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The map label for this gene is nudC

Identifier: 34498360

GI number: 34498360

Start: 3182301

End: 3183098

Strand: Direct

Name: nudC

Synonym: CV_2905

Alternate gene names: 34498360

Gene position: 3182301-3183098 (Clockwise)

Preceding gene: 34498359

Following gene: 34498361

Centisome position: 66.98

GC content: 68.8

Gene sequence:

>798_bases
ATGCCTTTCGAACTCCCGCAACAACCGGCGCCGGAACTGCCCGAGCGCTGGTGCGTATTCAACGGCAGCCTGCTGTGGCT
GCAGGACAATCAGCTGCCGGCGCAGCCGCCGGCCGGCTGCGCGTTGACCGGCCAGCGCTTTCTCGGCATTCACGAAGGCA
GCAACCTGTTCCTGGCGGACCTGGTCGGCGACATGCCGGCGCAGGCCGGAGAATGGCTGCCGCTGCGCCCGGCGCTGCTG
GCCATGCCCATGGCCCAGGTCCAAGCGGCCGCCCGCGCCGCCCAGCTGCGCCAGTTCTTCCACAGCCACCGCTTCTGCGG
CCATTGCGCCACGCCGCTGGCCGTCAGCGCCGACCAGCTCGGCCGGCACTGCCCCAGCTGCGGCCAGGTGTACTACCCGC
GCATCTCCCCCGCCATGATGGTGCTGGTCCGCCGCGGCCGCGAACTGCTGCTGGCCCGCAGCCCACACTTCGCGCCCGGC
ATGTACAGCGCGCTGGCCGGCTTCGTCGAGCCCGGCGAAACGCTGGAAGAATGCGTGCACCGCGAAACCTGGGAGGAAGT
GGGCGTGAAAGTGAAGAACCTGCGTTACGCCTTCTCCCAGTCCTGGCCCTTTCCGCACTCGCTGATGCTGGCCTTCATCG
CCGAATACGACGGCGGCGACATCCGCCCGCAGGAGGGAGAGATCGAGGACGCGGGCTGGTTCGACATCGACGCGCTGCCG
GGGCTGCCGATGCCCATCTCCATCGCCCATCGCCTGATCCGGCATGCCTGCGACAGAATCCGCGACCTAGAAGCGTAA

Upstream 100 bases:

>100_bases
GGCTCGCTGAGCGAGGTGGTGCGCCGCCAGAGCGAGCACTGGATGTACGCCGAGCCGGGAGTCGGCGTAAACTGAGCGAT
TGCAATCGGATCGCCCCTTT

Downstream 100 bases:

>100_bases
GCCCATGCTCACAGCCCGGAGAGGCGGGATGCCCCATCCTGCCCATCCGGCGCTCCCCATCAGGCTTCAGCGCGCCGTCT
CAAGAACAGCGACCGGCCTC

Product: NAD diphosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MPFELPQQPAPELPERWCVFNGSLLWLQDNQLPAQPPAGCALTGQRFLGIHEGSNLFLADLVGDMPAQAGEWLPLRPALL
AMPMAQVQAAARAAQLRQFFHSHRFCGHCATPLAVSADQLGRHCPSCGQVYYPRISPAMMVLVRRGRELLLARSPHFAPG
MYSALAGFVEPGETLEECVHRETWEEVGVKVKNLRYAFSQSWPFPHSLMLAFIAEYDGGDIRPQEGEIEDAGWFDIDALP
GLPMPISIAHRLIRHACDRIRDLEA

Sequences:

>Translated_265_residues
MPFELPQQPAPELPERWCVFNGSLLWLQDNQLPAQPPAGCALTGQRFLGIHEGSNLFLADLVGDMPAQAGEWLPLRPALL
AMPMAQVQAAARAAQLRQFFHSHRFCGHCATPLAVSADQLGRHCPSCGQVYYPRISPAMMVLVRRGRELLLARSPHFAPG
MYSALAGFVEPGETLEECVHRETWEEVGVKVKNLRYAFSQSWPFPHSLMLAFIAEYDGGDIRPQEGEIEDAGWFDIDALP
GLPMPISIAHRLIRHACDRIRDLEA
>Mature_264_residues
PFELPQQPAPELPERWCVFNGSLLWLQDNQLPAQPPAGCALTGQRFLGIHEGSNLFLADLVGDMPAQAGEWLPLRPALLA
MPMAQVQAAARAAQLRQFFHSHRFCGHCATPLAVSADQLGRHCPSCGQVYYPRISPAMMVLVRRGRELLLARSPHFAPGM
YSALAGFVEPGETLEECVHRETWEEVGVKVKNLRYAFSQSWPFPHSLMLAFIAEYDGGDIRPQEGEIEDAGWFDIDALPG
LPMPISIAHRLIRHACDRIRDLEA

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Homo sapiens, GI50593112, Length=212, Percent_Identity=34.9056603773585, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI13899267, Length=203, Percent_Identity=36.4532019704434, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI48994995, Length=237, Percent_Identity=41.3502109704641, Blast_Score=177, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI71986510, Length=171, Percent_Identity=35.0877192982456, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI212645999, Length=171, Percent_Identity=35.0877192982456, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6321371, Length=201, Percent_Identity=29.8507462686567, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUDC_CHRVO (Q7NTZ8)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_902575.1
- HSSP:   P32664
- ProteinModelPortal:   Q7NTZ8
- SMR:   Q7NTZ8
- GeneID:   2548619
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_2905
- NMPDR:   fig|243365.1.peg.2905
- HOGENOM:   HBG736436
- OMA:   SPCIIVA
- PhylomeDB:   Q7NTZ8
- BioCyc:   CVIO243365:CV_2905-MONOMER
- HAMAP:   MF_00297
- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376
- Gene3D:   G3DSA:3.90.79.10

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase; SSF55811 NUDIX_hydrolase

EC number: =3.6.1.22

Molecular weight: Translated: 29485; Mature: 29354

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFELPQQPAPELPERWCVFNGSLLWLQDNQLPAQPPAGCALTGQRFLGIHEGSNLFLAD
CCCCCCCCCCCCCCHHHEEECCCEEEEECCCCCCCCCCCCEECCCCEEEEECCCCEEHHH
LVGDMPAQAGEWLPLRPALLAMPMAQVQAAARAAQLRQFFHSHRFCGHCATPLAVSADQL
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECHHHH
GRHCPSCGQVYYPRISPAMMVLVRRGRELLLARSPHFAPGMYSALAGFVEPGETLEECVH
HCCCCCCCCEECCCCCHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHH
RETWEEVGVKVKNLRYAFSQSWPFPHSLMLAFIAEYDGGDIRPQEGEIEDAGWFDIDALP
HHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCC
GLPMPISIAHRLIRHACDRIRDLEA
CCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PFELPQQPAPELPERWCVFNGSLLWLQDNQLPAQPPAGCALTGQRFLGIHEGSNLFLAD
CCCCCCCCCCCCCHHHEEECCCEEEEECCCCCCCCCCCCEECCCCEEEEECCCCEEHHH
LVGDMPAQAGEWLPLRPALLAMPMAQVQAAARAAQLRQFFHSHRFCGHCATPLAVSADQL
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECHHHH
GRHCPSCGQVYYPRISPAMMVLVRRGRELLLARSPHFAPGMYSALAGFVEPGETLEECVH
HCCCCCCCCEECCCCCHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHH
RETWEEVGVKVKNLRYAFSQSWPFPHSLMLAFIAEYDGGDIRPQEGEIEDAGWFDIDALP
HHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCC
GLPMPISIAHRLIRHACDRIRDLEA
CCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782