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The map label for this gene is rpoC

Identifier: 34499647

GI number: 34499647

Start: 4520052

End: 4524242

Strand: Reverse

Name: rpoC

Synonym: CV_4192

Alternate gene names: 34499647

Gene position: 4524242-4520052 (Counterclockwise)

Preceding gene: 34499648

Following gene: 34499646

Centisome position: 95.23

GC content: 62.92

Gene sequence:

>4191_bases
ATGAAAGCTTTGCTCGATCTCTTTAAGCAAGTTACGCAAGAAGAAGAGTTTGATGCGATCAAGATCGGCATCGCCTCGCC
TGACAAGATCCGTTCCTGGTCTTATGGCGAAGTCAAGAAGCCGGAAACCATCAACTACCGTACCTTCAAGCCGGAGCGCG
ACGGCCTGTTCTGCGCGCGCATCTTCGGCCCGGTGAAGGACTACGAGTGCTTGTGCGGCAAGTACAAGCGCCTGAAGCAT
CGCGGCGTGATCTGCGAGAAGTGCGGCGTCGAAGTGACGCTGTCCAAGGTGCGCCGCGAGCGCATGGGCCACATCGAGCT
GGCCAGCCCGACCGCCCACATCTGGTTCCTGAAGTCGCTGCCGTCACGCCTGGGCATGGTGCTGGACATGACGCTGCGCG
ACATCGAGCGCGTGCTGTATTTCGAAGCGTACGTCGTGACCGATCCGGGCATGACCCCGATGCAGTACCGCCAGCTCCTG
ACCGAAGAGGACTTCCTGGACAAGGAAGACCAGTACGGTGAAGAGTTCGTCGCCATGATGGGCGCCGAGGCCGTCAAGGA
ACTGCTGAAGAAGCTGGATCTGGACGCCGAGATCGAAGGCCTGCGCCGCGAGCTGGAAACCACCAACTCCGACACCAAGA
TCAAGAAGATCGCCAAGCGCCTGAAGGTGCTGGAGGCGTTCCAGCGTTCCGGCATGAAGCCGGAGTGGATGATCCTGGAA
GTGCTGCCGGTGCTGCCGCCGGAACTGCGTCCGCTGGTGCCGCTGGACGGCGGTCGTTTCGCGACCTCCGACCTGAACGA
CCTGTACCGCCGCGTGATCAACCGTAACAACCGTCTGAAGCGTCTGCTGGAACTGCGCGCGCCGGACATCATCGTGCGCA
ACGAAAAGCGCATGCTGCAGGAATCGGTTGACTCGCTGCTGGACAACGGTCGTCGCGGCAAGGCCATGACCGGCGCCAAC
AAGCGCCCGCTGAAGTCGCTGGCCGACATGATCAAGGGCAAGGGCGGTCGCTTCCGTCAGAACTTGCTGGGTAAGCGCGT
GGACTACTCCGGTCGTTCCGTGATTACCGTGGGCCCGACCCTGCGTCTGCATCAGTGCGGCCTGCCGAAGAAGATGGCGC
TGGAGCTGTTCAAGCCGTTCATCTTCCACAAGCTGGAAGTGATGGGCCTGGCGTCCACCATCAAGGCTGCCAAGAAGCTG
GTCGAGCAGGAAGTGCCGGAAGTCTGGGACATCCTCGAAGAAGTGATCCGCGAGCATCCGGTGCTGCTGAACCGCGCCCC
GACGCTGCACCGCCTGGGCATCCAGGCGTTCGAGCCGGTGCTGATCGAAGGCAAGGCGATCCAGCTGCATCCGCTGGTCT
GCGCGGCGTTCAACGCCGACTTCGACGGCGACCAGATGGCCGTCCACGTGCCGCTGTCGCTGGAAGCGCAGATGGAGGCC
CGCACCCTGATGCTGGCCACCAACAACGTGCTGTCTCCGGCCAACGGCGAGCCGATCATCGTGCCGTCGCAGGATATCGT
GCTGGGTCTCTATTACATGACCCGCGACAAGGTGAACGGCAAGGGCGAGGGCATGGTGTTTGCGGACACCAAGGAAGTGC
ATCGCGCTTACGAAACCCGCCAGGTCGAGCTGGCCACCCGCATCACCGTCCGCCTGAAGGAATGGGAAAAGGACGAGCAG
GGCGAGTTCCAGCCGGTGATCAAGCGCTATAACACCACCGTCGGCCGCGCGATCCTGTCGGACATCCTGCCGAAGGGCCT
GCCGTTCGAGCACATCAACAAGGCGCTGAAGAAGAAGGAAATCTCCAAGCTGATCAACGTGTCGTTCCGCCGTTGCGGCA
TCCGCGATACCGTGATCTTCGCCGACCAGCTGATGTACACCGGCTTCGCCTACTCCACCCGCGGCGGCATCTCCATCTGC
GTGGACGACATGCAGATTCCGGTCAAGAAGAGCGAACTGCTCGGCGAGGCCAACAAGGAAGTCAAGGAGATCGAGGAGCA
GTACCGTCAAGGCCTGGTGACCCAGGGCGAACGCTACAACAAGGTAGTGGACATCTGGGGCCGCACCGGCGACAAGATCG
CCAAGGCGATGATGGACGAGCTGTCCAAGCAGAAGGTGCTGGACCGCGAAGGCAAGGAAGTCGATCAGGAATCCTTCAAC
TCCATTTACATGATGGCCGACTCGGGCGCGCGGGGTTCTGCAGCCCAGATCAAGCAGCTGGCCGGCATGCGGGGTCTGAT
GGCGAAGCCGGACGGCTCGATTATCGAAACGCCGATTACCGCCAACTTCCGCGAAGGTCTGACCGTACTCCAGTACTTCA
TCTCGACCCACGGCGCCCGTAAGGGTCTGGCGGATACGGCCTTGAAGACCGCCAACTCCGGTTACCTGACCCGTCGTCTG
GTCGACGTGACCCAGGATCTGGTGGTGATCGAAGACGATTGCGGCACCAGCAACGGCTTCACCATGAAGGCGGTGCTGCA
GGGCGGCGACGTGATCGAGGCGCTGCGCGACCGTATCCTCGGCCGCGTGACCGCGGTCGACGTGGTGGATCCGTCCACCG
GCGAAACCGTGATCGAAGCCGGCACCCTGATGGATGAGCATCTGGTGGATCTGGTCGACAGTCTCGGCATCGACGAAGTC
AAGGTCCGCACCGCGATCACTTGCGACACCCGCTACGGCCTGTGCGCCAAGTGCTACGGCCGCGACCTGGCGCGCGGCAA
GCAGGTGAACGCCGGCGAAGCGATCGGCGTGATCGCCGCCCAGTCCATCGGCGAACCGGGCACCCAGCTGACCATGCGTA
CCTTCCACATCGGTGGCGCGGCATCGCGAAACGCGGCCGCCAGCCAGGTGGAAGGCAAGTCCAACGGCACCGTGCGCTTC
TCCAGCCAGATGCGCTACGTGGCCAACACCAAGGGCGAGCTGATCGTCATCACCCGCTCCGGCGAAGTGGTGATCCATGA
CGACATGGGCCGCGAGCGCGAGCGCCGCAAGGTGCCGTACGGCGCGACCCTGATGGTGACCGACGGTCTGCAGATCAAGG
CTGGCGCCGTGCTGGCCACCTGGGATCCGCACACCCGTCCGATCATCACCGAGTACGCCGGCCGCGTGAAGTTCGAGAAC
GTGGAAGAGGGCAACACCGTCGCCAAGCAGACCGACGAAGTGACCGGCCTGTCGACGCTGGTGGTCATCGATCCGAAGCG
CCGCGCGGGTTCGCAGTCCAAGATGCTGCGTCCGCTGGTGAAGCTGCTCGACGACAACGGCAACGAAGTGAAGCTGGCCG
GTTCCGACGCCTCGGTATCGATCACCTTCCAAGTCGGCGCCATCATCACCGTGCGCGACGGTCAGGACGTGGGCAAGGGC
GAAGTGCTGGCCCGCATCCCGCAGGAATCGTCGAAGACCCGCGACATTACCGGCGGTCTGCCGCGCGTGGCCGAGCTGTT
CGAAGCCCGTTCGCCGAAGGATGCCGGCATGCTGGCCGAGGTGACCGGTACCGTTTCGTTCGGCAAGGACACCAAGGGCA
AGCAGCGCCTGATCATCACCGACCTGGAAGGCAACGGTTACGAAAACCTGATTCCGAAGGACAAGCACGTGCTGGTCCAC
GACGGTCAGGTGGTGAACCGCGGCGAATCCATCGTCGACGGTCCGGTCGATCCGCACGACATCCTGCGCCTGCAGGGCAT
CGAGGCGCTGGCCCGCTACATCGTCCAGGAAGTGCAGGAGGTGTATCGTCTGCAGGGCGTGAAGATCAACGACAAGCACA
TCGAGGTGATCATCCGCCAGATGCTGCGTCGCGTGATCATTACCGACAGCGGCGACACCGAGTTCATCCAGGGCGAGCAG
GTGGAGCGCGCCGACGTGCTGGAAATGAACGACAAGATGATGGCGGAAAACAAGGAGCCGGCGCAGTACGAAAACGTGCT
GCTGGGCATCACCAAGGCTTCGCTGTCGACCGACTCGTTCATCTCCGCGGCTTCCTTCCAGGAAACCACGCGCGTGCTGA
CCGAAGCCGCCATCATGGGCAAGCGCGACGATCTGCGCGGTCTGAAGGAAAACGTGATCGTCGGCCGTCTGATCCCGGCC
GGCACCGGTCTCGCCTACCATCGCACCCGCCGCCGCCAGAACCTGGGTCTGGACGCTGGCGAGTCCATGCTGTTCGATCC
GGCCCCGGCGGCGCTGGAAAGCGGCGAATAA

Upstream 100 bases:

>100_bases
AATCCGCTCGCTCGGCCTCGACATGGACCTGGAACGTTATTGATTGGGTAATAGGGCGCGGCGGAATGCCGCCGCGCCTG
TCCCCTGAACTGGAGACGCA

Downstream 100 bases:

>100_bases
GCTGGGCCTCGCGGCCAAGTGTTGAAAAAACGCTGCTCCATCAACGGTTAACGTTGCTGGGGCGGCGTTTTTTATTTGAC
GCTTGACCGTTGACTAAAAT

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1396; Mature: 1396

Protein sequence:

>1396_residues
MKALLDLFKQVTQEEEFDAIKIGIASPDKIRSWSYGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTLSKVRRERMGHIELASPTAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVTDPGMTPMQYRQLL
TEEDFLDKEDQYGEEFVAMMGAEAVKELLKKLDLDAEIEGLRRELETTNSDTKIKKIAKRLKVLEAFQRSGMKPEWMILE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELRAPDIIVRNEKRMLQESVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIFHKLEVMGLASTIKAAKKL
VEQEVPEVWDILEEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
RTLMLATNNVLSPANGEPIIVPSQDIVLGLYYMTRDKVNGKGEGMVFADTKEVHRAYETRQVELATRITVRLKEWEKDEQ
GEFQPVIKRYNTTVGRAILSDILPKGLPFEHINKALKKKEISKLINVSFRRCGIRDTVIFADQLMYTGFAYSTRGGISIC
VDDMQIPVKKSELLGEANKEVKEIEEQYRQGLVTQGERYNKVVDIWGRTGDKIAKAMMDELSKQKVLDREGKEVDQESFN
SIYMMADSGARGSAAQIKQLAGMRGLMAKPDGSIIETPITANFREGLTVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVTQDLVVIEDDCGTSNGFTMKAVLQGGDVIEALRDRILGRVTAVDVVDPSTGETVIEAGTLMDEHLVDLVDSLGIDEV
KVRTAITCDTRYGLCAKCYGRDLARGKQVNAGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRNAAASQVEGKSNGTVRF
SSQMRYVANTKGELIVITRSGEVVIHDDMGRERERRKVPYGATLMVTDGLQIKAGAVLATWDPHTRPIITEYAGRVKFEN
VEEGNTVAKQTDEVTGLSTLVVIDPKRRAGSQSKMLRPLVKLLDDNGNEVKLAGSDASVSITFQVGAIITVRDGQDVGKG
EVLARIPQESSKTRDITGGLPRVAELFEARSPKDAGMLAEVTGTVSFGKDTKGKQRLIITDLEGNGYENLIPKDKHVLVH
DGQVVNRGESIVDGPVDPHDILRLQGIEALARYIVQEVQEVYRLQGVKINDKHIEVIIRQMLRRVIITDSGDTEFIQGEQ
VERADVLEMNDKMMAENKEPAQYENVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPA
GTGLAYHRTRRRQNLGLDAGESMLFDPAPAALESGE

Sequences:

