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The map label for this gene is trpS1 [H]

Identifier: 34497152

GI number: 34497152

Start: 1834572

End: 1835768

Strand: Direct

Name: trpS1 [H]

Synonym: CV_1697

Alternate gene names: 34497152

Gene position: 1834572-1835768 (Clockwise)

Preceding gene: 34497151

Following gene: 34497156

Centisome position: 38.61

GC content: 65.5

Gene sequence:

>1197_bases
ATGTCCGCCAACCGCATTCTCTCCGGCATGCGCCCCACCGGCAGCCTGCACCTTGGCCATTACCACGGCGTGATCAAGAA
TTGGGTGGAGCTGCAGCACAGCCACGAATGCTTCTTCATGGTGGCCGACTGGCACGCGCTGACCACCAATTTCGACGACG
TGTCCATCATCGGCAAGTCCATCGACGAGATGGTCATCGACTGGCTGGCCTCCGGCGTCGACCCGGAAAAATCCACCGTC
TTCGTCCAATCCAAGGTGCCGCAGCACGCCGAGCTGCACCTGGCGCTGTCCATGGTGACGCCGCTGTCCTGGCTGGAACG
GGTGCCGACCTACAAGGACCAGATGGAGAAGCTCAGCCACAAGGACCTGACCACCTACGGCTTCCTCGGCTATCCGCTGC
TGCAGGCCGCCGACATCCTGGTGTACAAGGCCGGGCTGGTGCCGGTTGGCGAGGACCAGGTGCCGCACATCGAGCTGACC
CGCGAAGTGGCGCGCCGCTTCAACCACATGTTCGGCCGCGAGCCCAACTTCGAAGAGCTGGCCCGCGCCGCGGTGAAGAA
AATCGGCAAGGCGGGCAAGGATTTCGATCGTTTGCGCACCGCTTACCTGCAGGACGGCGACGCCGGCGCGCTGGAGAAGG
CGCGCGAAATCCTGGCGGCCAGCCAGAACCTGGGCGCGGCCGATCGCGAGCGGCTGCACGGCTGGCTGGAAAACAAGGGC
AAGACCATCCTGCCGGAGTGCGAGGCCAAGCTGACCGCCGCGTCCAAGATGCCGGGTCTGGACGGCCAGAAGATGTCCAA
GTCCTACGGCAACACAATCACCATGCGCGAAGCGCCGGAAACCGTGAGCAAGAAGATCCGCGGCATGCCGACCGATCCGG
CCCGCGTGCGCCGCACCGACCCGGGCACGCCGAGCCTTTGCCCGGTATGGCAGCTGCACGAGGTGTACAGCGACGGCGAG
ACCAAGGAATGGGTGAAGGCGGGCTGTACCAGCGCCGGCATCGGCTGCCTGGACTGCAAGCAGCCGGTGATCGACGCCGT
GGTGCGCGAGCAGCAGCCGATGTTCGAGCGCGCGGAGAAGTATCTGGCCAATCCGAAGCTGGTCGCCGAAATCCTGGCCG
ACGGCAACGCCCGCGCCGAGAAGGTGGCGCGCGAAACGATGAACGACGTGCGCGCCGCGATGGGCCTCGGCTATTGA

Upstream 100 bases:

>100_bases
TATCATCTGCTGCAACTGTTTTTCTAGAACCCTGAGCGGGCCTGGCCGCCGGATGGTGCCGGCGGCTTTTCATTTCCCGC
GCAACCGAGAGCATAACAAT

Downstream 100 bases:

>100_bases
TGCCGCTCTGTCCGCGCCATGGACGGGAGAAATGAAAAACGGGCCGCGATCATGCGGTCCGTTTTTTTTTGCGGCTGGGC
GGTTCAGCTCTGCTGCAGCA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSANRILSGMRPTGSLHLGHYHGVIKNWVELQHSHECFFMVADWHALTTNFDDVSIIGKSIDEMVIDWLASGVDPEKSTV
FVQSKVPQHAELHLALSMVTPLSWLERVPTYKDQMEKLSHKDLTTYGFLGYPLLQAADILVYKAGLVPVGEDQVPHIELT
REVARRFNHMFGREPNFEELARAAVKKIGKAGKDFDRLRTAYLQDGDAGALEKAREILAASQNLGAADRERLHGWLENKG
KTILPECEAKLTAASKMPGLDGQKMSKSYGNTITMREAPETVSKKIRGMPTDPARVRRTDPGTPSLCPVWQLHEVYSDGE
TKEWVKAGCTSAGIGCLDCKQPVIDAVVREQQPMFERAEKYLANPKLVAEILADGNARAEKVARETMNDVRAAMGLGY

Sequences:

>Translated_398_residues
MSANRILSGMRPTGSLHLGHYHGVIKNWVELQHSHECFFMVADWHALTTNFDDVSIIGKSIDEMVIDWLASGVDPEKSTV
FVQSKVPQHAELHLALSMVTPLSWLERVPTYKDQMEKLSHKDLTTYGFLGYPLLQAADILVYKAGLVPVGEDQVPHIELT
REVARRFNHMFGREPNFEELARAAVKKIGKAGKDFDRLRTAYLQDGDAGALEKAREILAASQNLGAADRERLHGWLENKG
KTILPECEAKLTAASKMPGLDGQKMSKSYGNTITMREAPETVSKKIRGMPTDPARVRRTDPGTPSLCPVWQLHEVYSDGE
TKEWVKAGCTSAGIGCLDCKQPVIDAVVREQQPMFERAEKYLANPKLVAEILADGNARAEKVARETMNDVRAAMGLGY
>Mature_397_residues
SANRILSGMRPTGSLHLGHYHGVIKNWVELQHSHECFFMVADWHALTTNFDDVSIIGKSIDEMVIDWLASGVDPEKSTVF
VQSKVPQHAELHLALSMVTPLSWLERVPTYKDQMEKLSHKDLTTYGFLGYPLLQAADILVYKAGLVPVGEDQVPHIELTR
EVARRFNHMFGREPNFEELARAAVKKIGKAGKDFDRLRTAYLQDGDAGALEKAREILAASQNLGAADRERLHGWLENKGK
TILPECEAKLTAASKMPGLDGQKMSKSYGNTITMREAPETVSKKIRGMPTDPARVRRTDPGTPSLCPVWQLHEVYSDGET
KEWVKAGCTSAGIGCLDCKQPVIDAVVREQQPMFERAEKYLANPKLVAEILADGNARAEKVARETMNDVRAAMGLGY

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=224, Percent_Identity=38.3928571428571, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI41352700, Length=172, Percent_Identity=43.0232558139535, Blast_Score=138, Evalue=8e-33,
Organism=Escherichia coli, GI1789786, Length=172, Percent_Identity=41.2790697674419, Blast_Score=154, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI71982800, Length=188, Percent_Identity=37.2340425531915, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71982793, Length=188, Percent_Identity=37.2340425531915, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320474, Length=187, Percent_Identity=41.1764705882353, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24666151, Length=398, Percent_Identity=29.1457286432161, Blast_Score=159, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 44222; Mature: 44091

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANRILSGMRPTGSLHLGHYHGVIKNWVELQHSHECFFMVADWHALTTNFDDVSIIGKS
CCCHHHHHCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCHHHHHHHH
IDEMVIDWLASGVDPEKSTVFVQSKVPQHAELHLALSMVTPLSWLERVPTYKDQMEKLSH
HHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KDLTTYGFLGYPLLQAADILVYKAGLVPVGEDQVPHIELTREVARRFNHMFGREPNFEEL
CCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
ARAAVKKIGKAGKDFDRLRTAYLQDGDAGALEKAREILAASQNLGAADRERLHGWLENKG
HHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
KTILPECEAKLTAASKMPGLDGQKMSKSYGNTITMREAPETVSKKIRGMPTDPARVRRTD
CEECCCHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCCHHHHHHHHCCCCCCHHHCCCCC
PGTPSLCPVWQLHEVYSDGETKEWVKAGCTSAGIGCLDCKQPVIDAVVREQQPMFERAEK
CCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
YLANPKLVAEILADGNARAEKVARETMNDVRAAMGLGY
HHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SANRILSGMRPTGSLHLGHYHGVIKNWVELQHSHECFFMVADWHALTTNFDDVSIIGKS
CCHHHHHCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCHHHHHHHH
IDEMVIDWLASGVDPEKSTVFVQSKVPQHAELHLALSMVTPLSWLERVPTYKDQMEKLSH
HHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KDLTTYGFLGYPLLQAADILVYKAGLVPVGEDQVPHIELTREVARRFNHMFGREPNFEEL
CCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
ARAAVKKIGKAGKDFDRLRTAYLQDGDAGALEKAREILAASQNLGAADRERLHGWLENKG
HHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
KTILPECEAKLTAASKMPGLDGQKMSKSYGNTITMREAPETVSKKIRGMPTDPARVRRTD
CEECCCHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCCHHHHHHHHCCCCCCHHHCCCCC
PGTPSLCPVWQLHEVYSDGETKEWVKAGCTSAGIGCLDCKQPVIDAVVREQQPMFERAEK
CCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
YLANPKLVAEILADGNARAEKVARETMNDVRAAMGLGY
HHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]