Click here to switch to the map view.

The map label for this gene is mas [H]

Identifier: 34497498

GI number: 34497498

Start: 2228539

End: 2229537

Strand: Direct

Name: mas [H]

Synonym: CV_2043

Alternate gene names: 34497498

Gene position: 2228539-2229537 (Clockwise)

Preceding gene: 34497493

Following gene: 34497500

Centisome position: 46.91

GC content: 70.37

Gene sequence:

>999_bases
ATGGAAAAAATGTCGGCCATCGTGCAGCAGGCGCCGGGCGGCGTGGAAACGATGGAAATGGGGGAGTGGGACAAGCCGCG
CGCGGCGCCGGGCAAATTGCTGGTGCGGGTGATGGCGGCCGGCGTCAACCGCGCCGACCTGATGCAGCGCGAGGGCCGCT
ATCCGCCGCCGCCGGGCGCCAGCCCGTTGATGGGCCTGGAGGTGGCCGGCGTGGTGGAGGAGGCGGTCGGCGATTCCGCC
TTCCAGCCGGGCGACGCGGTGTTCGGCCTGGTGGAGGGCGGCGGTTATGCCGAATACGCGCTGCTGGACCAGTCGCTGGC
GATCGCCAAGCCCGACCAGCTGTCCTGGGTGGAGGCCGCCGGCTTGCCGGAGGCCTGGATGACGGCCTGGTTCAACCTGG
TGGTGAAGGCCGGGCTGCAGGCCGGCGAACGGGCCTTGATCCATGCCGGCGCCAGCGGCGTCGGCGTCGCGGCGATCCAG
CTGGCGAGGCTGCTCGGCGCGGAAGCCTTCGCCAGCGCCGGCAGCGCCGAGAAACTGGCCTTCTGCCGCGAACTGGGGGC
GAGCCAGGTGTTCAACTACCATGAGACGCCGGCTTTCGGCGAGCGGGTCAAGGCCTGGGGCGGCGCCGACGTGGTGCTGG
ACCCGGTGGGCGCCAGCCACCTGGCGGAAAACCTGCAGGCGTTGAACCCGGATGGACGCCTGGTCAATATCGGCCTGATG
GGCGGCCTGAAGGCCGAACTGGATTTCGGCCGCCTGCTGATGAAGCGCATCAGCCTGATCGGCTCCACGCTGCGTCCGCA
GCCGTTGGCGGTCAAGGCCGAGCTGGCCGCCGCGCTGCGCGATCTGATCCTGCCGGCCTTGCTGGAGGGCCGGGCGCGCG
CCGTGGTGGACAGCAGCTATCCCTGGACCCAGGTGCGGGACGCGCACGCTTACGTCGCGGACAACCGCAATCTGGGCAAG
GTGGTGCTGACGCTGTTTCCGGTGATGGCGGGCGGTTGA

Upstream 100 bases:

>100_bases
GCGCATGGCAATGTTTTTCGATGCGGATTATTTCAACGCGGCGCTTGCGCTCGGGGCGCATGTCCGCATTTGTCGGATAT
CAATCAAGGGGGAAGTCCGA

Downstream 100 bases:

>100_bases
ACGTTTCTTCGCCGCGGCGAGGAATGAAAAACGGAAGCCCGTAGGCTTCCGTTTGCTTTGCGCTGCGGCAGGCGGCGTCG
ATCAGCCCACCCAGCGGCGG

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MEKMSAIVQQAPGGVETMEMGEWDKPRAAPGKLLVRVMAAGVNRADLMQREGRYPPPPGASPLMGLEVAGVVEEAVGDSA
FQPGDAVFGLVEGGGYAEYALLDQSLAIAKPDQLSWVEAAGLPEAWMTAWFNLVVKAGLQAGERALIHAGASGVGVAAIQ
LARLLGAEAFASAGSAEKLAFCRELGASQVFNYHETPAFGERVKAWGGADVVLDPVGASHLAENLQALNPDGRLVNIGLM
GGLKAELDFGRLLMKRISLIGSTLRPQPLAVKAELAAALRDLILPALLEGRARAVVDSSYPWTQVRDAHAYVADNRNLGK
VVLTLFPVMAGG

Sequences:

>Translated_332_residues
MEKMSAIVQQAPGGVETMEMGEWDKPRAAPGKLLVRVMAAGVNRADLMQREGRYPPPPGASPLMGLEVAGVVEEAVGDSA
FQPGDAVFGLVEGGGYAEYALLDQSLAIAKPDQLSWVEAAGLPEAWMTAWFNLVVKAGLQAGERALIHAGASGVGVAAIQ
LARLLGAEAFASAGSAEKLAFCRELGASQVFNYHETPAFGERVKAWGGADVVLDPVGASHLAENLQALNPDGRLVNIGLM
GGLKAELDFGRLLMKRISLIGSTLRPQPLAVKAELAAALRDLILPALLEGRARAVVDSSYPWTQVRDAHAYVADNRNLGK
VVLTLFPVMAGG
>Mature_332_residues
MEKMSAIVQQAPGGVETMEMGEWDKPRAAPGKLLVRVMAAGVNRADLMQREGRYPPPPGASPLMGLEVAGVVEEAVGDSA
FQPGDAVFGLVEGGGYAEYALLDQSLAIAKPDQLSWVEAAGLPEAWMTAWFNLVVKAGLQAGERALIHAGASGVGVAAIQ
LARLLGAEAFASAGSAEKLAFCRELGASQVFNYHETPAFGERVKAWGGADVVLDPVGASHLAENLQALNPDGRLVNIGLM
GGLKAELDFGRLLMKRISLIGSTLRPQPLAVKAELAAALRDLILPALLEGRARAVVDSSYPWTQVRDAHAYVADNRNLGK
VVLTLFPVMAGG

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=42.1686746987952, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=42.1686746987952, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI194239674, Length=301, Percent_Identity=32.5581395348837, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI13236495, Length=301, Percent_Identity=32.5581395348837, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=31.5112540192926, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI194239676, Length=298, Percent_Identity=30.5369127516779, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI24308257, Length=358, Percent_Identity=27.0949720670391, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI41872631, Length=317, Percent_Identity=30.2839116719243, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI28557745, Length=256, Percent_Identity=31.25, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI197927207, Length=199, Percent_Identity=29.1457286432161, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI47519420, Length=345, Percent_Identity=25.2173913043478, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1790485, Length=322, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17507255, Length=319, Percent_Identity=29.4670846394984, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI212642053, Length=310, Percent_Identity=26.1290322580645, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71987554, Length=261, Percent_Identity=28.3524904214559, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=334, Percent_Identity=26.3473053892216, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24581345, Length=319, Percent_Identity=25.705329153605, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920632, Length=311, Percent_Identity=25.7234726688103, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI221330659, Length=311, Percent_Identity=25.7234726688103, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 34854; Mature: 34854

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKMSAIVQQAPGGVETMEMGEWDKPRAAPGKLLVRVMAAGVNRADLMQREGRYPPPPGA
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCC
SPLMGLEVAGVVEEAVGDSAFQPGDAVFGLVEGGGYAEYALLDQSLAIAKPDQLSWVEAA
CCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEHHHHHHCCCCCCCCCCCCHHHHC
GLPEAWMTAWFNLVVKAGLQAGERALIHAGASGVGVAAIQLARLLGAEAFASAGSAEKLA
CCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
FCRELGASQVFNYHETPAFGERVKAWGGADVVLDPVGASHLAENLQALNPDGRLVNIGLM
HHHHHCHHHHCCCCCCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCCCCCEEEEEEC
GGLKAELDFGRLLMKRISLIGSTLRPQPLAVKAELAAALRDLILPALLEGRARAVVDSSY
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEECCCC
PWTQVRDAHAYVADNRNLGKVVLTLFPVMAGG
CCHHHHCCCEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKMSAIVQQAPGGVETMEMGEWDKPRAAPGKLLVRVMAAGVNRADLMQREGRYPPPPGA
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCC
SPLMGLEVAGVVEEAVGDSAFQPGDAVFGLVEGGGYAEYALLDQSLAIAKPDQLSWVEAA
CCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEHHHHHHCCCCCCCCCCCCHHHHC
GLPEAWMTAWFNLVVKAGLQAGERALIHAGASGVGVAAIQLARLLGAEAFASAGSAEKLA
CCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
FCRELGASQVFNYHETPAFGERVKAWGGADVVLDPVGASHLAENLQALNPDGRLVNIGLM
HHHHHCHHHHCCCCCCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCCCCCEEEEEEC
GGLKAELDFGRLLMKRISLIGSTLRPQPLAVKAELAAALRDLILPALLEGRARAVVDSSY
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEECCCC
PWTQVRDAHAYVADNRNLGKVVLTLFPVMAGG
CCHHHHCCCEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]