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The map label for this gene is galU [H]

Identifier: 34499356

GI number: 34499356

Start: 4210760

End: 4211632

Strand: Reverse

Name: galU [H]

Synonym: CV_3901

Alternate gene names: 34499356

Gene position: 4211632-4210760 (Counterclockwise)

Preceding gene: 34499357

Following gene: 34499355

Centisome position: 88.65

GC content: 63.0

Gene sequence:

>873_bases
ATGAAGAAAATCACCAAAGCGGTATTTCCGGTGGCCGGTCTGGGCACCCGTTTCCTGCCCGCCACCAAGGCCAGTCCCAA
GGAGATGCTGCCCGTCGTCGACAAGCCGCTGATCCAGTACGCGGTGGAGGAGGCGATCGCCGCCGGCATGACCGAGCTGA
TCTTCATCACCGGCCGCAACAAGCGTTCGATCGAGGACCATTTCGACAAAGCCTACGAGCTGGAGACCGAGCTCGAATAC
AAGAACAAGCAGAAGCTGCTGCAGCTGGTGCAGGAAATCATTCCGCCTTCTGTCAGCTGCATCTATATCCGCCAGACCGA
GGCGCTGGGCCTGGGCCATGCCGTGCTGTGCGCGCGCCCGGTGGTGGGAGACGAGCCGTTTGCGGTGATTCTGGCCGACG
ATTTGATCGAAGGCGCGCCGGGCGCGATGGAGCAGATGGTGCGCCTGTTCGACGAGACCCACTCGTCCATCCTGGGCGTG
GAGACCGTGGCGCCGGAAGAGACCGGCTCCTATGGCATCGTCAAGGTGGCCGCAAATGCGCAAGGCCATCAGCGCGTAGA
GCACATCGTGGAGAAGCCGCGCCCGGAAGAGGCGCCGTCCAATCTGGCCGTGGTCGGCCGCTATATCCTGACCCCGCGCA
TCTTCGACAAGCTGGTCAACACCGCAGCCGGCGCCGGCGGCGAAATCCAGCTGACCGACGGCATCGCCGCGCTGATGAAG
AACGAGCCGGTGCTGGCCTTGCCCTTCAAGGGCACCCGCTACGATTGCGGCTCCAAGCTGGGCTATCTGAAGGCCACGGT
CAACTATGGTTTGAAGCACAATGAGGTGGCCGGCGATTTCGCCGCCTTCCTGCGCGAGCTGAAGCTCGACTGA

Upstream 100 bases:

>100_bases
GAGGCGCTGGCTGGACGACAGACATTTTGACCTTGAGCGAAGTCGGGCTAGAATGCGGCGCTGTTATCTAGCCTGATCGA
CATGGATTGCGGAGTTTGAG

Downstream 100 bases:

>100_bases
CCGTTTTTCCCATTGCGCCGCCCGCGGGCGGCGCCGCCTGTTCTGTTCAAGGAGTCATCATGCCTAATATTGCCGAAGCC
CGCGGTCTGATCAACAGCTC

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MKKITKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGMTELIFITGRNKRSIEDHFDKAYELETELEY
KNKQKLLQLVQEIIPPSVSCIYIRQTEALGLGHAVLCARPVVGDEPFAVILADDLIEGAPGAMEQMVRLFDETHSSILGV
ETVAPEETGSYGIVKVAANAQGHQRVEHIVEKPRPEEAPSNLAVVGRYILTPRIFDKLVNTAAGAGGEIQLTDGIAALMK
NEPVLALPFKGTRYDCGSKLGYLKATVNYGLKHNEVAGDFAAFLRELKLD

Sequences:

>Translated_290_residues
MKKITKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGMTELIFITGRNKRSIEDHFDKAYELETELEY
KNKQKLLQLVQEIIPPSVSCIYIRQTEALGLGHAVLCARPVVGDEPFAVILADDLIEGAPGAMEQMVRLFDETHSSILGV
ETVAPEETGSYGIVKVAANAQGHQRVEHIVEKPRPEEAPSNLAVVGRYILTPRIFDKLVNTAAGAGGEIQLTDGIAALMK
NEPVLALPFKGTRYDCGSKLGYLKATVNYGLKHNEVAGDFAAFLRELKLD
>Mature_290_residues
MKKITKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGMTELIFITGRNKRSIEDHFDKAYELETELEY
KNKQKLLQLVQEIIPPSVSCIYIRQTEALGLGHAVLCARPVVGDEPFAVILADDLIEGAPGAMEQMVRLFDETHSSILGV
ETVAPEETGSYGIVKVAANAQGHQRVEHIVEKPRPEEAPSNLAVVGRYILTPRIFDKLVNTAAGAGGEIQLTDGIAALMK
NEPVLALPFKGTRYDCGSKLGYLKATVNYGLKHNEVAGDFAAFLRELKLD

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. a glycolipid found in the membrane, which is also used as a membrane anchor for lipote

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=292, Percent_Identity=53.0821917808219, Blast_Score=285, Evalue=2e-78,
Organism=Escherichia coli, GI1788355, Length=291, Percent_Identity=44.3298969072165, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1788351, Length=234, Percent_Identity=25.6410256410256, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790224, Length=228, Percent_Identity=24.5614035087719, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 31582; Mature: 31582

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKITKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGMTELIFITGRN
CCCHHHHHCCHHCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEECCC
KRSIEDHFDKAYELETELEYKNKQKLLQLVQEIIPPSVSCIYIRQTEALGLGHAVLCARP
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHCCC
VVGDEPFAVILADDLIEGAPGAMEQMVRLFDETHSSILGVETVAPEETGSYGIVKVAANA
CCCCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCEEEEEECCC
QGHQRVEHIVEKPRPEEAPSNLAVVGRYILTPRIFDKLVNTAAGAGGEIQLTDGIAALMK
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEHHHHHHHHC
NEPVLALPFKGTRYDCGSKLGYLKATVNYGLKHNEVAGDFAAFLRELKLD
CCCEEEECCCCCCCCCCCCCHHEEEHHHCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKITKAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGMTELIFITGRN
CCCHHHHHCCHHCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEECCC
KRSIEDHFDKAYELETELEYKNKQKLLQLVQEIIPPSVSCIYIRQTEALGLGHAVLCARP
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHCCC
VVGDEPFAVILADDLIEGAPGAMEQMVRLFDETHSSILGVETVAPEETGSYGIVKVAANA
CCCCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCEEEEEECCC
QGHQRVEHIVEKPRPEEAPSNLAVVGRYILTPRIFDKLVNTAAGAGGEIQLTDGIAALMK
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEHHHHHHHHC
NEPVLALPFKGTRYDCGSKLGYLKATVNYGLKHNEVAGDFAAFLRELKLD
CCCEEEECCCCCCCCCCCCCHHEEEHHHCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA