Click here to switch to the map view.

The map label for this gene is atoS [H]

Identifier: 34498900

GI number: 34498900

Start: 3741874

End: 3743019

Strand: Reverse

Name: atoS [H]

Synonym: CV_3445

Alternate gene names: 34498900

Gene position: 3743019-3741874 (Counterclockwise)

Preceding gene: 34498910

Following gene: 34498899

Centisome position: 78.78

GC content: 62.3

Gene sequence:

>1146_bases
CTGAAGGATCAGCAGCAGCTCGAGGCCGCGTTCGAGCAATTCAATGCGGTTTCCGGGCAACTCATTGATGCATATAGACA
ACTTGAGGTTCAGGTCAATGTTTTGAACGCTCAGTTGGACGAGGCGAACAGCCAGTTGCGAAAACAGCGCGACGAGAATG
CCGAGCTCGCGGAACGGCTGGCGTCGTTGCTCAAGATGCTGCCGGCCGGCGTGGTGGAGCTGTCTCCCGATGGGCGGGTC
ATCGCCGAGAATCTGGCGGCGGAATCGCTGATAAGCGGTTGTTATATAGGAGAATATTGGGAGGCTGTGCTGGAGCGGCT
GCTGACGCAGGAGGCGGATGGCAGCTTCGCGTTGGAGGCCGGCGGCGAGTCCAGGCGCCTGACGCTTCAATACCAGGATT
TGCCTGCGTCCGGGGGGCGGATTGTGCTTATTCACGACGTGACGCGGCTGCATCAGCTCAATAGCGAGCTCGCGCAGCAG
CAGAAACTGGCGTCGATGGGCAGCATGGCCGCCGCGCTGGCGCATCAGCTGCGCACGCCCTTGGCCAGCGCGATGTTGTA
TACGGCCAACTTGAAGCAGGATATTCCCCGTCCGGAAGACCGGGCGCGTTTTGTCGACAAGAGCCTGGCGAGGATGCGCG
CGCTGGAAGGCCTGATCCAGAACATGCTCGGTTTCGTGCGCGGCCAGGTGTCGTCGCTGGAGAAGGCGCCGCTGGAGCCG
CTGCTGGAAGACGTATGCGCCGTACTGGCCCCGCAATGCCATGACAAAGGTGTGTTTTTTGATTGCAATCTGCCCGCCGA
TTCTGCCATAACGGTCTTGATAGACCGCAAGGCGCTGCAGGGCGCGCTGATCAATCTGCTCGAGAATGCGCTGCAGTTCG
CGTCGCCGGGCGGGCGGGTCGGCCTGGCGGTGGCGAGCGACGGCGCCGATGTCGTATTCTGCGTCGAGGACGACGGGCCG
GGGATAGACGAAGCGGTGAGGGAGCGGATTTTCGAACCATTCTTCACGCAAAGGCCGGGCGGAACCGGCCTGGGGCTGGC
GATCGTGAAGAAGGTGGCCGAAGAGCTGGGGGGGAGTGTACGGTGTTACAACAAGGTGGCGGGCGGCGCCTGCTTCGAAT
TGAGGCTGCCGACGTGTCCGGCGTGA

Upstream 100 bases:

>100_bases
AGGCCTGCAGCGTGTTGGCGCGCCATGAGCTGGTCATTATCATACCGTTTAAGTGGTTTTTACAAATGACAGTGAAGCGA
TGCCGACTATGGTTTCAAGC

Downstream 100 bases:

>100_bases
GGCCGGATCCAGCTGCGTCGTTCGTTCAATGTGTTCGCGAACCTATGGAAAGCCGAGGACCAGTGATGAGACCGATAGTC
AGAGTAGAGGGGAATGTCGG

Product: two-component sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKDQQQLEAAFEQFNAVSGQLIDAYRQLEVQVNVLNAQLDEANSQLRKQRDENAELAERLASLLKMLPAGVVELSPDGRV
IAENLAAESLISGCYIGEYWEAVLERLLTQEADGSFALEAGGESRRLTLQYQDLPASGGRIVLIHDVTRLHQLNSELAQQ
QKLASMGSMAAALAHQLRTPLASAMLYTANLKQDIPRPEDRARFVDKSLARMRALEGLIQNMLGFVRGQVSSLEKAPLEP
LLEDVCAVLAPQCHDKGVFFDCNLPADSAITVLIDRKALQGALINLLENALQFASPGGRVGLAVASDGADVVFCVEDDGP
GIDEAVRERIFEPFFTQRPGGTGLGLAIVKKVAEELGGSVRCYNKVAGGACFELRLPTCPA

Sequences:

>Translated_381_residues
MKDQQQLEAAFEQFNAVSGQLIDAYRQLEVQVNVLNAQLDEANSQLRKQRDENAELAERLASLLKMLPAGVVELSPDGRV
IAENLAAESLISGCYIGEYWEAVLERLLTQEADGSFALEAGGESRRLTLQYQDLPASGGRIVLIHDVTRLHQLNSELAQQ
QKLASMGSMAAALAHQLRTPLASAMLYTANLKQDIPRPEDRARFVDKSLARMRALEGLIQNMLGFVRGQVSSLEKAPLEP
LLEDVCAVLAPQCHDKGVFFDCNLPADSAITVLIDRKALQGALINLLENALQFASPGGRVGLAVASDGADVVFCVEDDGP
GIDEAVRERIFEPFFTQRPGGTGLGLAIVKKVAEELGGSVRCYNKVAGGACFELRLPTCPA
>Mature_381_residues
MKDQQQLEAAFEQFNAVSGQLIDAYRQLEVQVNVLNAQLDEANSQLRKQRDENAELAERLASLLKMLPAGVVELSPDGRV
IAENLAAESLISGCYIGEYWEAVLERLLTQEADGSFALEAGGESRRLTLQYQDLPASGGRIVLIHDVTRLHQLNSELAQQ
QKLASMGSMAAALAHQLRTPLASAMLYTANLKQDIPRPEDRARFVDKSLARMRALEGLIQNMLGFVRGQVSSLEKAPLEP
LLEDVCAVLAPQCHDKGVFFDCNLPADSAITVLIDRKALQGALINLLENALQFASPGGRVGLAVASDGADVVFCVEDDGP
GIDEAVRERIFEPFFTQRPGGTGLGLAIVKKVAEELGGSVRCYNKVAGGACFELRLPTCPA

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=30.2040816326531, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1790436, Length=227, Percent_Identity=26.8722466960352, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081816, Length=215, Percent_Identity=31.1627906976744, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1789149, Length=222, Percent_Identity=29.2792792792793, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=30.3030303030303, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787894, Length=225, Percent_Identity=32.8888888888889, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87082128, Length=260, Percent_Identity=29.6153846153846, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=29.7071129707113, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1788393, Length=281, Percent_Identity=27.4021352313167, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790861, Length=212, Percent_Identity=32.0754716981132, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693157, Length=234, Percent_Identity=29.4871794871795, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=283, Percent_Identity=23.6749116607774, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786600, Length=358, Percent_Identity=24.5810055865922, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790551, Length=208, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI48994928, Length=224, Percent_Identity=26.3392857142857, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789808, Length=215, Percent_Identity=28.3720930232558, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787374, Length=244, Percent_Identity=25.8196721311475, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790300, Length=283, Percent_Identity=23.6749116607774, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41240; Mature: 41240

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDQQQLEAAFEQFNAVSGQLIDAYRQLEVQVNVLNAQLDEANSQLRKQRDENAELAERL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHCCCCHHHHHHH
ASLLKMLPAGVVELSPDGRVIAENLAAESLISGCYIGEYWEAVLERLLTQEADGSFALEA
HHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
GGESRRLTLQYQDLPASGGRIVLIHDVTRLHQLNSELAQQQKLASMGSMAAALAHQLRTP
CCCCCEEEEEEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LASAMLYTANLKQDIPRPEDRARFVDKSLARMRALEGLIQNMLGFVRGQVSSLEKAPLEP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LLEDVCAVLAPQCHDKGVFFDCNLPADSAITVLIDRKALQGALINLLENALQFASPGGRV
HHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCE
GLAVASDGADVVFCVEDDGPGIDEAVRERIFEPFFTQRPGGTGLGLAIVKKVAEELGGSV
EEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCE
RCYNKVAGGACFELRLPTCPA
EEHHHHCCCEEEEEECCCCCC
>Mature Secondary Structure
MKDQQQLEAAFEQFNAVSGQLIDAYRQLEVQVNVLNAQLDEANSQLRKQRDENAELAERL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHCCCCHHHHHHH
ASLLKMLPAGVVELSPDGRVIAENLAAESLISGCYIGEYWEAVLERLLTQEADGSFALEA
HHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
GGESRRLTLQYQDLPASGGRIVLIHDVTRLHQLNSELAQQQKLASMGSMAAALAHQLRTP
CCCCCEEEEEEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LASAMLYTANLKQDIPRPEDRARFVDKSLARMRALEGLIQNMLGFVRGQVSSLEKAPLEP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LLEDVCAVLAPQCHDKGVFFDCNLPADSAITVLIDRKALQGALINLLENALQFASPGGRV
HHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCE
GLAVASDGADVVFCVEDDGPGIDEAVRERIFEPFFTQRPGGTGLGLAIVKKVAEELGGSV
EEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCE
RCYNKVAGGACFELRLPTCPA
EEHHHHCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]