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The map label for this gene is ebrB [C]

Identifier: 34498698

GI number: 34498698

Start: 3522610

End: 3524007

Strand: Direct

Name: ebrB [C]

Synonym: CV_3243

Alternate gene names: 34498698

Gene position: 3522610-3524007 (Clockwise)

Preceding gene: 34498697

Following gene: 34498700

Centisome position: 74.14

GC content: 73.89

Gene sequence:

>1398_bases
ATGCAGCCATCCGTCAACAACGAAAGTCTCTTCAGCCAGGGCAGAACCGCGGCCTGCATCGGCGGCATCGCGCTGATCTC
GCTGCTGGCCTTCGAATCCATCGCCGTCGCCGCGGCCATGCCCGCCGTCGCCGCCGCGCTGGGCGGCCTGGATTTTTACG
CCATCGCCTTCGGCGGCACGCTGGCCACCTCGGTGGCGGGCATGACGCTGGGCGGCGAGATCTGCGACCGCTACGGCGCG
GCCCGCTCCGCCTGGCTGGGCCTGGCCGCCTTCATCGCCGGCCTGCTGGCGGCGGGCGCGGCGTCCGACATGTACACGCT
GGTGCTGGGGCGGCTGATGCAGGGGCTGGGCTCCGGCCTGCTGGGCGTGGCCATCTACGTGGGCATGTCGCGCGCGGTGC
CGCCCGCGCTGCATCCCAAGCTGTTCGCGATGTTCGCCGGCGCCTGGGTGGTGCCCGCGCTGATCGGCCCCGGCATCGCC
GCCGGCCTGGTCCACATCTTCGGCTGGCGCGCGGTGTTCCTAGCGGTGGCGGCGCTGGCGCCGGTCGCCGGCGCGCTGCT
GCTGCCCGCCCTGAGCCGGCAGGAGGCGCCGGCCGGCGCCGCCAAGCCGATGCGCTGGCGACGCCTGGGCTGGAGCCTGC
TGGCCGCCAGCGGCGCGCTGGCGCTGCACGGCGGCAGCCATCTGCCGCAAACGCAATACATATTGCCGATGCTGGCGGCC
GGCTTCGCCCTCGCCTTTTTCGCGGCGCGCCGTCTGTTGCCCGCCGGCAGCCTGCGCGCCGCCGAAGGCCTGCCCTCGGT
GGTGGCGATGCGCGGCCTCATCGCCGCCGCCTTCTTCGCCAGCGAGGCCTTTGTCCCGCTGATCCTGACCACCCGCTACC
ACTGGAGCCTGGGGTCGGCCGGCCTGGCGCTCACCGCCAGCGCGGTGATGTGGAGCCTAGGCAGCGCCACCCAGACGCGG
CTGCGCGGCGACGCCGCCCGCCGCCGCGGACTGACCCTGGGCTTCGCCGCGATGGGCGCCGGCCTGTGCTTCGCGCTGGG
CGCGGCCAGCCTGTCGCTGCACGCCGGATGGGTGGTAGCCGGCTGGGCGGTGACCGGCTTAGGGATAGGCCTGAGCTTCC
CGATGCTGTCGGTGCTGACGATGAAGCTGTCCCGGCCGGACGAGCAAGGCAGCAACGCCTCGGCGCTGCAGTTGAGCGAC
GCGCTGTCTTCCAGCATCGCGCTGGCGCTGGCCGGTTTGCTGATCCACGCGCTGTCGCGTCCGTCCGCGCCGCCGGACGC
GCTGCCCATCCTGGCGATGTCGGCGCTGCTGGCGCTGATCGGCGCCTGGGTCAGCCCGCGGGCGTTCGCCTCCGCCGCGC
CGGCCCGCGCGGAAGCCGGAGCGGGTCAGCTGTCGTAA

Upstream 100 bases:

>100_bases
GCCGGCCGGATGCCATGCTGCGGCCGTACGCGCAGGCTCTTGACTTCAAGTTAACTTTAACTTTCATCATGACGGCTCCT
ACCGCTACAAGAGTTTCCCC

Downstream 100 bases:

>100_bases
GCGCCCGGCGGCCCCTGGCCGTCACAGCGCCTGCGGATCGATGTCGGCCACGCTGTCGAACACGTAGTCCGGCTGGTAGG
GAAATTGCTCCATCGATGCG

Product: transmembrane multidrug resistance efflux protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: Facilitator Transporter; Facilitator Superfamily Protein; Facilitator Superfamily Transporter; MFS Transporter; Facilitator Superfamily Permease; Arabinose Efflux Permease Family Protein; Multidrug Efflux Transporter; Facilitator Superfamily Transmembrane Transporter Protein; Transmembrane Multidrug Resistance Efflux Protein; Facilitator Superfamily Transporter Permease; Permease Of Facilitator Superfamily; Transmembrane Transporter

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MQPSVNNESLFSQGRTAACIGGIALISLLAFESIAVAAAMPAVAAALGGLDFYAIAFGGTLATSVAGMTLGGEICDRYGA
ARSAWLGLAAFIAGLLAAGAASDMYTLVLGRLMQGLGSGLLGVAIYVGMSRAVPPALHPKLFAMFAGAWVVPALIGPGIA
AGLVHIFGWRAVFLAVAALAPVAGALLLPALSRQEAPAGAAKPMRWRRLGWSLLAASGALALHGGSHLPQTQYILPMLAA
GFALAFFAARRLLPAGSLRAAEGLPSVVAMRGLIAAAFFASEAFVPLILTTRYHWSLGSAGLALTASAVMWSLGSATQTR
LRGDAARRRGLTLGFAAMGAGLCFALGAASLSLHAGWVVAGWAVTGLGIGLSFPMLSVLTMKLSRPDEQGSNASALQLSD
ALSSSIALALAGLLIHALSRPSAPPDALPILAMSALLALIGAWVSPRAFASAAPARAEAGAGQLS

Sequences:

>Translated_465_residues
MQPSVNNESLFSQGRTAACIGGIALISLLAFESIAVAAAMPAVAAALGGLDFYAIAFGGTLATSVAGMTLGGEICDRYGA
ARSAWLGLAAFIAGLLAAGAASDMYTLVLGRLMQGLGSGLLGVAIYVGMSRAVPPALHPKLFAMFAGAWVVPALIGPGIA
AGLVHIFGWRAVFLAVAALAPVAGALLLPALSRQEAPAGAAKPMRWRRLGWSLLAASGALALHGGSHLPQTQYILPMLAA
GFALAFFAARRLLPAGSLRAAEGLPSVVAMRGLIAAAFFASEAFVPLILTTRYHWSLGSAGLALTASAVMWSLGSATQTR
LRGDAARRRGLTLGFAAMGAGLCFALGAASLSLHAGWVVAGWAVTGLGIGLSFPMLSVLTMKLSRPDEQGSNASALQLSD
ALSSSIALALAGLLIHALSRPSAPPDALPILAMSALLALIGAWVSPRAFASAAPARAEAGAGQLS
>Mature_465_residues
MQPSVNNESLFSQGRTAACIGGIALISLLAFESIAVAAAMPAVAAALGGLDFYAIAFGGTLATSVAGMTLGGEICDRYGA
ARSAWLGLAAFIAGLLAAGAASDMYTLVLGRLMQGLGSGLLGVAIYVGMSRAVPPALHPKLFAMFAGAWVVPALIGPGIA
AGLVHIFGWRAVFLAVAALAPVAGALLLPALSRQEAPAGAAKPMRWRRLGWSLLAASGALALHGGSHLPQTQYILPMLAA
GFALAFFAARRLLPAGSLRAAEGLPSVVAMRGLIAAAFFASEAFVPLILTTRYHWSLGSAGLALTASAVMWSLGSATQTR
LRGDAARRRGLTLGFAAMGAGLCFALGAASLSLHAGWVVAGWAVTGLGIGLSFPMLSVLTMKLSRPDEQGSNASALQLSD
ALSSSIALALAGLLIHALSRPSAPPDALPILAMSALLALIGAWVSPRAFASAAPARAEAGAGQLS

Specific function: Efflux Pump Driven By The Proton Motive Force. Confers Resistance To Basic, Aromatic And Lipophilic Drugs As Well As Neutral, Non-Aromatic, Zwitterionic Or Nonaromatic Hydrophilic Antibiotics. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46837; Mature: 46837

Theoretical pI: Translated: 11.02; Mature: 11.02

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHCCCCCCCC
>Mature Secondary Structure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CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA