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The map label for this gene is hlyB [H]

Identifier: 34499104

GI number: 34499104

Start: 3946637

End: 3948652

Strand: Direct

Name: hlyB [H]

Synonym: CV_3649

Alternate gene names: 34499104

Gene position: 3946637-3948652 (Clockwise)

Preceding gene: 34499103

Following gene: 34499106

Centisome position: 83.07

GC content: 67.46

Gene sequence:

>2016_bases
ATGTCCACGCCCATCGTCAGGCTGATGCAGCGCCTGAGCTATCCGCAGCGCTTCGCCGTGATCGGCGTGCTGTTCGCCGC
GGCGCTGCTGTACCTGGTCTACGGTCTGTACCGCAGCAACCAGGACAATATCGAATCCACCGCCAAGGAAAAAGTGGGCG
TCGCCTACATGCGGCCGCTGACCGCGATGCTGGCCCAGGCGCAGCAAGGCCAGGAAGTGGCGGTGCGCGCCGCGCTGGGC
AACGCCCAGGCCCGGAACGAGCTGCCCTCGGCCATGCAGCAGCTGCAAGGCAAGTGGCAGGCGCTGCAGGACGCCAACGG
CCGGCTAGGCGCCGAGCTGGCCAGCGACGCCGCCTGGAAGGACGCCTCTGCCGCCTGGGACAAGCTGAAGGCCACGCAAT
CCGCCCAGCCTACGCAATGGATCGCTGCCTACGGCAATCTCAGCGACAAGCTGAATAATCTGATCGGCGTCATCAGCGAC
AATTCCAACCTGACGCTGGATCCGGACATCGACACTTATTACCTGATGGACGCCGCCACCGCCAAGCTGACCACGCTGAT
CAGCCATCTGGGCGAGGCCAACGCCATCGCCTCGCTGGCGGAAGCCGGCCACCCGCTCGATCCCGCCCAGCGCGACCGCC
TGGTGGAGCTGAGGCCGCTGATCGCCGAAGTCAATGACGGCCTGGGCAGCGACATCGCCAAGGCCGTCGCCTACAACGCC
GCGCTGAAAGCGGACATGGCGTCCCAGGCGGACAAGCTCGCGGCGGCGCTGAAAGGCCAGCTGCCGGCGATAGACGACGC
GGTCGGCGGCAAGACGGGCGCAAGCGGGCTGAAGGTGGCCGGGCACAGCGCCGACGCCGCCCAGACCGTCGCCGCCTACA
TCGACGCCGGCCTGGGCCGCCTGGATCAGCTGCTGCAGGCGCGGATAGACCGCACCGCCAGCCAGCGCAACAGCTACATC
GCCATCGGGGTCGCATCGATGCTGCTGGCCATCTTCCTGTTCCACCAGCTCTACCTGTCCATCACGCTGCAGCTGGGCGG
CGAGCCGCGCTACGTGCAACAGGTGGTGGAACAGCTGGCGGCCGGCCGGCTGGATACCCGCATCCACCTGCGCGAGCGGG
ACGAGCTCAGCCTGCTGGCGGCGATCCGCCAGATGCGCAACCAGTTGCGCGAAACCGTGAGCCAGTTGCTGGAGACCTCG
GGCGAGGTCACCCGGGCCGCCGACGCGATGGCCCACAGCGCGCAAAGCATCTCCGTCGGCAGCGCCCAGCAGAGCGAGGC
GGCCGCCAGCATGGCGGCGGCGATAGAGCAGCTGAGCACCAGCCTGTCGGTGTGCGCGGAACAGTCCGAACAGGCCGACC
GCTTGTCGACAGACGCGGCCAGCCGCTCGTCGGACGGCAACCGGGTGATCGCCGCCACCGCCAGCACCATGGACGGCATC
GTGCGCGACGTGTCCTCGGTATCCGACACCATCACCGACCTGGGCCGGCAGTCCGAATCCATCGTCGGCATCGTCGACGT
GATCCGCGACGTGGCCGATCAGACCAATCTGCTGGCCTTGAACGCGGCGATCGAGGCCGCGCGCGCCGGCGAAATGGGCC
GCGGCTTCGCGGTGGTGGCCGACGAGGTGAGGAAGCTGGCGGAGCGCACCGCGCTGTCGACCACGGAAATCAGCAATATC
GTCAACCAGATCCAGAACACCGCGCAGAAAGGCAACGACAGCATGCAACAGGGCATGAAATCCATCATGGACGGCCAGCA
GCGCGCCCGCGAAGCGGGTTCCAGCATGGACAACATCCGCCACTGCGTCGACGACGTGCTGGACAGCATCCACCAGATCA
CCTCCTCGCTGCGCGAGCAGAGCAGCGCCAGCCAGGCGCTGGCGCTGAACGTGGAGCAGGTGTCGAAGATGTCGGAGCAA
AACAGCATGGCGGTCCGGGACAGCGCGCAAACCGCCGGCGAGCTGCAGGCCATCTCGCAAAGACTGACGGGCCTGGCCGG
ACGCTTCACCGTCTGA

