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The map label for this gene is pphA [H]

Identifier: 34497643

GI number: 34497643

Start: 2360198

End: 2360920

Strand: Reverse

Name: pphA [H]

Synonym: CV_2188

Alternate gene names: 34497643

Gene position: 2360920-2360198 (Counterclockwise)

Preceding gene: 34497644

Following gene: 34497642

Centisome position: 49.69

GC content: 69.16

Gene sequence:

>723_bases
ATGATGATCAGGAAACTGCCGCGCAACACGCAAGGCCGGGACTGGGTGGTCGGCGACGTTCACGGCTGCTTCGCCCAACT
GGCCCGGCTGCTCAAGATCATCGCCTTCGATCCCGCCCGCGACCGCCTGCTATCCGTCGGCGACCTGGTGGATAGGGGGC
CGGACAGCGCGATGGTCGGCGAATGGCTGGCCCAGCCGTGGTTTCACGCCGTGCGAGGCAATCACGAGCAAATGGCGCTG
GACGCGATGCGGGATCCCCTGCGCGACCTGGAGCGTCATCTGCGCAACGGCGGCCGCTGGCTGACGGAATTGTCTCCCGC
CGAGCGCGACGCCTGCGTGGCCGCCCTGTCCGGCTTGCCGCTGGCGCTGGAGGTGGACACCGAGGGCGGCAAGATAGGCG
TGCTCCACGCCGACTGCCCCGGCAACGACTGGACCGCGATGGCCGCGAGGCTGGAAGCCGGCCAGCCCGCCGCGCAAGAC
AGCGATGTGCTGCTGTGGGCGCGCGACCGCGTGCAAAACGGCGGCGGCGGCGCCGCGGCCGGCGTGGAGCTGGTGCTGGC
CGGACACACGCCGCAACCCCGCGCCATCCTGTACGACAATGTGATGCACCTGGACACCGGCGCCGTCTACGGCGGCAAGC
TCACCGTGTTCTGCCTTCAGGATTTCGTCGAAGTGTCGCTGCCGTCCGGTTTCGAGCACCTGGCCCGCTTCGAGCTGCAT
TGA

Upstream 100 bases:

>100_bases
CGCCATGGCCGAGCGCAAGCTGGAATGGCTGTTCCATTTCCGCGACGAGTTCTGCCGGGACTGGATGGCCCGCTGAGACA
AAACCGCCGGGAGCGCCGCC

Downstream 100 bases:

>100_bases
GCATGCGTTGGCAGGCTCTAGCCGCGGGCCACGCCCGCCGCTAGAATGCGCGCTCAGCAGACCAAGGACACGACAATGGC
CGAGCGCAACAAGAAAACCG

Product: phosphoprotein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MMIRKLPRNTQGRDWVVGDVHGCFAQLARLLKIIAFDPARDRLLSVGDLVDRGPDSAMVGEWLAQPWFHAVRGNHEQMAL
DAMRDPLRDLERHLRNGGRWLTELSPAERDACVAALSGLPLALEVDTEGGKIGVLHADCPGNDWTAMAARLEAGQPAAQD
SDVLLWARDRVQNGGGGAAAGVELVLAGHTPQPRAILYDNVMHLDTGAVYGGKLTVFCLQDFVEVSLPSGFEHLARFELH

Sequences:

>Translated_240_residues
MMIRKLPRNTQGRDWVVGDVHGCFAQLARLLKIIAFDPARDRLLSVGDLVDRGPDSAMVGEWLAQPWFHAVRGNHEQMAL
DAMRDPLRDLERHLRNGGRWLTELSPAERDACVAALSGLPLALEVDTEGGKIGVLHADCPGNDWTAMAARLEAGQPAAQD
SDVLLWARDRVQNGGGGAAAGVELVLAGHTPQPRAILYDNVMHLDTGAVYGGKLTVFCLQDFVEVSLPSGFEHLARFELH
>Mature_240_residues
MMIRKLPRNTQGRDWVVGDVHGCFAQLARLLKIIAFDPARDRLLSVGDLVDRGPDSAMVGEWLAQPWFHAVRGNHEQMAL
DAMRDPLRDLERHLRNGGRWLTELSPAERDACVAALSGLPLALEVDTEGGKIGVLHADCPGNDWTAMAARLEAGQPAAQD
SDVLLWARDRVQNGGGGAAAGVELVLAGHTPQPRAILYDNVMHLDTGAVYGGKLTVFCLQDFVEVSLPSGFEHLARFELH

Specific function: Can hydrolyze phosphorylated Ser-, Thr- or Tyr- substrates in vitro. The natural substrate is unknown [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPP phosphatase family. PP-1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081988, Length=212, Percent_Identity=39.1509433962264, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789090, Length=212, Percent_Identity=34.9056603773585, Blast_Score=119, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 26154; Mature: 26154

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00125 SER_THR_PHOSPHATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIRKLPRNTQGRDWVVGDVHGCFAQLARLLKIIAFDPARDRLLSVGDLVDRGPDSAMVG
CCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHH
EWLAQPWFHAVRGNHEQMALDAMRDPLRDLERHLRNGGRWLTELSPAERDACVAALSGLP
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCC
LALEVDTEGGKIGVLHADCPGNDWTAMAARLEAGQPAAQDSDVLLWARDRVQNGGGGAAA
EEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEHHHHCCCCCCCCC
GVELVLAGHTPQPRAILYDNVMHLDTGAVYGGKLTVFCLQDFVEVSLPSGFEHLARFELH
CEEEEEECCCCCCCEEEECCEEEECCCCEECCEEEEHHHHHHHHHCCCCCHHHHHHHCCC
>Mature Secondary Structure
MMIRKLPRNTQGRDWVVGDVHGCFAQLARLLKIIAFDPARDRLLSVGDLVDRGPDSAMVG
CCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHH
EWLAQPWFHAVRGNHEQMALDAMRDPLRDLERHLRNGGRWLTELSPAERDACVAALSGLP
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCC
LALEVDTEGGKIGVLHADCPGNDWTAMAARLEAGQPAAQDSDVLLWARDRVQNGGGGAAA
EEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEHHHHCCCCCCCCC
GVELVLAGHTPQPRAILYDNVMHLDTGAVYGGKLTVFCLQDFVEVSLPSGFEHLARFELH
CEEEEEECCCCCCCEEEECCEEEECCCCEECCEEEEHHHHHHHHHCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11717262; 11677609 [H]