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The map label for this gene is trh1 [H]

Identifier: 34498667

GI number: 34498667

Start: 3493461

End: 3493850

Strand: Direct

Name: trh1 [H]

Synonym: CV_3212

Alternate gene names: 34498667

Gene position: 3493461-3493850 (Clockwise)

Preceding gene: 34498666

Following gene: 34498668

Centisome position: 73.53

GC content: 64.87

Gene sequence:

>390_bases
ATGACCATAGAAAAAACCGACGCCGAATGGCGCGCGCAACTGACGTCGGAGCAATACCGCGTGGCGCGTCAAGCCGGCAC
CGAGCGCCCCTTCAGCGGCGAACACTACTTCCACAACAAGAAGGGCGACTATTTCTGCGTCTGCTGCGGCACGCTGCTGT
TCCACAGCGACACCAAGTTCGACGCCGGCTGCGGCTGGCCCAGCTTCTGGGCCGAAGCCGCCGGCGCCAACATCGCCCGC
CTCACCGACACCACCCACGGCATGGTGCGCGTAGAGGTCCGCTGCTCGCATTGCGACGCCCACCTCGGCCACGTGTTCGA
GGACGGCCCGGAACCGACCGGCGAGCGCTACTGCATCAACTCGGTGTGCCTGGATTTCAAGGCGGAGTAA

Upstream 100 bases:

>100_bases
CCGGCGGGAATTTGTTAGTCTCCGGTAAGAAAGCCGCCCGCGCGGCGACCAACCATCAAGCGCTCGGCCCGCCGGGCTGG
ACGACACAAGGACACCCGCC

Downstream 100 bases:

>100_bases
GACCGGTTATGTAGGTTTTCAGAGTTATTGAAAACTCTGTGCACATAGTCGAAATTGCACCAACATAGGGCATAGCTCTT
ACTCGCTATGCCTTTAGTTA

Product: transcriptional regulator

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MTIEKTDAEWRAQLTSEQYRVARQAGTERPFSGEHYFHNKKGDYFCVCCGTLLFHSDTKFDAGCGWPSFWAEAAGANIAR
LTDTTHGMVRVEVRCSHCDAHLGHVFEDGPEPTGERYCINSVCLDFKAE

Sequences:

>Translated_129_residues
MTIEKTDAEWRAQLTSEQYRVARQAGTERPFSGEHYFHNKKGDYFCVCCGTLLFHSDTKFDAGCGWPSFWAEAAGANIAR
LTDTTHGMVRVEVRCSHCDAHLGHVFEDGPEPTGERYCINSVCLDFKAE
>Mature_128_residues
TIEKTDAEWRAQLTSEQYRVARQAGTERPFSGEHYFHNKKGDYFCVCCGTLLFHSDTKFDAGCGWPSFWAEAAGANIARL
TDTTHGMVRVEVRCSHCDAHLGHVFEDGPEPTGERYCINSVCLDFKAE

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=121, Percent_Identity=52.8925619834711, Blast_Score=134, Evalue=3e-32,
Organism=Homo sapiens, GI301336162, Length=121, Percent_Identity=52.8925619834711, Blast_Score=134, Evalue=3e-32,
Organism=Homo sapiens, GI73089054, Length=121, Percent_Identity=52.8925619834711, Blast_Score=134, Evalue=3e-32,
Organism=Homo sapiens, GI37620216, Length=121, Percent_Identity=52.8925619834711, Blast_Score=134, Evalue=3e-32,
Organism=Homo sapiens, GI117606353, Length=128, Percent_Identity=50.78125, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI1788077, Length=126, Percent_Identity=48.4126984126984, Blast_Score=141, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17553450, Length=125, Percent_Identity=60, Blast_Score=151, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI115532676, Length=124, Percent_Identity=60.4838709677419, Blast_Score=151, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319816, Length=135, Percent_Identity=39.2592592592593, Blast_Score=99, Evalue=1e-22,
Organism=Drosophila melanogaster, GI221378662, Length=126, Percent_Identity=50, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI221378664, Length=119, Percent_Identity=51.2605042016807, Blast_Score=129, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24645799, Length=119, Percent_Identity=49.5798319327731, Blast_Score=127, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24645801, Length=131, Percent_Identity=48.0916030534351, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI45553335, Length=119, Percent_Identity=49.5798319327731, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21356369, Length=119, Percent_Identity=49.5798319327731, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24645804, Length=131, Percent_Identity=48.0916030534351, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 14527; Mature: 14396

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
6.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIEKTDAEWRAQLTSEQYRVARQAGTERPFSGEHYFHNKKGDYFCVCCGTLLFHSDTKF
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEEEECHHHHCCCCCC
DAGCGWPSFWAEAAGANIARLTDTTHGMVRVEVRCSHCDAHLGHVFEDGPEPTGERYCIN
CCCCCCHHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCHHCHHHCCCCCCCCCEEEEH
SVCLDFKAE
HEEEEECCC
>Mature Secondary Structure 
TIEKTDAEWRAQLTSEQYRVARQAGTERPFSGEHYFHNKKGDYFCVCCGTLLFHSDTKF
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEEEECHHHHCCCCCC
DAGCGWPSFWAEAAGANIARLTDTTHGMVRVEVRCSHCDAHLGHVFEDGPEPTGERYCIN
CCCCCCHHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCHHCHHHCCCCCCCCCEEEEH
SVCLDFKAE
HEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]