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The map label for this gene is dcuA [H]

Identifier: 34499090

GI number: 34499090

Start: 3935226

End: 3936536

Strand: Reverse

Name: dcuA [H]

Synonym: CV_3635

Alternate gene names: 34499090

Gene position: 3936536-3935226 (Counterclockwise)

Preceding gene: 34499091

Following gene: 34499086

Centisome position: 82.86

GC content: 68.04

Gene sequence:

>1311_bases
ATGGTATACCTGCAACTCGTAGTCGTGCTGGGGCTGATCTTCCTCGGCGTGCGCATGGGCGGCATCGGGCTGGGCGTCAC
CGGCGGCGCCGGCTTGTTCATCCTGACATTCGTCTTCGGCCTGAAACCCGGCCACGCGCCGATAGACGTGATCCTGATCA
TCATCTCGGTCATCACCGCGTCCGCCGCGCTGCAATCGGCGCGCGGGCTGGACTACATGGTCGGCGTGGCCGCCCGGCTG
CTGCGGCGCAATCCCCGCCACATCGTGCTGCTGGCGCCGCTGGTGGGCTGGCTGTCCACCTTCCTTGCCGGCACCGGCTT
CATCGCGCTGGCGCTGATGCCCATCGTGGTGGAAGTGGCGGAGAAGACCGGCATCCGGCCCGAGCGGCCGCTGGCGGGCC
TGACCGTGGCGTCGCAGAACGCCATCGTCGCTTGTCCGGTATCCGCCGCCACGGTGGCGCTGGCCACGGTGCTGGCGCCG
CACGGCGTCGCGCTGACCGACATCATCATGATCAGCATTCCGGCCACGCTGCTGGGCGCGCTGGCGGGCGGGGCGGTGAT
GCTGCGCTACGGCTGCGAACTGGCCGACGATCCCGTCTACCGCCAGCGGCTGGCCGACGGCGGCATCCGCCGGCCGCAGA
CCGACGCCGAGGAGGCCTTGCCGCGCACCGCCGCCTGGTCGGTTTACGGTTTCCTGCTGACGGTGGCGCTGATCGTGCTC
TTGGCGGCGATGCCGCAGCTGCGCCCGGCCTGGCCCGGCGCCAAGGGCATGGAGCCGGTGGCGATGGTGGACGTGATCCA
GATGTGCATGCTGGGTTATTCCGCGCTGGCCGTGCTGGTATGCAAGGCCGACCTGCAGGGCATGGTGTCGGGCAGCATGT
TCCGCTCCGGCGCGGTGGCGGCGGTGACGATACTGGGCGCGGCGTGGATGAGCGATACCTTTATCCAGGCCAATCTGCCG
CTGTTCAAACACAATATCGTCAGCATCATCGAGTCGGCGCCATGGCTGTTCGCCTTCGCGGTGTTCACGATGGCGGTGAT
CCTGTTCAGCCAGGGGGCGACCACCAAGGTGATGATGCCGCTGGGGGTGTCGCTGGGAATCGCGTCGCCGGTGCTGATCG
CCATCTATCCGGCGGTAGTGGGCGTCTACGTGCTGCCCAGCTATCCCAGCCTGATCGCGGCGGTGGAGATGGATTACACC
GGAACCACCCGCATCGGCCGCTGGGTGTTCAACCACAGCTTCATCCTGCCGGGGCTGGCGAGCACCGCGGTGTCGATCGC
GGCCGGCTTCGCCTTGCTGGCCTTGAGGTGA

Upstream 100 bases:

>100_bases
CGCGGGAGCTGTAAGAGCATAAGCGTATCCTGATCTTGGACAATCCGCAGGCGTGGCATTATTGCGACAATGGGGCCCTG
ATCCTGCGGAAAGTCGCATC

Downstream 100 bases:

>100_bases
CTTACTCTTCCGTTTTCAGCACGACGCGGGCGCGCAGGCCCGGGGCGCCCTGTTCGGCGATGGCCAGCAGGCGGTCGATG
TTGGGGTGGCTGCCGGGATG

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MVYLQLVVVLGLIFLGVRMGGIGLGVTGGAGLFILTFVFGLKPGHAPIDVILIIISVITASAALQSARGLDYMVGVAARL
LRRNPRHIVLLAPLVGWLSTFLAGTGFIALALMPIVVEVAEKTGIRPERPLAGLTVASQNAIVACPVSAATVALATVLAP
HGVALTDIIMISIPATLLGALAGGAVMLRYGCELADDPVYRQRLADGGIRRPQTDAEEALPRTAAWSVYGFLLTVALIVL
LAAMPQLRPAWPGAKGMEPVAMVDVIQMCMLGYSALAVLVCKADLQGMVSGSMFRSGAVAAVTILGAAWMSDTFIQANLP
LFKHNIVSIIESAPWLFAFAVFTMAVILFSQGATTKVMMPLGVSLGIASPVLIAIYPAVVGVYVLPSYPSLIAAVEMDYT
GTTRIGRWVFNHSFILPGLASTAVSIAAGFALLALR