Upstream 100 bases:

>100_bases
TATTTTTCCCTGCGTGGTAAGCAAAATCACTTATACAAAGGGTATGCAAGCGTGCCGGGCAGAACCAGGCGCGGCAGCCC
GCTTTTGCAAGGAGCCGCCC

Downstream 100 bases:

>100_bases
CCGCCGGGCTCGCCCGCGCCGTCCAAACAAAAAGCCCGCCGGAAACGGCGGGCTTCGTCATCGCGGATTGGGAGACAGGC
TTACCAGACGCCCTTCTCCA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MSTPIVRLMQRLSYPQRFAVIGVLFAAALLYLVYGLYRSNQDNIESTAKEKVGVAYMRPLTAMLAQAQQGQEVAVRAALG
NAQARNELPSAMQQLQGKWQALQDANGRLGAELASDAAWKDASAAWDKLKATQSAQPTQWIAAYGNLSDKLNNLIGVISD
NSNLTLDPDIDTYYLMDAATAKLTTLISHLGEANAIASLAEAGHPLDPAQRDRLVELRPLIAEVNDGLGSDIAKAVAYNA
ALKADMASQADKLAAALKGQLPAIDDAVGGKTGASGLKVAGHSADAAQTVAAYIDAGLGRLDQLLQARIDRTASQRNSYI
AIGVASMLLAIFLFHQLYLSITLQLGGEPRYVQQVVEQLAAGRLDTRIHLRERDELSLLAAIRQMRNQLRETVSQLLETS
GEVTRAADAMAHSAQSISVGSAQQSEAAASMAAAIEQLSTSLSVCAEQSEQADRLSTDAASRSSDGNRVIAATASTMDGI
VRDVSSVSDTITDLGRQSESIVGIVDVIRDVADQTNLLALNAAIEAARAGEMGRGFAVVADEVRKLAERTALSTTEISNI
VNQIQNTAQKGNDSMQQGMKSIMDGQQRAREAGSSMDNIRHCVDDVLDSIHQITSSLREQSSASQALALNVEQVSKMSEQ
NSMAVRDSAQTAGELQAISQRLTGLAGRFTV

Sequences:

>Translated_671_residues
MSTPIVRLMQRLSYPQRFAVIGVLFAAALLYLVYGLYRSNQDNIESTAKEKVGVAYMRPLTAMLAQAQQGQEVAVRAALG
NAQARNELPSAMQQLQGKWQALQDANGRLGAELASDAAWKDASAAWDKLKATQSAQPTQWIAAYGNLSDKLNNLIGVISD
NSNLTLDPDIDTYYLMDAATAKLTTLISHLGEANAIASLAEAGHPLDPAQRDRLVELRPLIAEVNDGLGSDIAKAVAYNA
ALKADMASQADKLAAALKGQLPAIDDAVGGKTGASGLKVAGHSADAAQTVAAYIDAGLGRLDQLLQARIDRTASQRNSYI
AIGVASMLLAIFLFHQLYLSITLQLGGEPRYVQQVVEQLAAGRLDTRIHLRERDELSLLAAIRQMRNQLRETVSQLLETS
GEVTRAADAMAHSAQSISVGSAQQSEAAASMAAAIEQLSTSLSVCAEQSEQADRLSTDAASRSSDGNRVIAATASTMDGI
VRDVSSVSDTITDLGRQSESIVGIVDVIRDVADQTNLLALNAAIEAARAGEMGRGFAVVADEVRKLAERTALSTTEISNI
VNQIQNTAQKGNDSMQQGMKSIMDGQQRAREAGSSMDNIRHCVDDVLDSIHQITSSLREQSSASQALALNVEQVSKMSEQ
NSMAVRDSAQTAGELQAISQRLTGLAGRFTV
>Mature_670_residues
STPIVRLMQRLSYPQRFAVIGVLFAAALLYLVYGLYRSNQDNIESTAKEKVGVAYMRPLTAMLAQAQQGQEVAVRAALGN
AQARNELPSAMQQLQGKWQALQDANGRLGAELASDAAWKDASAAWDKLKATQSAQPTQWIAAYGNLSDKLNNLIGVISDN
SNLTLDPDIDTYYLMDAATAKLTTLISHLGEANAIASLAEAGHPLDPAQRDRLVELRPLIAEVNDGLGSDIAKAVAYNAA
LKADMASQADKLAAALKGQLPAIDDAVGGKTGASGLKVAGHSADAAQTVAAYIDAGLGRLDQLLQARIDRTASQRNSYIA
IGVASMLLAIFLFHQLYLSITLQLGGEPRYVQQVVEQLAAGRLDTRIHLRERDELSLLAAIRQMRNQLRETVSQLLETSG
EVTRAADAMAHSAQSISVGSAQQSEAAASMAAAIEQLSTSLSVCAEQSEQADRLSTDAASRSSDGNRVIAATASTMDGIV
RDVSSVSDTITDLGRQSESIVGIVDVIRDVADQTNLLALNAAIEAARAGEMGRGFAVVADEVRKLAERTALSTTEISNIV
NQIQNTAQKGNDSMQQGMKSIMDGQQRAREAGSSMDNIRHCVDDVLDSIHQITSSLREQSSASQALALNVEQVSKMSEQN
SMAVRDSAQTAGELQAISQRLTGLAGRFTV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=315, Percent_Identity=32.0634920634921, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1788194, Length=361, Percent_Identity=30.4709141274238, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI2367378, Length=330, Percent_Identity=31.5151515151515, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI1787690, Length=315, Percent_Identity=29.8412698412698, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1789453, Length=317, Percent_Identity=29.6529968454259, Blast_Score=113, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 71372; Mature: 71241

