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The map label for this gene is argB

Identifier: 34499376

GI number: 34499376

Start: 4233891

End: 4234760

Strand: Reverse

Name: argB

Synonym: CV_3921

Alternate gene names: 34499376

Gene position: 4234760-4233891 (Counterclockwise)

Preceding gene: 34499387

Following gene: 34499375

Centisome position: 89.13

GC content: 65.52

Gene sequence:

>870_bases
GTGGCAACAGACGCAGCCGAAAAGGCGAACATCCTGGCCGAGGCCTTGCCGTACATCCGCGAATTCGCGGGCAAGACCAT
CGTGATCAAGTACGGCGGCAACGCGATGACCGACGACGCGCTGAAAGAGGGCTTCGCCAAGGACGTGGTGTTGCTGAAGC
TGGTGGGGATGAACCCGGTGGTGGTGCATGGCGGCGGCCCGCAAATCAACGACCTGCTGGCGCGCGTCGGCAAGCAGGGC
GAGTTTATCCAGGGCATGCGCGTCACCGACGCCGAGACCATGGAAGTGGTGGAAATGGTGCTGGGCGGCCTGGTGAACAA
GGAGATCGTGTCGCTGATCAACAAGCACGGCGGCAAGGCGGTGGGCCTGACCGGCAAGGACGGCCATTTCATCCGCGCCC
GCAAGCTGTTCCTCAAGACCGACGGCGACGAGGACGTCGATATCGGGCAGGTCGGCGAGATCGAGGCCATCGATCCGGCG
CTGGTGTCGCTGCTGGACAGCCAGGATTTCATCCCGGTGGTGGCGCCGATCGGCGTCGGCGTGGATGGCGAAGCCTACAA
CATCAACGCCGACCTGGTGGCCGGCAAGCTGGCCGAGACGCTGCGGGCGGAAAAGCTGGTGCTGATGACCAATACCCCGG
GCGTGCTGGACAAGCAGGGCCAGCTGCTGACCGGACTGACCGCGCAGCGCATCGACGAGCTGTTCGCCGACGGCACCATC
TCCGGCGGCATGCTGCCCAAGATCAGCTCCGCGCTGGACGCCGCCAGGAACGGCGTCAACTCGGTCCACGTCATCGACGG
CCGGGTCAAGCACGCGTTGCTGCTGGAAATCCTGACCGCGGCCGGCGTCGGCACCATGATCCGCGCCTGA

Upstream 100 bases:

>100_bases
AGTTCAGTAATTGATGTGATTAAAATGCAACACCGTAATCCGAAATCGCCGGCCTGCCGTCATGGCTGGCAAAAGCGATC
CGCCAGCAAGGAGAAATGAA

Downstream 100 bases:

>100_bases
GCCGGGACCGTCCGGCGGACGTGGAGCCGCGGGCGGCGGTGGGCTATAGTGATGTCATGCCGCGCGCCTTGGCGCCGCGG
GTCACAAGGGGAGGCAGCAT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MATDAAEKANILAEALPYIREFAGKTIVIKYGGNAMTDDALKEGFAKDVVLLKLVGMNPVVVHGGGPQINDLLARVGKQG
EFIQGMRVTDAETMEVVEMVLGGLVNKEIVSLINKHGGKAVGLTGKDGHFIRARKLFLKTDGDEDVDIGQVGEIEAIDPA
LVSLLDSQDFIPVVAPIGVGVDGEAYNINADLVAGKLAETLRAEKLVLMTNTPGVLDKQGQLLTGLTAQRIDELFADGTI
SGGMLPKISSALDAARNGVNSVHVIDGRVKHALLLEILTAAGVGTMIRA

Sequences:

>Translated_289_residues
MATDAAEKANILAEALPYIREFAGKTIVIKYGGNAMTDDALKEGFAKDVVLLKLVGMNPVVVHGGGPQINDLLARVGKQG
EFIQGMRVTDAETMEVVEMVLGGLVNKEIVSLINKHGGKAVGLTGKDGHFIRARKLFLKTDGDEDVDIGQVGEIEAIDPA
LVSLLDSQDFIPVVAPIGVGVDGEAYNINADLVAGKLAETLRAEKLVLMTNTPGVLDKQGQLLTGLTAQRIDELFADGTI
SGGMLPKISSALDAARNGVNSVHVIDGRVKHALLLEILTAAGVGTMIRA
>Mature_288_residues
ATDAAEKANILAEALPYIREFAGKTIVIKYGGNAMTDDALKEGFAKDVVLLKLVGMNPVVVHGGGPQINDLLARVGKQGE
FIQGMRVTDAETMEVVEMVLGGLVNKEIVSLINKHGGKAVGLTGKDGHFIRARKLFLKTDGDEDVDIGQVGEIEAIDPAL
VSLLDSQDFIPVVAPIGVGVDGEAYNINADLVAGKLAETLRAEKLVLMTNTPGVLDKQGQLLTGLTAQRIDELFADGTIS
GGMLPKISSALDAARNGVNSVHVIDGRVKHALLLEILTAAGVGTMIRA

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=284, Percent_Identity=30.9859154929577, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI145693208, Length=243, Percent_Identity=32.9218106995885, Blast_Score=105, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6320913, Length=287, Percent_Identity=27.8745644599303, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_CHRVO (Q7NR63)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903591.1
- ProteinModelPortal:   Q7NR63
- SMR:   Q7NR63
- GeneID:   2547773
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3921
- NMPDR:   fig|243365.1.peg.3921
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   Q7NR63
- ProtClustDB:   PRK00942
- BioCyc:   CVIO243365:CV_3921-MONOMER
- BRENDA:   2.7.2.8
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 30354; Mature: 30222

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: BINDING 87-87 BINDING 187-187

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATDAAEKANILAEALPYIREFAGKTIVIKYGGNAMTDDALKEGFAKDVVLLKLVGMNPV
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHEEEEEEECCCEE
VVHGGGPQINDLLARVGKQGEFIQGMRVTDAETMEVVEMVLGGLVNKEIVSLINKHGGKA
EEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCE
VGLTGKDGHFIRARKLFLKTDGDEDVDIGQVGEIEAIDPALVSLLDSQDFIPVVAPIGVG
EEECCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCC
VDGEAYNINADLVAGKLAETLRAEKLVLMTNTPGVLDKQGQLLTGLTAQRIDELFADGTI
CCCCEEECCHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
SGGMLPKISSALDAARNGVNSVHVIDGRVKHALLLEILTAAGVGTMIRA
CCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure 
ATDAAEKANILAEALPYIREFAGKTIVIKYGGNAMTDDALKEGFAKDVVLLKLVGMNPV
CCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHEEEEEEECCCEE
VVHGGGPQINDLLARVGKQGEFIQGMRVTDAETMEVVEMVLGGLVNKEIVSLINKHGGKA
EEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCE
VGLTGKDGHFIRARKLFLKTDGDEDVDIGQVGEIEAIDPALVSLLDSQDFIPVVAPIGVG
EEECCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCC
VDGEAYNINADLVAGKLAETLRAEKLVLMTNTPGVLDKQGQLLTGLTAQRIDELFADGTI
CCCCEEECCHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
SGGMLPKISSALDAARNGVNSVHVIDGRVKHALLLEILTAAGVGTMIRA
CCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782