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The map label for this gene is mocR [H]

Identifier: 34499551

GI number: 34499551

Start: 4431972

End: 4433426

Strand: Direct

Name: mocR [H]

Synonym: CV_4096

Alternate gene names: 34499551

Gene position: 4431972-4433426 (Clockwise)

Preceding gene: 34499547

Following gene: 34499552

Centisome position: 93.28

GC content: 64.12

Gene sequence:

>1455_bases
TTGGACAATGATTGGATAGCCGATTACCTGAGGCCGAGGCTGGCGCGCGACAACGGCGAACACCTGTCGCGACAGCTCTA
CCGCCAGCTGCGCGAACTGATAGGCCAACGCCGGCTGGCTGGCGGCAGCGTACTGCCCGCTAGCCGCGCGCTGGCCCAGG
CCATGCAGCTGGGGCGCAATACCGTGCTCTCCGCCTACGACCAATTGGCAGCCGAAGGCTATCTGGAAAGTCGCCACGGC
TCCGGCACCTACGTCTGCGACGTCTTCACCAACAGTACCTCGCAAACCAGCCATTCCACCGCGCCTGCGCGCCCACTCTC
CCAGCGCGGCCAACGCCTGACCGCAAGCAGCCGGCTGCCGGTCCGCAAGCTCGGCGCCTTCGTGCCAGGCCTGCCTGAAC
TGGAACTGTTCCCGCACAAGGCATGGCAACAGTGCCTCGCCAGGCAACAGCGCTCGGCGCCGCTGGAATGGCTGCATTAC
CAACATCAGGGAGGCCTCCCGGCATTGCAAAGCGCTCTGATCCAATATCTGTACCTGACCCGCTCGGTCCGCTGCGAACC
GGAACAAATCATCATCGCCCCAGGCGCCCAAAACGCATTGACGCTGTTGGCCCAGTTGCTGGCCGACCCAGGCGATGCCA
TCTGGCTGGAAGAGCCCGGCTACGCTGGCGCGCAAGCCGCCATGCAGGCCGCCGGCCTCCGCTGCCAAGCCATCCGCGTG
GACGAGCAAGGCTTGCGTCCGGATCCGGAGGCGGCCCCTCCCCGCATCATCTATGTCACGCCGGCCCACCAATATCCGAC
CGGCGCAGTGATGGCGCTGCCGCGCCGGCTGGAACTGCTGGCGCATGCCCGCCGCCACGGCAGTTGGATAATAGAAGACG
ACTACGATGGCGAGTTCTGCTATGCCTCGGCCCCGCTGGCCGCGTTGCAAAGCCTGGATCGGGATGGCCGAGTGATCTAT
CTCGGCACCTTCAGCAAGGTCATGTTCCCCAGCTTGAAGCTTGCCTACCTGGTGCTGCCCCCCGAATTAGTCGATTCTTA
CCGCCGCTGCCAGGCCAGGTTGCAAGGCGAAGGCAGCTATCTGCAACAGGCCGCCGTCGCGGACTTCATCGCGCAGGGGC
ATTTCGCCCGCCATATCCGACACATGCGCGAGCTGTACCAGCGCCGCCAGCAGCTGCTGAAGCATGCGGCAGACCAATAT
CTGGGACACGCCATGTCGCTTCATGGCGGCGACGCCGGCATGCATCTTCTGGCCGAACTGCCGGACGGCTTTGATGAATG
GGAACTGCAGGCTGCCGCAGCCGAGCGCCTGTTGTGGCTCAGGCCGTTGGCCCGCCACTTCCTAGATACCCCATACCGCA
ACGGATTGGTATTGGGTTACGCCGGCATCGACGATCACGCTATCCGCCCAGCCGTGCAACAATTGGCTGACTTGCTGGAA
ACGAGGCTGAAATGA

Upstream 100 bases:

>100_bases
ATCATGGCGCCCACTCCTTGGTTTGTTTGGCAATGCTGGTATGCTAAGCGGAAAGTCATCATGAAAATAGCTCCACTTCT
CTCATTCTGACGGAACCACT

Downstream 100 bases:

>100_bases
AGAAACCGACGCTGTTGGTCAGCGCCTGCCTGCTGGGGCAACCTGTACGCTACGATGGCCAATCCAAACCGCTCTCCAGC
CCGCAATGGGAAGCCCTGAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MDNDWIADYLRPRLARDNGEHLSRQLYRQLRELIGQRRLAGGSVLPASRALAQAMQLGRNTVLSAYDQLAAEGYLESRHG
SGTYVCDVFTNSTSQTSHSTAPARPLSQRGQRLTASSRLPVRKLGAFVPGLPELELFPHKAWQQCLARQQRSAPLEWLHY
QHQGGLPALQSALIQYLYLTRSVRCEPEQIIIAPGAQNALTLLAQLLADPGDAIWLEEPGYAGAQAAMQAAGLRCQAIRV
DEQGLRPDPEAAPPRIIYVTPAHQYPTGAVMALPRRLELLAHARRHGSWIIEDDYDGEFCYASAPLAALQSLDRDGRVIY
LGTFSKVMFPSLKLAYLVLPPELVDSYRRCQARLQGEGSYLQQAAVADFIAQGHFARHIRHMRELYQRRQQLLKHAADQY
LGHAMSLHGGDAGMHLLAELPDGFDEWELQAAAAERLLWLRPLARHFLDTPYRNGLVLGYAGIDDHAIRPAVQQLADLLE
TRLK

Sequences:

>Translated_484_residues
MDNDWIADYLRPRLARDNGEHLSRQLYRQLRELIGQRRLAGGSVLPASRALAQAMQLGRNTVLSAYDQLAAEGYLESRHG
SGTYVCDVFTNSTSQTSHSTAPARPLSQRGQRLTASSRLPVRKLGAFVPGLPELELFPHKAWQQCLARQQRSAPLEWLHY
QHQGGLPALQSALIQYLYLTRSVRCEPEQIIIAPGAQNALTLLAQLLADPGDAIWLEEPGYAGAQAAMQAAGLRCQAIRV
DEQGLRPDPEAAPPRIIYVTPAHQYPTGAVMALPRRLELLAHARRHGSWIIEDDYDGEFCYASAPLAALQSLDRDGRVIY
LGTFSKVMFPSLKLAYLVLPPELVDSYRRCQARLQGEGSYLQQAAVADFIAQGHFARHIRHMRELYQRRQQLLKHAADQY
LGHAMSLHGGDAGMHLLAELPDGFDEWELQAAAAERLLWLRPLARHFLDTPYRNGLVLGYAGIDDHAIRPAVQQLADLLE
TRLK
>Mature_484_residues
MDNDWIADYLRPRLARDNGEHLSRQLYRQLRELIGQRRLAGGSVLPASRALAQAMQLGRNTVLSAYDQLAAEGYLESRHG
SGTYVCDVFTNSTSQTSHSTAPARPLSQRGQRLTASSRLPVRKLGAFVPGLPELELFPHKAWQQCLARQQRSAPLEWLHY
QHQGGLPALQSALIQYLYLTRSVRCEPEQIIIAPGAQNALTLLAQLLADPGDAIWLEEPGYAGAQAAMQAAGLRCQAIRV
DEQGLRPDPEAAPPRIIYVTPAHQYPTGAVMALPRRLELLAHARRHGSWIIEDDYDGEFCYASAPLAALQSLDRDGRVIY
LGTFSKVMFPSLKLAYLVLPPELVDSYRRCQARLQGEGSYLQQAAVADFIAQGHFARHIRHMRELYQRRQQLLKHAADQY
LGHAMSLHGGDAGMHLLAELPDGFDEWELQAAAAERLLWLRPLARHFLDTPYRNGLVLGYAGIDDHAIRPAVQQLADLLE
TRLK

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=398, Percent_Identity=24.6231155778894, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI33469970, Length=398, Percent_Identity=24.6231155778894, Blast_Score=107, Evalue=3e-23,
Organism=Escherichia coli, GI1790797, Length=422, Percent_Identity=26.5402843601896, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787710, Length=475, Percent_Identity=25.0526315789474, Blast_Score=116, Evalue=3e-27,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54039; Mature: 54039

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNDWIADYLRPRLARDNGEHLSRQLYRQLRELIGQRRLAGGSVLPASRALAQAMQLGRN
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHH
TVLSAYDQLAAEGYLESRHGSGTYVCDVFTNSTSQTSHSTAPARPLSQRGQRLTASSRLP
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHCCCEECCCCCCC
VRKLGAFVPGLPELELFPHKAWQQCLARQQRSAPLEWLHYQHQGGLPALQSALIQYLYLT
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
RSVRCEPEQIIIAPGAQNALTLLAQLLADPGDAIWLEEPGYAGAQAAMQAAGLRCQAIRV
HHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCEEEEEEE
DEQGLRPDPEAAPPRIIYVTPAHQYPTGAVMALPRRLELLAHARRHGSWIIEDDYDGEFC
CCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEE
YASAPLAALQSLDRDGRVIYLGTFSKVMFPSLKLAYLVLPPELVDSYRRCQARLQGEGSY
ECCCHHHHHHHCCCCCCEEEEECHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHCCCCHH
LQQAAVADFIAQGHFARHIRHMRELYQRRQQLLKHAADQYLGHAMSLHGGDAGMHLLAEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
PDGFDEWELQAAAAERLLWLRPLARHFLDTPYRNGLVLGYAGIDDHAIRPAVQQLADLLE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
TRLK
HHCC
>Mature Secondary Structure
MDNDWIADYLRPRLARDNGEHLSRQLYRQLRELIGQRRLAGGSVLPASRALAQAMQLGRN
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHH
TVLSAYDQLAAEGYLESRHGSGTYVCDVFTNSTSQTSHSTAPARPLSQRGQRLTASSRLP
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHCCCEECCCCCCC
VRKLGAFVPGLPELELFPHKAWQQCLARQQRSAPLEWLHYQHQGGLPALQSALIQYLYLT
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
RSVRCEPEQIIIAPGAQNALTLLAQLLADPGDAIWLEEPGYAGAQAAMQAAGLRCQAIRV
HHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCEEEEEEE
DEQGLRPDPEAAPPRIIYVTPAHQYPTGAVMALPRRLELLAHARRHGSWIIEDDYDGEFC
CCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEE
YASAPLAALQSLDRDGRVIYLGTFSKVMFPSLKLAYLVLPPELVDSYRRCQARLQGEGSY
ECCCHHHHHHHCCCCCCEEEEECHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHCCCCHH
LQQAAVADFIAQGHFARHIRHMRELYQRRQQLLKHAADQYLGHAMSLHGGDAGMHLLAEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
PDGFDEWELQAAAAERLLWLRPLARHFLDTPYRNGLVLGYAGIDDHAIRPAVQQLADLLE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
TRLK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]