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The map label for this gene is lldR [H]

Identifier: 34499185

GI number: 34499185

Start: 4027515

End: 4028204

Strand: Direct

Name: lldR [H]

Synonym: CV_3730

Alternate gene names: 34499185

Gene position: 4027515-4028204 (Clockwise)

Preceding gene: 34499184

Following gene: 34499186

Centisome position: 84.77

GC content: 71.45

Gene sequence:

>690_bases
ATGAATATTTCCTCCTCCAAGCGCTCGCTGGTCGACATCGCCGTCGACAATCTGGGCAAACAGCTGGAACAGGGCCGCTG
GCCGGTGGGCAGCCGCATCCCCACCGAGCCGGAACTGGCCGACGAGTTGGGCATCAGCCGCAACACCGTGCGCGAAGCGG
TGCGGGTGCTGCTGTACGCCGGCCTGCTGGAGGTGCGCCAGGGCGACGGCACCTATGTCCGCGCCATCGTCAATCCGGGC
GAGGCGATGCGCGCGCTCAGCCGCGCCAGCCTGCGCGAGCACCTGGAAGTGCGCTGCCTGCTGGAGGAGAGCGCGGCCAG
GCTGGCCGCCGAGCGCGCCGGCGCCGGCGACATCGCCCGCATCGCCGCCACGCTGGACGGGCTGCAACGCCGGGACGGCG
AAACGCCGGAAAGCTACGCCGAGCGCGATCTCGCCTTCCACGTCGCCATCGCCGACGCCAGCGGCAACCAGGCGCTGGCC
GGCCTGTACCACTTTTTCTCGCGCGCGGTGCGCCAGAGCGTGCAGGACTCCATCCGCGACGAGGCGCTGCCCGACCCGGA
CTTCGCCGCCCACGCCGCCATCTTCGACGCGATCCGGCAAGGCCGGCCGGACGAAGCCGGCCGCGCCGCCGCCGCCATCA
CCCGCCCGCTGCTGGCCACGCTGGACCGGCTGCTGGACACAAAACAATAA

Upstream 100 bases:

>100_bases
GGCTTCTCCGCCATCGCCTGAGCGATTTTCCCCGCCCTTTGCTCCATGCCGCGTTTGGCGGTAAAATTCATCGGATGATT
GGATGTTTAATCGGACTCCC

Downstream 100 bases:

>100_bases
GGAAGCACGATGCAAGAAAACATGGGGCGATCCAAAGCTATCGCCGACGAACTGTTGATTGACGACGAAGCCGCGCCGCG
AACCGGCAGCCGCCATCGCG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MNISSSKRSLVDIAVDNLGKQLEQGRWPVGSRIPTEPELADELGISRNTVREAVRVLLYAGLLEVRQGDGTYVRAIVNPG
EAMRALSRASLREHLEVRCLLEESAARLAAERAGAGDIARIAATLDGLQRRDGETPESYAERDLAFHVAIADASGNQALA
GLYHFFSRAVRQSVQDSIRDEALPDPDFAAHAAIFDAIRQGRPDEAGRAAAAITRPLLATLDRLLDTKQ

Sequences:

>Translated_229_residues
MNISSSKRSLVDIAVDNLGKQLEQGRWPVGSRIPTEPELADELGISRNTVREAVRVLLYAGLLEVRQGDGTYVRAIVNPG
EAMRALSRASLREHLEVRCLLEESAARLAAERAGAGDIARIAATLDGLQRRDGETPESYAERDLAFHVAIADASGNQALA
GLYHFFSRAVRQSVQDSIRDEALPDPDFAAHAAIFDAIRQGRPDEAGRAAAAITRPLLATLDRLLDTKQ
>Mature_229_residues
MNISSSKRSLVDIAVDNLGKQLEQGRWPVGSRIPTEPELADELGISRNTVREAVRVLLYAGLLEVRQGDGTYVRAIVNPG
EAMRALSRASLREHLEVRCLLEESAARLAAERAGAGDIARIAATLDGLQRRDGETPESYAERDLAFHVAIADASGNQALA
GLYHFFSRAVRQSVQDSIRDEALPDPDFAAHAAIFDAIRQGRPDEAGRAAAAITRPLLATLDRLLDTKQ

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=230, Percent_Identity=31.7391304347826, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI48994955, Length=214, Percent_Identity=32.7102803738318, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082208, Length=168, Percent_Identity=34.5238095238095, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1789353, Length=222, Percent_Identity=28.3783783783784, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790780, Length=154, Percent_Identity=36.3636363636364, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI48994961, Length=227, Percent_Identity=28.1938325991189, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786303, Length=212, Percent_Identity=30.188679245283, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789621, Length=226, Percent_Identity=26.5486725663717, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 24861; Mature: 24861

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISSSKRSLVDIAVDNLGKQLEQGRWPVGSRIPTEPELADELGISRNTVREAVRVLLYA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHH
GLLEVRQGDGTYVRAIVNPGEAMRALSRASLREHLEVRCLLEESAARLAAERAGAGDIAR
HHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IAATLDGLQRRDGETPESYAERDLAFHVAIADASGNQALAGLYHFFSRAVRQSVQDSIRD
HHHHHHHHHHCCCCCHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EALPDPDFAAHAAIFDAIRQGRPDEAGRAAAAITRPLLATLDRLLDTKQ
HCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNISSSKRSLVDIAVDNLGKQLEQGRWPVGSRIPTEPELADELGISRNTVREAVRVLLYA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHH
GLLEVRQGDGTYVRAIVNPGEAMRALSRASLREHLEVRCLLEESAARLAAERAGAGDIAR
HHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IAATLDGLQRRDGETPESYAERDLAFHVAIADASGNQALAGLYHFFSRAVRQSVQDSIRD
HHHHHHHHHHCCCCCHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EALPDPDFAAHAAIFDAIRQGRPDEAGRAAAAITRPLLATLDRLLDTKQ
HCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]