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The map label for this gene is etfD [H]

Identifier: 34499371

GI number: 34499371

Start: 4228074

End: 4229693

Strand: Reverse

Name: etfD [H]

Synonym: CV_3916

Alternate gene names: 34499371

Gene position: 4229693-4228074 (Counterclockwise)

Preceding gene: 34499372

Following gene: 34499370

Centisome position: 89.03

GC content: 65.8

Gene sequence:

>1620_bases
ATGGAATACGACGTGGTGATCGTCGGCGGCGGTCCTTCCGGCCTGTCCGCGGCGATCCGTTTGAAACAGCTGGCGGCCGA
GCAGGGCCGCGACATCAGCGTGTGCCTGCTGGAGAAGGGCTCAGAGATCGGCGCCCACATCCTGTCCGGCGCGGTGATCG
AAACCGGCGCGCTGGCCGAGTTGCTGCCCAACTGGAAAGAGCTGGACGCGCCGCTGAACACGCCGGCGCTGTCCGACCGC
TTCCTCTATCTGACCGAGACCGAGTCCATCCAGCTGCCCACCCCGCCGCAGATGCACAACCAGGGCAACTACATCGTCAG
CCTGGGCAACTTCTGCCGCTGGCTGGCGCAGCAGGCCGAGAACCTGGGCGTGGAGATCTACCCGGGCTTCGCCGCCGCCG
AGGTGCTGTACCACGCGGACGGCTCGGTCAAGGGCGTGGCCACCGGCAATGTCGGCACCGGCAAGAACGGCGACCAGGAA
GGCGAGCCGGGCATGGAGCTGTGGGCGAAGCAGACCATCTTCGCCGAAGGCTGTAGGGGCTCGCTGACCAAGGGGCTGCT
GTCGCGCTTCCGCCTGACCGACGGCTCGGATCCGCAGACCTTCGGCATCGGCATCAAGGAATTGTGGGAAGTGAAGCCGG
AAAACCACCAGCCCGGCCACATCACCCACACCGTGGGTTGGCCGATGGACACCGCCACCTACGGCGGTTCCTTCCTTTAC
CACCTGGAAGACAATCTGGTGGCTGTCGGCTTCGTGGTCGGCCTGGATTATAAAAATCCCTATCTGTCGCCGTTCGAGGA
GTTCCAGCGCTTCAAGACCCATCCGGCGATCAAGAAGACCTTCGAAGGCGGCCGCCGCGTGTCCTACGGCGCGCGCGCGC
TGGCCGAGGGCGGCCTGCAAAGCCTGCCCAAGCTGACCTTCCCCGGCGGCGTGCTGGTCGGCGACACCGCCGGCTTCCTC
AACGTGCCCAAGATCAAGGGCACCCATACCGCGATGAAGTCGGCCATGCTGGCGGCGGAGGCGGTGTTCGAGCTGCTGGG
CGACGACGCGCAGGCGCAGGGCGGCGAGGCCAAGTCCTACTCGGCCAAGTTCCAGCAGAGCTGGGTACGCGACGAGCTGC
ACAAGGTGCGCAATATCCGCCCATCGTTCCGCTGGGGCCTGTGGCCGGCGATGATCTACTCGGCCATCGACACCTTCCTG
TTCCGCGGCCGCGCGCCGTGGACGCTGCATCACCAGCACGCCGACAACGAGGCGCTGCGTCCTGCCTACGAATTCAGCCC
CATCGCCTATCCCAAGCCGGACGGGGTGCTGACCTTCGACCGCCTGTCGTCGGTGTTCATTTCCAACGCCAACCATAGCG
AAGACCAGCCGGCCCATCTGAAGCTGAAGGACGCGTCGGTGCCGATCGCAGTCAACCTGGCCAAGTACGACGCCCCCGAG
CAGCGCTACTGCCCGGCCGGCGTCTACGAGATCGTCGGCCAGGACGAAGGCGCGCCGCGGCTGCAGATCAACGCGCAGAA
CTGCGTGCACTGCAAGACCTGCGACATCAAGGATCCGACCCAGAACATCAACTGGGTGACGCCGGAAGGCGGCGGCGGGC
CGAATTATCCCAACATGTGA

Upstream 100 bases:

