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The map label for this gene is actP [H]

Identifier: 34498736

GI number: 34498736

Start: 3571315

End: 3572994

Strand: Direct

Name: actP [H]

Synonym: CV_3281

Alternate gene names: 34498736

Gene position: 3571315-3572994 (Clockwise)

Preceding gene: 34498735

Following gene: 34498737

Centisome position: 75.17

GC content: 65.0

Gene sequence:

>1680_bases
ATGCAGCAAATCCGACTCAAACTCGCCGCCTGCTCGGCGGCGCTGCTGCCCGCGCTCGCCTGCGCGGCCGGCGCGATAGA
AGGCGACGTCAAGCAGCAAGCCACCAACTGGCACGCCATCATCATGTTCTTCCTGTTCGTCGCCTTCACGCTGGGCATCA
CCTACTGGGCGGCGCGCCGCACCAAGTCGGCCAGCGACTTCTACGCCGCGGGCGGCGGCATCACCGGCTTCCAGAACGGC
CTGGCGATCGCCGGTGACTATATGTCCGCCGCGTCCTTCCTGGGGATTTCCGCGCTGGTGTTCGAAAAGGGCTACGACGG
CCTGATCTACTCGATGGGCTTCCTGGTCGGCTGGCCCATCATCCTGTTCCTGGTGGCCGAACGGCTGCGCAACCTGGGCA
AGTACACCTTCGCAGACGTCGCCTCCTACCGGCTCGGACAGACGCCGGTGCGCAGCTTCGCCGCGCTGTCCACGCTGGTG
GTGGTGGCGATCTACCTGATCGCCCAGATGGTCGGCGCGGGCAAGCTGATCCAGCTCTTGTTCGGCATGAGCTACAGCTC
CGCCGTGCTGATGGTCGGCGTGCTGATGGTGTGCTACGTGCTGTTCGGCGGCATGCTGGCCACCACCTGGGTGCAAATCA
TCAAGGCGGTGCTGCTGCTGTCCGGCGCCACCTTCATGGCCATCATGGTGCTGTCCACCGTCGGTTTCAGCCCGGAAATG
ATGTTCGAGAAAGCCGTGGCCGCGCACAGCAAGGGCGCCGCCATCATGGCGCCGGGCAAGGCGGACCCGATCGACTCCAT
CTCGCTGGGCCTGGCGCTGATGTTCGGCACCGCCGGCCTGCCGCACATCCTGATGCGCTTCTTCACTGTCGCCGACGCCA
AGGAAGCCCGCAAATCGGTGTTCTTCGCCACCGGTTTCATCGGCTACTTCTACATCCTGACCTTCATCATCGGCTTCGGC
GCCATCATGCTGGTGCTGAACCAGCCGGGCATGATGGAAACCGTGGTCAAGAACGGCAAGTCGGTCACCCAGCTGATCGG
CGGCAACAATATGGCCGCCATCCACCTGGCCGACGCCGTCGGCGGCGACATCTTCCTCGGCTTCATCTCCGCGGTGGCCT
TCGCCACCATCCTGGCGGTGGTGGCGGGCCTGGCGCTGTCCGGCGCGTCCGCGGTGTCGCACGATCTGTACGCCAGCGTG
ATCAAGCACGGCAAGGCCAACGAGGCCGACGAGATCCGCGTGTCCAAGATCACCACCGTGGTGCTGGGCGTGGTGGCCAT
CGTGCTGGGCCTGGTGTTCGAGAAGCAGAACATCGCCTTCATGGTCGGCCTCGCCTTCTCCATCGCCGCCTCCGCCAACT
TCCCGGTGCTGTTCCTGTCCATGTTTTGGAAGGGCCTGACCACGCGCGGCGCGGTGGTGGGCGGCCTGGTCGGCCTGCTG
ACCGCGGTGGTGCTGATCGTGCTGGGACCGACGGTGTGGGTGGAAGTGATGAAGCACGAGCACGCCATCTTCCCGTACAA
GAACCCGGCCATCTTCTCGATGACCCTGGCCTTCGTCGTCACCTGGCTGGTTTCGGTGCTGGACACCTCCAAGCAGGCCG
CAGACGAGAAGGCCAAGTTCGAGGCCCAGTACGTGCGGGCGATGACCGGCATCGGCGCCAGTGGCGCCAGCAAGCACTAA

Upstream 100 bases:

>100_bases
GCATCATCCTGTCGGCCTTCGTGCTGACCGGCATCTACGTGCGCCGCGCCAACCAGGAATTCGACCCATTGACCCAGCAG
ATCGTCGAGGAGGCCAAGTG

Downstream 100 bases:

