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The map label for this gene is ydeP [H]

Identifier: 34497077

GI number: 34497077

Start: 1756853

End: 1759156

Strand: Reverse

Name: ydeP [H]

Synonym: CV_1622

Alternate gene names: 34497077

Gene position: 1759156-1756853 (Counterclockwise)

Preceding gene: 34497080

Following gene: 34497071

Centisome position: 37.03

GC content: 67.84

Gene sequence:

>2304_bases
ATGAGCCATTCCAAGACCAGCGAACGCATCCAGCCGTACGCGCAGCCGGCCGGCGGGCTGGATTCCATCAAAAGCACCAC
CGTTTCGCTGCTCAAGGAAAAGGTGCCGGGCAGCCGGTATAAGACGCTGTTCCACCAGAACCAGCCCGACGGCTTCGACT
GCCCGGGCTGCGCCTGGCCGGATCGGGAACATACCTCCACCTTCGAATTCTGCGAGAACGGCGTCAAGGCGGTGGCGGCC
GAGGCCACCTCCAAGCGCATCGGCGCCGATTTCTTCGCGCGGCATAGCGTGGCCCAGCTGCTGGAACAGAGCGATTACGA
GCTGGAGCAACACGGCCGCCTGACCGAGCCGCTGGCCTACGACGCGGCCAGCGACCGCTACCTGCCGATTGCCTGGAGCG
ACGCCTACGCCCGGATCGCCGGCCATCTGAAGGCCTTGCCCGATCCCAACCAGGCCTCGTTCTACGTCTCCGGCCGCACC
AGCAACGAAACCGCCTTCCTGTTCCAGCTGTTCGTGCGCCTGTACGGCACCAACAACTTCCCGGACTGCTCCAACCTCTG
CCACGAATCGTCCAGCCGCGCGCTGCCGCAAACGGTGGGCGTGGGCAAGGCCACGGTGGTGCTGGAGGACTTCGAGCACG
CCGACACCATCATGGTGTTCGGCCAGAACCCGGCCACCAACCATCCGCGCATGCTGAACGAGCTGCGAGCCGCCGCCAAG
CGCGGCGCGACCATCGTCTCGATCAATCCGCTGAAGGAAAAAGGCCTGGACCGCTTCGCCAGCCCGCAGCATCCGCTGGA
TCTGGTCAACGGCGGCGCCGAGATCAGCTCGCTGTTCATCCGCCCCACGCTGGGCGGCGACTTCGCGCTGATCAAGGGCG
TGGCCAAACGCGTGCTGGAACTGGACGACGCGGCCGTCGCCGCCGGCGGCGAGCGGATTCTGGACATCGGCTTCCTGGCC
GAGCACTGTTCCGGCTTCGACGCCTTCGCCGCCGACCTGCGCGCCGAGAGCTGGCCGGACCTGGCCGCCGCCTCCGGCGT
GCCCTACCAGGATATCGACGCGCTGGCCCGGGTGTACGCGAAAGGCAAGGCGGTGATCGCCACCTGGGGCATGGGCCTGA
CCCAGCACCGCGATTCGGTGGCGGCGATCCAGATGCTGTCCAACCTGATGATGATGCGCGGCAACATCGGCCGCCTCGGC
GCCGGCCTGTGTCCGGTGCGCGGCCACTCCAATGTGCAGGGCGACCGCACCATGGGCATCGAGGACAAGCCCGCCCCGGC
CTTCCTCGACCGGCTGCGCGATGTCTACGGCTTCGAACCGCCGCGCGGGCACGGCCTGGACGCGGTGGACACCATCAAGG
CGATGCTGGACGGGCGGGTCAAGGTCTTCGTCGGCCTGGGCGGCAATTTCGCGATGGCGACGCCGGACACGCCGCGCACC
TTCGAAGCGCTGCGCAACTGCGATCTGACCGTGCAGATTTCCACCAAGCTGAACCGCAGCCACCTGATCCACGGCCGGGA
CGCGCTGATCCTGCCGACGCTGGGCCGCACCGAGATCGATCTGCAGAAAACCGGCCCACAGGGCGTGACGGTGGAGGACT
CGATGTGCATGGTGCACTTGTCCTACGGCATCAACCCGCCGGCCTCGAAGCAGCTGCGCTCGGAAACCGCCATCGTCGCC
GGCATCGCCGACGCGACGCTGGGCGGCGGGAAAATAGACTGGCTGTCCTATGCGGACGATTACGCCAAAATCCGCGACGA
GATCGCCAAGGCCGTCGCCGGCTTTGAAGATTTCAATGCCCGCGTGGCCAAGCCCGGCGGCTTCCACCTGACGCCGGCCT
CGCGCGAGCGGCGCTGGCTGACGCCCGACGGCAAAGCGCGATTCATCGTCAACGCGCTGGAGAAGGACACGCCGATCGCC
CGCGCCCGCGCGCTGCACGGCGACCGGTTGATGGTGCTGATGACCGCCCGCTCCCACGACCAGTACAACACCACCATCTA
CGCGCTGGACGACCGCTACCGCGGCGTCTACGGCCAGCGCCGGGTGCTGCTGATCAACCGGGATGACATCGCGCGGCTGG
GCTTCGCCGACGGCGAGCGGGTGGACCTCTTCACCGTCTGGCACGATGGGATAGAGCGCCGCGCCGACGGCTTCCGGCTG
GTGGAGTACGACATCCCGCGCGGCTGCCTGGGCGCCTACTTTCCCGAGACCAACCCGCTGATCCCGCTGGACAGCGTGGC
CGGCGTCTCCAACACGCCCACGTCCAAGTCGGTGCCGGTGCTGCTGCGGCGCTCGGCCGGCTGA

Upstream 100 bases:

>100_bases
GCAAGGAATTTGACCGTGATCCGCCGCCATCCTTTATCCTTGCATCGATTGACCCAAAGCAAAACCGGAACCACACCTTT
CCCGCAGGAGCCGCCCCGAC

Downstream 100 bases:

>100_bases
CGCCTGCCGCCCGCAGGCCGGCCTCGGTCCGGCCTGCTCAGTCCGCCAATGCCAGCAGCTCCCGGACGATGGCGATCGCC
TGCTCGAACTGCAGCCGTTG

Product: formate dehydrogenase

Products: CO2; NADH

Alternate protein names: NA

Number of amino acids: Translated: 767; Mature: 766

Protein sequence:

>767_residues
MSHSKTSERIQPYAQPAGGLDSIKSTTVSLLKEKVPGSRYKTLFHQNQPDGFDCPGCAWPDREHTSTFEFCENGVKAVAA
EATSKRIGADFFARHSVAQLLEQSDYELEQHGRLTEPLAYDAASDRYLPIAWSDAYARIAGHLKALPDPNQASFYVSGRT
SNETAFLFQLFVRLYGTNNFPDCSNLCHESSSRALPQTVGVGKATVVLEDFEHADTIMVFGQNPATNHPRMLNELRAAAK
RGATIVSINPLKEKGLDRFASPQHPLDLVNGGAEISSLFIRPTLGGDFALIKGVAKRVLELDDAAVAAGGERILDIGFLA
EHCSGFDAFAADLRAESWPDLAAASGVPYQDIDALARVYAKGKAVIATWGMGLTQHRDSVAAIQMLSNLMMMRGNIGRLG
AGLCPVRGHSNVQGDRTMGIEDKPAPAFLDRLRDVYGFEPPRGHGLDAVDTIKAMLDGRVKVFVGLGGNFAMATPDTPRT
FEALRNCDLTVQISTKLNRSHLIHGRDALILPTLGRTEIDLQKTGPQGVTVEDSMCMVHLSYGINPPASKQLRSETAIVA
GIADATLGGGKIDWLSYADDYAKIRDEIAKAVAGFEDFNARVAKPGGFHLTPASRERRWLTPDGKARFIVNALEKDTPIA
RARALHGDRLMVLMTARSHDQYNTTIYALDDRYRGVYGQRRVLLINRDDIARLGFADGERVDLFTVWHDGIERRADGFRL
VEYDIPRGCLGAYFPETNPLIPLDSVAGVSNTPTSKSVPVLLRRSAG

Sequences:

>Translated_767_residues
MSHSKTSERIQPYAQPAGGLDSIKSTTVSLLKEKVPGSRYKTLFHQNQPDGFDCPGCAWPDREHTSTFEFCENGVKAVAA
EATSKRIGADFFARHSVAQLLEQSDYELEQHGRLTEPLAYDAASDRYLPIAWSDAYARIAGHLKALPDPNQASFYVSGRT
SNETAFLFQLFVRLYGTNNFPDCSNLCHESSSRALPQTVGVGKATVVLEDFEHADTIMVFGQNPATNHPRMLNELRAAAK
RGATIVSINPLKEKGLDRFASPQHPLDLVNGGAEISSLFIRPTLGGDFALIKGVAKRVLELDDAAVAAGGERILDIGFLA
EHCSGFDAFAADLRAESWPDLAAASGVPYQDIDALARVYAKGKAVIATWGMGLTQHRDSVAAIQMLSNLMMMRGNIGRLG
AGLCPVRGHSNVQGDRTMGIEDKPAPAFLDRLRDVYGFEPPRGHGLDAVDTIKAMLDGRVKVFVGLGGNFAMATPDTPRT
FEALRNCDLTVQISTKLNRSHLIHGRDALILPTLGRTEIDLQKTGPQGVTVEDSMCMVHLSYGINPPASKQLRSETAIVA
GIADATLGGGKIDWLSYADDYAKIRDEIAKAVAGFEDFNARVAKPGGFHLTPASRERRWLTPDGKARFIVNALEKDTPIA
RARALHGDRLMVLMTARSHDQYNTTIYALDDRYRGVYGQRRVLLINRDDIARLGFADGERVDLFTVWHDGIERRADGFRL
VEYDIPRGCLGAYFPETNPLIPLDSVAGVSNTPTSKSVPVLLRRSAG
>Mature_766_residues
SHSKTSERIQPYAQPAGGLDSIKSTTVSLLKEKVPGSRYKTLFHQNQPDGFDCPGCAWPDREHTSTFEFCENGVKAVAAE
ATSKRIGADFFARHSVAQLLEQSDYELEQHGRLTEPLAYDAASDRYLPIAWSDAYARIAGHLKALPDPNQASFYVSGRTS
NETAFLFQLFVRLYGTNNFPDCSNLCHESSSRALPQTVGVGKATVVLEDFEHADTIMVFGQNPATNHPRMLNELRAAAKR
GATIVSINPLKEKGLDRFASPQHPLDLVNGGAEISSLFIRPTLGGDFALIKGVAKRVLELDDAAVAAGGERILDIGFLAE
HCSGFDAFAADLRAESWPDLAAASGVPYQDIDALARVYAKGKAVIATWGMGLTQHRDSVAAIQMLSNLMMMRGNIGRLGA
GLCPVRGHSNVQGDRTMGIEDKPAPAFLDRLRDVYGFEPPRGHGLDAVDTIKAMLDGRVKVFVGLGGNFAMATPDTPRTF
EALRNCDLTVQISTKLNRSHLIHGRDALILPTLGRTEIDLQKTGPQGVTVEDSMCMVHLSYGINPPASKQLRSETAIVAG
IADATLGGGKIDWLSYADDYAKIRDEIAKAVAGFEDFNARVAKPGGFHLTPASRERRWLTPDGKARFIVNALEKDTPIAR
ARALHGDRLMVLMTARSHDQYNTTIYALDDRYRGVYGQRRVLLINRDDIARLGFADGERVDLFTVWHDGIERRADGFRLV
EYDIPRGCLGAYFPETNPLIPLDSVAGVSNTPTSKSVPVLLRRSAG

Specific function: Probably involved in acid resistance [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787778, Length=761, Percent_Identity=47.568988173456, Blast_Score=734, Evalue=0.0,
Organism=Escherichia coli, GI3868721, Length=322, Percent_Identity=29.5031055900621, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1788534, Length=406, Percent_Identity=25.3694581280788, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR010046 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.2.1.2

Molecular weight: Translated: 83704; Mature: 83573

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSKTSERIQPYAQPAGGLDSIKSTTVSLLKEKVPGSRYKTLFHQNQPDGFDCPGCAWP
CCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCC
DREHTSTFEFCENGVKAVAAEATSKRIGADFFARHSVAQLLEQSDYELEQHGRLTEPLAY
CCCCCHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCC
DAASDRYLPIAWSDAYARIAGHLKALPDPNQASFYVSGRTSNETAFLFQLFVRLYGTNNF
CCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCC
PDCSNLCHESSSRALPQTVGVGKATVVLEDFEHADTIMVFGQNPATNHPRMLNELRAAAK
CCHHHHHHCCCCCCCCHHCCCCCEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
RGATIVSINPLKEKGLDRFASPQHPLDLVNGGAEISSLFIRPTLGGDFALIKGVAKRVLE
CCCEEEEECCHHHHCHHHHCCCCCCHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHH
LDDAAVAAGGERILDIGFLAEHCSGFDAFAADLRAESWPDLAAASGVPYQDIDALARVYA
HCCHHHHCCCCEEEEHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHH
KGKAVIATWGMGLTQHRDSVAAIQMLSNLMMMRGNIGRLGAGLCPVRGHSNVQGDRTMGI
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EDKPAPAFLDRLRDVYGFEPPRGHGLDAVDTIKAMLDGRVKVFVGLGGNFAMATPDTPRT
CCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCEEECCCCCCHH
FEALRNCDLTVQISTKLNRSHLIHGRDALILPTLGRTEIDLQKTGPQGVTVEDSMCMVHL
HHHHHCCCEEEEEECCCCCHHEECCCCEEEEECCCCCEEEEECCCCCCCEEECCEEEEEE
SYGINPPASKQLRSETAIVAGIADATLGGGKIDWLSYADDYAKIRDEIAKAVAGFEDFNA
ECCCCCCHHHHHHHCCEEEEECHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCHHHCCC
RVAKPGGFHLTPASRERRWLTPDGKARFIVNALEKDTPIARARALHGDRLMVLMTARSHD
EEECCCCEECCCCCCCCCCCCCCCCCEEEEEHHHCCCCHHHHHHCCCCEEEEEEEECCCC
QYNTTIYALDDRYRGVYGQRRVLLINRDDIARLGFADGERVDLFTVWHDGIERRADGFRL
CCCCEEEEECCCCCCCCCCCEEEEECCCCHHHCCCCCCCEEEEEEEEHHHHHHCCCCCEE
VEYDIPRGCLGAYFPETNPLIPLDSVAGVSNTPTSKSVPVLLRRSAG
EEECCCCCHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCEEEECCCC
>Mature Secondary Structure 
SHSKTSERIQPYAQPAGGLDSIKSTTVSLLKEKVPGSRYKTLFHQNQPDGFDCPGCAWP
CCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCC
DREHTSTFEFCENGVKAVAAEATSKRIGADFFARHSVAQLLEQSDYELEQHGRLTEPLAY
CCCCCHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCC
DAASDRYLPIAWSDAYARIAGHLKALPDPNQASFYVSGRTSNETAFLFQLFVRLYGTNNF
CCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCC
PDCSNLCHESSSRALPQTVGVGKATVVLEDFEHADTIMVFGQNPATNHPRMLNELRAAAK
CCHHHHHHCCCCCCCCHHCCCCCEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
RGATIVSINPLKEKGLDRFASPQHPLDLVNGGAEISSLFIRPTLGGDFALIKGVAKRVLE
CCCEEEEECCHHHHCHHHHCCCCCCHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHH
LDDAAVAAGGERILDIGFLAEHCSGFDAFAADLRAESWPDLAAASGVPYQDIDALARVYA
HCCHHHHCCCCEEEEHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHH
KGKAVIATWGMGLTQHRDSVAAIQMLSNLMMMRGNIGRLGAGLCPVRGHSNVQGDRTMGI
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EDKPAPAFLDRLRDVYGFEPPRGHGLDAVDTIKAMLDGRVKVFVGLGGNFAMATPDTPRT
CCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCEEECCCCCCHH
FEALRNCDLTVQISTKLNRSHLIHGRDALILPTLGRTEIDLQKTGPQGVTVEDSMCMVHL
HHHHHCCCEEEEEECCCCCHHEECCCCEEEEECCCCCEEEEECCCCCCCEEECCEEEEEE
SYGINPPASKQLRSETAIVAGIADATLGGGKIDWLSYADDYAKIRDEIAKAVAGFEDFNA
ECCCCCCHHHHHHHCCEEEEECHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCHHHCCC
RVAKPGGFHLTPASRERRWLTPDGKARFIVNALEKDTPIARARALHGDRLMVLMTARSHD
EEECCCCEECCCCCCCCCCCCCCCCCEEEEEHHHCCCCHHHHHHCCCCEEEEEEEECCCC
QYNTTIYALDDRYRGVYGQRRVLLINRDDIARLGFADGERVDLFTVWHDGIERRADGFRL
CCCCEEEEECCCCCCCCCCCEEEEECCCCHHHCCCCCCCEEEEEEEEHHHHHHCCCCCEE
VEYDIPRGCLGAYFPETNPLIPLDSVAGVSNTPTSKSVPVLLRRSAG
EEECCCCCHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]