>100_bases
GCTTGTTTGATTTTGACGACGTGACATCTTCATAGCATGATGTCCGGAAAATCAAACCCGTCCCAGCGGGCGCAAAGGAG
AAACGGTGCAACGCGAATAC

Downstream 100 bases:

>100_bases
TCGAACGGCGCATGCCGCGCGAGGCCGGGTTTCCTGTCGGAAATCCGGTCTTTTTTCTTGATGGCGGCCAAGTCTTGGGA
AACAACGGCTTGACGGCGGC

Product: electron-transferring-flavoprotein dehydrogenase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MEYDVVIVGGGPSGLSAAIRLKQLAAEQGRDISVCLLEKGSEIGAHILSGAVIETGALAELLPNWKELDAPLNTPALSDR
FLYLTETESIQLPTPPQMHNQGNYIVSLGNFCRWLAQQAENLGVEIYPGFAAAEVLYHADGSVKGVATGNVGTGKNGDQE
GEPGMELWAKQTIFAEGCRGSLTKGLLSRFRLTDGSDPQTFGIGIKELWEVKPENHQPGHITHTVGWPMDTATYGGSFLY
HLEDNLVAVGFVVGLDYKNPYLSPFEEFQRFKTHPAIKKTFEGGRRVSYGARALAEGGLQSLPKLTFPGGVLVGDTAGFL
NVPKIKGTHTAMKSAMLAAEAVFELLGDDAQAQGGEAKSYSAKFQQSWVRDELHKVRNIRPSFRWGLWPAMIYSAIDTFL
FRGRAPWTLHHQHADNEALRPAYEFSPIAYPKPDGVLTFDRLSSVFISNANHSEDQPAHLKLKDASVPIAVNLAKYDAPE
QRYCPAGVYEIVGQDEGAPRLQINAQNCVHCKTCDIKDPTQNINWVTPEGGGGPNYPNM

Sequences:

>Translated_539_residues
MEYDVVIVGGGPSGLSAAIRLKQLAAEQGRDISVCLLEKGSEIGAHILSGAVIETGALAELLPNWKELDAPLNTPALSDR
FLYLTETESIQLPTPPQMHNQGNYIVSLGNFCRWLAQQAENLGVEIYPGFAAAEVLYHADGSVKGVATGNVGTGKNGDQE
GEPGMELWAKQTIFAEGCRGSLTKGLLSRFRLTDGSDPQTFGIGIKELWEVKPENHQPGHITHTVGWPMDTATYGGSFLY
HLEDNLVAVGFVVGLDYKNPYLSPFEEFQRFKTHPAIKKTFEGGRRVSYGARALAEGGLQSLPKLTFPGGVLVGDTAGFL
NVPKIKGTHTAMKSAMLAAEAVFELLGDDAQAQGGEAKSYSAKFQQSWVRDELHKVRNIRPSFRWGLWPAMIYSAIDTFL
FRGRAPWTLHHQHADNEALRPAYEFSPIAYPKPDGVLTFDRLSSVFISNANHSEDQPAHLKLKDASVPIAVNLAKYDAPE
QRYCPAGVYEIVGQDEGAPRLQINAQNCVHCKTCDIKDPTQNINWVTPEGGGGPNYPNM
>Mature_539_residues
MEYDVVIVGGGPSGLSAAIRLKQLAAEQGRDISVCLLEKGSEIGAHILSGAVIETGALAELLPNWKELDAPLNTPALSDR
FLYLTETESIQLPTPPQMHNQGNYIVSLGNFCRWLAQQAENLGVEIYPGFAAAEVLYHADGSVKGVATGNVGTGKNGDQE
GEPGMELWAKQTIFAEGCRGSLTKGLLSRFRLTDGSDPQTFGIGIKELWEVKPENHQPGHITHTVGWPMDTATYGGSFLY
HLEDNLVAVGFVVGLDYKNPYLSPFEEFQRFKTHPAIKKTFEGGRRVSYGARALAEGGLQSLPKLTFPGGVLVGDTAGFL
NVPKIKGTHTAMKSAMLAAEAVFELLGDDAQAQGGEAKSYSAKFQQSWVRDELHKVRNIRPSFRWGLWPAMIYSAIDTFL
FRGRAPWTLHHQHADNEALRPAYEFSPIAYPKPDGVLTFDRLSSVFISNANHSEDQPAHLKLKDASVPIAVNLAKYDAPE
QRYCPAGVYEIVGQDEGAPRLQINAQNCVHCKTCDIKDPTQNINWVTPEGGGGPNYPNM

