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The map label for this gene is rfbC [H]

Identifier: 34499468

GI number: 34499468

Start: 4339325

End: 4339867

Strand: Direct

Name: rfbC [H]

Synonym: CV_4013

Alternate gene names: 34499468

Gene position: 4339325-4339867 (Clockwise)

Preceding gene: 34499467

Following gene: 34499472

Centisome position: 91.33

GC content: 61.69

Gene sequence:

>543_bases
ATGAAAGTCATTGATACCGAGATCTCCGCGGTCAAGATCATCGAGCCCCAGATATTTGGCGATGAGCGCGGTTTTTTCTT
CGAAAGCTTCAATCAGCAGCGTTTCGAACAGGCTGTCGGCCATGCGGTCGACTTCGTGCAGGACAACCACAGCCGCTCCG
GCAAAAATGTCCTGCGCGGGCTGCACTACCAGCTCGATCCGCATCCGCAGGGAAAGCTGGTGCGCGTCGTGTCAGGCGCA
GTATTCGACGTCGCAGTCGACATCCGTCCCGGTTCCGAGACCTTCGGCCAATGGGTCGGAGTAGAGCTCAGCGCCGCCAA
CAAGCGTCAGCTGTGGATTCCCGCCGGCTTCGCCCACGGCTTCCTCACGCTGAGCGACGATGTGGAGTTCCTGTACAAGA
CCACCGATTACTGGCATCCGGAGCTGGAACGCACCCTCGCCTGGGATGACCCGGACCTGGCAATCGCCTGGCCGCTGAGC
GACGCGCCGACGCTGTCAGCCAAGGACCAGACCGGCGCCTCCTTCTCCTCGCTGCCGCGCTGA

Upstream 100 bases:

>100_bases
ACGCCAGCTGGCCCAGCCCTTGCAGAAAACCGGCTACGGCCGCTATCTGCTGGCGATGCTCAGCAACTGACACCCTACAC
GAACAGAACAAAGACAAGCG

Downstream 100 bases:

>100_bases
AGCCATTTCTGAAATGCAAACAGCCCCGCAGGCATAAGCCGCGGGGCTGTTTGTTTGGGCAGGCATGCGAACATGCCCGC
CTGACCGGCTCGATTTACAT

Product: dTDP-6-deoxy-D-glucose-3,5 epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MKVIDTEISAVKIIEPQIFGDERGFFFESFNQQRFEQAVGHAVDFVQDNHSRSGKNVLRGLHYQLDPHPQGKLVRVVSGA
VFDVAVDIRPGSETFGQWVGVELSAANKRQLWIPAGFAHGFLTLSDDVEFLYKTTDYWHPELERTLAWDDPDLAIAWPLS
DAPTLSAKDQTGASFSSLPR

Sequences:

>Translated_180_residues
MKVIDTEISAVKIIEPQIFGDERGFFFESFNQQRFEQAVGHAVDFVQDNHSRSGKNVLRGLHYQLDPHPQGKLVRVVSGA
VFDVAVDIRPGSETFGQWVGVELSAANKRQLWIPAGFAHGFLTLSDDVEFLYKTTDYWHPELERTLAWDDPDLAIAWPLS
DAPTLSAKDQTGASFSSLPR
>Mature_180_residues
MKVIDTEISAVKIIEPQIFGDERGFFFESFNQQRFEQAVGHAVDFVQDNHSRSGKNVLRGLHYQLDPHPQGKLVRVVSGA
VFDVAVDIRPGSETFGQWVGVELSAANKRQLWIPAGFAHGFLTLSDDVEFLYKTTDYWHPELERTLAWDDPDLAIAWPLS
DAPTLSAKDQTGASFSSLPR

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=180, Percent_Identity=61.1111111111111, Blast_Score=227, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17550412, Length=174, Percent_Identity=47.1264367816092, Blast_Score=147, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20174; Mature: 20174

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIDTEISAVKIIEPQIFGDERGFFFESFNQQRFEQAVGHAVDFVQDNHSRSGKNVLRG
CEEECCCCCEEEEECCEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHC
LHYQLDPHPQGKLVRVVSGAVFDVAVDIRPGSETFGQWVGVELSAANKRQLWIPAGFAHG
CCEECCCCCCCCEEEEECCEEEEEEEEECCCHHHHHHEECEEEECCCCEEEEEECCCCCC
FLTLSDDVEFLYKTTDYWHPELERTLAWDDPDLAIAWPLSDAPTLSAKDQTGASFSSLPR
EEEECCCCEEEEECCCCCCCCHHHEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKVIDTEISAVKIIEPQIFGDERGFFFESFNQQRFEQAVGHAVDFVQDNHSRSGKNVLRG
CEEECCCCCEEEEECCEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHC
LHYQLDPHPQGKLVRVVSGAVFDVAVDIRPGSETFGQWVGVELSAANKRQLWIPAGFAHG
CCEECCCCCCCCEEEEECCEEEEEEEEECCCHHHHHHEECEEEECCCCEEEEEECCCCCC
FLTLSDDVEFLYKTTDYWHPELERTLAWDDPDLAIAWPLSDAPTLSAKDQTGASFSSLPR
EEEECCCCEEEEECCCCCCCCHHHEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]