Sequences:

>Translated_436_residues
MVYLQLVVVLGLIFLGVRMGGIGLGVTGGAGLFILTFVFGLKPGHAPIDVILIIISVITASAALQSARGLDYMVGVAARL
LRRNPRHIVLLAPLVGWLSTFLAGTGFIALALMPIVVEVAEKTGIRPERPLAGLTVASQNAIVACPVSAATVALATVLAP
HGVALTDIIMISIPATLLGALAGGAVMLRYGCELADDPVYRQRLADGGIRRPQTDAEEALPRTAAWSVYGFLLTVALIVL
LAAMPQLRPAWPGAKGMEPVAMVDVIQMCMLGYSALAVLVCKADLQGMVSGSMFRSGAVAAVTILGAAWMSDTFIQANLP
LFKHNIVSIIESAPWLFAFAVFTMAVILFSQGATTKVMMPLGVSLGIASPVLIAIYPAVVGVYVLPSYPSLIAAVEMDYT
GTTRIGRWVFNHSFILPGLASTAVSIAAGFALLALR
>Mature_436_residues
MVYLQLVVVLGLIFLGVRMGGIGLGVTGGAGLFILTFVFGLKPGHAPIDVILIIISVITASAALQSARGLDYMVGVAARL
LRRNPRHIVLLAPLVGWLSTFLAGTGFIALALMPIVVEVAEKTGIRPERPLAGLTVASQNAIVACPVSAATVALATVLAP
HGVALTDIIMISIPATLLGALAGGAVMLRYGCELADDPVYRQRLADGGIRRPQTDAEEALPRTAAWSVYGFLLTVALIVL
LAAMPQLRPAWPGAKGMEPVAMVDVIQMCMLGYSALAVLVCKADLQGMVSGSMFRSGAVAAVTILGAAWMSDTFIQANLP
LFKHNIVSIIESAPWLFAFAVFTMAVILFSQGATTKVMMPLGVSLGIASPVLIAIYPAVVGVYVLPSYPSLIAAVEMDYT
GTTRIGRWVFNHSFILPGLASTAVSIAAGFALLALR

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790580, Length=436, Percent_Identity=40.8256880733945, Blast_Score=307, Evalue=9e-85,
Organism=Escherichia coli, GI1790565, Length=409, Percent_Identity=36.919315403423, Blast_Score=253, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 45559; Mature: 45559

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYLQLVVVLGLIFLGVRMGGIGLGVTGGAGLFILTFVFGLKPGHAPIDVILIIISVITA
CHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
SAALQSARGLDYMVGVAARLLRRNPRHIVLLAPLVGWLSTFLAGTGFIALALMPIVVEVA
HHHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKTGIRPERPLAGLTVASQNAIVACPVSAATVALATVLAPHGVALTDIIMISIPATLLGA
HHCCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LAGGAVMLRYGCELADDPVYRQRLADGGIRRPQTDAEEALPRTAAWSVYGFLLTVALIVL
HHCCHHEEHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
LAAMPQLRPAWPGAKGMEPVAMVDVIQMCMLGYSALAVLVCKADLQGMVSGSMFRSGAVA
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AVTILGAAWMSDTFIQANLPLFKHNIVSIIESAPWLFAFAVFTMAVILFSQGATTKVMMP
HHHHHHHHHHCCCCEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEC
LGVSLGIASPVLIAIYPAVVGVYVLPSYPSLIAAVEMDYTGTTRIGRWVFNHSFILPGLA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEECCCCCHHHHHHHHCCCEECCCHH
STAVSIAAGFALLALR
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVYLQLVVVLGLIFLGVRMGGIGLGVTGGAGLFILTFVFGLKPGHAPIDVILIIISVITA
CHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
SAALQSARGLDYMVGVAARLLRRNPRHIVLLAPLVGWLSTFLAGTGFIALALMPIVVEVA
HHHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKTGIRPERPLAGLTVASQNAIVACPVSAATVALATVLAPHGVALTDIIMISIPATLLGA
HHCCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LAGGAVMLRYGCELADDPVYRQRLADGGIRRPQTDAEEALPRTAAWSVYGFLLTVALIVL
HHCCHHEEHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
LAAMPQLRPAWPGAKGMEPVAMVDVIQMCMLGYSALAVLVCKADLQGMVSGSMFRSGAVA
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AVTILGAAWMSDTFIQANLPLFKHNIVSIIESAPWLFAFAVFTMAVILFSQGATTKVMMP
HHHHHHHHHHCCCCEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEC
LGVSLGIASPVLIAIYPAVVGVYVLPSYPSLIAAVEMDYTGTTRIGRWVFNHSFILPGLA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEECCCCCHHHHHHHHCCCEECCCHH
STAVSIAAGFALLALR
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]