISTEIAELSTLPAKALAFAMTFAAIG
LTCVGMWLTLKSSLLISERLGRGGREVMTRLMGFLLICIGVQFVGSGIRTFMAGS
>Mature_215_residues
MFKTLSLQFLFGGLLSLITITNPLSKIPLFITLTREMSDSHRDSQARRACVFAAAIMAVSLLAGNLIMAAFGISYGALRI
AGGFVVAVLGYRMLFLSQDPGQAPRQSGEREDYAFFPLAMPGISGPGTIAVVIGISTEIAELSTLPAKALAFAMTFAAIG
LTCVGMWLTLKSSLLISERLGRGGREVMTRLMGFLLICIGVQFVGSGIRTFMAGS

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787809, Length=195, Percent_Identity=44.1025641025641, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1787494, Length=208, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789842, Length=200, Percent_Identity=28.5, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 22839; Mature: 22839

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKTLSLQFLFGGLLSLITITNPLSKIPLFITLTREMSDSHRDSQARRACVFAAAIMAVS
CCCCHHHHHHHHHHHHHHHHCCCHHHCCEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHH
LLAGNLIMAAFGISYGALRIAGGFVVAVLGYRMLFLSQDPGQAPRQSGEREDYAFFPLAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEEEEEEEC
PGISGPGTIAVVIGISTEIAELSTLPAKALAFAMTFAAIGLTCVGMWLTLKSSLLISERL
CCCCCCCEEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRGGREVMTRLMGFLLICIGVQFVGSGIRTFMAGS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFKTLSLQFLFGGLLSLITITNPLSKIPLFITLTREMSDSHRDSQARRACVFAAAIMAVS
CCCCHHHHHHHHHHHHHHHHCCCHHHCCEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHH
LLAGNLIMAAFGISYGALRIAGGFVVAVLGYRMLFLSQDPGQAPRQSGEREDYAFFPLAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEEEEEEEC
PGISGPGTIAVVIGISTEIAELSTLPAKALAFAMTFAAIGLTCVGMWLTLKSSLLISERL
CCCCCCCEEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRGGREVMTRLMGFLLICIGVQFVGSGIRTFMAGS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA