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The map label for this gene is hlyB [H]

Identifier: 34498775

GI number: 34498775

Start: 3615281

End: 3617266

Strand: Direct

Name: hlyB [H]

Synonym: CV_3320

Alternate gene names: 34498775

Gene position: 3615281-3617266 (Clockwise)

Preceding gene: 34498772

Following gene: 34498776

Centisome position: 76.09

GC content: 66.77

Gene sequence:

>1986_bases
ATGTTGTCGAGGCTGTCCATCGCCAGCAAACTGCTGCTGTTGCTATTGCCCTTTTCCCTGGCCCTGGTAGGACTCGCCAG
CATCCTGTCGCTGGACCGCCAGCAAACGCTGAATGAGCTGCGGCGCTCGGACCGGCTGATTTCCATCGCCGGCGGCTCCA
GCCAACTGATACACGACCTGCAAACCGAACGCGGCCTCAGCAACGGCTTTCTCAGCGGCCAGGCCGCCTCGTTGCCGCCT
CCGCTGCAGGCGGCGCGCGCCAACAGCGACAAATCGCTGGCCGCCTTTACCGCCGTCAGCGGCGAACTGGGCGACAGCCG
GCTGAGCGAGCGGCTGGGCGCGCTGAACGGCCAGCTGCAGGGGCTGGCTCAGTTGCGCGCCGATGTCGAGAAACGCGGCA
TCGCGGCGCCGGACGCCTTTTCATCCTACTCCAAGGACATCGACGCGCTGATCGGGCTGATCGCCCGCCTGGCGCAGGCC
AACAACGACGGCGACCTGCTGCGCAGCACCATGGCTCTGCTCAACCTGCAGTGCGAAAAGGAATTCGCGGGGCGGGAGCG
GGGCTATGTCAACGGCTTGCTGCAGGCCGGCGTGCTCAACCAGCAAAGCCACGCGCAGGCGGCCAGCCTGATCGCCAAGC
AGGACGCCTGCGCCAACCAGTTCAAGCTGATCGCCGACGATACCCTGCGCGGCCAGAAGGAAGCGCTGGACGGCGGCGAC
GAAACCCGCGCGGTGCAAGCCTTGCGCGCCAAGGTGATGAACCAGGCGCTGGGCCAGCCGGTGGGCGTTCCGCCGGCCGA
ATGGTTCCAGGCCACCACCAGGCGCATCGACGCGCTGAAGGGCGAGCAGGATCAATTGCTGCAACAGATGGCGCAGATGG
TGGCGGTCAAGGTGGCGGCGGCCCGCTCCGACCTGATGCTGACGCTCGGCGGTTCGGCGCTGGTCATCCTGCTGCTGGGC
AGCCTGGGCTTCGCCATCTACCGCGGCATCCACATGCCGGTGCAGCGCCTGGAAGCGCTGATGACGACGATGAGCCAGGA
CTTCGATCTGAGGCCGCGCGCGACGATCCGGGGCCACGACGAGATTTCCCGCATGGGCCACGCTTTCGACCATCTGGTGG
ACGCCTTCGCCCACACGCTGAACGAGGTCAACCGCAACGCCCACACCCTGGTGGACGCCGCCAACAGCATGCTGAACATC
GCCGAGCGGGCGGCCAAGGCATCGGAAACGCAAAGCCAGTCGGCGACCGAAATCGCCGCCGCCGTCGAGCAGATGACCGC
CGGTATCGAATCGGTCACCAGCAACACCCAGCAATCGCTGACCCTGGCCCAGCAGATGCAGCGCAGCGTCCACGACGGAC
GCGAGCGCATGGGCGACACCACCTCGGCCATGCATCAGACTTCTTCGGTGCTCGACGACGCGGGCAACCGCATCGAATCG
CTGCAGCGGAAATCGGAGGACATCCGCTCCATCATCACCGCCATCCGCGAGATTGCCGATCAAACCAACCTGCTGGCGCT
GAATGCCGCGATCGAGGCGGCGCGCGCCGGCGAAATGGGCCGCGGCTTCGCCGTCGTGGCCGACGAGGTGCGCAAGCTGG
CCGAACGCACCGGCAAGGAAACGCTGGACATCACGGCGCTGATCGAGGACATCCGCGGCGAGACGCAGACCGCGGCCCAC
CACATGCAGGAGGCGCAGGAAAGGATGGAGTCCGGCCTGCAGATGGTCAGCCGGACCGTGGACGATCTGGAGCAGATACA
CAGCGAAGCCGGCCACGCGGCCAGCAAGAGCCAGGATACCGCCACCGCGATGGCCGAGCAGACTTCGGCCAGCAACGAGG
TGGCCACCAACATCAGCGTCATCGCCTCGCTGGCCGAGGACAACGCCTCCCTGGTGCAGGAGGTGGCCAAGCTGTCCGAC
CGGCTGAACGCGTCGGCCGGGGAACTGGTGCGCCTGGTGGACCGCTTCAAGCACCTCGCGGATTGA

Upstream 100 bases:

>100_bases
TTAAACGACAGTCTGCCTGGATGGCAACTTCGCCTATAGTGAAATCCGGCATGCGAGTCAGCGCCATTCAGATCCCACCA
TCCCCGAAAGGGAGAACGAC

Downstream 100 bases:

>100_bases
TCCTGCCATGCCCCGCCGTTTGAAACTGGTCCACAGGCTGGTGCTGCTCACCGCGCCGCTTGCCCTGCTGCTGCTCGCCG
GCGGCGGCGCCTACACTGTC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MLSRLSIASKLLLLLLPFSLALVGLASILSLDRQQTLNELRRSDRLISIAGGSSQLIHDLQTERGLSNGFLSGQAASLPP
PLQAARANSDKSLAAFTAVSGELGDSRLSERLGALNGQLQGLAQLRADVEKRGIAAPDAFSSYSKDIDALIGLIARLAQA
NNDGDLLRSTMALLNLQCEKEFAGRERGYVNGLLQAGVLNQQSHAQAASLIAKQDACANQFKLIADDTLRGQKEALDGGD
ETRAVQALRAKVMNQALGQPVGVPPAEWFQATTRRIDALKGEQDQLLQQMAQMVAVKVAAARSDLMLTLGGSALVILLLG
SLGFAIYRGIHMPVQRLEALMTTMSQDFDLRPRATIRGHDEISRMGHAFDHLVDAFAHTLNEVNRNAHTLVDAANSMLNI
AERAAKASETQSQSATEIAAAVEQMTAGIESVTSNTQQSLTLAQQMQRSVHDGRERMGDTTSAMHQTSSVLDDAGNRIES
LQRKSEDIRSIITAIREIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRKLAERTGKETLDITALIEDIRGETQTAAH
HMQEAQERMESGLQMVSRTVDDLEQIHSEAGHAASKSQDTATAMAEQTSASNEVATNISVIASLAEDNASLVQEVAKLSD
RLNASAGELVRLVDRFKHLAD

Sequences:

>Translated_661_residues
MLSRLSIASKLLLLLLPFSLALVGLASILSLDRQQTLNELRRSDRLISIAGGSSQLIHDLQTERGLSNGFLSGQAASLPP
PLQAARANSDKSLAAFTAVSGELGDSRLSERLGALNGQLQGLAQLRADVEKRGIAAPDAFSSYSKDIDALIGLIARLAQA
NNDGDLLRSTMALLNLQCEKEFAGRERGYVNGLLQAGVLNQQSHAQAASLIAKQDACANQFKLIADDTLRGQKEALDGGD
ETRAVQALRAKVMNQALGQPVGVPPAEWFQATTRRIDALKGEQDQLLQQMAQMVAVKVAAARSDLMLTLGGSALVILLLG
SLGFAIYRGIHMPVQRLEALMTTMSQDFDLRPRATIRGHDEISRMGHAFDHLVDAFAHTLNEVNRNAHTLVDAANSMLNI
AERAAKASETQSQSATEIAAAVEQMTAGIESVTSNTQQSLTLAQQMQRSVHDGRERMGDTTSAMHQTSSVLDDAGNRIES
LQRKSEDIRSIITAIREIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRKLAERTGKETLDITALIEDIRGETQTAAH
HMQEAQERMESGLQMVSRTVDDLEQIHSEAGHAASKSQDTATAMAEQTSASNEVATNISVIASLAEDNASLVQEVAKLSD
RLNASAGELVRLVDRFKHLAD
>Mature_661_residues
MLSRLSIASKLLLLLLPFSLALVGLASILSLDRQQTLNELRRSDRLISIAGGSSQLIHDLQTERGLSNGFLSGQAASLPP
PLQAARANSDKSLAAFTAVSGELGDSRLSERLGALNGQLQGLAQLRADVEKRGIAAPDAFSSYSKDIDALIGLIARLAQA
NNDGDLLRSTMALLNLQCEKEFAGRERGYVNGLLQAGVLNQQSHAQAASLIAKQDACANQFKLIADDTLRGQKEALDGGD
ETRAVQALRAKVMNQALGQPVGVPPAEWFQATTRRIDALKGEQDQLLQQMAQMVAVKVAAARSDLMLTLGGSALVILLLG
SLGFAIYRGIHMPVQRLEALMTTMSQDFDLRPRATIRGHDEISRMGHAFDHLVDAFAHTLNEVNRNAHTLVDAANSMLNI
AERAAKASETQSQSATEIAAAVEQMTAGIESVTSNTQQSLTLAQQMQRSVHDGRERMGDTTSAMHQTSSVLDDAGNRIES
LQRKSEDIRSIITAIREIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRKLAERTGKETLDITALIEDIRGETQTAAH
HMQEAQERMESGLQMVSRTVDDLEQIHSEAGHAASKSQDTATAMAEQTSASNEVATNISVIASLAEDNASLVQEVAKLSD
RLNASAGELVRLVDRFKHLAD

