Click here to switch to the map view.

The map label for this gene is recD [H]

Identifier: 34499528

GI number: 34499528

Start: 4405946

End: 4407643

Strand: Reverse

Name: recD [H]

Synonym: CV_4073

Alternate gene names: 34499528

Gene position: 4407643-4405946 (Counterclockwise)

Preceding gene: 34499529

Following gene: 34499527

Centisome position: 92.77

GC content: 73.03

Gene sequence:

>1698_bases
ATGAGAACCGATACCCCGCTGTTGCCCGGCCAACTGGCCCGGCTGTTCCAACGCCTGGCGCCCGACGTCGACGACAGGGT
GCTGGCGCTGATCGGCGAATTGAGCAACGCCAACCTGGCCGGCCATGTCTGTCTGCCGCTGGCGCACCGGGGCGAAGCGG
CGGCGCTGCGCGGCAGTCCGCTGGTCGGCCGGCCGGGCGAGTACGCGCCGCTGATCCTGGACGAGGCCGGGCGGCTGTAC
TTCGCCCGCCATTGGCACGACGAAGACCGGCTGGTCCAGGGGCTGGAGCGATTGGCCCAGCCGCTGCCGCCGCAGGACGA
GGCCAGGCTGGCCGATTGGCTGAATCGCCTGTTTCCCGGCGCGGGCGACGGCGAGCCGGACCGGCAGAAGCTGGCGGCCG
CGCTGGCCGCGCGCCAGCGGCTGATGGTGATCTCCGGCGGACCCGGCACCGGCAAGACCACCACGGTGGTGCGGCTGCTG
GCGCTGCTGGCGGCGATGTCGCCGCGTCCGCTGGTGATGGCGATGGCCGCGCCGACGGGCAAGGCGGCGGCGCGGCTGTC
CGAGTCGGTGCGCGCGGCGCGCGACCGATTGGACGCGGACGACGCGGTGCGCCGCCAGTTGCCGGCGCAGGCGGAGACGC
TGCACCGGCTGCTGGGCCTGCGTCCCGGCGTCGAGGCCCCGCGCCATCACGCAAGCAATCCGCTGCCGCTGGATGTGCTG
GTGGTCGACGAGGCGTCGATGATCGACCTGTCGCTGATGGCGCGCACGGTGGCGGCGCTGCCGTCGCAGGCCCGCTTGAT
CCTGCTGGGCGACCGCGACCAGCTGTCTTCGGTGGAGGCGGGCGCCGTGCTCGGCGAGCTGTGCGGCCGCATCGCCTATC
GCGACGAGACCTCGCAGTGGCTGCAGCGGGTGGCCGGCGCCGTCTTGCAAGGCGATGCCGCGCCCGGCGGCGCGCTGACC
GACTGCGTGGCGTTATTGACGCGCAGCCACCGCTTCGGCGCCGACTCCGGCATCGGCGAGCTGGCGCGTCGGGTCAACGC
CGGCGAAGGGCAGGGTTCGCTGCATGTGCTGGACGACGCCGGCTGGCCCGACGTTTGGCGCCAGGACGCCGCCGACGACG
CCGAGCTGCTCGCGCGCCGGCGCGGCTACCTGGACGCGGTGGCGGCCGGCGCGGGCGCGGACGAGGCGCAGCGCGCGTTT
TCCGCCTTCATGCTGCTGGCCGCCGAGCGGCGCCAGGTGGCTGACTGCAACCGCCGCATCGAGCGGGAGCTGGAGGCCGC
CGGCGTCAAGCAGCCTGGACGTGATTGGTATCCGGGCCGGCCGGTGATGATAGGCGAGAACGATTACGGGCTGGGCCTGT
TCAACGGCGACATCGGCTTCGCCTTGCAGCGGCCGTCAGGCCTGAGGGTGTTGTTTCCGTCCGCCGACGGGGGCTGGCGG
GAGTTCGCGCCCGGACGGCTGCCGGCGCACGAGACGGTGTTCGCGATGACGGTTCACAAGAGCCAGGGCTCGGAGTACGA
CGAAGTGTGGCTGCAATTGCCGCAGCAGGCCGGCGCGCTGCTGAACCGCGCGCTGTTGTATACCGCCATCACCCGCGCCA
AGCTGCGTTTCGCCGCGGTGGGCGACGCCGAAGCATGGCTGCGCGGGGCGGAGCTGGCGCCGCGCCGCGATTCCGGCCTG
GGTGACCGGCTGCATTGA

Upstream 100 bases:

>100_bases
AGGCTGAACCAGGCGATCCAGCAACTGAACGAGCAGGGCCGCTTGCGGCCGCTGTTCGCCCGCCGCTGAGCGCGCCGCCG
TTTTTCCGGAAGTCCCATCG

Downstream 100 bases:

>100_bases
AATCGCGCGGAATGCAACAGTCGTGGGCTTTGTGCGACGAAGGATAGTCAAGCGTCGGCAGACATCCTAATATGCAGCCT
TCCCGGAACCATGCAGGGGG

Product: exodeoxyribonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MRTDTPLLPGQLARLFQRLAPDVDDRVLALIGELSNANLAGHVCLPLAHRGEAAALRGSPLVGRPGEYAPLILDEAGRLY
FARHWHDEDRLVQGLERLAQPLPPQDEARLADWLNRLFPGAGDGEPDRQKLAAALAARQRLMVISGGPGTGKTTTVVRLL
ALLAAMSPRPLVMAMAAPTGKAAARLSESVRAARDRLDADDAVRRQLPAQAETLHRLLGLRPGVEAPRHHASNPLPLDVL
VVDEASMIDLSLMARTVAALPSQARLILLGDRDQLSSVEAGAVLGELCGRIAYRDETSQWLQRVAGAVLQGDAAPGGALT
DCVALLTRSHRFGADSGIGELARRVNAGEGQGSLHVLDDAGWPDVWRQDAADDAELLARRRGYLDAVAAGAGADEAQRAF
SAFMLLAAERRQVADCNRRIERELEAAGVKQPGRDWYPGRPVMIGENDYGLGLFNGDIGFALQRPSGLRVLFPSADGGWR
EFAPGRLPAHETVFAMTVHKSQGSEYDEVWLQLPQQAGALLNRALLYTAITRAKLRFAAVGDAEAWLRGAELAPRRDSGL
GDRLH

Sequences:

>Translated_565_residues
MRTDTPLLPGQLARLFQRLAPDVDDRVLALIGELSNANLAGHVCLPLAHRGEAAALRGSPLVGRPGEYAPLILDEAGRLY
FARHWHDEDRLVQGLERLAQPLPPQDEARLADWLNRLFPGAGDGEPDRQKLAAALAARQRLMVISGGPGTGKTTTVVRLL
ALLAAMSPRPLVMAMAAPTGKAAARLSESVRAARDRLDADDAVRRQLPAQAETLHRLLGLRPGVEAPRHHASNPLPLDVL
VVDEASMIDLSLMARTVAALPSQARLILLGDRDQLSSVEAGAVLGELCGRIAYRDETSQWLQRVAGAVLQGDAAPGGALT
DCVALLTRSHRFGADSGIGELARRVNAGEGQGSLHVLDDAGWPDVWRQDAADDAELLARRRGYLDAVAAGAGADEAQRAF
SAFMLLAAERRQVADCNRRIERELEAAGVKQPGRDWYPGRPVMIGENDYGLGLFNGDIGFALQRPSGLRVLFPSADGGWR
EFAPGRLPAHETVFAMTVHKSQGSEYDEVWLQLPQQAGALLNRALLYTAITRAKLRFAAVGDAEAWLRGAELAPRRDSGL
GDRLH
>Mature_565_residues
MRTDTPLLPGQLARLFQRLAPDVDDRVLALIGELSNANLAGHVCLPLAHRGEAAALRGSPLVGRPGEYAPLILDEAGRLY
FARHWHDEDRLVQGLERLAQPLPPQDEARLADWLNRLFPGAGDGEPDRQKLAAALAARQRLMVISGGPGTGKTTTVVRLL
ALLAAMSPRPLVMAMAAPTGKAAARLSESVRAARDRLDADDAVRRQLPAQAETLHRLLGLRPGVEAPRHHASNPLPLDVL
VVDEASMIDLSLMARTVAALPSQARLILLGDRDQLSSVEAGAVLGELCGRIAYRDETSQWLQRVAGAVLQGDAAPGGALT
DCVALLTRSHRFGADSGIGELARRVNAGEGQGSLHVLDDAGWPDVWRQDAADDAELLARRRGYLDAVAAGAGADEAQRAF
SAFMLLAAERRQVADCNRRIERELEAAGVKQPGRDWYPGRPVMIGENDYGLGLFNGDIGFALQRPSGLRVLFPSADGGWR
EFAPGRLPAHETVFAMTVHKSQGSEYDEVWLQLPQQAGALLNRALLYTAITRAKLRFAAVGDAEAWLRGAELAPRRDSGL
GDRLH

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=566, Percent_Identity=43.6395759717314, Blast_Score=348, Evalue=6e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 60855; Mature: 60855

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTDTPLLPGQLARLFQRLAPDVDDRVLALIGELSNANLAGHVCLPLAHRGEAAALRGSP
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEECCCC
LVGRPGEYAPLILDEAGRLYFARHWHDEDRLVQGLERLAQPLPPQDEARLADWLNRLFPG
CCCCCCCCCCEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
AGDGEPDRQKLAAALAARQRLMVISGGPGTGKTTTVVRLLALLAAMSPRPLVMAMAAPTG
CCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCC
KAAARLSESVRAARDRLDADDAVRRQLPAQAETLHRLLGLRPGVEAPRHHASNPLPLDVL
HHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHCCCCCCCEEEE
VVDEASMIDLSLMARTVAALPSQARLILLGDRDQLSSVEAGAVLGELCGRIAYRDETSQW
EECCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LQRVAGAVLQGDAAPGGALTDCVALLTRSHRFGADSGIGELARRVNAGEGQGSLHVLDDA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCEEEECCC
GWPDVWRQDAADDAELLARRRGYLDAVAAGAGADEAQRAFSAFMLLAAERRQVADCNRRI
CCCHHHHHCCCCHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERELEAAGVKQPGRDWYPGRPVMIGENDYGLGLFNGDIGFALQRPSGLRVLFPSADGGWR
HHHHHHCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCEEEECCCCCEEEEECCCCCHH
EFAPGRLPAHETVFAMTVHKSQGSEYDEVWLQLPQQAGALLNRALLYTAITRAKLRFAAV
HCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
GDAEAWLRGAELAPRRDSGLGDRLH
CCHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRTDTPLLPGQLARLFQRLAPDVDDRVLALIGELSNANLAGHVCLPLAHRGEAAALRGSP
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEECCCC
LVGRPGEYAPLILDEAGRLYFARHWHDEDRLVQGLERLAQPLPPQDEARLADWLNRLFPG
CCCCCCCCCCEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
AGDGEPDRQKLAAALAARQRLMVISGGPGTGKTTTVVRLLALLAAMSPRPLVMAMAAPTG
CCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCC
KAAARLSESVRAARDRLDADDAVRRQLPAQAETLHRLLGLRPGVEAPRHHASNPLPLDVL
HHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHCCCCCCCEEEE
VVDEASMIDLSLMARTVAALPSQARLILLGDRDQLSSVEAGAVLGELCGRIAYRDETSQW
EECCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LQRVAGAVLQGDAAPGGALTDCVALLTRSHRFGADSGIGELARRVNAGEGQGSLHVLDDA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCEEEECCC
GWPDVWRQDAADDAELLARRRGYLDAVAAGAGADEAQRAFSAFMLLAAERRQVADCNRRI
CCCHHHHHCCCCHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERELEAAGVKQPGRDWYPGRPVMIGENDYGLGLFNGDIGFALQRPSGLRVLFPSADGGWR
HHHHHHCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCCEEEECCCCCEEEEECCCCCHH
EFAPGRLPAHETVFAMTVHKSQGSEYDEVWLQLPQQAGALLNRALLYTAITRAKLRFAAV
HCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
GDAEAWLRGAELAPRRDSGLGDRLH
CCHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]