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The map label for this gene is yhfN [H]

Identifier: 34497822

GI number: 34497822

Start: 2551962

End: 2553209

Strand: Reverse

Name: yhfN [H]

Synonym: CV_2367

Alternate gene names: 34497822

Gene position: 2553209-2551962 (Counterclockwise)

Preceding gene: 34497827

Following gene: 34497821

Centisome position: 53.74

GC content: 64.02

Gene sequence:

>1248_bases
ATGACCGAGGCTTTCTCCCTACTGTTCGCCGCCGCGCTGACGCTAACCCTATGCCTGAAGCTTTGGCTGGGCTGGCGCCA
TATCCGACACATCGCCCGCCATCGCGACCAGGTTCCGGCGGCCTTCCGCGACAGCATCACCTTGGAGCAGCACCGGCACG
CCGCCGACTACACCATCGCCAAGACCAAGCTGGGCCTGCTGTCCGCCTGGGTGGACACCGCGCTGATCGCGGCTTTCACT
TTCGGCGGTGGATTGCAATGGCTGGCCGTCCACAGCATGCAATGGCTCGCCAACCCGCTGCTGTCGGGCATGGCGCTGAT
CGTGTCGGTCGCCGTGATCAGCAGCTTGGTTTCGCTGCCCTTCACTCTGTACGGCACCTTCGGCATTGAAAGCCGCTTCG
GCTTCAATAAGACCACCATCGCGCTGTTCATGGCCGACATGATCAAGGGCGCTCTGGTCGGCGCGGCGATCGGCCTGCCC
TTGCTGGCGCTGGTGCTGTGGCTGATGGAGATCTCCGGCCCGCTGTGGTGGCTGTGGGTATGGCTGGTCTGGTCCGGCTT
CCAGTTGCTGATGGTCGCGTTGTACCCGACGCTGATCGCGCCGCTGTTCAACAAGTTCAAACCGCTGGAGGATGAGATGC
TCAAAACCCGCATTGAAGCCTTGCTCCAGCGCGCCGGCTTCAAAAGCCAGGGCGTGTTCGTGATGGACGGCTCGCGCCGC
TCCAGCCACGGCAATGCCTACTTCACCGGCTTCGGCTCCGCCAAGCGCATTGTGTTCTTCGACACGCTGCTATCCCAGCT
CAGCCACGCCGAGATCGAAGCGGTGCTGGCGCACGAGCTGGGCCACTTCAAGCGCCGCCACATCGTCAAGCGCATCGCCT
TGGCCTTCGCCTTGTCTCTGGCCTTGCTGTGGCTGCTGGGCCAATTGCTGCATGCGCCATGGTTCTACGCCGGCCTCGGC
GTCGCCGCGCCCAGCACGGCGATGGCGCTGATCCTGTTCCTTACCGCGACGCCGGCCTTCACTTTCCCGCTGACGCCGCT
GTCCAGCCGGATGTCCCGCGTCCATGAATACGAGGCCGACGATTTCGCGTCGGAACAGACCCGGGCGGACGACCTGGTCA
GCGCCTTGGTCAAGCTGTACCGCGACAACGCGTCCACGCTGACGCCGGACCCCATCCATTCCGCCTTCTACGATTCGCAC
CCGCCAGCGGCGCTGCGCATCCAACACCTGAAAGGAAACCACGCATGA

Upstream 100 bases:

>100_bases
CCAGATGAGGTTATTGGTATCTTGTGCCATACTAGTCAATCTTTAGAAAACCCTGCCATTTTCCTTCATTGCCGCGTCGT
CGGCAAACTCCAGGACACCC

Downstream 100 bases:

>100_bases
ACCTGTTGGAGCTATCCTGCACTCCTCAGCATGGCCAGAGTCCGCTGGCCGACAACACCGTCAAGCAACTGCTCTCCACG
CTGCCGGACTGGGAAATCGT

Product: transmembrane protease

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MTEAFSLLFAAALTLTLCLKLWLGWRHIRHIARHRDQVPAAFRDSITLEQHRHAADYTIAKTKLGLLSAWVDTALIAAFT
FGGGLQWLAVHSMQWLANPLLSGMALIVSVAVISSLVSLPFTLYGTFGIESRFGFNKTTIALFMADMIKGALVGAAIGLP
LLALVLWLMEISGPLWWLWVWLVWSGFQLLMVALYPTLIAPLFNKFKPLEDEMLKTRIEALLQRAGFKSQGVFVMDGSRR
SSHGNAYFTGFGSAKRIVFFDTLLSQLSHAEIEAVLAHELGHFKRRHIVKRIALAFALSLALLWLLGQLLHAPWFYAGLG
VAAPSTAMALILFLTATPAFTFPLTPLSSRMSRVHEYEADDFASEQTRADDLVSALVKLYRDNASTLTPDPIHSAFYDSH
PPAALRIQHLKGNHA