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPIVRLMQRLSYPQRFAVIGVLFAAALLYLVYGLYRSNQDNIESTAKEKVGVAYMRPL
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TAMLAQAQQGQEVAVRAALGNAQARNELPSAMQQLQGKWQALQDANGRLGAELASDAAWK
HHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC
DASAAWDKLKATQSAQPTQWIAAYGNLSDKLNNLIGVISDNSNLTLDPDIDTYYLMDAAT
HHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHEEEEECCCCEEECCCCCEEEEHHHHH
AKLTTLISHLGEANAIASLAEAGHPLDPAQRDRLVELRPLIAEVNDGLGSDIAKAVAYNA
HHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
ALKADMASQADKLAAALKGQLPAIDDAVGGKTGASGLKVAGHSADAAQTVAAYIDAGLGR
HHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHH
LDQLLQARIDRTASQRNSYIAIGVASMLLAIFLFHQLYLSITLQLGGEPRYVQQVVEQLA
HHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AGRLDTRIHLRERDELSLLAAIRQMRNQLRETVSQLLETSGEVTRAADAMAHSAQSISVG
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
SAQQSEAAASMAAAIEQLSTSLSVCAEQSEQADRLSTDAASRSSDGNRVIAATASTMDGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHH
VRDVSSVSDTITDLGRQSESIVGIVDVIRDVADQTNLLALNAAIEAARAGEMGRGFAVVA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCHHHHH
DEVRKLAERTALSTTEISNIVNQIQNTAQKGNDSMQQGMKSIMDGQQRAREAGSSMDNIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
HCVDDVLDSIHQITSSLREQSSASQALALNVEQVSKMSEQNSMAVRDSAQTAGELQAISQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RLTGLAGRFTV
HHHHCCCCCCC
>Mature Secondary Structure 
STPIVRLMQRLSYPQRFAVIGVLFAAALLYLVYGLYRSNQDNIESTAKEKVGVAYMRPL
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TAMLAQAQQGQEVAVRAALGNAQARNELPSAMQQLQGKWQALQDANGRLGAELASDAAWK
HHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC
DASAAWDKLKATQSAQPTQWIAAYGNLSDKLNNLIGVISDNSNLTLDPDIDTYYLMDAAT
HHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHEEEEECCCCEEECCCCCEEEEHHHHH
AKLTTLISHLGEANAIASLAEAGHPLDPAQRDRLVELRPLIAEVNDGLGSDIAKAVAYNA
HHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
ALKADMASQADKLAAALKGQLPAIDDAVGGKTGASGLKVAGHSADAAQTVAAYIDAGLGR
HHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHH
LDQLLQARIDRTASQRNSYIAIGVASMLLAIFLFHQLYLSITLQLGGEPRYVQQVVEQLA
HHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AGRLDTRIHLRERDELSLLAAIRQMRNQLRETVSQLLETSGEVTRAADAMAHSAQSISVG
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
SAQQSEAAASMAAAIEQLSTSLSVCAEQSEQADRLSTDAASRSSDGNRVIAATASTMDGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHH
VRDVSSVSDTITDLGRQSESIVGIVDVIRDVADQTNLLALNAAIEAARAGEMGRGFAVVA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCHHHHH
DEVRKLAERTALSTTEISNIVNQIQNTAQKGNDSMQQGMKSIMDGQQRAREAGSSMDNIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
HCVDDVLDSIHQITSSLREQSSASQALALNVEQVSKMSEQNSMAVRDSAQTAGELQAISQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RLTGLAGRFTV
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]