Click here to switch to the map view.

The map label for this gene is sdaA1 [H]

Identifier: 34498329

GI number: 34498329

Start: 3148670

End: 3150070

Strand: Direct

Name: sdaA1 [H]

Synonym: CV_2874

Alternate gene names: 34498329

Gene position: 3148670-3150070 (Clockwise)

Preceding gene: 34498320

Following gene: 34498330

Centisome position: 66.27

GC content: 66.02

Gene sequence:

>1401_bases
ATGGCAATCAGTGTTTTCGACCTGTTCAAAATCGGCATCGGCCCGTCCAGCTCCCACACCGTGGGCCCGATGCGCGCCGC
CCGCCAATTCATCAGCCGCCTGGAAAAGGACGGCCAGCTGGACGCCACTGTCCGCGTCAGCGCCGAGATGTTCGGTTCGC
TGGGCGCCACCGGCAAGGGCCACGGCACCGATGTGGCGGTGCTGCTGGGCCTGCAGGGCGAGCAACCTGACCTGGTCGAC
ACCGATGCAGTGGACGGCATGCTGGCCGCCATCCGCGAGCAGCGCAAACTGAAGCTGCTGGGCAAGCGCGAGATCGATTT
CGTCGAAAGCGAGCACCTGATCCTGCACAAAAAGAAAACCCTGCCCTACCACCCCAACGGCATGATCTTCGAGGCCTTCG
ACGCCGCCGGCGAAAGCCTGTCCAAGCGCGCCTACTATTCGGTAGGCGGCGGCTTCGTGGTCGACGAAGCGGCGATCGAC
GCCGGCTTCGTCCCGCCGGGCGTCACCGAGCTGAAGCACCCGTTCAAGAGCGCGGCCGAGCTGTTGGCGCTGTGCCAGCG
CCACGGCAAGAGCATCAGCCAGATCATGCTGGAGAACGAGCTGTCCTGGCGCAGCGAGGAAGAAGTGCGCGCCGGCCTGC
TCAACATCTGGAACGTGATGCAGGCCTGCGTGAAGCGCGGCTGCGAACGCGAAGGCATCCTGCCGGGCGGCATGAAGGTG
AAGCGCCGCGCCGCCGACATGCACCGCAAACTGCTGGCTTCTCCGGAAGCCGCGATGCGCGACCCGCTGACGGTGATGGA
CTGGGTGAACCTGTACGCCTTGGCCGTGAATGAAGAAAACGCCGCCGGCGGCCGTGTGGTGACCGCTCCGACCAATGGCG
CCGCCGGCATCATCCCGGCCGTGATGCACTACTACGCCCGCTTCGTGCCGGGCGCCAGCGACGACGGCATCGTCCGCTTC
CTGCTGACCGCCGGCGCCATCGGCATCCTGTTCAAGCTGAACGCGTCCATTTCCGGCGCCGAAGTCGGCTGCCAGGGCGA
AGTGGGTTCGGCTTGCTCGATGGCCGCCGGCGCGCTGTGCGAAGTGATGGGCGGCACGCCGGAACAAGTGGAAAACGCCG
CGGAGATCGGCATGGAGCACAATCTGGGCCTGACCTGCGACCCGGTGGGCGGCCTGGTGCAAGTGCCCTGCATCGAGCGC
AACGCGATGGCTTCGGTGAAGGCGATCAACGCGGTGCGGATGGCGCTGCGCGGCGACGGCCAGCACTTCGTGTCGCTGGA
CCGCGTGATCAAGACCATGCGCGACACCGGCATGGACATGAGCACCAAGTACAAGGAAACCGCGCGCGGCGGCCTGGCGA
TCAATGTGATCGAGGTGCCGGTCAACATCGTCGAGTGCTGA

Upstream 100 bases:

>100_bases
CCCTCGCCCGGCAACCATTACAATACAAACTAAGAGACGCCTCGCGGCGCCCGACAACAACCTGGCCCGAGCCGGGAATT
TCCCTTAGAGAAGCATTACC

Downstream 100 bases:

>100_bases
CCCCAGCTCTAAGCAAAAAAAGCCGCGGCGAAAACCGCGGCTTTTTTTATTGGCTAAGCTCCGGCCCGCTGGCACACTGT
GGCCTGTCCCACCCACACCC

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MAISVFDLFKIGIGPSSSHTVGPMRAARQFISRLEKDGQLDATVRVSAEMFGSLGATGKGHGTDVAVLLGLQGEQPDLVD
TDAVDGMLAAIREQRKLKLLGKREIDFVESEHLILHKKKTLPYHPNGMIFEAFDAAGESLSKRAYYSVGGGFVVDEAAID
AGFVPPGVTELKHPFKSAAELLALCQRHGKSISQIMLENELSWRSEEEVRAGLLNIWNVMQACVKRGCEREGILPGGMKV
KRRAADMHRKLLASPEAAMRDPLTVMDWVNLYALAVNEENAAGGRVVTAPTNGAAGIIPAVMHYYARFVPGASDDGIVRF
LLTAGAIGILFKLNASISGAEVGCQGEVGSACSMAAGALCEVMGGTPEQVENAAEIGMEHNLGLTCDPVGGLVQVPCIER
NAMASVKAINAVRMALRGDGQHFVSLDRVIKTMRDTGMDMSTKYKETARGGLAINVIEVPVNIVEC

Sequences:

>Translated_466_residues
MAISVFDLFKIGIGPSSSHTVGPMRAARQFISRLEKDGQLDATVRVSAEMFGSLGATGKGHGTDVAVLLGLQGEQPDLVD
TDAVDGMLAAIREQRKLKLLGKREIDFVESEHLILHKKKTLPYHPNGMIFEAFDAAGESLSKRAYYSVGGGFVVDEAAID
AGFVPPGVTELKHPFKSAAELLALCQRHGKSISQIMLENELSWRSEEEVRAGLLNIWNVMQACVKRGCEREGILPGGMKV
KRRAADMHRKLLASPEAAMRDPLTVMDWVNLYALAVNEENAAGGRVVTAPTNGAAGIIPAVMHYYARFVPGASDDGIVRF
LLTAGAIGILFKLNASISGAEVGCQGEVGSACSMAAGALCEVMGGTPEQVENAAEIGMEHNLGLTCDPVGGLVQVPCIER
NAMASVKAINAVRMALRGDGQHFVSLDRVIKTMRDTGMDMSTKYKETARGGLAINVIEVPVNIVEC
>Mature_465_residues
AISVFDLFKIGIGPSSSHTVGPMRAARQFISRLEKDGQLDATVRVSAEMFGSLGATGKGHGTDVAVLLGLQGEQPDLVDT
DAVDGMLAAIREQRKLKLLGKREIDFVESEHLILHKKKTLPYHPNGMIFEAFDAAGESLSKRAYYSVGGGFVVDEAAIDA
GFVPPGVTELKHPFKSAAELLALCQRHGKSISQIMLENELSWRSEEEVRAGLLNIWNVMQACVKRGCEREGILPGGMKVK
RRAADMHRKLLASPEAAMRDPLTVMDWVNLYALAVNEENAAGGRVVTAPTNGAAGIIPAVMHYYARFVPGASDDGIVRFL
LTAGAIGILFKLNASISGAEVGCQGEVGSACSMAAGALCEVMGGTPEQVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMASVKAINAVRMALRGDGQHFVSLDRVIKTMRDTGMDMSTKYKETARGGLAINVIEVPVNIVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=455, Percent_Identity=55.3846153846154, Blast_Score=510, Evalue=1e-146,
Organism=Escherichia coli, GI48994925, Length=456, Percent_Identity=54.6052631578947, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI1789161, Length=456, Percent_Identity=52.8508771929825, Blast_Score=479, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49744; Mature: 49613

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISVFDLFKIGIGPSSSHTVGPMRAARQFISRLEKDGQLDATVRVSAEMFGSLGATGKG
CEEEHEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCCC
HGTDVAVLLGLQGEQPDLVDTDAVDGMLAAIREQRKLKLLGKREIDFVESEHLILHKKKT
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCC
LPYHPNGMIFEAFDAAGESLSKRAYYSVGGGFVVDEAAIDAGFVPPGVTELKHPFKSAAE
CCCCCCCCEEEHHHHHHHHHHHHHEEECCCCEEEEHHHCCCCCCCCCHHHHHHHHHHHHH
LLALCQRHGKSISQIMLENELSWRSEEEVRAGLLNIWNVMQACVKRGCEREGILPGGMKV
HHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
KRRAADMHRKLLASPEAAMRDPLTVMDWVNLYALAVNEENAAGGRVVTAPTNGAAGIIPA
HHHHHHHHHHHHCCCHHHHHCCCHHHHHHCEEEEEECCCCCCCCEEEECCCCCCCHHHHH
VMHYYARFVPGASDDGIVRFLLTAGAIGILFKLNASISGAEVGCQGEVGSACSMAAGALC
HHHHHHHHCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
EVMGGTPEQVENAAEIGMEHNLGLTCDPVGGLVQVPCIERNAMASVKAINAVRMALRGDG
HHHCCCHHHHHHHHHCCCCCCCCEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCC
QHFVSLDRVIKTMRDTGMDMSTKYKETARGGLAINVIEVPVNIVEC
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEEECEEEECC
>Mature Secondary Structure 
AISVFDLFKIGIGPSSSHTVGPMRAARQFISRLEKDGQLDATVRVSAEMFGSLGATGKG
EEEHEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCCC
HGTDVAVLLGLQGEQPDLVDTDAVDGMLAAIREQRKLKLLGKREIDFVESEHLILHKKKT
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCC
LPYHPNGMIFEAFDAAGESLSKRAYYSVGGGFVVDEAAIDAGFVPPGVTELKHPFKSAAE
CCCCCCCCEEEHHHHHHHHHHHHHEEECCCCEEEEHHHCCCCCCCCCHHHHHHHHHHHHH
LLALCQRHGKSISQIMLENELSWRSEEEVRAGLLNIWNVMQACVKRGCEREGILPGGMKV
HHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
KRRAADMHRKLLASPEAAMRDPLTVMDWVNLYALAVNEENAAGGRVVTAPTNGAAGIIPA
HHHHHHHHHHHHCCCHHHHHCCCHHHHHHCEEEEEECCCCCCCCEEEECCCCCCCHHHHH
VMHYYARFVPGASDDGIVRFLLTAGAIGILFKLNASISGAEVGCQGEVGSACSMAAGALC
HHHHHHHHCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
EVMGGTPEQVENAAEIGMEHNLGLTCDPVGGLVQVPCIERNAMASVKAINAVRMALRGDG
HHHCCCHHHHHHHHHCCCCCCCCEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCC
QHFVSLDRVIKTMRDTGMDMSTKYKETARGGLAINVIEVPVNIVEC
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]