Sequences:

>Translated_415_residues
MTEAFSLLFAAALTLTLCLKLWLGWRHIRHIARHRDQVPAAFRDSITLEQHRHAADYTIAKTKLGLLSAWVDTALIAAFT
FGGGLQWLAVHSMQWLANPLLSGMALIVSVAVISSLVSLPFTLYGTFGIESRFGFNKTTIALFMADMIKGALVGAAIGLP
LLALVLWLMEISGPLWWLWVWLVWSGFQLLMVALYPTLIAPLFNKFKPLEDEMLKTRIEALLQRAGFKSQGVFVMDGSRR
SSHGNAYFTGFGSAKRIVFFDTLLSQLSHAEIEAVLAHELGHFKRRHIVKRIALAFALSLALLWLLGQLLHAPWFYAGLG
VAAPSTAMALILFLTATPAFTFPLTPLSSRMSRVHEYEADDFASEQTRADDLVSALVKLYRDNASTLTPDPIHSAFYDSH
PPAALRIQHLKGNHA
>Mature_414_residues
TEAFSLLFAAALTLTLCLKLWLGWRHIRHIARHRDQVPAAFRDSITLEQHRHAADYTIAKTKLGLLSAWVDTALIAAFTF
GGGLQWLAVHSMQWLANPLLSGMALIVSVAVISSLVSLPFTLYGTFGIESRFGFNKTTIALFMADMIKGALVGAAIGLPL
LALVLWLMEISGPLWWLWVWLVWSGFQLLMVALYPTLIAPLFNKFKPLEDEMLKTRIEALLQRAGFKSQGVFVMDGSRRS
SHGNAYFTGFGSAKRIVFFDTLLSQLSHAEIEAVLAHELGHFKRRHIVKRIALAFALSLALLWLLGQLLHAPWFYAGLGV
AAPSTAMALILFLTATPAFTFPLTPLSSRMSRVHEYEADDFASEQTRADDLVSALVKLYRDNASTLTPDPIHSAFYDSHP
PAALRIQHLKGNHA

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=457, Percent_Identity=32.3851203501094, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17505484, Length=440, Percent_Identity=31.5909090909091, Blast_Score=198, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6322577, Length=428, Percent_Identity=32.4766355140187, Blast_Score=201, Evalue=1e-52,
Organism=Drosophila melanogaster, GI19922414, Length=423, Percent_Identity=32.1513002364066, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24654305, Length=415, Percent_Identity=27.710843373494, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI78707252, Length=398, Percent_Identity=25.3768844221106, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI78707254, Length=398, Percent_Identity=25.3768844221106, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 46033; Mature: 45902

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAFSLLFAAALTLTLCLKLWLGWRHIRHIARHRDQVPAAFRDSITLEQHRHAADYTIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHH
KTKLGLLSAWVDTALIAAFTFGGGLQWLAVHSMQWLANPLLSGMALIVSVAVISSLVSLP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FTLYGTFGIESRFGFNKTTIALFMADMIKGALVGAAIGLPLLALVLWLMEISGPLWWLWV
HHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
WLVWSGFQLLMVALYPTLIAPLFNKFKPLEDEMLKTRIEALLQRAGFKSQGVFVMDGSRR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
SSHGNAYFTGFGSAKRIVFFDTLLSQLSHAEIEAVLAHELGHFKRRHIVKRIALAFALSL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLWLLGQLLHAPWFYAGLGVAAPSTAMALILFLTATPAFTFPLTPLSSRMSRVHEYEAD
HHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCH
DFASEQTRADDLVSALVKLYRDNASTLTPDPIHSAFYDSHPPAALRIQHLKGNHA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHEEEECCCCCCC
>Mature Secondary Structure 
TEAFSLLFAAALTLTLCLKLWLGWRHIRHIARHRDQVPAAFRDSITLEQHRHAADYTIA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHH
KTKLGLLSAWVDTALIAAFTFGGGLQWLAVHSMQWLANPLLSGMALIVSVAVISSLVSLP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FTLYGTFGIESRFGFNKTTIALFMADMIKGALVGAAIGLPLLALVLWLMEISGPLWWLWV
HHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
WLVWSGFQLLMVALYPTLIAPLFNKFKPLEDEMLKTRIEALLQRAGFKSQGVFVMDGSRR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
SSHGNAYFTGFGSAKRIVFFDTLLSQLSHAEIEAVLAHELGHFKRRHIVKRIALAFALSL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLWLLGQLLHAPWFYAGLGVAAPSTAMALILFLTATPAFTFPLTPLSSRMSRVHEYEAD
HHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCH
DFASEQTRADDLVSALVKLYRDNASTLTPDPIHSAFYDSHPPAALRIQHLKGNHA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]