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The map label for this gene is oxyR [H]

Identifier: 34498833

GI number: 34498833

Start: 3672499

End: 3673437

Strand: Direct

Name: oxyR [H]

Synonym: CV_3378

Alternate gene names: 34498833

Gene position: 3672499-3673437 (Clockwise)

Preceding gene: 34498832

Following gene: 34498834

Centisome position: 77.3

GC content: 66.35

Gene sequence:

>939_bases
ATGACGCTGACCGAACTGCGCTACATCGTGGCGGTGGCGCGCGAGCGCCACTTCGGCCGCGCGGCCCAGAGCTGCTTCGT
CAGCCAGCCGACGCTGTCGATCGCCATCAAGAAGCTGGAAGACGAGCTGGGCATCACCCTGTTTGAACGCGGCGGCCAGG
AAGTGGCCGTCACCGAGATAGGCGAGCGCATCATCGAGCAGTCCCAGCGCGTGCTGGAGGAGGCCGAAGCGGTCAAGCGC
CTGGCCGGAGAGCACCAGAACGAGCTGGCCGGGCCGCTGAAGCTGGGCGTGATCTTCACGATCAGCCCCTACCTGCTGCC
CAAGCTGATTCCGGCGCTGCGCATCCTGGCGCCGGACATGCCGCTGATCCTGGAGGAGAACTACACCTCCCGGCTGGCAG
AAATGCTCAAGCGCGGCGAGGTCGACGCCATCATCGTCGCCGATCCTTTCGAAGAAACCGGCATCGAGGCCTGGCCGCTG
TACGACGAGCCCTTCGTCGTCGCCACGCCCAAGGGCCATCCCTGGGAAAAGCAGCAGGCGATCCAGCCCTGCCAGCTGGC
CGAGGAAAGCGTGCTGCTGCTGACTCAGGGCAACTGCTTCCGCGACCAGGTGCTGCAGACCTGCAGCGAGCTGTCCGCCC
GGCAGAACCACGGCAACAATCTGGCCAGCGCGCTGCAGGGCAGCTCGCTGAACACGATACGCCACATGGTGGCCAGCGGC
ATGGGCGTCACCGTGATGCCGGCCACCTCGGTCGGCTCCGGAGATGAATCGCTGCTGTCCATCGTGCCCTTCGACTCGCC
GGCGCCGCAGCGCCGCGTGCTGCTGGTGACGCGCAAGCAGTTCTTCCGCAAGAAGGCGATCGAGACGCTGCGCCAAGCGG
TGTTCCGCTCAGGCCTGCCCGATGTCGTCATGCTGGAAGGCGAGCCGAAGCTGGCATGA

Upstream 100 bases:

>100_bases
GTCCGTCAACCTGGAAGACATCAAGGTTCAGGTCGAGCGCCAGGACGACTACGAGGTCCTGGAAGTCAACATCGTGCTGC
CGGAGCACCAACGCTAAGCC

Downstream 100 bases:

>100_bases
CGCCGCCATTGCCCGACAAACCCGCCCGGCGTAGCCGAGGCGGGTTTTTCATATCCCAAAGGAGCGTCGCCATGCCGAAT
CCGAATACCGTCGAACTGAA

Product: hydrogen peroxide-inducible genes activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTLTELRYIVAVARERHFGRAAQSCFVSQPTLSIAIKKLEDELGITLFERGGQEVAVTEIGERIIEQSQRVLEEAEAVKR
LAGEHQNELAGPLKLGVIFTISPYLLPKLIPALRILAPDMPLILEENYTSRLAEMLKRGEVDAIIVADPFEETGIEAWPL
YDEPFVVATPKGHPWEKQQAIQPCQLAEESVLLLTQGNCFRDQVLQTCSELSARQNHGNNLASALQGSSLNTIRHMVASG
MGVTVMPATSVGSGDESLLSIVPFDSPAPQRRVLLVTRKQFFRKKAIETLRQAVFRSGLPDVVMLEGEPKLA

Sequences:

