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The map label for this gene is lolA

Identifier: 34497069

GI number: 34497069

Start: 1741285

End: 1741905

Strand: Reverse

Name: lolA

Synonym: CV_1614

Alternate gene names: 34497069

Gene position: 1741905-1741285 (Counterclockwise)

Preceding gene: 34497070

Following gene: 34497062

Centisome position: 36.66

GC content: 66.34

Gene sequence:

>621_bases
ATGAAACCGCTTTTCCCCATGCTGACCGCCGCCGCCATCGCCGCTGGCCTGGCCGCCCCGGCTCAAGCCTCCGCCGTCGC
CCAGCTCAAGGCCTTCGTGTCCGGCAGCAAGACCCTGTCGGCAGATTTCAACCAGACCGTGACCAACAAGGGCAAGCGCG
AAGAGGCCAGCGGCCGGCTGGAGATCGCCCGCCCGGGGAAATTCCGCTGGGAATACACCAAACCCTACGCCCAACTGATC
GTCGGCGACGGCAAGACGCTGTGGATCTACGACCAGGACCTCGCCCAGGTAACCCGCAAGGCCCAGGGCGCCGCGCTGGG
CTCCAGCCCGGCCGCGCTGCTGGCCGGCAACAATGAAATCGAGCGCAGCTACAAGCTGAACGAGGCCGGCAAGCAGGGCG
ACCTGGAATGGCTGGCCGCCAGCCCGAAAAAGCAGGACAACACCTTCAGCGCCATCCGCATGGGCTTCAAGAACAATGTG
CTGGTGGAAATGCAGCTGACCGACAGCTTCGGCAACGACACCCGCATCGTGTTCAGCCAGCAGCGGCAGAACGCCGCGCT
GCCGCCCGCCCGCTTCGCCTTCGCTCCGCCCAAGGGCGTGGACGTGGTCAGCGGCGACTGA

Upstream 100 bases:

>100_bases
CGCCAACACATTCGCCGGCCCGGCGATGAACCGGGCCGGCGCCGTTCCGGTCCTATCCTTTTTCATTCCGGTCCGCACCG
CCCGCAAGGACATTGACGCC

Downstream 100 bases:

>100_bases
TCTTGTTTTTCGCTTGAAGAAGCCCGCCGCAAACGGCGGGCTTTTTTGCGCCTCAGGCCGGTTTGAGCGCCCAGGTGGCG
ATGAAGGCGGGCAGATAGCG

Product: outer membrane lipoproteins carrier protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKPLFPMLTAAAIAAGLAAPAQASAVAQLKAFVSGSKTLSADFNQTVTNKGKREEASGRLEIARPGKFRWEYTKPYAQLI
VGDGKTLWIYDQDLAQVTRKAQGAALGSSPAALLAGNNEIERSYKLNEAGKQGDLEWLAASPKKQDNTFSAIRMGFKNNV
LVEMQLTDSFGNDTRIVFSQQRQNAALPPARFAFAPPKGVDVVSGD

Sequences:

>Translated_206_residues
MKPLFPMLTAAAIAAGLAAPAQASAVAQLKAFVSGSKTLSADFNQTVTNKGKREEASGRLEIARPGKFRWEYTKPYAQLI
VGDGKTLWIYDQDLAQVTRKAQGAALGSSPAALLAGNNEIERSYKLNEAGKQGDLEWLAASPKKQDNTFSAIRMGFKNNV
LVEMQLTDSFGNDTRIVFSQQRQNAALPPARFAFAPPKGVDVVSGD
>Mature_206_residues
MKPLFPMLTAAAIAAGLAAPAQASAVAQLKAFVSGSKTLSADFNQTVTNKGKREEASGRLEIARPGKFRWEYTKPYAQLI
VGDGKTLWIYDQDLAQVTRKAQGAALGSSPAALLAGNNEIERSYKLNEAGKQGDLEWLAASPKKQDNTFSAIRMGFKNNV
LVEMQLTDSFGNDTRIVFSQQRQNAALPPARFAFAPPKGVDVVSGD

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=199, Percent_Identity=27.6381909547739, Blast_Score=80, Evalue=7e-17,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_CHRVO (Q7NXL2)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_901284.1
- ProteinModelPortal:   Q7NXL2
- SMR:   Q7NXL2
- GeneID:   2550804
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_1614
- NMPDR:   fig|243365.1.peg.1614
- HOGENOM:   HBG688940
- OMA:   MELRDAF
- PhylomeDB:   Q7NXL2
- BioCyc:   CVIO243365:CV_1614-MONOMER
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 22148; Mature: 22148

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLFPMLTAAAIAAGLAAPAQASAVAQLKAFVSGSKTLSADFNQTVTNKGKREEASGRL
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCCHHHHCCCCCCCCCCEE
EIARPGKFRWEYTKPYAQLIVGDGKTLWIYDQDLAQVTRKAQGAALGSSPAALLAGNNEI
EEECCCCEEEEECCCEEEEEECCCCEEEEECHHHHHHHHHHCCCCCCCCCEEEEECCCHH
ERSYKLNEAGKQGDLEWLAASPKKQDNTFSAIRMGFKNNVLVEMQLTDSFGNDTRIVFSQ
HHHEECCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCEEEEEEECCCCCCCEEEEEEC
QRQNAALPPARFAFAPPKGVDVVSGD
CCCCCCCCCCCEECCCCCCCEECCCC
>Mature Secondary Structure
MKPLFPMLTAAAIAAGLAAPAQASAVAQLKAFVSGSKTLSADFNQTVTNKGKREEASGRL
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCCHHHHCCCCCCCCCCEE
EIARPGKFRWEYTKPYAQLIVGDGKTLWIYDQDLAQVTRKAQGAALGSSPAALLAGNNEI
EEECCCCEEEEECCCEEEEEECCCCEEEEECHHHHHHHHHHCCCCCCCCCEEEEECCCHH
ERSYKLNEAGKQGDLEWLAASPKKQDNTFSAIRMGFKNNVLVEMQLTDSFGNDTRIVFSQ
HHHEECCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCEEEEEEECCCCCCCEEEEEEC
QRQNAALPPARFAFAPPKGVDVVSGD
CCCCCCCCCCCEECCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782