>Translated_1396_residues
MKALLDLFKQVTQEEEFDAIKIGIASPDKIRSWSYGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTLSKVRRERMGHIELASPTAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVTDPGMTPMQYRQLL
TEEDFLDKEDQYGEEFVAMMGAEAVKELLKKLDLDAEIEGLRRELETTNSDTKIKKIAKRLKVLEAFQRSGMKPEWMILE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELRAPDIIVRNEKRMLQESVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIFHKLEVMGLASTIKAAKKL
VEQEVPEVWDILEEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
RTLMLATNNVLSPANGEPIIVPSQDIVLGLYYMTRDKVNGKGEGMVFADTKEVHRAYETRQVELATRITVRLKEWEKDEQ
GEFQPVIKRYNTTVGRAILSDILPKGLPFEHINKALKKKEISKLINVSFRRCGIRDTVIFADQLMYTGFAYSTRGGISIC
VDDMQIPVKKSELLGEANKEVKEIEEQYRQGLVTQGERYNKVVDIWGRTGDKIAKAMMDELSKQKVLDREGKEVDQESFN
SIYMMADSGARGSAAQIKQLAGMRGLMAKPDGSIIETPITANFREGLTVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVTQDLVVIEDDCGTSNGFTMKAVLQGGDVIEALRDRILGRVTAVDVVDPSTGETVIEAGTLMDEHLVDLVDSLGIDEV
KVRTAITCDTRYGLCAKCYGRDLARGKQVNAGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRNAAASQVEGKSNGTVRF
SSQMRYVANTKGELIVITRSGEVVIHDDMGRERERRKVPYGATLMVTDGLQIKAGAVLATWDPHTRPIITEYAGRVKFEN
VEEGNTVAKQTDEVTGLSTLVVIDPKRRAGSQSKMLRPLVKLLDDNGNEVKLAGSDASVSITFQVGAIITVRDGQDVGKG
EVLARIPQESSKTRDITGGLPRVAELFEARSPKDAGMLAEVTGTVSFGKDTKGKQRLIITDLEGNGYENLIPKDKHVLVH
DGQVVNRGESIVDGPVDPHDILRLQGIEALARYIVQEVQEVYRLQGVKINDKHIEVIIRQMLRRVIITDSGDTEFIQGEQ
VERADVLEMNDKMMAENKEPAQYENVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPA
GTGLAYHRTRRRQNLGLDAGESMLFDPAPAALESGE
>Mature_1396_residues
MKALLDLFKQVTQEEEFDAIKIGIASPDKIRSWSYGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTLSKVRRERMGHIELASPTAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVTDPGMTPMQYRQLL
TEEDFLDKEDQYGEEFVAMMGAEAVKELLKKLDLDAEIEGLRRELETTNSDTKIKKIAKRLKVLEAFQRSGMKPEWMILE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELRAPDIIVRNEKRMLQESVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIFHKLEVMGLASTIKAAKKL
VEQEVPEVWDILEEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
RTLMLATNNVLSPANGEPIIVPSQDIVLGLYYMTRDKVNGKGEGMVFADTKEVHRAYETRQVELATRITVRLKEWEKDEQ
GEFQPVIKRYNTTVGRAILSDILPKGLPFEHINKALKKKEISKLINVSFRRCGIRDTVIFADQLMYTGFAYSTRGGISIC
VDDMQIPVKKSELLGEANKEVKEIEEQYRQGLVTQGERYNKVVDIWGRTGDKIAKAMMDELSKQKVLDREGKEVDQESFN
SIYMMADSGARGSAAQIKQLAGMRGLMAKPDGSIIETPITANFREGLTVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVTQDLVVIEDDCGTSNGFTMKAVLQGGDVIEALRDRILGRVTAVDVVDPSTGETVIEAGTLMDEHLVDLVDSLGIDEV