>Translated_312_residues
MTLTELRYIVAVARERHFGRAAQSCFVSQPTLSIAIKKLEDELGITLFERGGQEVAVTEIGERIIEQSQRVLEEAEAVKR
LAGEHQNELAGPLKLGVIFTISPYLLPKLIPALRILAPDMPLILEENYTSRLAEMLKRGEVDAIIVADPFEETGIEAWPL
YDEPFVVATPKGHPWEKQQAIQPCQLAEESVLLLTQGNCFRDQVLQTCSELSARQNHGNNLASALQGSSLNTIRHMVASG
MGVTVMPATSVGSGDESLLSIVPFDSPAPQRRVLLVTRKQFFRKKAIETLRQAVFRSGLPDVVMLEGEPKLA
>Mature_311_residues
TLTELRYIVAVARERHFGRAAQSCFVSQPTLSIAIKKLEDELGITLFERGGQEVAVTEIGERIIEQSQRVLEEAEAVKRL
AGEHQNELAGPLKLGVIFTISPYLLPKLIPALRILAPDMPLILEENYTSRLAEMLKRGEVDAIIVADPFEETGIEAWPLY
DEPFVVATPKGHPWEKQQAIQPCQLAEESVLLLTQGNCFRDQVLQTCSELSARQNHGNNLASALQGSSLNTIRHMVASGM
GVTVMPATSVGSGDESLLSIVPFDSPAPQRRVLLVTRKQFFRKKAIETLRQAVFRSGLPDVVMLEGEPKLA

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=295, Percent_Identity=37.6271186440678, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI1788887, Length=247, Percent_Identity=31.1740890688259, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI157672245, Length=286, Percent_Identity=26.9230769230769, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788748, Length=322, Percent_Identity=27.0186335403727, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787530, Length=297, Percent_Identity=26.2626262626263, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI145693105, Length=282, Percent_Identity=23.758865248227, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI2367136, Length=248, Percent_Identity=29.8387096774194, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788296, Length=246, Percent_Identity=28.4552845528455, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1787879, Length=253, Percent_Identity=30.0395256916996, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1787601, Length=175, Percent_Identity=28, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790208, Length=283, Percent_Identity=26.5017667844523, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081904, Length=174, Percent_Identity=29.3103448275862, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786401, Length=170, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787806, Length=176, Percent_Identity=26.1363636363636, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788481, Length=246, Percent_Identity=23.9837398373984, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34433; Mature: 34302

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTELRYIVAVARERHFGRAAQSCFVSQPTLSIAIKKLEDELGITLFERGGQEVAVTEI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEECCCCEEHHHHH
GERIIEQSQRVLEEAEAVKRLAGEHQNELAGPLKLGVIFTISPYLLPKLIPALRILAPDM
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHCCEEEEECHHHHHHHHHHHHHHCCCC
PLILEENYTSRLAEMLKRGEVDAIIVADPFEETGIEAWPLYDEPFVVATPKGHPWEKQQA
CEEECCCHHHHHHHHHHCCCCCEEEEECCHHHCCCEEECCCCCCEEEECCCCCCCCHHHC
IQPCQLAEESVLLLTQGNCFRDQVLQTCSELSARQNHGNNLASALQGSSLNTIRHMVASG
CCHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHCC
MGVTVMPATSVGSGDESLLSIVPFDSPAPQRRVLLVTRKQFFRKKAIETLRQAVFRSGLP
CCEEEEECCCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCC
DVVMLEGEPKLA
CEEEECCCCCCC
>Mature Secondary Structure 
TLTELRYIVAVARERHFGRAAQSCFVSQPTLSIAIKKLEDELGITLFERGGQEVAVTEI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEECCCCEEHHHHH
GERIIEQSQRVLEEAEAVKRLAGEHQNELAGPLKLGVIFTISPYLLPKLIPALRILAPDM
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHCCEEEEECHHHHHHHHHHHHHHCCCC
PLILEENYTSRLAEMLKRGEVDAIIVADPFEETGIEAWPLYDEPFVVATPKGHPWEKQQA
CEEECCCHHHHHHHHHHCCCCCEEEEECCHHHCCCEEECCCCCCEEEECCCCCCCCHHHC
IQPCQLAEESVLLLTQGNCFRDQVLQTCSELSARQNHGNNLASALQGSSLNTIRHMVASG
CCHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHCC
MGVTVMPATSVGSGDESLLSIVPFDSPAPQRRVLLVTRKQFFRKKAIETLRQAVFRSGLP
CCEEEEECCCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCC
DVVMLEGEPKLA
CEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8890216 [H]