>100_bases
ATGTCATCATCATTGACATGCCGCGCGCCGGATGACGCGCGGCGATAACACCGAAAAGACTCTGGAGAAACACGTATGTC
GACGCTAGATTCCATCCTCA

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MQQIRLKLAACSAALLPALACAAGAIEGDVKQQATNWHAIIMFFLFVAFTLGITYWAARRTKSASDFYAAGGGITGFQNG
LAIAGDYMSAASFLGISALVFEKGYDGLIYSMGFLVGWPIILFLVAERLRNLGKYTFADVASYRLGQTPVRSFAALSTLV
VVAIYLIAQMVGAGKLIQLLFGMSYSSAVLMVGVLMVCYVLFGGMLATTWVQIIKAVLLLSGATFMAIMVLSTVGFSPEM
MFEKAVAAHSKGAAIMAPGKADPIDSISLGLALMFGTAGLPHILMRFFTVADAKEARKSVFFATGFIGYFYILTFIIGFG
AIMLVLNQPGMMETVVKNGKSVTQLIGGNNMAAIHLADAVGGDIFLGFISAVAFATILAVVAGLALSGASAVSHDLYASV
IKHGKANEADEIRVSKITTVVLGVVAIVLGLVFEKQNIAFMVGLAFSIAASANFPVLFLSMFWKGLTTRGAVVGGLVGLL
TAVVLIVLGPTVWVEVMKHEHAIFPYKNPAIFSMTLAFVVTWLVSVLDTSKQAADEKAKFEAQYVRAMTGIGASGASKH

Sequences:

>Translated_559_residues
MQQIRLKLAACSAALLPALACAAGAIEGDVKQQATNWHAIIMFFLFVAFTLGITYWAARRTKSASDFYAAGGGITGFQNG
LAIAGDYMSAASFLGISALVFEKGYDGLIYSMGFLVGWPIILFLVAERLRNLGKYTFADVASYRLGQTPVRSFAALSTLV
VVAIYLIAQMVGAGKLIQLLFGMSYSSAVLMVGVLMVCYVLFGGMLATTWVQIIKAVLLLSGATFMAIMVLSTVGFSPEM
MFEKAVAAHSKGAAIMAPGKADPIDSISLGLALMFGTAGLPHILMRFFTVADAKEARKSVFFATGFIGYFYILTFIIGFG
AIMLVLNQPGMMETVVKNGKSVTQLIGGNNMAAIHLADAVGGDIFLGFISAVAFATILAVVAGLALSGASAVSHDLYASV
IKHGKANEADEIRVSKITTVVLGVVAIVLGLVFEKQNIAFMVGLAFSIAASANFPVLFLSMFWKGLTTRGAVVGGLVGLL
TAVVLIVLGPTVWVEVMKHEHAIFPYKNPAIFSMTLAFVVTWLVSVLDTSKQAADEKAKFEAQYVRAMTGIGASGASKH
>Mature_559_residues
MQQIRLKLAACSAALLPALACAAGAIEGDVKQQATNWHAIIMFFLFVAFTLGITYWAARRTKSASDFYAAGGGITGFQNG
LAIAGDYMSAASFLGISALVFEKGYDGLIYSMGFLVGWPIILFLVAERLRNLGKYTFADVASYRLGQTPVRSFAALSTLV
VVAIYLIAQMVGAGKLIQLLFGMSYSSAVLMVGVLMVCYVLFGGMLATTWVQIIKAVLLLSGATFMAIMVLSTVGFSPEM
MFEKAVAAHSKGAAIMAPGKADPIDSISLGLALMFGTAGLPHILMRFFTVADAKEARKSVFFATGFIGYFYILTFIIGFG
AIMLVLNQPGMMETVVKNGKSVTQLIGGNNMAAIHLADAVGGDIFLGFISAVAFATILAVVAGLALSGASAVSHDLYASV
IKHGKANEADEIRVSKITTVVLGVVAIVLGLVFEKQNIAFMVGLAFSIAASANFPVLFLSMFWKGLTTRGAVVGGLVGLL
TAVVLIVLGPTVWVEVMKHEHAIFPYKNPAIFSMTLAFVVTWLVSVLDTSKQAADEKAKFEAQYVRAMTGIGASGASKH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=536, Percent_Identity=22.9477611940299, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1790503, Length=549, Percent_Identity=69.2167577413479, Blast_Score=758, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=457, Percent_Identity=25.601750547046, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87082237, Length=447, Percent_Identity=22.8187919463087, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 59085; Mature: 59085

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA