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The map label for this gene is yeiM [C]

Identifier: 34497495

GI number: 34497495

Start: 2224314

End: 2225615

Strand: Reverse

Name: yeiM [C]

Synonym: CV_2040

Alternate gene names: 34497495

Gene position: 2225615-2224314 (Counterclockwise)

Preceding gene: 34497496

Following gene: 34497494

Centisome position: 46.84

GC content: 66.74

Gene sequence:

>1302_bases
GTGAATACCATCCAAGCACTGGCCGGCATGCTGCTTCTCGTCGCCGCCGCCTATCTGTTTTCGACCAACCGCCGCGCCGT
CAACTGGCGCACCGTGCTGATCGGCCTCGCCATCCAGAACGGCCTGTTCCTGCTGATCAACTACGTGCCCGCCGTCCACC
ACGGCGTCTCCGCCTTCGGCGCCGGCTTCGCCAAGGTGCTGAGCTTCGCCGGCGACGGCGCGGGCTTCATTTTCGGCGAT
CTGGCCAAACCCAGCGGCAAGCTGGGCTTCCTGTTCGCCTTCACCGTGCTGCCGGTGATCATCTTCTTCTCCGCCTTCAG
CGCCCTGCTCTACCATTTCGGCATCCTGCAGCGCGTGGTCGCCGGCCTAGCCTGGGCGATGAAGCGCAGCATGGGCATCT
CCGGCCCGGAAAGCGTAGTGGCCGCCGCCAACATCTTCCTCGGCCAGACCGAAGCGCCGCTGCTGGTCCGCCCCTACATC
CGCCACATGACCCGCTCCGAACTGGCCTGCATCATGATCGCCGGCATGTCCACGCTGTCGGGCGGCGTGCTGGCGGCCTA
CGTCGCCTTTCTCGGCGGATCGGACACGGCAGAGCAGGCGCGCTTCGCCACCTACTTGCTGACTGCCTCCTGCATGAACG
CGGCCGGCGCGGTGGTGTTCTGCAAGATCATGTTCCCGGAAACCTCGCCCGAGGCGCTGTCCAGCAGCAAGCTGCAGTCG
TCCAGGGAAAAGAGCGAGGGCAATTTCGTCAGCGCGGTGGTGACCGGCGCGCTGGACGGCATGAAGATGGCCGCCGCCGT
CGCCACCATCCTGCTGGCCATCGTGGCGTTGATCGCGCTGGCCAACTTCCTGGTGAAGGACGGCCTGGGCGAGCTGCTGG
GCGTCAACGCCGCCATCCAGGCGTCCACCCACAGCATGTTCGACGGCCTGACGCTGCAATACCTGGTGGGCCAGGTGTTC
CGCGTGTTCGCCTTCCTGATGGGCATCGGCTGGAGCGAGACGCTGGGCGTCGGCAGCCTGCTGGGGCAGAAGATCGTCCT
CAACGAGTTCATCGCCTACATGGACCTGGCCAAGATGAAGGCCGCCGGCACGCTGTCCGCGCCGACGGTGATGATCTCCA
CCTTCGCGCTGGCCAGCTTCTCCAATCTGTCGTCGGTGGGCATCTGCGTGGCCGGCATCGGCGCGCTGGCGCCGGAGCGC
CAGCAGGAACTGGCCGCCATCGGCATGCGCGCGCTGGCGGCGTCCATCCTCGCCGGCTTCATGACCGCGACCGCCAGCGG
CCTGTGGCTGTCGCTGTTCTGA

Upstream 100 bases:

>100_bases
CGCGCCTTCAAGCATTAGCCAATCATGATTTGGCGCGGCGCAAGGCATCCGGGACTCGACGGGCGCCGACACGCCGCCCA
TCGCTAGTCCAAGGGCCTCC

Downstream 100 bases:

>100_bases
GCGGATCCGCGACTGACAGCAAGGCGGGAATCCGTTAGCATGCGGTTCCCGCCTTTTTCATAACCGGCCATCGTGAAAGC
AGACTTCTCCTTCTTCGCCA

Product: sodium-dependent nucleoside transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MNTIQALAGMLLLVAAAYLFSTNRRAVNWRTVLIGLAIQNGLFLLINYVPAVHHGVSAFGAGFAKVLSFAGDGAGFIFGD
LAKPSGKLGFLFAFTVLPVIIFFSAFSALLYHFGILQRVVAGLAWAMKRSMGISGPESVVAAANIFLGQTEAPLLVRPYI
RHMTRSELACIMIAGMSTLSGGVLAAYVAFLGGSDTAEQARFATYLLTASCMNAAGAVVFCKIMFPETSPEALSSSKLQS
SREKSEGNFVSAVVTGALDGMKMAAAVATILLAIVALIALANFLVKDGLGELLGVNAAIQASTHSMFDGLTLQYLVGQVF
RVFAFLMGIGWSETLGVGSLLGQKIVLNEFIAYMDLAKMKAAGTLSAPTVMISTFALASFSNLSSVGICVAGIGALAPER
QQELAAIGMRALAASILAGFMTATASGLWLSLF

Sequences:

>Translated_433_residues
MNTIQALAGMLLLVAAAYLFSTNRRAVNWRTVLIGLAIQNGLFLLINYVPAVHHGVSAFGAGFAKVLSFAGDGAGFIFGD
LAKPSGKLGFLFAFTVLPVIIFFSAFSALLYHFGILQRVVAGLAWAMKRSMGISGPESVVAAANIFLGQTEAPLLVRPYI
RHMTRSELACIMIAGMSTLSGGVLAAYVAFLGGSDTAEQARFATYLLTASCMNAAGAVVFCKIMFPETSPEALSSSKLQS
SREKSEGNFVSAVVTGALDGMKMAAAVATILLAIVALIALANFLVKDGLGELLGVNAAIQASTHSMFDGLTLQYLVGQVF
RVFAFLMGIGWSETLGVGSLLGQKIVLNEFIAYMDLAKMKAAGTLSAPTVMISTFALASFSNLSSVGICVAGIGALAPER
QQELAAIGMRALAASILAGFMTATASGLWLSLF
>Mature_433_residues
MNTIQALAGMLLLVAAAYLFSTNRRAVNWRTVLIGLAIQNGLFLLINYVPAVHHGVSAFGAGFAKVLSFAGDGAGFIFGD
LAKPSGKLGFLFAFTVLPVIIFFSAFSALLYHFGILQRVVAGLAWAMKRSMGISGPESVVAAANIFLGQTEAPLLVRPYI
RHMTRSELACIMIAGMSTLSGGVLAAYVAFLGGSDTAEQARFATYLLTASCMNAAGAVVFCKIMFPETSPEALSSSKLQS
SREKSEGNFVSAVVTGALDGMKMAAAVATILLAIVALIALANFLVKDGLGELLGVNAAIQASTHSMFDGLTLQYLVGQVF
RVFAFLMGIGWSETLGVGSLLGQKIVLNEFIAYMDLAKMKAAGTLSAPTVMISTFALASFSNLSSVGICVAGIGALAPER
QQELAAIGMRALAASILAGFMTATASGLWLSLF

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI11545853, Length=438, Percent_Identity=33.7899543378995, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI42542381, Length=437, Percent_Identity=33.6384439359268, Blast_Score=222, Evalue=7e-58,
Organism=Homo sapiens, GI227116277, Length=436, Percent_Identity=32.3394495412844, Blast_Score=216, Evalue=3e-56,
Organism=Escherichia coli, GI1788488, Length=438, Percent_Identity=34.703196347032, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1788485, Length=438, Percent_Identity=34.2465753424658, Blast_Score=241, Evalue=5e-65,
Organism=Escherichia coli, GI1788737, Length=421, Percent_Identity=27.790973871734, Blast_Score=125, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17560276, Length=415, Percent_Identity=33.4939759036145, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71991794, Length=418, Percent_Identity=34.688995215311, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI25146537, Length=199, Percent_Identity=39.1959798994975, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45552519, Length=426, Percent_Identity=33.8028169014084, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI45552517, Length=426, Percent_Identity=33.8028169014084, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI19921868, Length=426, Percent_Identity=33.8028169014084, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI281360430, Length=427, Percent_Identity=32.3185011709602, Blast_Score=191, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 45180; Mature: 45180

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIQALAGMLLLVAAAYLFSTNRRAVNWRTVLIGLAIQNGLFLLINYVPAVHHGVSAFG
CCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AGFAKVLSFAGDGAGFIFGDLAKPSGKLGFLFAFTVLPVIIFFSAFSALLYHFGILQRVV
HHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLAWAMKRSMGISGPESVVAAANIFLGQTEAPLLVRPYIRHMTRSELACIMIAGMSTLS
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEECHHHHC
GGVLAAYVAFLGGSDTAEQARFATYLLTASCMNAAGAVVFCKIMFPETSPEALSSSKLQS
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHH
SREKSEGNFVSAVVTGALDGMKMAAAVATILLAIVALIALANFLVKDGLGELLGVNAAIQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHH
ASTHSMFDGLTLQYLVGQVFRVFAFLMGIGWSETLGVGSLLGQKIVLNEFIAYMDLAKMK
HHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGTLSAPTVMISTFALASFSNLSSVGICVAGIGALAPERQQELAAIGMRALAASILAGF
HCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MTATASGLWLSLF
HHHHCCCCEEEEC
>Mature Secondary Structure
MNTIQALAGMLLLVAAAYLFSTNRRAVNWRTVLIGLAIQNGLFLLINYVPAVHHGVSAFG
CCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AGFAKVLSFAGDGAGFIFGDLAKPSGKLGFLFAFTVLPVIIFFSAFSALLYHFGILQRVV
HHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLAWAMKRSMGISGPESVVAAANIFLGQTEAPLLVRPYIRHMTRSELACIMIAGMSTLS
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEECHHHHC
GGVLAAYVAFLGGSDTAEQARFATYLLTASCMNAAGAVVFCKIMFPETSPEALSSSKLQS
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHH
SREKSEGNFVSAVVTGALDGMKMAAAVATILLAIVALIALANFLVKDGLGELLGVNAAIQ
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHH
ASTHSMFDGLTLQYLVGQVFRVFAFLMGIGWSETLGVGSLLGQKIVLNEFIAYMDLAKMK
HHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGTLSAPTVMISTFALASFSNLSSVGICVAGIGALAPERQQELAAIGMRALAASILAGF
HCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MTATASGLWLSLF
HHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]