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The map label for this gene is mmgC [H]

Identifier: 34497240

GI number: 34497240

Start: 1940065

End: 1941849

Strand: Reverse

Name: mmgC [H]

Synonym: CV_1785

Alternate gene names: 34497240

Gene position: 1941849-1940065 (Counterclockwise)

Preceding gene: 34497247

Following gene: 34497239

Centisome position: 40.87

GC content: 65.6

Gene sequence:

>1785_bases
ATGCCTGCTTACAAAGCCCCGCTGCGCGATTTTGACTTCGTTCTCAACGAGCTGATCAAGGTACAGGACATCATCCCCAC
GTTGCCGGGATATGAAGAAGCCACTCAGGACATCTTCAGCGCCTATCTGGAGCAGGCGGCCCAATTCTGCGAATCCGAGC
TCGCCCCGCTCAACCGCCAGGGCGACGAGGAAGGCTGTCACTACGATAGCGCCACCAAGTCCGTCACCACGCCGGCCGGA
TTCAAGGAAGCCTACAAGCAGTATTGCGAGCTGGGCTTCCCCGCGCTGGACTGCGACCCGGCTTATGGCGGCCAGGGCCT
GCCCAAGAGCCTGGGCTTCCCCATCATGGAAATGCAGTGCTCGGCCAACGTGGCGTGGTCGATGTATCCCGGCTTGTCCC
ACGGCGCCTATTCCGCCATCCACGCCCACGGCACCGACGAGCAGAAAGCGGCCTACCTGCCCAAACTGGTGGACGGCAGC
TGGACCGGCACCATGTGCCTGACCGAACCGCACTGCGGCACCGACCTGGGCCTGCTCAAATCCAAGGCGGAACCGCAGGA
AGACGGCAGCTACCGCATCAGCGGCACCAAGATCTTCATCTCCGCCGGCGAGCATGATCTGTCGGAAAACATCATCCACC
TGGTGCTGGCCCGCCTGCCGGACGCGCCCAAGGACGTGAAGGGCATCTCGCTGTTCATCGTGCCCAAGTACCTGGCCGAC
GGCAGCCGCAACGCCGTCGCCTGCGGCAGCCTGGAACACAAGATGGGCATCAAGGCCAACGCCACCGCGGTGATCAATCT
GGACGGCGCCAAGGGCTGGCTGATCGGCGAAGCCAACAAGGGCCTGTCCTGCATGTTCACCATGATGAACGCCGCCCGAC
TGGGCTGCGGCATGCAGGGCCTCGGCCTGGGCGAGGCTTCGTTCCAGGGCGCGCTCGCCTACGCCCGCGAGCGGCTGCAA
ATGCGCGCGCTGAACGGCGCCAAGTGCCCGGACAAGGCGGCCGATCCCATCATCGTCCATCCCGACGTACGCCGCATGCT
GCTGACGCAGAAAGCCTACACCGAAGCCGGCCGCGCGCTGGCCGCCCTGCTGGCGCTGCAGCTGGACATCGAGGACAAGC
ACCCGGACGCCGCCGTCCGCGCCGACGCCGCCGACCTGGTGGCGCTGCTGACCCCGGTGGCCAAGGCCTTCATGACCGAC
AACGGCTTCGTCGCCGCCAACCATGGCGTGCAGGTGTTCGGCGGCCATGGCTACATCCGCGAATGGGGCATGGAACAGCT
GGTGCGCGACGCCCGCATCTCGCAGATCTACGAAGGCACCAACGGCATCCAGGCCATCGACCTGCTGGGCCGCAAGGTGC
TGCTGGACCAAGGCGCCAAACTGCGCAAGTTCACCAAGCTGATCCACACGTTCTGCCAGCGGCACGAAGGCCATCCGCAG
CTGGGCGAGTTCGTCACCCCGCTGGCCAAGCTGATGAAGGAAGTGGGCGAACTGACCATGGGCGTGGGCATGGCCAGCCT
GCAAGACAAGGACGAGGCCGGCGCGGCCGCCGCCGACTACCTGCGCCTGATCGGCCACCTGACCTACGCCTGGCTGTGGG
CGCGCATGGCCGAGGTGTCCTTCGCCAAGCTCGGCCAGGGAGACGACGCGTTCTACCACGCCAAGATCGCCACCGCCCGC
TTCTATTACGCCAAGCTGCTGCCGGAAGCGGAAGCGCTGAAAGCCGGCATCAAGGCCGGCGCCAAGCCCCTGATGGCGCT
GGACGAAGCGCACTTCGCCTTCTAA

Upstream 100 bases:

>100_bases
ACAAACGTTTGAACGAATATCATGGCCCGATCAGGACCCATCATAACAACGTATCGCCCTGGCACGCACCAGGCCGCGCC
CAACCAACTGGAGAAACCGA

Downstream 100 bases:

>100_bases
GCCGCGCCATCCTCCACTCGCAGGCCGCGCCCAGGCGCGGCCTGTGTCATTTTGATCAGCAAAATCACTTACTTGCCTGC
GGCCGCCCCAAGTTTTCGGC

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MPAYKAPLRDFDFVLNELIKVQDIIPTLPGYEEATQDIFSAYLEQAAQFCESELAPLNRQGDEEGCHYDSATKSVTTPAG
FKEAYKQYCELGFPALDCDPAYGGQGLPKSLGFPIMEMQCSANVAWSMYPGLSHGAYSAIHAHGTDEQKAAYLPKLVDGS
WTGTMCLTEPHCGTDLGLLKSKAEPQEDGSYRISGTKIFISAGEHDLSENIIHLVLARLPDAPKDVKGISLFIVPKYLAD
GSRNAVACGSLEHKMGIKANATAVINLDGAKGWLIGEANKGLSCMFTMMNAARLGCGMQGLGLGEASFQGALAYARERLQ
MRALNGAKCPDKAADPIIVHPDVRRMLLTQKAYTEAGRALAALLALQLDIEDKHPDAAVRADAADLVALLTPVAKAFMTD
NGFVAANHGVQVFGGHGYIREWGMEQLVRDARISQIYEGTNGIQAIDLLGRKVLLDQGAKLRKFTKLIHTFCQRHEGHPQ
LGEFVTPLAKLMKEVGELTMGVGMASLQDKDEAGAAAADYLRLIGHLTYAWLWARMAEVSFAKLGQGDDAFYHAKIATAR
FYYAKLLPEAEALKAGIKAGAKPLMALDEAHFAF

Sequences:

>Translated_594_residues
MPAYKAPLRDFDFVLNELIKVQDIIPTLPGYEEATQDIFSAYLEQAAQFCESELAPLNRQGDEEGCHYDSATKSVTTPAG
FKEAYKQYCELGFPALDCDPAYGGQGLPKSLGFPIMEMQCSANVAWSMYPGLSHGAYSAIHAHGTDEQKAAYLPKLVDGS
WTGTMCLTEPHCGTDLGLLKSKAEPQEDGSYRISGTKIFISAGEHDLSENIIHLVLARLPDAPKDVKGISLFIVPKYLAD
GSRNAVACGSLEHKMGIKANATAVINLDGAKGWLIGEANKGLSCMFTMMNAARLGCGMQGLGLGEASFQGALAYARERLQ
MRALNGAKCPDKAADPIIVHPDVRRMLLTQKAYTEAGRALAALLALQLDIEDKHPDAAVRADAADLVALLTPVAKAFMTD
NGFVAANHGVQVFGGHGYIREWGMEQLVRDARISQIYEGTNGIQAIDLLGRKVLLDQGAKLRKFTKLIHTFCQRHEGHPQ
LGEFVTPLAKLMKEVGELTMGVGMASLQDKDEAGAAAADYLRLIGHLTYAWLWARMAEVSFAKLGQGDDAFYHAKIATAR
FYYAKLLPEAEALKAGIKAGAKPLMALDEAHFAF
>Mature_593_residues
PAYKAPLRDFDFVLNELIKVQDIIPTLPGYEEATQDIFSAYLEQAAQFCESELAPLNRQGDEEGCHYDSATKSVTTPAGF
KEAYKQYCELGFPALDCDPAYGGQGLPKSLGFPIMEMQCSANVAWSMYPGLSHGAYSAIHAHGTDEQKAAYLPKLVDGSW
TGTMCLTEPHCGTDLGLLKSKAEPQEDGSYRISGTKIFISAGEHDLSENIIHLVLARLPDAPKDVKGISLFIVPKYLADG
SRNAVACGSLEHKMGIKANATAVINLDGAKGWLIGEANKGLSCMFTMMNAARLGCGMQGLGLGEASFQGALAYARERLQM
RALNGAKCPDKAADPIIVHPDVRRMLLTQKAYTEAGRALAALLALQLDIEDKHPDAAVRADAADLVALLTPVAKAFMTDN
GFVAANHGVQVFGGHGYIREWGMEQLVRDARISQIYEGTNGIQAIDLLGRKVLLDQGAKLRKFTKLIHTFCQRHEGHPQL
GEFVTPLAKLMKEVGELTMGVGMASLQDKDEAGAAAADYLRLIGHLTYAWLWARMAEVSFAKLGQGDDAFYHAKIATARF
YYAKLLPEAEALKAGIKAGAKPLMALDEAHFAF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=436, Percent_Identity=26.605504587156, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI4501859, Length=401, Percent_Identity=25.9351620947631, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4557235, Length=421, Percent_Identity=26.1282660332542, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI76496475, Length=421, Percent_Identity=26.1282660332542, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI7656849, Length=379, Percent_Identity=28.7598944591029, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4557233, Length=413, Percent_Identity=26.8765133171913, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4501857, Length=384, Percent_Identity=27.8645833333333, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI226958412, Length=447, Percent_Identity=25.9507829977629, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI4557231, Length=311, Percent_Identity=27.9742765273312, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI187960098, Length=311, Percent_Identity=27.9742765273312, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI226958414, Length=381, Percent_Identity=26.7716535433071, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI4503943, Length=325, Percent_Identity=26.4615384615385, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI7669494, Length=188, Percent_Identity=28.7234042553192, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI87082384, Length=287, Percent_Identity=30.3135888501742, Blast_Score=123, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17534899, Length=381, Percent_Identity=28.8713910761155, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17533517, Length=435, Percent_Identity=27.1264367816092, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17508101, Length=409, Percent_Identity=25.6723716381418, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=29.023746701847, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71985184, Length=367, Percent_Identity=26.158038147139, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=407, Percent_Identity=26.044226044226, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI86563383, Length=297, Percent_Identity=28.6195286195286, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI86563381, Length=297, Percent_Identity=28.6195286195286, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17570075, Length=387, Percent_Identity=25.3229974160207, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=181, Percent_Identity=35.3591160220994, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=224, Percent_Identity=29.9107142857143, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17538396, Length=410, Percent_Identity=23.9024390243902, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=240, Percent_Identity=27.0833333333333, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=285, Percent_Identity=27.3684210526316, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24646207, Length=415, Percent_Identity=25.5421686746988, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281363737, Length=369, Percent_Identity=27.10027100271, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21356377, Length=372, Percent_Identity=26.6129032258064, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24666513, Length=407, Percent_Identity=25.7985257985258, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355753, Length=417, Percent_Identity=26.1390887290168, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24660351, Length=309, Percent_Identity=28.8025889967638, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 64291; Mature: 64160

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAYKAPLRDFDFVLNELIKVQDIIPTLPGYEEATQDIFSAYLEQAAQFCESELAPLNRQ
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GDEEGCHYDSATKSVTTPAGFKEAYKQYCELGFPALDCDPAYGGQGLPKSLGFPIMEMQC
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCEEEEEE
SANVAWSMYPGLSHGAYSAIHAHGTDEQKAAYLPKLVDGSWTGTMCLTEPHCGTDLGLLK
CCCEEEEECCCCCCCCCCEEECCCCCHHHHHHCCHHCCCCCCCEEEEECCCCCCCHHHHH
SKAEPQEDGSYRISGTKIFISAGEHDLSENIIHLVLARLPDAPKDVKGISLFIVPKYLAD
CCCCCCCCCCEEEECEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHCC
GSRNAVACGSLEHKMGIKANATAVINLDGAKGWLIGEANKGLSCMFTMMNAARLGCGMQG
CCCCEEEECCCHHHCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCC
LGLGEASFQGALAYARERLQMRALNGAKCPDKAADPIIVHPDVRRMLLTQKAYTEAGRAL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHH
AALLALQLDIEDKHPDAAVRADAADLVALLTPVAKAFMTDNGFVAANHGVQVFGGHGYIR
HHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCHHH
EWGMEQLVRDARISQIYEGTNGIQAIDLLGRKVLLDQGAKLRKFTKLIHTFCQRHEGHPQ
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
LGEFVTPLAKLMKEVGELTMGVGMASLQDKDEAGAAAADYLRLIGHLTYAWLWARMAEVS
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FAKLGQGDDAFYHAKIATARFYYAKLLPEAEALKAGIKAGAKPLMALDEAHFAF
HHHCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure 
PAYKAPLRDFDFVLNELIKVQDIIPTLPGYEEATQDIFSAYLEQAAQFCESELAPLNRQ
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GDEEGCHYDSATKSVTTPAGFKEAYKQYCELGFPALDCDPAYGGQGLPKSLGFPIMEMQC
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCEEEEEE
SANVAWSMYPGLSHGAYSAIHAHGTDEQKAAYLPKLVDGSWTGTMCLTEPHCGTDLGLLK
CCCEEEEECCCCCCCCCCEEECCCCCHHHHHHCCHHCCCCCCCEEEEECCCCCCCHHHHH
SKAEPQEDGSYRISGTKIFISAGEHDLSENIIHLVLARLPDAPKDVKGISLFIVPKYLAD
CCCCCCCCCCEEEECEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHCC
GSRNAVACGSLEHKMGIKANATAVINLDGAKGWLIGEANKGLSCMFTMMNAARLGCGMQG
CCCCEEEECCCHHHCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCC
LGLGEASFQGALAYARERLQMRALNGAKCPDKAADPIIVHPDVRRMLLTQKAYTEAGRAL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHH
AALLALQLDIEDKHPDAAVRADAADLVALLTPVAKAFMTDNGFVAANHGVQVFGGHGYIR
HHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCHHH
EWGMEQLVRDARISQIYEGTNGIQAIDLLGRKVLLDQGAKLRKFTKLIHTFCQRHEGHPQ
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
LGEFVTPLAKLMKEVGELTMGVGMASLQDKDEAGAAAADYLRLIGHLTYAWLWARMAEVS
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FAKLGQGDDAFYHAKIATARFYYAKLLPEAEALKAGIKAGAKPLMALDEAHFAF
HHHCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]