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The map label for this gene is pabA [H]

Identifier: 34497630

GI number: 34497630

Start: 2348052

End: 2348621

Strand: Reverse

Name: pabA [H]

Synonym: CV_2175

Alternate gene names: 34497630

Gene position: 2348621-2348052 (Counterclockwise)

Preceding gene: 34497631

Following gene: 34497629

Centisome position: 49.43

GC content: 61.93

Gene sequence:

>570_bases
ATGCTCCTCGTTATAGATAACTACGATTCCTTCACCTACAACCTGGTGCAGTATTTCGGCGAGCTGGGCCAGGACGTGAA
GGTGTTCCGCAACGATGAAATCACGCTGCAGCAGATCGAAGAACTGAAGCCGCAATACCTGGTGGTCTCCCCCGGCCCCT
GCACGCCCAACGAGGCGGGCGTGTCGGTTCCGGCCATCCTGCACTTTGCCGGCAAGCTGCCCATCATGGGCGTATGCCTG
GGCCACCAGGGCATAGGCCAAGCCTTCGGCGGCAAGGTCGTCCACGCCAAGCAGCTGATGCACGGCAAGGTGTCGCCGGT
CAGCCACCTGGACAAAGGCATGTTCCGCGGCCTGCCCAATCCGGTCACCTGCACCCGCTACCATTCGCTGGTGATCGAGC
GCGAAACGCTGCCGGACTGCCTGGAAGTCACCGCCTGGACCGACGACGGCGAAATCATGGGCGTGCGCCACAAGACGCTG
CCGATCGAGGGCGTGCAGTTCCACCCGGAATCCATTCTCACCGAGCACGGCCACCGCATGCTGGACAACTTCCTGAAGGA
ATTCGCCTGA

Upstream 100 bases:

>100_bases
CCGACTTAAATGACCAGCTTGCCGTGACCCTGGCGCTTGGAACCCATCGCCAGCGCGATAGACCAAATAGATTCCGCAAG
ATATTTGATTTAGGTGAAAA

Downstream 100 bases:

>100_bases
TGCGACTGAGGCCGCTGCTGATCGGCGTCCTGCTGGCCGCTCCCGCCTGGTCCGGCGCGCTGGAAGACTGCACGCGAAGC
CAGGCCGACACCCCCGCCAT

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MLLVIDNYDSFTYNLVQYFGELGQDVKVFRNDEITLQQIEELKPQYLVVSPGPCTPNEAGVSVPAILHFAGKLPIMGVCL
GHQGIGQAFGGKVVHAKQLMHGKVSPVSHLDKGMFRGLPNPVTCTRYHSLVIERETLPDCLEVTAWTDDGEIMGVRHKTL
PIEGVQFHPESILTEHGHRMLDNFLKEFA

Sequences:

>Translated_189_residues
MLLVIDNYDSFTYNLVQYFGELGQDVKVFRNDEITLQQIEELKPQYLVVSPGPCTPNEAGVSVPAILHFAGKLPIMGVCL
GHQGIGQAFGGKVVHAKQLMHGKVSPVSHLDKGMFRGLPNPVTCTRYHSLVIERETLPDCLEVTAWTDDGEIMGVRHKTL
PIEGVQFHPESILTEHGHRMLDNFLKEFA
>Mature_189_residues
MLLVIDNYDSFTYNLVQYFGELGQDVKVFRNDEITLQQIEELKPQYLVVSPGPCTPNEAGVSVPAILHFAGKLPIMGVCL
GHQGIGQAFGGKVVHAKQLMHGKVSPVSHLDKGMFRGLPNPVTCTRYHSLVIERETLPDCLEVTAWTDDGEIMGVRHKTL
PIEGVQFHPESILTEHGHRMLDNFLKEFA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=64.8648648648649, Blast_Score=268, Evalue=1e-73,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=42.2459893048128, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI1788854, Length=193, Percent_Identity=24.3523316062176, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786215, Length=157, Percent_Identity=27.3885350318471, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=50.2702702702703, Blast_Score=203, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=33.8095238095238, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21049; Mature: 21049

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVIDNYDSFTYNLVQYFGELGQDVKVFRNDEITLQQIEELKPQYLVVSPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCEEEEECCCCCCCCCC
VSVPAILHFAGKLPIMGVCLGHQGIGQAFGGKVVHAKQLMHGKVSPVSHLDKGMFRGLPN
CCHHHHHHHHCCCCEEEEEECCCCCCHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCC
PVTCTRYHSLVIERETLPDCLEVTAWTDDGEIMGVRHKTLPIEGVQFHPESILTEHGHRM
CEEHHHHHHEEEECCCCCCHHEEEEECCCCCEEEEEECCCCCCCCEECHHHHHHHHHHHH
LDNFLKEFA
HHHHHHHCC
>Mature Secondary Structure
MLLVIDNYDSFTYNLVQYFGELGQDVKVFRNDEITLQQIEELKPQYLVVSPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCEEEEECCCCCCCCCC
VSVPAILHFAGKLPIMGVCLGHQGIGQAFGGKVVHAKQLMHGKVSPVSHLDKGMFRGLPN
CCHHHHHHHHCCCCEEEEEECCCCCCHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCC
PVTCTRYHSLVIERETLPDCLEVTAWTDDGEIMGVRHKTLPIEGVQFHPESILTEHGHRM
CEEHHHHHHEEEECCCCCCHHEEEEECCCCCEEEEEECCCCCCCCEECHHHHHHHHHHHH
LDNFLKEFA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2404959; 659439 [H]