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The map label for this gene is eamA [H]

Identifier: 34497359

GI number: 34497359

Start: 2068972

End: 2069874

Strand: Direct

Name: eamA [H]

Synonym: CV_1904

Alternate gene names: 34497359

Gene position: 2068972-2069874 (Clockwise)

Preceding gene: 34497358

Following gene: 34497360

Centisome position: 43.55

GC content: 70.65

Gene sequence:

>903_bases
ATGCCGCTGGCTGACGTGGCGCAGGCGCTGGCCATCGTGCTGGTCTGGGGCGTGAACTTCGTGGTGATCAAATGGGGCGT
GGCCGGCGTGCCGCCGCTGCTGCTGGGCGCGCTGCGTTTCGCGCTGGTGGCGCTGCCGGCGGTATTCGTCATCAGGCGGC
CGGCCCTGCCGTGGCGCTACCTGGCGCTGTATGGGCTGACGGTGGGCGTGGGGCAGTTCGGCTGCCTGTTTTCCGCGATC
AAGCTGGGCATGCCGGCCGGACTCGCCTCGGTGGTGCTGCAGTCGCAGGCCTTTTTCACGCTGCTGCTGGCTCGGGTGTT
TCTAGGCGAGCGCTGGCAGGCCAGCCAGCTGGTTGGCCTGCTGCTGGCTTTGGGCGGCCTGGCGCTGATCGGCATGGGCA
AGGGCGGCGACATGACCGCGGTCGGCTTCGGCCTGACCATCGCCGCGGCCACCAGCTGGGCAGCGTCCAATGTCGTGGTG
CGCGCGATAGGCCGCGCCGGCTTCAAGGTGGAGCCGCTGGGCCTGGTGGTGTGGTCCAGCCTGGTGCCGCCGATTCCCTT
CCTGCTGTTGTCGTGGCGGCTGGAAGGCGGCGAGCGCATGGCGGCGGCGCTGCGAGGCTTCGACGGGCAGTCGCTGTTCG
CCGTCGCCTATCTGGCCTTTGTGGCCACCATGTTCGGCTATGGGCTGTGGAGCCGCCTGCTGGCGCGGCACGCCGCGGCC
AAGGTGGCGCCGTTCTCGCTGCTGGTGCCGGTGGTGGGATTGCTGGCTTCGCACTGGCTGCTGAGCGAGACGCTGACGCC
CGCTCAGTTGGCCGGCAGCGGCCTGCTGATGGCCGGCCTGCTGGCCACGGTGTTCGGCGGCAGGCTGTTGGCGGCGGCGG
AGGGCAGGACTCGCCGTGCGTGA

Upstream 100 bases:

>100_bases
GCGCTGGCGCAGGGCTATCGGCTGCATGGCTCGCCGGCGGCCACCTTCAACGGCGAGCGCGTGATCGTCGCGCAGGCGGT
GCTGTGGCCGGGAGCGAACG

Downstream 100 bases:

>100_bases
CGTCTATTTCCTGCTGTCGCCCTGCGTGCTGCTGCTGGACCTGGCCGGCCCGGCCGACGCTTTCAGGCTGGCAGGCCAGC
ATGGCGCGGCGTTCCGGCTG

Product: DMT superfamily transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MPLADVAQALAIVLVWGVNFVVIKWGVAGVPPLLLGALRFALVALPAVFVIRRPALPWRYLALYGLTVGVGQFGCLFSAI
KLGMPAGLASVVLQSQAFFTLLLARVFLGERWQASQLVGLLLALGGLALIGMGKGGDMTAVGFGLTIAAATSWAASNVVV
RAIGRAGFKVEPLGLVVWSSLVPPIPFLLLSWRLEGGERMAAALRGFDGQSLFAVAYLAFVATMFGYGLWSRLLARHAAA
KVAPFSLLVPVVGLLASHWLLSETLTPAQLAGSGLLMAGLLATVFGGRLLAAAEGRTRRA

Sequences:

>Translated_300_residues
MPLADVAQALAIVLVWGVNFVVIKWGVAGVPPLLLGALRFALVALPAVFVIRRPALPWRYLALYGLTVGVGQFGCLFSAI
KLGMPAGLASVVLQSQAFFTLLLARVFLGERWQASQLVGLLLALGGLALIGMGKGGDMTAVGFGLTIAAATSWAASNVVV
RAIGRAGFKVEPLGLVVWSSLVPPIPFLLLSWRLEGGERMAAALRGFDGQSLFAVAYLAFVATMFGYGLWSRLLARHAAA
KVAPFSLLVPVVGLLASHWLLSETLTPAQLAGSGLLMAGLLATVFGGRLLAAAEGRTRRA
>Mature_299_residues
PLADVAQALAIVLVWGVNFVVIKWGVAGVPPLLLGALRFALVALPAVFVIRRPALPWRYLALYGLTVGVGQFGCLFSAIK
LGMPAGLASVVLQSQAFFTLLLARVFLGERWQASQLVGLLLALGGLALIGMGKGGDMTAVGFGLTIAAATSWAASNVVVR
AIGRAGFKVEPLGLVVWSSLVPPIPFLLLSWRLEGGERMAAALRGFDGQSLFAVAYLAFVATMFGYGLWSRLLARHAAAK
VAPFSLLVPVVGLLASHWLLSETLTPAQLAGSGLLMAGLLATVFGGRLLAAAEGRTRRA

Specific function: May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O- acetyl-L-serine (OAS)), and for other amino acids and their metabolites [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Escherichia coli, GI87081929, Length=275, Percent_Identity=49.0909090909091, Blast_Score=233, Evalue=8e-63,
Organism=Escherichia coli, GI87082351, Length=285, Percent_Identity=27.3684210526316, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 31371; Mature: 31240

Theoretical pI: Translated: 11.75; Mature: 11.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLADVAQALAIVLVWGVNFVVIKWGVAGVPPLLLGALRFALVALPAVFVIRRPALPWRY
CCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LALYGLTVGVGQFGCLFSAIKLGMPAGLASVVLQSQAFFTLLLARVFLGERWQASQLVGL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LLALGGLALIGMGKGGDMTAVGFGLTIAAATSWAASNVVVRAIGRAGFKVEPLGLVVWSS
HHHHHHHHEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHH
LVPPIPFLLLSWRLEGGERMAAALRGFDGQSLFAVAYLAFVATMFGYGLWSRLLARHAAA
HCCHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVAPFSLLVPVVGLLASHWLLSETLTPAQLAGSGLLMAGLLATVFGGRLLAAAEGRTRRA
HHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCEEEECCCCCCCC
>Mature Secondary Structure 
PLADVAQALAIVLVWGVNFVVIKWGVAGVPPLLLGALRFALVALPAVFVIRRPALPWRY
CHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LALYGLTVGVGQFGCLFSAIKLGMPAGLASVVLQSQAFFTLLLARVFLGERWQASQLVGL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LLALGGLALIGMGKGGDMTAVGFGLTIAAATSWAASNVVVRAIGRAGFKVEPLGLVVWSS
HHHHHHHHEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHH
LVPPIPFLLLSWRLEGGERMAAALRGFDGQSLFAVAYLAFVATMFGYGLWSRLLARHAAA
HCCHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVAPFSLLVPVVGLLASHWLLSETLTPAQLAGSGLLMAGLLATVFGGRLLAAAEGRTRRA
HHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 10844694 [H]