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The map label for this gene is ppa [H]

Identifier: 34498827

GI number: 34498827

Start: 3668230

End: 3668757

Strand: Direct

Name: ppa [H]

Synonym: CV_3372

Alternate gene names: 34498827

Gene position: 3668230-3668757 (Clockwise)

Preceding gene: 34498819

Following gene: 34498828

Centisome position: 77.21

GC content: 62.12

Gene sequence:

>528_bases
ATGAACCTCGCAAGCATCGGCCCGGGCAAGGACATGCCGGGCGACTTCAACGTCGTCATCGAAATCTCCGCCAACGCCGC
TCCGATCAAGTACGAATTCGACAAGGACTGGAACACGCTGGTGGTGGACCGCTTCATGGGCACCTCCATGATGTACCCGG
CCAACTACGGTTTCGTGCCGCAAACCCTGGCCGGCGACGGCGATCCGGTGGACGTGCTGGTGGTCACGCCGTTCCCGTTG
CCGCCGGGCGTGGTGGTGCGCTGCCGCGCGCTGGGCCTGATCAAGATGGAAGACGACGGCGGCGTGGACGCCAAGCTGGT
CGCCGTCCCGGTCGAGAAGCTGTGCCCGATGTACAAGTCCATCCAGAAACTGGAAGACCTGCCGGAACTGCTGCGCAACC
AGATGGTGCACTTCTTCGAGCACTACAAGGACCTGGAAAAGGGCAAGTGGGTCAAGATCCAGGGCTGGGGCACGCTGGAA
GACGCCAAGACCGAACTGGTCGAAGGCATCGAACGCTTCGGCAAGTAA

Upstream 100 bases:

>100_bases
AAACCGGCGATTATACCTTGCGGGCACAGCGCCGGCAGCTGCTGATATAATCGGCCGGTTAAACCCGTTCATCTACATCA
AACACGAAGGATTGCGCGCA

Downstream 100 bases:

>100_bases
GCTGCCTCCCGCGCGACAAACCGGCCACCTGGCCGGTTTTTTTATCGCCCGGCTGATGCTGCATTGCACAATATTCGCAT
TCCGCAGGATAATGGTTTGC

Product: inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MNLASIGPGKDMPGDFNVVIEISANAAPIKYEFDKDWNTLVVDRFMGTSMMYPANYGFVPQTLAGDGDPVDVLVVTPFPL
PPGVVVRCRALGLIKMEDDGGVDAKLVAVPVEKLCPMYKSIQKLEDLPELLRNQMVHFFEHYKDLEKGKWVKIQGWGTLE
DAKTELVEGIERFGK

Sequences:

>Translated_175_residues
MNLASIGPGKDMPGDFNVVIEISANAAPIKYEFDKDWNTLVVDRFMGTSMMYPANYGFVPQTLAGDGDPVDVLVVTPFPL
PPGVVVRCRALGLIKMEDDGGVDAKLVAVPVEKLCPMYKSIQKLEDLPELLRNQMVHFFEHYKDLEKGKWVKIQGWGTLE
DAKTELVEGIERFGK
>Mature_175_residues
MNLASIGPGKDMPGDFNVVIEISANAAPIKYEFDKDWNTLVVDRFMGTSMMYPANYGFVPQTLAGDGDPVDVLVVTPFPL
PPGVVVRCRALGLIKMEDDGGVDAKLVAVPVEKLCPMYKSIQKLEDLPELLRNQMVHFFEHYKDLEKGKWVKIQGWGTLE
DAKTELVEGIERFGK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=172, Percent_Identity=61.046511627907, Blast_Score=221, Evalue=3e-59,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19474; Mature: 19474

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLASIGPGKDMPGDFNVVIEISANAAPIKYEFDKDWNTLVVDRFMGTSMMYPANYGFVP
CCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCEEEEHHHHCCEEECCCCCCCCC
QTLAGDGDPVDVLVVTPFPLPPGVVVRCRALGLIKMEDDGGVDAKLVAVPVEKLCPMYKS
HHHCCCCCCEEEEEECCCCCCCCCEEEEEECEEEEECCCCCCCEEEEEECHHHHHHHHHH
IQKLEDLPELLRNQMVHFFEHYKDLEKGKWVKIQGWGTLEDAKTELVEGIERFGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLASIGPGKDMPGDFNVVIEISANAAPIKYEFDKDWNTLVVDRFMGTSMMYPANYGFVP
CCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCEEEEHHHHCCEEECCCCCCCCC
QTLAGDGDPVDVLVVTPFPLPPGVVVRCRALGLIKMEDDGGVDAKLVAVPVEKLCPMYKS
HHHCCCCCCEEEEEECCCCCCCCCEEEEEECEEEEECCCCCCCEEEEEECHHHHHHHHHH
IQKLEDLPELLRNQMVHFFEHYKDLEKGKWVKIQGWGTLEDAKTELVEGIERFGK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]