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The map label for this gene is dam [H]

Identifier: 34497566

GI number: 34497566

Start: 2300705

End: 2301481

Strand: Reverse

Name: dam [H]

Synonym: CV_2111

Alternate gene names: 34497566

Gene position: 2301481-2300705 (Counterclockwise)

Preceding gene: 34497567

Following gene: 34497556

Centisome position: 48.44

GC content: 55.47

Gene sequence:

>777_bases
ATGTTACAAATCCCAGCATCTCCCATCGTGCCCTGGATTGGCGGCAAGCGCCGCTTGGCAAAACATATCCTGCCGCTGTT
TCCTGAACACACGTGCTACGTGGAACCATTCTGTGGTGCCGCGGCGTTGTACTTCCTGAAGGAGCCTGCAAAAGCCGAAG
TGCTGAACGACGTGAACGGGGAGCTCGTCAATCTGTACAGGGTTGTACGCCATCACTTAGAAGAGTTTGTGCGGCAGTTC
AAATGGGCGCTCTCGTCACGGCAAATTTTCAAGTGGCTCCAGATCACACCGGAAGAGACGCTGACGGATATCCAAAGAGC
TGCCAGGTTCTTTTACCTTCAACGGTTAGCGTTTGGAGGCAAGGTCGAGGGACAGACGCTCGGCACGTCGACCACCAGCC
CGCCCCGGTTAAACCTGCTGCGCATGGAGGAAGACTTGTCGGCTGCGCATTTGAGGTTGTCCCGGACATATATCGAAAAC
CTGGACTGGGCAGACTGCATCAAGAAGTACGACCGTGAGCACACGCTGGTCTACTGCGATCCTCCGTATTGGGGTACCGA
AGGATATGGTGTTGAGTTCGGACTGCATCAGTACCAGCGAATGGCTGAGTTGGCCAGGAGCATGAAGGGGAACATGATCA
TTTCGGTCAACGACATCCCGGAAATGCGACAGGCGTTCGATGGGCTGGCCATCGATAGGGTGGACATAAACTACAGCGTT
GGAGGTGGCGGCCGCAGCAAGGAGAGGAAGGGCGAGCTGATCATCCGCAACTGGTGA

Upstream 100 bases:

>100_bases
CCGCAGACGAGACCTGCAAGCCAACCCGAGGCTGCCTACCGTAGGCCTACGGTACTTACAAGCCTATCGGGATATTCCGC
AATAGAAAAGAGCCTTGCAG

Downstream 100 bases:

>100_bases
CAAGCTTCGTGAAACAGCAAAGGGGCCAAGAGGCCCCTTAAAATGCAATTCTGTTGCAGATGCTGCAAAATTGACCAATC
CAATTTATCGCGCAAAATGG

Product: methyltransferase

Products: NA

Alternate protein names: DNA adenine methyltransferase; Deoxyadenosyl-methyltransferase; M.HindIV [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLQIPASPIVPWIGGKRRLAKHILPLFPEHTCYVEPFCGAAALYFLKEPAKAEVLNDVNGELVNLYRVVRHHLEEFVRQF
KWALSSRQIFKWLQITPEETLTDIQRAARFFYLQRLAFGGKVEGQTLGTSTTSPPRLNLLRMEEDLSAAHLRLSRTYIEN
LDWADCIKKYDREHTLVYCDPPYWGTEGYGVEFGLHQYQRMAELARSMKGNMIISVNDIPEMRQAFDGLAIDRVDINYSV
GGGGRSKERKGELIIRNW

Sequences:

>Translated_258_residues
MLQIPASPIVPWIGGKRRLAKHILPLFPEHTCYVEPFCGAAALYFLKEPAKAEVLNDVNGELVNLYRVVRHHLEEFVRQF
KWALSSRQIFKWLQITPEETLTDIQRAARFFYLQRLAFGGKVEGQTLGTSTTSPPRLNLLRMEEDLSAAHLRLSRTYIEN
LDWADCIKKYDREHTLVYCDPPYWGTEGYGVEFGLHQYQRMAELARSMKGNMIISVNDIPEMRQAFDGLAIDRVDINYSV
GGGGRSKERKGELIIRNW
>Mature_258_residues
MLQIPASPIVPWIGGKRRLAKHILPLFPEHTCYVEPFCGAAALYFLKEPAKAEVLNDVNGELVNLYRVVRHHLEEFVRQF
KWALSSRQIFKWLQITPEETLTDIQRAARFFYLQRLAFGGKVEGQTLGTSTTSPPRLNLLRMEEDLSAAHLRLSRTYIEN
LDWADCIKKYDREHTLVYCDPPYWGTEGYGVEFGLHQYQRMAELARSMKGNMIISVNDIPEMRQAFDGLAIDRVDINYSV
GGGGRSKERKGELIIRNW

Specific function: Methylates DNA within the sequence GATC. Directly involved in methyl-directed DNA mismatch repair [H]

COG id: COG0338

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789789, Length=261, Percent_Identity=24.5210727969349, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023095
- InterPro:   IPR002052
- InterPro:   IPR012327 [H]

Pfam domain/function: PF02086 MethyltransfD12 [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 29747; Mature: 29747

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQIPASPIVPWIGGKRRLAKHILPLFPEHTCYVEPFCGAAALYFLKEPAKAEVLNDVNG
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHCCHHHHHHHHCCH
ELVNLYRVVRHHLEEFVRQFKWALSSRQIFKWLQITPEETLTDIQRAARFFYLQRLAFGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
KVEGQTLGTSTTSPPRLNLLRMEEDLSAAHLRLSRTYIENLDWADCIKKYDREHTLVYCD
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEC
PPYWGTEGYGVEFGLHQYQRMAELARSMKGNMIISVNDIPEMRQAFDGLAIDRVDINYSV
CCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCEEEEEEEEEEE
GGGGRSKERKGELIIRNW
CCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MLQIPASPIVPWIGGKRRLAKHILPLFPEHTCYVEPFCGAAALYFLKEPAKAEVLNDVNG
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHCCHHHHHHHHCCH
ELVNLYRVVRHHLEEFVRQFKWALSSRQIFKWLQITPEETLTDIQRAARFFYLQRLAFGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
KVEGQTLGTSTTSPPRLNLLRMEEDLSAAHLRLSRTYIENLDWADCIKKYDREHTLVYCD
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEC
PPYWGTEGYGVEFGLHQYQRMAELARSMKGNMIISVNDIPEMRQAFDGLAIDRVDINYSV
CCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCEEEEEEEEEEE
GGGGRSKERKGELIIRNW
CCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]