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=550, Percent_Identity=60, Blast_Score=664, Evalue=0.0,
Organism=Escherichia coli, GI1787991, Length=392, Percent_Identity=28.0612244897959, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786227, Length=335, Percent_Identity=28.955223880597, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI87082155, Length=388, Percent_Identity=27.8350515463918, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25144720, Length=551, Percent_Identity=58.0762250453721, Blast_Score=628, Evalue=1e-180,
Organism=Saccharomyces cerevisiae, GI6324932, Length=566, Percent_Identity=49.1166077738516, Blast_Score=536, Evalue=1e-153,
Organism=Drosophila melanogaster, GI24652256, Length=549, Percent_Identity=59.5628415300546, Blast_Score=660, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 58776; Mature: 58776

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYDVVIVGGGPSGLSAAIRLKQLAAEQGRDISVCLLEKGSEIGAHILSGAVIETGALAE
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCHHCCCHHHH
LLPNWKELDAPLNTPALSDRFLYLTETESIQLPTPPQMHNQGNYIVSLGNFCRWLAQQAE
HCCCHHHHCCCCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCEEEEHHHHHHHHHHHHH
NLGVEIYPGFAAAEVLYHADGSVKGVATGNVGTGKNGDQEGEPGMELWAKQTIFAEGCRG
HCCEEEECCHHHHHHEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
SLTKGLLSRFRLTDGSDPQTFGIGIKELWEVKPENHQPGHITHTVGWPMDTATYGGSFLY
HHHHHHHHHHCCCCCCCCCEECCCHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCEEEE
HLEDNLVAVGFVVGLDYKNPYLSPFEEFQRFKTHPAIKKTFEGGRRVSYGARALAEGGLQ
EECCCEEEEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHCCCCEECHHHHHHHHCCHH
SLPKLTFPGGVLVGDTAGFLNVPKIKGTHTAMKSAMLAAEAVFELLGDDAQAQGGEAKSY
HCCCCCCCCCEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
SAKFQQSWVRDELHKVRNIRPSFRWGLWPAMIYSAIDTFLFRGRAPWTLHHQHADNEALR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
PAYEFSPIAYPKPDGVLTFDRLSSVFISNANHSEDQPAHLKLKDASVPIAVNLAKYDAPE
CCCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEHHCCCCC
QRYCPAGVYEIVGQDEGAPRLQINAQNCVHCKTCDIKDPTQNINWVTPEGGGGPNYPNM
CCCCCCCHHHHHCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCC
>Mature Secondary Structure
MEYDVVIVGGGPSGLSAAIRLKQLAAEQGRDISVCLLEKGSEIGAHILSGAVIETGALAE
CCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCHHCCCHHHH
LLPNWKELDAPLNTPALSDRFLYLTETESIQLPTPPQMHNQGNYIVSLGNFCRWLAQQAE
HCCCHHHHCCCCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCEEEEHHHHHHHHHHHHH
NLGVEIYPGFAAAEVLYHADGSVKGVATGNVGTGKNGDQEGEPGMELWAKQTIFAEGCRG
HCCEEEECCHHHHHHEEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
SLTKGLLSRFRLTDGSDPQTFGIGIKELWEVKPENHQPGHITHTVGWPMDTATYGGSFLY
HHHHHHHHHHCCCCCCCCCEECCCHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCEEEE
HLEDNLVAVGFVVGLDYKNPYLSPFEEFQRFKTHPAIKKTFEGGRRVSYGARALAEGGLQ
EECCCEEEEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHCCCCEECHHHHHHHHCCHH
SLPKLTFPGGVLVGDTAGFLNVPKIKGTHTAMKSAMLAAEAVFELLGDDAQAQGGEAKSY
HCCCCCCCCCEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
SAKFQQSWVRDELHKVRNIRPSFRWGLWPAMIYSAIDTFLFRGRAPWTLHHQHADNEALR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
PAYEFSPIAYPKPDGVLTFDRLSSVFISNANHSEDQPAHLKLKDASVPIAVNLAKYDAPE
CCCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEHHCCCCC
QRYCPAGVYEIVGQDEGAPRLQINAQNCVHCKTCDIKDPTQNINWVTPEGGGGPNYPNM
CCCCCCCHHHHHCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]