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The map label for this gene is cbl [H]

Identifier: 34497282

GI number: 34497282

Start: 1985705

End: 1986634

Strand: Reverse

Name: cbl [H]

Synonym: CV_1827

Alternate gene names: 34497282

Gene position: 1986634-1985705 (Counterclockwise)

Preceding gene: 34497283

Following gene: 34497280

Centisome position: 41.81

GC content: 67.63

Gene sequence:

>930_bases
ATGAACTTCCAGCAGCTGCGCATCATCCGCGAAACCGTGCGCCAGGGTTTCAACCTGACCGAGGTGGCCAACGCGCTGTT
CACCTCGCAGTCCGGCGTCAGCAAGCACATCAAGGACCTGGAGGACGAGCTGGGCGTGGAGCTGTTCATCCGCAAGGGCA
AACGCTTCCTCGGCTTGACCGATCCCGGCAAGGAACTGCTGATCATCGTCGAGCGCATGCTGCTGGACGCCGGCAACATC
AAGCGCCTGGCGCAGCAGTTCAGCCTGCGCGACGAGGGCCAGCTGACCATCGCCACCACCCACACCCAGGCGCGCTACGC
GCTGCCGCAGGTGGTGACCGAGTTCAAGCGCGCCTTCCCACGCGTGCACCTGGTGCTGCACCAGGCCAGCCCGGAGGAGC
TGGTGCGGCTGTTGCTGGCCGGCGACGCCGATATCGGCATCGCCACCGAGGCGGTGACCGAAGTGCCGGAACTGGTGTCC
TTCCCCTACTACAGCTGGCACCACTGCGTGATCGCCCCGCCCGAGCACCCGCTGCACCGCGAGCCGCTGACGCTGGAGGC
GCTGGCCGAGCACCCGATCGTCACCTACCACCACGGTTTCACCGGCCGGGCCAAGATAGACAACACCTTCGCCGAGGCCG
GCCTGGCGCCCGACATCGTGATGGCGGCGCTGGACGCCGATGTGATCAAGACCTATGTCGAGCTGGAGCTGGGCGTCGGC
ATCGTCGCCTCGATGGCGGTGGATCCGCGCCGCGACGCCGGCGTCAAGGTGGTGGAAGGCCCGCCGCTGTTCGGCCAGCA
GACCAGCCGCATCGCGATACGCCGCGGCCATTACCTGCGCAGCTACGCCTACCGCTTCATCGAGCTGTGCGCGCCGGCGC
TGAACGAGCAGAGCGTGCGCCAGGCGCTCAGCCCGGCGCTGCAGGAATAG

Upstream 100 bases:

>100_bases
CCGACGCGCCGCTGCTGGCCGAGCTCGCCGTCGGGCAGGCTGTGCGGCTGCAGGCGCGCGCCGCGCGCGTGTTCGCCGCC
GATCCGCAAGGAGGCGAAGC

Downstream 100 bases:

>100_bases
GCCGCGATCAAAGCCGCCTGAGCAGGCGTTCGGTGCCGGCGCGCGTCGCCACCAGCGCCCGCTCGGCCCGGCCGCGCATG
TCGGCCTCGTAGCGGGCGAC

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNFQQLRIIRETVRQGFNLTEVANALFTSQSGVSKHIKDLEDELGVELFIRKGKRFLGLTDPGKELLIIVERMLLDAGNI
KRLAQQFSLRDEGQLTIATTHTQARYALPQVVTEFKRAFPRVHLVLHQASPEELVRLLLAGDADIGIATEAVTEVPELVS
FPYYSWHHCVIAPPEHPLHREPLTLEALAEHPIVTYHHGFTGRAKIDNTFAEAGLAPDIVMAALDADVIKTYVELELGVG
IVASMAVDPRRDAGVKVVEGPPLFGQQTSRIAIRRGHYLRSYAYRFIELCAPALNEQSVRQALSPALQE

Sequences:

>Translated_309_residues
MNFQQLRIIRETVRQGFNLTEVANALFTSQSGVSKHIKDLEDELGVELFIRKGKRFLGLTDPGKELLIIVERMLLDAGNI
KRLAQQFSLRDEGQLTIATTHTQARYALPQVVTEFKRAFPRVHLVLHQASPEELVRLLLAGDADIGIATEAVTEVPELVS
FPYYSWHHCVIAPPEHPLHREPLTLEALAEHPIVTYHHGFTGRAKIDNTFAEAGLAPDIVMAALDADVIKTYVELELGVG
IVASMAVDPRRDAGVKVVEGPPLFGQQTSRIAIRRGHYLRSYAYRFIELCAPALNEQSVRQALSPALQE
>Mature_309_residues
MNFQQLRIIRETVRQGFNLTEVANALFTSQSGVSKHIKDLEDELGVELFIRKGKRFLGLTDPGKELLIIVERMLLDAGNI
KRLAQQFSLRDEGQLTIATTHTQARYALPQVVTEFKRAFPRVHLVLHQASPEELVRLLLAGDADIGIATEAVTEVPELVS
FPYYSWHHCVIAPPEHPLHREPLTLEALAEHPIVTYHHGFTGRAKIDNTFAEAGLAPDIVMAALDADVIKTYVELELGVG
IVASMAVDPRRDAGVKVVEGPPLFGQQTSRIAIRRGHYLRSYAYRFIELCAPALNEQSVRQALSPALQE

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=310, Percent_Identity=50.9677419354839, Blast_Score=338, Evalue=3e-94,
Organism=Escherichia coli, GI1787530, Length=305, Percent_Identity=45.9016393442623, Blast_Score=277, Evalue=6e-76,
Organism=Escherichia coli, GI1788481, Length=295, Percent_Identity=28.135593220339, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI157672245, Length=275, Percent_Identity=28.7272727272727, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790399, Length=230, Percent_Identity=26.5217391304348, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788887, Length=236, Percent_Identity=30.0847457627119, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367136, Length=222, Percent_Identity=26.1261261261261, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788748, Length=262, Percent_Identity=25.1908396946565, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI87082132, Length=147, Percent_Identity=29.2517006802721, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34437; Mature: 34437

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQQLRIIRETVRQGFNLTEVANALFTSQSGVSKHIKDLEDELGVELFIRKGKRFLGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHCCCEEECCC
DPGKELLIIVERMLLDAGNIKRLAQQFSLRDEGQLTIATTHTQARYALPQVVTEFKRAFP
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCC
RVHLVLHQASPEELVRLLLAGDADIGIATEAVTEVPELVSFPYYSWHHCVIAPPEHPLHR
CEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
EPLTLEALAEHPIVTYHHGFTGRAKIDNTFAEAGLAPDIVMAALDADVIKTYVELELGVG
CCCCHHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCH
IVASMAVDPRRDAGVKVVEGPPLFGQQTSRIAIRRGHYLRSYAYRFIELCAPALNEQSVR
HHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHH
QALSPALQE
HHHHHHHCC
>Mature Secondary Structure
MNFQQLRIIRETVRQGFNLTEVANALFTSQSGVSKHIKDLEDELGVELFIRKGKRFLGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHCCCEEECCC
DPGKELLIIVERMLLDAGNIKRLAQQFSLRDEGQLTIATTHTQARYALPQVVTEFKRAFP
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCC
RVHLVLHQASPEELVRLLLAGDADIGIATEAVTEVPELVSFPYYSWHHCVIAPPEHPLHR
CEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
EPLTLEALAEHPIVTYHHGFTGRAKIDNTFAEAGLAPDIVMAALDADVIKTYVELELGVG
CCCCHHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCH
IVASMAVDPRRDAGVKVVEGPPLFGQQTSRIAIRRGHYLRSYAYRFIELCAPALNEQSVR
HHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHH
QALSPALQE
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]