KVRTAITCDTRYGLCAKCYGRDLARGKQVNAGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRNAAASQVEGKSNGTVRF
SSQMRYVANTKGELIVITRSGEVVIHDDMGRERERRKVPYGATLMVTDGLQIKAGAVLATWDPHTRPIITEYAGRVKFEN
VEEGNTVAKQTDEVTGLSTLVVIDPKRRAGSQSKMLRPLVKLLDDNGNEVKLAGSDASVSITFQVGAIITVRDGQDVGKG
EVLARIPQESSKTRDITGGLPRVAELFEARSPKDAGMLAEVTGTVSFGKDTKGKQRLIITDLEGNGYENLIPKDKHVLVH
DGQVVNRGESIVDGPVDPHDILRLQGIEALARYIVQEVQEVYRLQGVKINDKHIEVIIRQMLRRVIITDSGDTEFIQGEQ
VERADVLEMNDKMMAENKEPAQYENVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPA
GTGLAYHRTRRRQNLGLDAGESMLFDPAPAALESGE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI39725938, Length=1028, Percent_Identity=25.4863813229572, Blast_Score=187, Evalue=6e-47,
Organism=Homo sapiens, GI4505939, Length=938, Percent_Identity=25.2665245202559, Blast_Score=184, Evalue=4e-46,
Organism=Homo sapiens, GI103471997, Length=225, Percent_Identity=30.6666666666667, Blast_Score=87, Evalue=1e-16,
Organism=Escherichia coli, GI2367335, Length=1392, Percent_Identity=68.4626436781609, Blast_Score=1942, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=570, Percent_Identity=26.6666666666667, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI25145495, Length=331, Percent_Identity=30.2114803625378, Blast_Score=140, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6320061, Length=923, Percent_Identity=23.726977248104, Blast_Score=191, Evalue=8e-49,
Organism=Saccharomyces cerevisiae, GI6324690, Length=343, Percent_Identity=30.6122448979592, Blast_Score=138, Evalue=6e-33,
Organism=Drosophila melanogaster, GI281360912, Length=1027, Percent_Identity=25.3164556962025, Blast_Score=194, Evalue=3e-49,
Organism=Drosophila melanogaster, GI17530899, Length=571, Percent_Identity=27.1453590192644, Blast_Score=155, Evalue=2e-37,
Organism=Drosophila melanogaster, GI17647875, Length=329, Percent_Identity=27.9635258358663, Blast_Score=106, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_CHRVO (Q7NQE7)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903862.1
- ProteinModelPortal:   Q7NQE7
- GeneID:   2548951
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_4192
- NMPDR:   fig|243365.1.peg.4192
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   Q7NQE7
- ProtClustDB:   PRK00566
- BioCyc:   CVIO243365:CV_4192-MONOMER
- BRENDA:   2.7.7.6
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 155295; Mature: 155295

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLDLFKQVTQEEEFDAIKIGIASPDKIRSWSYGEVKKPETINYRTFKPERDGLFCAR
CHHHHHHHHHHHCCCCCCEEEEECCCCHHCCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTLSKVRRERMGHIELASPTAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHCCCEEECCCCEEEHHHHHH
PSRLGMVLDMTLRDIERVLYFEAYVVTDPGMTPMQYRQLLTEEDFLDKEDQYGEEFVAMM
HHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GAEAVKELLKKLDLDAEIEGLRRELETTNSDTKIKKIAKRLKVLEAFQRSGMKPEWMILE
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHEE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELRAPDIIVRNEKRMLQ
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
ESVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVITVGPT
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFIFHKLEVMGLASTIKAAKKLVEQEVPEVWDILEEVIREHP
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
EEECCCCCHHHHCHHHCCCEEECCCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCCCC
RTLMLATNNVLSPANGEPIIVPSQDIVLGLYYMTRDKVNGKGEGMVFADTKEVHRAYETR
EEEEEEECCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCEEEEECHHHHHHHHHHH
QVELATRITVRLKEWEKDEQGEFQPVIKRYNTTVGRAILSDILPKGLPFEHINKALKKKE
HEEEEHEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ISKLINVSFRRCGIRDTVIFADQLMYTGFAYSTRGGISICVDDMQIPVKKSELLGEANKE
HHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHH
VKEIEEQYRQGLVTQGERYNKVVDIWGRTGDKIAKAMMDELSKQKVLDREGKEVDQESFN
HHHHHHHHHCCCCCCCCHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCC
SIYMMADSGARGSAAQIKQLAGMRGLMAKPDGSIIETPITANFREGLTVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDVTQDLVVIEDDCGTSNGFTMKAVLQGGDVIEALRDRIL
CCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHH
GRVTAVDVVDPSTGETVIEAGTLMDEHLVDLVDSLGIDEVKVRTAITCDTRYGLCAKCYG
HHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHC
RDLARGKQVNAGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRNAAASQVEGKSNGTVRF
CHHHCCCCCCCCCCEEHEEHHCCCCCCCEEEEEEEEECCCCCCCCHHHHCCCCCCCEEEE
SSQMRYVANTKGELIVITRSGEVVIHDDMGRERERRKVPYGATLMVTDGLQIKAGAVLAT
CCCCCEEECCCCCEEEEEECCCEEEECCCCCHHHHHCCCCCEEEEEECCEEEECCEEEEE
WDPHTRPIITEYAGRVKFENVEEGNTVAKQTDEVTGLSTLVVIDPKRRAGSQSKMLRPLV
CCCCCCCHHHHHCCCCEECCCCCCCHHHHHHHCCCCCEEEEEECCCHHCCCHHHHHHHHH
KLLDDNGNEVKLAGSDASVSITFQVGAIITVRDGQDVGKGEVLARIPQESSKTRDITGGL
HHHCCCCCEEEEECCCCEEEEEEEEEEEEEEECCCCCCCCHHEEECCCCCCCCCCCCCCC
PRVAELFEARSPKDAGMLAEVTGTVSFGKDTKGKQRLIITDLEGNGYENLIPKDKHVLVH
HHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEE
DGQVVNRGESIVDGPVDPHDILRLQGIEALARYIVQEVQEVYRLQGVKINDKHIEVIIRQ
CCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHH
MLRRVIITDSGDTEFIQGEQVERADVLEMNDKMMAENKEPAQYENVLLGITKASLSTDSF
HHHHHEECCCCCCCCCCCCCCCHHHHHHCCCHHHHCCCCCHHHHHEEEEEEHHCCCCHHH
ISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAYHRTRRRQNLGLDAG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCCCC
ESMLFDPAPAALESGE
CCCEECCCCCCCCCCC
>Mature Secondary Structure
MKALLDLFKQVTQEEEFDAIKIGIASPDKIRSWSYGEVKKPETINYRTFKPERDGLFCAR
CHHHHHHHHHHHCCCCCCEEEEECCCCHHCCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTLSKVRRERMGHIELASPTAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHCCCEEECCCCEEEHHHHHH
PSRLGMVLDMTLRDIERVLYFEAYVVTDPGMTPMQYRQLLTEEDFLDKEDQYGEEFVAMM
HHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GAEAVKELLKKLDLDAEIEGLRRELETTNSDTKIKKIAKRLKVLEAFQRSGMKPEWMILE
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHEE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELRAPDIIVRNEKRMLQ
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
ESVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVITVGPT
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFIFHKLEVMGLASTIKAAKKLVEQEVPEVWDILEEVIREHP
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEA
EEECCCCCHHHHCHHHCCCEEECCCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCCCC
RTLMLATNNVLSPANGEPIIVPSQDIVLGLYYMTRDKVNGKGEGMVFADTKEVHRAYETR
EEEEEEECCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCEEEEECHHHHHHHHHHH
QVELATRITVRLKEWEKDEQGEFQPVIKRYNTTVGRAILSDILPKGLPFEHINKALKKKE
HEEEEHEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ISKLINVSFRRCGIRDTVIFADQLMYTGFAYSTRGGISICVDDMQIPVKKSELLGEANKE
HHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHH
VKEIEEQYRQGLVTQGERYNKVVDIWGRTGDKIAKAMMDELSKQKVLDREGKEVDQESFN
HHHHHHHHHCCCCCCCCHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCC
SIYMMADSGARGSAAQIKQLAGMRGLMAKPDGSIIETPITANFREGLTVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDVTQDLVVIEDDCGTSNGFTMKAVLQGGDVIEALRDRIL
CCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHH
GRVTAVDVVDPSTGETVIEAGTLMDEHLVDLVDSLGIDEVKVRTAITCDTRYGLCAKCYG
HHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHC
RDLARGKQVNAGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRNAAASQVEGKSNGTVRF
CHHHCCCCCCCCCCEEHEEHHCCCCCCCEEEEEEEEECCCCCCCCHHHHCCCCCCCEEEE
SSQMRYVANTKGELIVITRSGEVVIHDDMGRERERRKVPYGATLMVTDGLQIKAGAVLAT
CCCCCEEECCCCCEEEEEECCCEEEECCCCCHHHHHCCCCCEEEEEECCEEEECCEEEEE
WDPHTRPIITEYAGRVKFENVEEGNTVAKQTDEVTGLSTLVVIDPKRRAGSQSKMLRPLV
CCCCCCCHHHHHCCCCEECCCCCCCHHHHHHHCCCCCEEEEEECCCHHCCCHHHHHHHHH
KLLDDNGNEVKLAGSDASVSITFQVGAIITVRDGQDVGKGEVLARIPQESSKTRDITGGL
HHHCCCCCEEEEECCCCEEEEEEEEEEEEEEECCCCCCCCHHEEECCCCCCCCCCCCCCC
PRVAELFEARSPKDAGMLAEVTGTVSFGKDTKGKQRLIITDLEGNGYENLIPKDKHVLVH
HHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEE
DGQVVNRGESIVDGPVDPHDILRLQGIEALARYIVQEVQEVYRLQGVKINDKHIEVIIRQ
CCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHH
MLRRVIITDSGDTEFIQGEQVERADVLEMNDKMMAENKEPAQYENVLLGITKASLSTDSF
HHHHHEECCCCCCCCCCCCCCCHHHHHHCCCHHHHCCCCCHHHHHEEEEEEHHCCCCHHH
ISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAYHRTRRRQNLGLDAG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCCCC
ESMLFDPAPAALESGE
CCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782