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The map label for this gene is ytfL [H]

Identifier: 34499697

GI number: 34499697

Start: 4578841

End: 4580157

Strand: Reverse

Name: ytfL [H]

Synonym: CV_4242

Alternate gene names: 34499697

Gene position: 4580157-4578841 (Counterclockwise)

Preceding gene: 34499699

Following gene: 34499696

Centisome position: 96.4

GC content: 63.86

Gene sequence:

>1317_bases
GTGAGCCTTGCAAACAATCTTTCCATCATCCTCCTGCTGATCGCCGCCAGCGCCTTTTTCTCGGTGTCGGAGATTTCCCT
GGCCGCCGCGCGCAAGATCAAGCTCAGGCTGCTGGCGGAAGAGGGCAACCTCAACGCCGAGCGGGTGCTGGAGCTGCAGC
AGCAGCCGGGCCACTTCTTCACCGTGGTGCAGATCGGCCTGAACGCGGTGGCCATCCTGGCCGGCATCCTGGGCGAAGCG
GCGTTCACGCCCTATTTCGCCGCGATGCTGCATCTGGTGACGCCGGCGGGTTGGGTCGAGCACTTGAGCTTCGTGCTGTC
CTTCGCCGCCGTCACGTCGCTGTTCGTGCTGTTCGCCGACCTGATGCCGAAGCGGCTGGGCATGGTGGCGCCGGAGCGCA
TCGCGCTGCTGGTGGTGCGGCCGATGCTGTTCTGCGTCGCCCTGTTCCGGCCGCTGGTGTGGCTGTTCAATGGCCTGGCC
AACGTGTTTTTCCGCATGCTGGGGGTGCCGACCGCGCGGGCGGAGGATCTGACTCCGGCCGATCTGCTGGCGATGATGGA
CGCCGGCGCCGAGGCCGGCGTGCTGCAGCAGAAGGAGCACCACCTGATCGAAAACGTGTTCGAGCTGGAAAGCCGCACCG
TGCCTTCGTCGATGACCGCGCGCGAAAGCATCGTCTACTTCACGCTGCACGAGGACGAGGCCAGCATCAAGCAGAAGATC
GCCGAGCATCCGCACACCAAGTTCCTGGTCTGCGACGGCGTGATCGACTCGGTGATCGGCTATGTCGACTCCAAGGACAT
CCTGATGCGGCTGATCAACCAGCAGAGCCTGTCGATGAAGCGCGAGCTGACGATACGCAATGTGCTGATCATTCCCGATT
CGCTGACCTTGTCCGAGCTGTTGGAGCGCTTCAAGGCCTCGCGCGAGGACTTCGCCGTGGTGATGAACGAATACGCGCTG
GTGGTGGGCGTGATCACGCTGAACGACCTGATGAGCACCGTGATGGGCGACCTGGTCAGCCAGTTCCAGGAGGAACAGAT
CGTCCGCCGCGACGACCGCTCCTGGCTGGTGGACGGGGCGACTCCGGTGGAGGACGTGCTGCGCGCGCTGGACATCGAAT
CCTTCCCCGACGACGAGAACTACGAAACCATCGCCGGCTTCATGATGTACATGCTGCGGCGGATCCCCAAGCGCACCGAC
AGCGTGGAGTTCGAAGGCTACAAATTCGAGGTGGTGGACATCGACAACTACCGGATCGACCAGCTGCTGGTGACGCTGAT
CCCGCCGGCGCCGGCCGAAGGCGAGTCCGCCCGCTGA

Upstream 100 bases:

>100_bases
AAACGGCTCTGTTATACTGGACATCAAATCCATGCGTTCAGTCTCGCGAATCGGGTGGTCTTATTCGCGGCGGGGCGCAA
GCACTTGTTCGGGACTTATC

Downstream 100 bases:

>100_bases
CATTACGATTGGTTACACCCGCTTACACAGGCCTCACAGACGGGATGGGGCGGCCTGCCTACTATAGGTTCAAGGACGCC
GGAAACAGCGCCTCAGAAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MSLANNLSIILLLIAASAFFSVSEISLAAARKIKLRLLAEEGNLNAERVLELQQQPGHFFTVVQIGLNAVAILAGILGEA
AFTPYFAAMLHLVTPAGWVEHLSFVLSFAAVTSLFVLFADLMPKRLGMVAPERIALLVVRPMLFCVALFRPLVWLFNGLA
NVFFRMLGVPTARAEDLTPADLLAMMDAGAEAGVLQQKEHHLIENVFELESRTVPSSMTARESIVYFTLHEDEASIKQKI
AEHPHTKFLVCDGVIDSVIGYVDSKDILMRLINQQSLSMKRELTIRNVLIIPDSLTLSELLERFKASREDFAVVMNEYAL
VVGVITLNDLMSTVMGDLVSQFQEEQIVRRDDRSWLVDGATPVEDVLRALDIESFPDDENYETIAGFMMYMLRRIPKRTD
SVEFEGYKFEVVDIDNYRIDQLLVTLIPPAPAEGESAR

Sequences:

>Translated_438_residues
MSLANNLSIILLLIAASAFFSVSEISLAAARKIKLRLLAEEGNLNAERVLELQQQPGHFFTVVQIGLNAVAILAGILGEA
AFTPYFAAMLHLVTPAGWVEHLSFVLSFAAVTSLFVLFADLMPKRLGMVAPERIALLVVRPMLFCVALFRPLVWLFNGLA
NVFFRMLGVPTARAEDLTPADLLAMMDAGAEAGVLQQKEHHLIENVFELESRTVPSSMTARESIVYFTLHEDEASIKQKI
AEHPHTKFLVCDGVIDSVIGYVDSKDILMRLINQQSLSMKRELTIRNVLIIPDSLTLSELLERFKASREDFAVVMNEYAL
VVGVITLNDLMSTVMGDLVSQFQEEQIVRRDDRSWLVDGATPVEDVLRALDIESFPDDENYETIAGFMMYMLRRIPKRTD
SVEFEGYKFEVVDIDNYRIDQLLVTLIPPAPAEGESAR
>Mature_437_residues
SLANNLSIILLLIAASAFFSVSEISLAAARKIKLRLLAEEGNLNAERVLELQQQPGHFFTVVQIGLNAVAILAGILGEAA
FTPYFAAMLHLVTPAGWVEHLSFVLSFAAVTSLFVLFADLMPKRLGMVAPERIALLVVRPMLFCVALFRPLVWLFNGLAN
VFFRMLGVPTARAEDLTPADLLAMMDAGAEAGVLQQKEHHLIENVFELESRTVPSSMTARESIVYFTLHEDEASIKQKIA
EHPHTKFLVCDGVIDSVIGYVDSKDILMRLINQQSLSMKRELTIRNVLIIPDSLTLSELLERFKASREDFAVVMNEYALV
VGVITLNDLMSTVMGDLVSQFQEEQIVRRDDRSWLVDGATPVEDVLRALDIESFPDDENYETIAGFMMYMLRRIPKRTDS
VEFEGYKFEVVDIDNYRIDQLLVTLIPPAPAEGESAR

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=382, Percent_Identity=26.4397905759162, Blast_Score=166, Evalue=3e-41,
Organism=Escherichia coli, GI1790664, Length=423, Percent_Identity=65.7210401891253, Blast_Score=595, Evalue=1e-171,
Organism=Escherichia coli, GI145693175, Length=424, Percent_Identity=25, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI87082033, Length=256, Percent_Identity=31.25, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1788119, Length=243, Percent_Identity=27.5720164609054, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786879, Length=283, Percent_Identity=24.3816254416961, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48923; Mature: 48791

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLANNLSIILLLIAASAFFSVSEISLAAARKIKLRLLAEEGNLNAERVLELQQQPGHFF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHCCCCEE
TVVQIGLNAVAILAGILGEAAFTPYFAAMLHLVTPAGWVEHLSFVLSFAAVTSLFVLFAD
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LMPKRLGMVAPERIALLVVRPMLFCVALFRPLVWLFNGLANVFFRMLGVPTARAEDLTPA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
DLLAMMDAGAEAGVLQQKEHHLIENVFELESRTVPSSMTARESIVYFTLHEDEASIKQKI
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCEEEEEEEECCHHHHHHHH
AEHPHTKFLVCDGVIDSVIGYVDSKDILMRLINQQSLSMKRELTIRNVLIIPDSLTLSEL
HHCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHH
LERFKASREDFAVVMNEYALVVGVITLNDLMSTVMGDLVSQFQEEQIVRRDDRSWLVDGA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
TPVEDVLRALDIESFPDDENYETIAGFMMYMLRRIPKRTDSVEFEGYKFEVVDIDNYRID
CCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEECCEEEEEEECCCCCHH
QLLVTLIPPAPAEGESAR
HHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SLANNLSIILLLIAASAFFSVSEISLAAARKIKLRLLAEEGNLNAERVLELQQQPGHFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHCCCCEE
TVVQIGLNAVAILAGILGEAAFTPYFAAMLHLVTPAGWVEHLSFVLSFAAVTSLFVLFAD
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LMPKRLGMVAPERIALLVVRPMLFCVALFRPLVWLFNGLANVFFRMLGVPTARAEDLTPA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
DLLAMMDAGAEAGVLQQKEHHLIENVFELESRTVPSSMTARESIVYFTLHEDEASIKQKI
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCEEEEEEEECCHHHHHHHH
AEHPHTKFLVCDGVIDSVIGYVDSKDILMRLINQQSLSMKRELTIRNVLIIPDSLTLSEL
HHCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHH
LERFKASREDFAVVMNEYALVVGVITLNDLMSTVMGDLVSQFQEEQIVRRDDRSWLVDGA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
TPVEDVLRALDIESFPDDENYETIAGFMMYMLRRIPKRTDSVEFEGYKFEVVDIDNYRID
CCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEECCEEEEEEECCCCCHH
QLLVTLIPPAPAEGESAR
HHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]