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The map label for this gene is anr [H]

Identifier: 34499102

GI number: 34499102

Start: 3944208

End: 3944954

Strand: Reverse

Name: anr [H]

Synonym: CV_3647

Alternate gene names: 34499102

Gene position: 3944954-3944208 (Counterclockwise)

Preceding gene: 34499105

Following gene: 34499099

Centisome position: 83.03

GC content: 63.32

Gene sequence:

>747_bases
ATGTCTGAACAAAACCACACCTCCCTGCATACGCTGAAAATCTCCTGCTCCAGCTGCAGTCTGCGCGAGCTGTGCCTGCC
CGTCGGCCTGAACCGCGAGGAAATGGGCCAGCTGGACGCGGTCATCCGCCAGAGCCGCCGCCTGAAGCGCGGCGAATACC
TGTTCCGTAGCGGCGAGTCCTTCAAGTCGCTGTACGCGATCCGCACCGGCTTCTTCAAAACCTGTGTCGCCAGCCAGGAC
GGCCGCGAGCAGGTGACAGGCTTCCTGATGTCGGGCGAGCTGATGGGCCTGGACGGCATTTCGTCCAGCAACCACAGCTG
CGACGCGGTGGCGCTGGAGGACAGCGAGGTATGCGAGCTGCCGTTCACCCGCATGGAGTCGCTGTGCCGCGACATCCCCA
GCCTGCAGCACCATTTCTACCGGCTGATGAGCCGCGAGATCGTGCGCGACCAGAACGTGATGCTGCTGCTGGGCAATATG
AAGGCGGAGGAGCGCATCGCCGCCTTCCTGCTGAACCTGTCGCAGCGCTTGTCCACCCGCGGCTTCGCCGCCAACGACTT
CATCCTGCGCATGAGCCGCGAGGAGATCGGCAGCTTCCTGGGCCTGAAACTGGAAACGGTCAGCCGCACGCTGTCCAAGT
TCCAGCAGCAAGGCTGGATCACCGTTGATCACAAGCACATCCAGCTGGTGCAGCTGGCCGAGCTGAAGAACCTGATCTCG
GGCTGCATGCACGCCGACGGCCACTGA

Upstream 100 bases:

>100_bases
TTCGGATGGTAAAACTTCTGGAGGACTGGTAAATTTGCGAAAAACTTGTGAATTCCGCCTTGATAAGGGTCAAGCTTCGC
CGGCTTGTAGCAAACACAGC

Downstream 100 bases:

>100_bases
GCCGGCGGAAGGTCTTTGCGACAAAGGCAGGCGCGCAGCCTGCCTTTTTTCATGCCTGCGCGATCTTGAGCCGCAGCGCG
GCCAGGCGCTCGGCGTCCGG

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSEQNHTSLHTLKISCSSCSLRELCLPVGLNREEMGQLDAVIRQSRRLKRGEYLFRSGESFKSLYAIRTGFFKTCVASQD
GREQVTGFLMSGELMGLDGISSSNHSCDAVALEDSEVCELPFTRMESLCRDIPSLQHHFYRLMSREIVRDQNVMLLLGNM
KAEERIAAFLLNLSQRLSTRGFAANDFILRMSREEIGSFLGLKLETVSRTLSKFQQQGWITVDHKHIQLVQLAELKNLIS
GCMHADGH

Sequences:

>Translated_248_residues
MSEQNHTSLHTLKISCSSCSLRELCLPVGLNREEMGQLDAVIRQSRRLKRGEYLFRSGESFKSLYAIRTGFFKTCVASQD
GREQVTGFLMSGELMGLDGISSSNHSCDAVALEDSEVCELPFTRMESLCRDIPSLQHHFYRLMSREIVRDQNVMLLLGNM
KAEERIAAFLLNLSQRLSTRGFAANDFILRMSREEIGSFLGLKLETVSRTLSKFQQQGWITVDHKHIQLVQLAELKNLIS
GCMHADGH
>Mature_247_residues
SEQNHTSLHTLKISCSSCSLRELCLPVGLNREEMGQLDAVIRQSRRLKRGEYLFRSGESFKSLYAIRTGFFKTCVASQDG
REQVTGFLMSGELMGLDGISSSNHSCDAVALEDSEVCELPFTRMESLCRDIPSLQHHFYRLMSREIVRDQNVMLLLGNMK
AEERIAAFLLNLSQRLSTRGFAANDFILRMSREEIGSFLGLKLETVSRTLSKFQQQGWITVDHKHIQLVQLAELKNLISG
CMHADGH

Specific function: Transcriptional activator of anaerobic gene expression [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=216, Percent_Identity=45.3703703703704, Blast_Score=211, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 28064; Mature: 27933

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQNHTSLHTLKISCSSCSLRELCLPVGLNREEMGQLDAVIRQSRRLKRGEYLFRSGES
CCCCCCCEEEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
FKSLYAIRTGFFKTCVASQDGREQVTGFLMSGELMGLDGISSSNHSCDAVALEDSEVCEL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCEEEECCCCHHCC
PFTRMESLCRDIPSLQHHFYRLMSREIVRDQNVMLLLGNMKAEERIAAFLLNLSQRLSTR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC
GFAANDFILRMSREEIGSFLGLKLETVSRTLSKFQQQGWITVDHKHIQLVQLAELKNLIS
CCCCCHHHEEECHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHH
GCMHADGH
HHHCCCCC
>Mature Secondary Structure 
SEQNHTSLHTLKISCSSCSLRELCLPVGLNREEMGQLDAVIRQSRRLKRGEYLFRSGES
CCCCCCEEEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
FKSLYAIRTGFFKTCVASQDGREQVTGFLMSGELMGLDGISSSNHSCDAVALEDSEVCEL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCCEEEECCCCHHCC
PFTRMESLCRDIPSLQHHFYRLMSREIVRDQNVMLLLGNMKAEERIAAFLLNLSQRLSTR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC
GFAANDFILRMSREEIGSFLGLKLETVSRTLSKFQQQGWITVDHKHIQLVQLAELKNLIS
CCCCCHHHEEECHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHH
GCMHADGH
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1787797; 1787798; 10984043 [H]