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The map label for this gene is lolC [H]

Identifier: 34498419

GI number: 34498419

Start: 3243049

End: 3244287

Strand: Reverse

Name: lolC [H]

Synonym: CV_2964

Alternate gene names: 34498419

Gene position: 3244287-3243049 (Counterclockwise)

Preceding gene: 34498420

Following gene: 34498418

Centisome position: 68.29

GC content: 66.42

Gene sequence:

>1239_bases
ATGCCATTTGAAGCCTTCATCGGGCTGCGCTATCTGCGCGCCAAGCGCCGCAACGGATTCATCTCTTTCATCTCCCTGAT
TTCCATCGTCGGCATCGCGCTGGGCGTAGCCGCGCTGATCATCGTGCTGTCGGTGATGAACGGTTTCCAGAAGGAAATCC
GCGGCCGCATCCTCAGCGTGGCCTCCCACTTGGAAGTCAGCGGCTACGACGGCCGCCTGTCCGGCTGGCGAGACGCGCAG
GCGATGCTGGCCAAGCAGCCGCACGTGCAGGCGGCGGCGCCCTTCGTCAGCAGCCAGGGCCTGTTCGTCGCCTACGGCAA
CGTGCGCGGCGGCCTGGTGCGCGGCATCGATCCCGCGCTGGAGAACAAAGTGGTGGACGTCGGCCGCCACATGGTGGCCG
GCAAGCTGGAAGACCTGAAGCCCGGCGGCTTCGGCATGGCGCTGGGCGTGGAGCTGGCGCGCCAGCTGGGCGTCGGCGTC
GGCGACAAGGTGACGCTGATGACGCCGCAGGGCAACATCACGCCGGCCGGCATGGTGCCGCGCTCCAAGCAGTTCACCGT
GGTCGGCATCTTCAAGGTGGACATGTTCGAGTTCGACGCCTCGCTGGCCATGGTCAACCTGCGCGACGCCCAGGTGCTGG
AGCGCATGGGCGACGCGGTCAGCGGCGTGCGGCTGCGCCTGGACGACCCGATGCTGGCGCCGCAGCTGAAGGCCGAGCTG
CGGCCGCGGCTGCCGCAACTGCTGGTCACCGACTGGACCGACACCAATGCCAATTACTTCCGCGCGGTGCAGATCGAAAA
GCGGATGATGACCATCATCCTGACGCTGATCGTCGCGGTGGCGGCGTTCAACCTGGTGTCCACGCTGGTGATGGTGGTGA
CCGACAAGCAGGCCGACATCGCCATCCTGCGCACGCTGGGCGCGTCGCCGGGCAGCATCATGAAGATCTTCGTGATCCAG
GGCTCGGTGGCCGGGGTGCTGGGCACGCTGGCCGGCGTGGCCAGCGGCGTGGCCATCGCGCTGAACCTGGACGTGATCGT
GCCGGTGATCGAACGCATCATCGGCACCAAGATCCTGTCCAGCGACGTCTACATGATCGACTACCTGCCGTCCGACGTGC
AGTGGGGCGACGTCTCCACCATCACTATCATTTCGCTGCTGCTGGCCTTGTTCGCCACGCTGTACCCGAGCTGGCGCGCC
GCGCGCACCCAACCGGCGGAGGCCTTGCGCTATGAATAA

Upstream 100 bases:

>100_bases
GGTGCTGATGGGCTGCGAGGAGACGCAGGTGCGCGACTTCCTGGTGGCGATGATGCAGAGCCTGGAAAACCCCTACCGTT
CCAAATGAGAAAACCCGAAC

Downstream 100 bases:

>100_bases
GGTATTGAGCTGCCGCTCGCTCGGCAAACGCTACCAGGAGGGCAAGCTGGCGCTGGACGTGCTGTCCGGCGTCGATCTGG
AGGTGGGCAAGGGCGAGCAT

Product: lipoprotein releasing system trasmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MPFEAFIGLRYLRAKRRNGFISFISLISIVGIALGVAALIIVLSVMNGFQKEIRGRILSVASHLEVSGYDGRLSGWRDAQ
AMLAKQPHVQAAAPFVSSQGLFVAYGNVRGGLVRGIDPALENKVVDVGRHMVAGKLEDLKPGGFGMALGVELARQLGVGV
GDKVTLMTPQGNITPAGMVPRSKQFTVVGIFKVDMFEFDASLAMVNLRDAQVLERMGDAVSGVRLRLDDPMLAPQLKAEL
RPRLPQLLVTDWTDTNANYFRAVQIEKRMMTIILTLIVAVAAFNLVSTLVMVVTDKQADIAILRTLGASPGSIMKIFVIQ
GSVAGVLGTLAGVASGVAIALNLDVIVPVIERIIGTKILSSDVYMIDYLPSDVQWGDVSTITIISLLLALFATLYPSWRA
ARTQPAEALRYE

Sequences:

>Translated_412_residues
MPFEAFIGLRYLRAKRRNGFISFISLISIVGIALGVAALIIVLSVMNGFQKEIRGRILSVASHLEVSGYDGRLSGWRDAQ
AMLAKQPHVQAAAPFVSSQGLFVAYGNVRGGLVRGIDPALENKVVDVGRHMVAGKLEDLKPGGFGMALGVELARQLGVGV
GDKVTLMTPQGNITPAGMVPRSKQFTVVGIFKVDMFEFDASLAMVNLRDAQVLERMGDAVSGVRLRLDDPMLAPQLKAEL
RPRLPQLLVTDWTDTNANYFRAVQIEKRMMTIILTLIVAVAAFNLVSTLVMVVTDKQADIAILRTLGASPGSIMKIFVIQ
GSVAGVLGTLAGVASGVAIALNLDVIVPVIERIIGTKILSSDVYMIDYLPSDVQWGDVSTITIISLLLALFATLYPSWRA
ARTQPAEALRYE
>Mature_411_residues
PFEAFIGLRYLRAKRRNGFISFISLISIVGIALGVAALIIVLSVMNGFQKEIRGRILSVASHLEVSGYDGRLSGWRDAQA
MLAKQPHVQAAAPFVSSQGLFVAYGNVRGGLVRGIDPALENKVVDVGRHMVAGKLEDLKPGGFGMALGVELARQLGVGVG
DKVTLMTPQGNITPAGMVPRSKQFTVVGIFKVDMFEFDASLAMVNLRDAQVLERMGDAVSGVRLRLDDPMLAPQLKAELR
PRLPQLLVTDWTDTNANYFRAVQIEKRMMTIILTLIVAVAAFNLVSTLVMVVTDKQADIAILRTLGASPGSIMKIFVIQG
SVAGVLGTLAGVASGVAIALNLDVIVPVIERIIGTKILSSDVYMIDYLPSDVQWGDVSTITIISLLLALFATLYPSWRAA
RTQPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=410, Percent_Identity=39.5121951219512, Blast_Score=261, Evalue=5e-71,
Organism=Escherichia coli, GI1787360, Length=413, Percent_Identity=37.772397094431, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44417; Mature: 44286

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFEAFIGLRYLRAKRRNGFISFISLISIVGIALGVAALIIVLSVMNGFQKEIRGRILSV
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASHLEVSGYDGRLSGWRDAQAMLAKQPHVQAAAPFVSSQGLFVAYGNVRGGLVRGIDPAL
HHHCEECCCCCCCCCCHHHHHHHHCCCCCHHHCCCCCCCCEEEEECCCCCCCCCCCCHHH
ENKVVDVGRHMVAGKLEDLKPGGFGMALGVELARQLGVGVGDKVTLMTPQGNITPAGMVP
HHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCC
RSKQFTVVGIFKVDMFEFDASLAMVNLRDAQVLERMGDAVSGVRLRLDDPMLAPQLKAEL
CCCCEEEEEEEEEEEEHHCCCEEEEECHHHHHHHHHCCHHCCCEEEECCCCCCHHHHHHH
RPRLPQLLVTDWTDTNANYFRAVQIEKRMMTIILTLIVAVAAFNLVSTLVMVVTDKQADI
CCCCCCEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCH
AILRTLGASPGSIMKIFVIQGSVAGVLGTLAGVASGVAIALNLDVIVPVIERIIGTKILS
HHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHC
SDVYMIDYLPSDVQWGDVSTITIISLLLALFATLYPSWRAARTQPAEALRYE
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHCCC
>Mature Secondary Structure 
PFEAFIGLRYLRAKRRNGFISFISLISIVGIALGVAALIIVLSVMNGFQKEIRGRILSV
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASHLEVSGYDGRLSGWRDAQAMLAKQPHVQAAAPFVSSQGLFVAYGNVRGGLVRGIDPAL
HHHCEECCCCCCCCCCHHHHHHHHCCCCCHHHCCCCCCCCEEEEECCCCCCCCCCCCHHH
ENKVVDVGRHMVAGKLEDLKPGGFGMALGVELARQLGVGVGDKVTLMTPQGNITPAGMVP
HHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCC
RSKQFTVVGIFKVDMFEFDASLAMVNLRDAQVLERMGDAVSGVRLRLDDPMLAPQLKAEL
CCCCEEEEEEEEEEEEHHCCCEEEEECHHHHHHHHHCCHHCCCEEEECCCCCCHHHHHHH
RPRLPQLLVTDWTDTNANYFRAVQIEKRMMTIILTLIVAVAAFNLVSTLVMVVTDKQADI
CCCCCCEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCH
AILRTLGASPGSIMKIFVIQGSVAGVLGTLAGVASGVAIALNLDVIVPVIERIIGTKILS
HHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHC
SDVYMIDYLPSDVQWGDVSTITIISLLLALFATLYPSWRAARTQPAEALRYE
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]