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The map label for this gene is secY [H]

Identifier: 34499621

GI number: 34499621

Start: 4504896

End: 4506215

Strand: Reverse

Name: secY [H]

Synonym: CV_4166

Alternate gene names: 34499621

Gene position: 4506215-4504896 (Counterclockwise)

Preceding gene: 34499622

Following gene: 161594048

Centisome position: 94.85

GC content: 56.97

Gene sequence:

>1320_bases
GTGGCGAATACTTCTCTAGTGGCCAATGCCAATAAGTTTGGTGATCTGAAGCGTCGTATCTGGTTCCTGATTGGCGCGCT
GATCGTTTATCGCATCGGCGCCCATATTCCGGTTCCGGGTATCAACCCTGCCGAACTAGCGAAGTTGTTCCACACATCGC
AGACGGGCCTGCTCGACATGTTCAACATGTTCTCGGGCGGCGCCCTCTCGAGGTTTACGGTATTTGCCCTGGGCATCATG
CCGTACATCTCGGCTTCCATCATTCTGCAGCTTGCGGCCGAGGTTCTGCCCAGCCTGAAGCAGTTGAAGAAGGAAGGCGA
TGCGGGACGTCGCAAGATAACCCAGTACACGCGTTATGCCACCGTGGCGCTCGCAACTTTCCAAAGTTTCGGCATCGCGG
TGATGTTGTACAAGCAGCCTAACCTGGTGATGACTGCTCAGTGGGAGTTTTATCTGACAACCGTGGTGTCTCTGGTCACC
GGAACCATGTTCCTGATGTGGTTGGGCGAACAGATCACCGAGCGCGGTATCGGCAACGGTATCTCGCTGATCATCTGCGC
GGGTATCGCCGCGGGTGTTCCGGCTGCGATCGGTAAAACCCTGACTCTGACCAGTCAGGGCTCCTTGCCCATTCTGTTTG
CCATCCTGCTGTTTGTCGGTGTGATCCTGGTCACCTTCCTCGTTGTCTACGCCGAGCGCGGCCAACGCAAGGTGCTGGTG
AACTACGCCAAGCGTCAGGTGGGCAATCGCGTCATGCAGGGCCAGAGCACGCATCTGCCGCTCAAGCTCAACATGGCAGG
GGTGATTCCCCCGATCTTCGCCTCCAGCATCATCCTGTTCCCGGCCACCGTTCTCGGCTGGTTCGGCCAGGGCGAGCACA
TGGCTTGGTTGAAGGGCGTGGCCGACAAGCTGCACCCGGGTCAGCCGATCTATGTGCTGCTGTATGCGGCGGCGATCATC
TTCTTCTGCTATTTCTACACGGCGTTGGTATTCAACCCCAAGGAAACGGCTGACAACCTGAAGAAGAGCGGGGCGTTCAT
CCCGGGCATCCGTCCAGGTGAGCAGACTTCTCGTTACATCGAGAAGATCATTCTGCGGCTGACGCTGATCGGTGCGATCT
ACATCACGCTGGTCTGCCTGCTGCCGGAATTCCTGATCCTGAAGTGGAACGTGCCGTTCTACTTCGGCGGTACGTCGCTG
CTGATTATCGTGGTGGTGACGATGGACTTCATGGCGCAAGTGCAGTCCTATGTGTTGTCGCATCAATACGAGAGCTTGCT
GAAGAAGGCCAACTTCAAAGGCAATGCCCTTACCCGCTGA

Upstream 100 bases:

>100_bases
AGGTTGAGCGCGCGGTCAAACTGCGTGGTATCAGCGTTACCGCTGGCGCCCGCGCTGCCATCGAGGCTGCCGGCGGCAGC
ATTGAATAAGGCATAAATTT

Downstream 100 bases:

>100_bases
CACACGAGTTCACACTGGGTTATATGGCTAAGGAAGACACTATCCAGATGCAGGGCGAGGTCCTGGAAAATTTGCCCAGC
GCAACTTTCAAGATCAAGCT

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MANTSLVANANKFGDLKRRIWFLIGALIVYRIGAHIPVPGINPAELAKLFHTSQTGLLDMFNMFSGGALSRFTVFALGIM
PYISASIILQLAAEVLPSLKQLKKEGDAGRRKITQYTRYATVALATFQSFGIAVMLYKQPNLVMTAQWEFYLTTVVSLVT
GTMFLMWLGEQITERGIGNGISLIICAGIAAGVPAAIGKTLTLTSQGSLPILFAILLFVGVILVTFLVVYAERGQRKVLV
NYAKRQVGNRVMQGQSTHLPLKLNMAGVIPPIFASSIILFPATVLGWFGQGEHMAWLKGVADKLHPGQPIYVLLYAAAII
FFCYFYTALVFNPKETADNLKKSGAFIPGIRPGEQTSRYIEKIILRLTLIGAIYITLVCLLPEFLILKWNVPFYFGGTSL
LIIVVVTMDFMAQVQSYVLSHQYESLLKKANFKGNALTR

Sequences:

>Translated_439_residues
MANTSLVANANKFGDLKRRIWFLIGALIVYRIGAHIPVPGINPAELAKLFHTSQTGLLDMFNMFSGGALSRFTVFALGIM
PYISASIILQLAAEVLPSLKQLKKEGDAGRRKITQYTRYATVALATFQSFGIAVMLYKQPNLVMTAQWEFYLTTVVSLVT
GTMFLMWLGEQITERGIGNGISLIICAGIAAGVPAAIGKTLTLTSQGSLPILFAILLFVGVILVTFLVVYAERGQRKVLV
NYAKRQVGNRVMQGQSTHLPLKLNMAGVIPPIFASSIILFPATVLGWFGQGEHMAWLKGVADKLHPGQPIYVLLYAAAII
FFCYFYTALVFNPKETADNLKKSGAFIPGIRPGEQTSRYIEKIILRLTLIGAIYITLVCLLPEFLILKWNVPFYFGGTSL
LIIVVVTMDFMAQVQSYVLSHQYESLLKKANFKGNALTR
>Mature_438_residues
ANTSLVANANKFGDLKRRIWFLIGALIVYRIGAHIPVPGINPAELAKLFHTSQTGLLDMFNMFSGGALSRFTVFALGIMP
YISASIILQLAAEVLPSLKQLKKEGDAGRRKITQYTRYATVALATFQSFGIAVMLYKQPNLVMTAQWEFYLTTVVSLVTG
TMFLMWLGEQITERGIGNGISLIICAGIAAGVPAAIGKTLTLTSQGSLPILFAILLFVGVILVTFLVVYAERGQRKVLVN
YAKRQVGNRVMQGQSTHLPLKLNMAGVIPPIFASSIILFPATVLGWFGQGEHMAWLKGVADKLHPGQPIYVLLYAAAIIF
FCYFYTALVFNPKETADNLKKSGAFIPGIRPGEQTSRYIEKIILRLTLIGAIYITLVCLLPEFLILKWNVPFYFGGTSLL
IIVVVTMDFMAQVQSYVLSHQYESLLKKANFKGNALTR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=424, Percent_Identity=66.9811320754717, Blast_Score=532, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48333; Mature: 48202

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTSLVANANKFGDLKRRIWFLIGALIVYRIGAHIPVPGINPAELAKLFHTSQTGLLDM
CCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHH
FNMFSGGALSRFTVFALGIMPYISASIILQLAAEVLPSLKQLKKEGDAGRRKITQYTRYA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TVALATFQSFGIAVMLYKQPNLVMTAQWEFYLTTVVSLVTGTMFLMWLGEQITERGIGNG
HHHHHHHHHCCEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ISLIICAGIAAGVPAAIGKTLTLTSQGSLPILFAILLFVGVILVTFLVVYAERGQRKVLV
HHHHHHHHHHHCCHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
NYAKRQVGNRVMQGQSTHLPLKLNMAGVIPPIFASSIILFPATVLGWFGQGEHMAWLKGV
HHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ADKLHPGQPIYVLLYAAAIIFFCYFYTALVFNPKETADNLKKSGAFIPGIRPGEQTSRYI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHH
EKIILRLTLIGAIYITLVCLLPEFLILKWNVPFYFGGTSLLIIVVVTMDFMAQVQSYVLS
HHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
HQYESLLKKANFKGNALTR
HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ANTSLVANANKFGDLKRRIWFLIGALIVYRIGAHIPVPGINPAELAKLFHTSQTGLLDM
CCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHH
FNMFSGGALSRFTVFALGIMPYISASIILQLAAEVLPSLKQLKKEGDAGRRKITQYTRYA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TVALATFQSFGIAVMLYKQPNLVMTAQWEFYLTTVVSLVTGTMFLMWLGEQITERGIGNG
HHHHHHHHHCCEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ISLIICAGIAAGVPAAIGKTLTLTSQGSLPILFAILLFVGVILVTFLVVYAERGQRKVLV
HHHHHHHHHHHCCHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
NYAKRQVGNRVMQGQSTHLPLKLNMAGVIPPIFASSIILFPATVLGWFGQGEHMAWLKGV
HHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ADKLHPGQPIYVLLYAAAIIFFCYFYTALVFNPKETADNLKKSGAFIPGIRPGEQTSRYI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHH
EKIILRLTLIGAIYITLVCLLPEFLILKWNVPFYFGGTSLLIIVVVTMDFMAQVQSYVLS
HHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHH
HQYESLLKKANFKGNALTR
HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9322765; 10952301 [H]