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=293, Percent_Identity=31.0580204778157, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788195, Length=278, Percent_Identity=31.294964028777, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788194, Length=312, Percent_Identity=31.0897435897436, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787690, Length=361, Percent_Identity=29.9168975069252, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789453, Length=246, Percent_Identity=30.8943089430894, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 70947; Mature: 70947

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50885 HAMP ; PS50906 NIT ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRLSIASKLLLLLLPFSLALVGLASILSLDRQQTLNELRRSDRLISIAGGSSQLIHDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHH
QTERGLSNGFLSGQAASLPPPLQAARANSDKSLAAFTAVSGELGDSRLSERLGALNGQLQ
HHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GLAQLRADVEKRGIAAPDAFSSYSKDIDALIGLIARLAQANNDGDLLRSTMALLNLQCEK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EFAGRERGYVNGLLQAGVLNQQSHAQAASLIAKQDACANQFKLIADDTLRGQKEALDGGD
HHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCH
ETRAVQALRAKVMNQALGQPVGVPPAEWFQATTRRIDALKGEQDQLLQQMAQMVAVKVAA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ARSDLMLTLGGSALVILLLGSLGFAIYRGIHMPVQRLEALMTTMSQDFDLRPRATIRGHD
HHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
EISRMGHAFDHLVDAFAHTLNEVNRNAHTLVDAANSMLNIAERAAKASETQSQSATEIAA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVEQMTAGIESVTSNTQQSLTLAQQMQRSVHDGRERMGDTTSAMHQTSSVLDDAGNRIES
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LQRKSEDIRSIITAIREIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRKLAERTGKE
HHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
TLDITALIEDIRGETQTAAHHMQEAQERMESGLQMVSRTVDDLEQIHSEAGHAASKSQDT
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
ATAMAEQTSASNEVATNISVIASLAEDNASLVQEVAKLSDRLNASAGELVRLVDRFKHLA
HHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
D
C
>Mature Secondary Structure
MLSRLSIASKLLLLLLPFSLALVGLASILSLDRQQTLNELRRSDRLISIAGGSSQLIHDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHH
QTERGLSNGFLSGQAASLPPPLQAARANSDKSLAAFTAVSGELGDSRLSERLGALNGQLQ
HHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GLAQLRADVEKRGIAAPDAFSSYSKDIDALIGLIARLAQANNDGDLLRSTMALLNLQCEK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EFAGRERGYVNGLLQAGVLNQQSHAQAASLIAKQDACANQFKLIADDTLRGQKEALDGGD
HHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCH
ETRAVQALRAKVMNQALGQPVGVPPAEWFQATTRRIDALKGEQDQLLQQMAQMVAVKVAA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ARSDLMLTLGGSALVILLLGSLGFAIYRGIHMPVQRLEALMTTMSQDFDLRPRATIRGHD
HHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
EISRMGHAFDHLVDAFAHTLNEVNRNAHTLVDAANSMLNIAERAAKASETQSQSATEIAA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVEQMTAGIESVTSNTQQSLTLAQQMQRSVHDGRERMGDTTSAMHQTSSVLDDAGNRIES
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LQRKSEDIRSIITAIREIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRKLAERTGKE
HHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
TLDITALIEDIRGETQTAAHHMQEAQERMESGLQMVSRTVDDLEQIHSEAGHAASKSQDT
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
ATAMAEQTSASNEVATNISVIASLAEDNASLVQEVAKLSDRLNASAGELVRLVDRFKHLA
HHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]