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The map label for this gene is yafC [H]

Identifier: 34498007

GI number: 34498007

Start: 2744417

End: 2745340

Strand: Direct

Name: yafC [H]

Synonym: CV_2552

Alternate gene names: 34498007

Gene position: 2744417-2745340 (Clockwise)

Preceding gene: 34497994

Following gene: 34498011

Centisome position: 57.76

GC content: 69.91

Gene sequence:

>924_bases
ATGAAACCGCTATGGGGAATCCGGATATTCTGCGCGGTGGTGGAGCAGAAAAGCTTCGTCTCCGCCGCCCGCCAGCTGGG
CACCTCGCCCAGCAGCGCCACCCGAGCGCTGCAAGCGCTGGAAGAGGAGCTGGGCGCGATGCTGCTGGCCCGCTCCAGCA
AGCAGGTGGAGCTGACCATGGCCGGCGAAGCCTATTACCCCGCCGCCCGCCAGATGCTGGACCTGCAGCAGCAGGCAGAG
GATGAATTGAGCCAGCAGGCCGGCGCGCCGCGCGGCTTGCTGCGCTTCTCCGCGCCGGAAACGCTGGGCCGCGAGCTCTT
GCCCGCCGTGCTGGGCAGGCTGGCCGACACCCACCCCGGGCTGCGATTCGAGGTGCTGTACAGCGATTCGACACTGGAGC
CGATACGGGACAAGCTGGACTTCTCGATCCGCGGCGCCTTTCCCGCGTCCAGCGAGCTGATCGGCCATCCGCTATGGCAT
TACCGCCGCCATCTGTACGCCAGCCCGGACTACGTCGCCCGCCACGGCGCGCCGCAGAGCCCCTCGGACCTGCCCCAGCA
CCGGGTGGTGATCCACACCGCCCCCAGGGTGCTGAAAGCGTGGAATTTCGTGTCGGATGAACAAGCCATCAGCCTCAACC
TCAACGCCTGGCACCGCAGCAACTCCGGCAACGGCGTGCTGGACGCCGTCCGCGCCGGCATGGGCATCGCCCGGCTGGGA
GACTGGCTGGCGGAGCCGCTGGCCGCGCGCGGCGAATTGGTGCGGCTGTGCCCAGCCTTCCGCATCGTGTCCAGCCACGG
CGGCGACCCGCAGATGCACGCGGTTTTCGCCAGCCGCGGCATGCCGCGCAAGGCCCGGCTGCTGCTGGACGCGCTGCGCC
TGGAAGCCCAGGCGCGCGGCTTCGGCCGCCATGCGCCGGGCTGA

Upstream 100 bases:

>100_bases
CAACAACATCGTCATCCTCCTCTTCGACGCGAATTGTACGTGCAGGTCTCAAACAATGCTTGCAATGTTATATTGCAAAA
AACGCAATACAGGGGCCGCA

Downstream 100 bases:

>100_bases
AAGCAAAAAGCCCCGCATGCGCGGGGCTGGAGCCGGGACGGAGCCGGATCAGTTGCTGTCGGTCAGCGATTGCTTGCCGG
CGGTGACCGGGTACTTCTCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKPLWGIRIFCAVVEQKSFVSAARQLGTSPSSATRALQALEEELGAMLLARSSKQVELTMAGEAYYPAARQMLDLQQQAE
DELSQQAGAPRGLLRFSAPETLGRELLPAVLGRLADTHPGLRFEVLYSDSTLEPIRDKLDFSIRGAFPASSELIGHPLWH
YRRHLYASPDYVARHGAPQSPSDLPQHRVVIHTAPRVLKAWNFVSDEQAISLNLNAWHRSNSGNGVLDAVRAGMGIARLG
DWLAEPLAARGELVRLCPAFRIVSSHGGDPQMHAVFASRGMPRKARLLLDALRLEAQARGFGRHAPG

Sequences:

>Translated_307_residues
MKPLWGIRIFCAVVEQKSFVSAARQLGTSPSSATRALQALEEELGAMLLARSSKQVELTMAGEAYYPAARQMLDLQQQAE
DELSQQAGAPRGLLRFSAPETLGRELLPAVLGRLADTHPGLRFEVLYSDSTLEPIRDKLDFSIRGAFPASSELIGHPLWH
YRRHLYASPDYVARHGAPQSPSDLPQHRVVIHTAPRVLKAWNFVSDEQAISLNLNAWHRSNSGNGVLDAVRAGMGIARLG
DWLAEPLAARGELVRLCPAFRIVSSHGGDPQMHAVFASRGMPRKARLLLDALRLEAQARGFGRHAPG
>Mature_307_residues
MKPLWGIRIFCAVVEQKSFVSAARQLGTSPSSATRALQALEEELGAMLLARSSKQVELTMAGEAYYPAARQMLDLQQQAE
DELSQQAGAPRGLLRFSAPETLGRELLPAVLGRLADTHPGLRFEVLYSDSTLEPIRDKLDFSIRGAFPASSELIGHPLWH
YRRHLYASPDYVARHGAPQSPSDLPQHRVVIHTAPRVLKAWNFVSDEQAISLNLNAWHRSNSGNGVLDAVRAGMGIARLG
DWLAEPLAARGELVRLCPAFRIVSSHGGDPQMHAVFASRGMPRKARLLLDALRLEAQARGFGRHAPG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=249, Percent_Identity=35.3413654618474, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI145693193, Length=268, Percent_Identity=30.9701492537313, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789440, Length=256, Percent_Identity=28.125, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI87081978, Length=303, Percent_Identity=28.3828382838284, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789639, Length=297, Percent_Identity=28.956228956229, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1787128, Length=236, Percent_Identity=28.3898305084746, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787601, Length=172, Percent_Identity=30.2325581395349, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787589, Length=254, Percent_Identity=23.6220472440945, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788706, Length=187, Percent_Identity=30.4812834224599, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789173, Length=272, Percent_Identity=23.5294117647059, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788481, Length=167, Percent_Identity=28.1437125748503, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33670; Mature: 33670

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLWGIRIFCAVVEQKSFVSAARQLGTSPSSATRALQALEEELGAMLLARSSKQVELTM
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
AGEAYYPAARQMLDLQQQAEDELSQQAGAPRGLLRFSAPETLGRELLPAVLGRLADTHPG
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCC
LRFEVLYSDSTLEPIRDKLDFSIRGAFPASSELIGHPLWHYRRHLYASPDYVARHGAPQS
CEEEEEECCCCHHHHHHHHCEEEECCCCCCHHHHCCHHHHHHHHHCCCCCHHHHCCCCCC
PSDLPQHRVVIHTAPRVLKAWNFVSDEQAISLNLNAWHRSNSGNGVLDAVRAGMGIARLG
CCCCCCCEEEEECCHHHHHHHCCCCCCCEEEEEEEHEECCCCCCHHHHHHHHCCCHHHHH
DWLAEPLAARGELVRLCPAFRIVSSHGGDPQMHAVFASRGMPRKARLLLDALRLEAQARG
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
FGRHAPG
CCCCCCC
>Mature Secondary Structure
MKPLWGIRIFCAVVEQKSFVSAARQLGTSPSSATRALQALEEELGAMLLARSSKQVELTM
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
AGEAYYPAARQMLDLQQQAEDELSQQAGAPRGLLRFSAPETLGRELLPAVLGRLADTHPG
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCC
LRFEVLYSDSTLEPIRDKLDFSIRGAFPASSELIGHPLWHYRRHLYASPDYVARHGAPQS
CEEEEEECCCCHHHHHHHHCEEEECCCCCCHHHHCCHHHHHHHHHCCCCCHHHHCCCCCC
PSDLPQHRVVIHTAPRVLKAWNFVSDEQAISLNLNAWHRSNSGNGVLDAVRAGMGIARLG
CCCCCCCEEEEECCHHHHHHHCCCCCCCEEEEEEEHEECCCCCCHHHHHHHHCCCHHHHH
DWLAEPLAARGELVRLCPAFRIVSSHGGDPQMHAVFASRGMPRKARLLLDALRLEAQARG
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
FGRHAPG
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]