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The map label for this gene is serB [H]

Identifier: 34498971

GI number: 34498971

Start: 3812910

End: 3813551

Strand: Direct

Name: serB [H]

Synonym: CV_3516

Alternate gene names: 34498971

Gene position: 3812910-3813551 (Clockwise)

Preceding gene: 34498970

Following gene: 34498972

Centisome position: 80.25

GC content: 64.64

Gene sequence:

>642_bases
CTGGCATTCGCCGATTTCGGCCTGCTGGTTTCCGACATGGACTCCACGCTGATCAATATCGAGTGCATAGACGAGATCGC
CGACATCAAGGGCATCAAGCCCCAGGTGGCCGAGATCACCGAACGAGCGATGCGGGGCGAGCTGGACTTCGCCGCCGCCC
TGCGCGAACGGGTGGCGCTGCTGAAAGGCCTGGATGAATCGGCGCTGCGTCAGGTTTACGAAGAGCGCTTGAGGCTGAAT
CCCGGCGCCGAGCGGCTGCTGGACGCCTGCAAGCGTTTCGGCATCAAGACCCTGCTGGTTTCCGGCGGCTTCACCTACTT
CACAGAGCGGCTGAAGGCCGACTACGGCCTGGATTACGCCTACGCCAACCAGTTGGAAATCATCGACGGCAAGCTGACCG
GCCGCCTGCAGGGCGACATCGTGGACGCGGAGGCCAAGAAGCGGCTGCTGATCGCCACCCGCGACGCGCTGGAGCTGAAT
CCCGGCCAGGTGATCGCCGTCGGCGACGGCGCCAACGACCTGCCCATGCTGCGCGAAGCCGGCATCGGCGTCGCCTACCA
TGCCAAACCCCGCGTCAGCGCCGAAGCCGACATCGCGATCGAACACGGCGGCCTCGATACCATCCTGCGCCTATTCCACT
GA

Upstream 100 bases:

>100_bases
CGATGTCGTGCGGATGCGCGGCGCCAACCCGGCCCATGGCGCATCGGTCCTGGAGCGCTGCCGCGCGCACGGCTACGATG
CCGCCTACGTCGACAGCAGC

Downstream 100 bases:

>100_bases
GCGACGACCATGGCCGACAAGCAAACGCCCGGACTGCTGGAGCTCGACACCGTCAGCTTCGACGCCGAACTGCCTTTTCT
CGCTCAGGCGCTGGAAGGCG

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MAFADFGLLVSDMDSTLINIECIDEIADIKGIKPQVAEITERAMRGELDFAAALRERVALLKGLDESALRQVYEERLRLN
PGAERLLDACKRFGIKTLLVSGGFTYFTERLKADYGLDYAYANQLEIIDGKLTGRLQGDIVDAEAKKRLLIATRDALELN
PGQVIAVGDGANDLPMLREAGIGVAYHAKPRVSAEADIAIEHGGLDTILRLFH

Sequences:

>Translated_213_residues
MAFADFGLLVSDMDSTLINIECIDEIADIKGIKPQVAEITERAMRGELDFAAALRERVALLKGLDESALRQVYEERLRLN
PGAERLLDACKRFGIKTLLVSGGFTYFTERLKADYGLDYAYANQLEIIDGKLTGRLQGDIVDAEAKKRLLIATRDALELN
PGQVIAVGDGANDLPMLREAGIGVAYHAKPRVSAEADIAIEHGGLDTILRLFH
>Mature_212_residues
AFADFGLLVSDMDSTLINIECIDEIADIKGIKPQVAEITERAMRGELDFAAALRERVALLKGLDESALRQVYEERLRLNP
GAERLLDACKRFGIKTLLVSGGFTYFTERLKADYGLDYAYANQLEIIDGKLTGRLQGDIVDAEAKKRLLIATRDALELNP
GQVIAVGDGANDLPMLREAGIGVAYHAKPRVSAEADIAIEHGGLDTILRLFH

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=167, Percent_Identity=31.7365269461078, Blast_Score=81, Evalue=6e-16,
Organism=Escherichia coli, GI1790849, Length=199, Percent_Identity=53.7688442211055, Blast_Score=205, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6321647, Length=206, Percent_Identity=41.2621359223301, Blast_Score=145, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 23358; Mature: 23227

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFADFGLLVSDMDSTLINIECIDEIADIKGIKPQVAEITERAMRGELDFAAALRERVAL
CCCCHHHHHHHCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
LKGLDESALRQVYEERLRLNPGAERLLDACKRFGIKTLLVSGGFTYFTERLKADYGLDYA
HHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHCCCCCH
YANQLEIIDGKLTGRLQGDIVDAEAKKRLLIATRDALELNPGQVIAVGDGANDLPMLREA
HCCCEEEECCCCCCEECCCEECCHHHCEEEEEECCCEECCCCEEEEECCCCCCCHHHHHC
GIGVAYHAKPRVSAEADIAIEHGGLDTILRLFH
CCCEEEECCCCCCCCCEEEEECCCHHHHHHHHC
>Mature Secondary Structure 
AFADFGLLVSDMDSTLINIECIDEIADIKGIKPQVAEITERAMRGELDFAAALRERVAL
CCCHHHHHHHCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
LKGLDESALRQVYEERLRLNPGAERLLDACKRFGIKTLLVSGGFTYFTERLKADYGLDYA
HHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHCCCCCH
YANQLEIIDGKLTGRLQGDIVDAEAKKRLLIATRDALELNPGQVIAVGDGANDLPMLREA
HCCCEEEECCCCCCEECCCEECCHHHCEEEEEECCCEECCCCEEEEECCCCCCCHHHHHC
GIGVAYHAKPRVSAEADIAIEHGGLDTILRLFH
CCCEEEECCCCCCCCCEEEEECCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]