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The map label for this gene is resA [H]

Identifier: 34499712

GI number: 34499712

Start: 4590773

End: 4591258

Strand: Direct

Name: resA [H]

Synonym: CV_4257

Alternate gene names: 34499712

Gene position: 4590773-4591258 (Clockwise)

Preceding gene: 34499711

Following gene: 34499721

Centisome position: 96.63

GC content: 62.14

Gene sequence:

>486_bases
ATGAAGAAGGGTTTGATCATTGCGCTGGCGCTGCTGGTCGCGGCCGGCGCCGCCTACAAGCTGATGTTCTCCGGCAGCCC
GGCTCCCGAGGTCAAACTGACCTCGCTGACCGGCGCCGTCACCAGCACCTCGGCGCTGAAAGGCAAGGTGGTGCTGGTGA
ACTTCTGGGCCACCAGCTGTCCCGGCTGCGTCGAGGAAATGCCGGAGATCAAGAAGCTGCACCAGGAATACGGCGGCAAG
GGACTCAACGTGCTGGCGGTGGCGATGAGCTACGATCCGCCCAACTACGTGCAGAATTTCGTCGCCAAGAACCAGTTGCC
CTTCTTCGTCGCGCTGGACCCGCAAGGCGCCACGGCCAAGGCCTTCGGCGACATCCAGCTGGCGCCCACCACCTTCCTGA
TCGACAAGCAGGGCAACATCATCAAGCGCTACGTCGGGGTGATGAACTTCGCCGAAGTGCGCAAGCTGATCGAGCAGCAT
CTGTAA

Upstream 100 bases:

>100_bases
AGAACAAGGCGGTGGTGCTGGAAGGGCAATTGAAGGCCATGCTGGAACAGATGACCGCCTCTACGGTCTGAACCGGCGGC
AGACACGACAGGAAATCGAG

Downstream 100 bases:

>100_bases
TCCCCGGTAGGGCGGAAGCCCCCTTGGGGCGTTCCGCCGCCCGCCTAACCTAGCTACCTCGGCGGAACTCCCGGCTAAAA
GCCGGGATTCCGCCCTACGG

Product: thioredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MKKGLIIALALLVAAGAAYKLMFSGSPAPEVKLTSLTGAVTSTSALKGKVVLVNFWATSCPGCVEEMPEIKKLHQEYGGK
GLNVLAVAMSYDPPNYVQNFVAKNQLPFFVALDPQGATAKAFGDIQLAPTTFLIDKQGNIIKRYVGVMNFAEVRKLIEQH
L

Sequences:

>Translated_161_residues
MKKGLIIALALLVAAGAAYKLMFSGSPAPEVKLTSLTGAVTSTSALKGKVVLVNFWATSCPGCVEEMPEIKKLHQEYGGK
GLNVLAVAMSYDPPNYVQNFVAKNQLPFFVALDPQGATAKAFGDIQLAPTTFLIDKQGNIIKRYVGVMNFAEVRKLIEQH
L
>Mature_161_residues
MKKGLIIALALLVAAGAAYKLMFSGSPAPEVKLTSLTGAVTSTSALKGKVVLVNFWATSCPGCVEEMPEIKKLHQEYGGK
GLNVLAVAMSYDPPNYVQNFVAKNQLPFFVALDPQGATAKAFGDIQLAPTTFLIDKQGNIIKRYVGVMNFAEVRKLIEQH
L

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 17315; Mature: 17315

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGLIIALALLVAAGAAYKLMFSGSPAPEVKLTSLTGAVTSTSALKGKVVLVNFWATSC
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCHHCCCCCCCEEEEEEECCCCC
PGCVEEMPEIKKLHQEYGGKGLNVLAVAMSYDPPNYVQNFVAKNQLPFFVALDPQGATAK
CHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCEE
AFGDIQLAPTTFLIDKQGNIIKRYVGVMNFAEVRKLIEQHL
ECCCEEECCEEEEEECCCCHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MKKGLIIALALLVAAGAAYKLMFSGSPAPEVKLTSLTGAVTSTSALKGKVVLVNFWATSC
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCHHCCCCCCCEEEEEEECCCCC
PGCVEEMPEIKKLHQEYGGKGLNVLAVAMSYDPPNYVQNFVAKNQLPFFVALDPQGATAK
CHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCEE
AFGDIQLAPTTFLIDKQGNIIKRYVGVMNFAEVRKLIEQHL
ECCCEEECCEEEEEECCCCHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA