Click here to switch to the map view.

The map label for this gene is hoxN [H]

Identifier: 34497028

GI number: 34497028

Start: 1689363

End: 1690499

Strand: Reverse

Name: hoxN [H]

Synonym: CV_1573

Alternate gene names: 34497028

Gene position: 1690499-1689363 (Counterclockwise)

Preceding gene: 34497029

Following gene: 34497027

Centisome position: 35.58

GC content: 66.23

Gene sequence:

>1137_bases
GTGTACCGGGGGATACGCACATGCGCCGTCCATGGATACGCGGCGGTCTGTGCCCTCGCTTGCGCGACGAGTATCGTCTC
CGAGGGCACCATGCATCCATCCACCGCGCCGTCCGTCGGCCGCCGACTGGCGCGCCACGCTCCCATACTCGCCGGGCTGA
TCCTGGCCAACCTGCTGGCCTGGGCCTGGGCGTTCGCCGCCTTCGCCGACTATCCGGCCCAGCTCGCCACCGCCTTGCTC
GCCTACCTGTTCGGCCTGCGCCACGCGGTGGACGCCGACCACATCGCCGCCATAGACAACACCGTGCGCAAGATGATGCA
GGAGAAGCGCCAGCCGTCCGCGGTGGGCCTGTTCTTCTCGCTCGGCCACTCGGCGGTGGTGGTGTTCGCCGTCGCCGTCA
TCGTCATGGCCGCCTCCGCGCTGCAGAGCCGCATCGACGGCTTCCGCGAAATCGGCGGCACCATCAGCGTCAGCGTATCG
GCCTTTTTCCTGCTGGCGCTGGCCATGATCAACCTGTCCTCGCTGCGCGCGGTATGGTCCGCCTTTCGCCGCGCCCGCGC
CGGCGAGCCCATCTGCGACGAACAGCTGGACCTGCTGCTGAACAACCAGGGCCTGCTGGCGCGCCTGCTGCGGCCGCTGT
TCAAGATGGTGACCAAGAGCTGGCACATGCTGCCGATCGGCTTTTTGTTCGGCCTGGGCTTCGACACCGCCACCGAGATC
GGCCTGTTCGCCATCGCCACCACGCAAAGCGCGCACGGCGTGGCGCTGTGGCACATCATGGTGTTCCCGGTGCTGTTCGC
CGCCGGCATGGCGCTGGTGGACACGCTGGACAGCCTGCTGATGGTTGAGGTGTACGGCTGGGCCTTCGTCAAGCCGGTGC
GCAAGCTGTGGTACAACCTGACCATCACCTTCGTCTCCGTCGTCGTCGCGGTGGGCATAGGCGGGCTGGAAGCGCTGGGC
TTGCTGGTGAACAAGATGCGGCTGTCCGGCGGCGCATGGGATCTGGTGGCGGAACTGAACGAAAACCTGGCCCACTTCGG
CTACTTCGTGGTCGGCGTGTTCCTGCTCACTTGGCTCGCCTCCGCCGCCATCTACAAATGGAAGCGTTTCGATCAATTGG
CCCCGGAGATTCAATGA

Upstream 100 bases:

>100_bases
ACTGGCCCTTAGCAAGGTCGGGAAGGCGGCGCCCGGACGGCGACGCGCGAGCCAGGAGACCGGCCGTCAAACGTGTCGAC
GCAAGCAGAAGCCGGGCGGG

Downstream 100 bases:

>100_bases
GAACGCACGACAAACACGTGCTGATGTGCACCGGCCCGCGCTGCACGCCGGGCGGCGAGGGCTCGGAAGCGATGTTCCTG
CACCTGGGACGCGCCATAGA

Product: high affinity nickel transporter transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MYRGIRTCAVHGYAAVCALACATSIVSEGTMHPSTAPSVGRRLARHAPILAGLILANLLAWAWAFAAFADYPAQLATALL
AYLFGLRHAVDADHIAAIDNTVRKMMQEKRQPSAVGLFFSLGHSAVVVFAVAVIVMAASALQSRIDGFREIGGTISVSVS
AFFLLALAMINLSSLRAVWSAFRRARAGEPICDEQLDLLLNNQGLLARLLRPLFKMVTKSWHMLPIGFLFGLGFDTATEI
GLFAIATTQSAHGVALWHIMVFPVLFAAGMALVDTLDSLLMVEVYGWAFVKPVRKLWYNLTITFVSVVVAVGIGGLEALG
LLVNKMRLSGGAWDLVAELNENLAHFGYFVVGVFLLTWLASAAIYKWKRFDQLAPEIQ

Sequences:

>Translated_378_residues
MYRGIRTCAVHGYAAVCALACATSIVSEGTMHPSTAPSVGRRLARHAPILAGLILANLLAWAWAFAAFADYPAQLATALL
AYLFGLRHAVDADHIAAIDNTVRKMMQEKRQPSAVGLFFSLGHSAVVVFAVAVIVMAASALQSRIDGFREIGGTISVSVS
AFFLLALAMINLSSLRAVWSAFRRARAGEPICDEQLDLLLNNQGLLARLLRPLFKMVTKSWHMLPIGFLFGLGFDTATEI
GLFAIATTQSAHGVALWHIMVFPVLFAAGMALVDTLDSLLMVEVYGWAFVKPVRKLWYNLTITFVSVVVAVGIGGLEALG
LLVNKMRLSGGAWDLVAELNENLAHFGYFVVGVFLLTWLASAAIYKWKRFDQLAPEIQ
>Mature_378_residues
MYRGIRTCAVHGYAAVCALACATSIVSEGTMHPSTAPSVGRRLARHAPILAGLILANLLAWAWAFAAFADYPAQLATALL
AYLFGLRHAVDADHIAAIDNTVRKMMQEKRQPSAVGLFFSLGHSAVVVFAVAVIVMAASALQSRIDGFREIGGTISVSVS
AFFLLALAMINLSSLRAVWSAFRRARAGEPICDEQLDLLLNNQGLLARLLRPLFKMVTKSWHMLPIGFLFGLGFDTATEI
GLFAIATTQSAHGVALWHIMVFPVLFAAGMALVDTLDSLLMVEVYGWAFVKPVRKLWYNLTITFVSVVVAVGIGGLEALG
LLVNKMRLSGGAWDLVAELNENLAHFGYFVVGVFLLTWLASAAIYKWKRFDQLAPEIQ

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 40997; Mature: 40997

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRGIRTCAVHGYAAVCALACATSIVSEGTMHPSTAPSVGRRLARHAPILAGLILANLLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WAWAFAAFADYPAQLATALLAYLFGLRHAVDADHIAAIDNTVRKMMQEKRQPSAVGLFFS
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LGHSAVVVFAVAVIVMAASALQSRIDGFREIGGTISVSVSAFFLLALAMINLSSLRAVWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AFRRARAGEPICDEQLDLLLNNQGLLARLLRPLFKMVTKSWHMLPIGFLFGLGFDTATEI
HHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHH
GLFAIATTQSAHGVALWHIMVFPVLFAAGMALVDTLDSLLMVEVYGWAFVKPVRKLWYNL
HHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TITFVSVVVAVGIGGLEALGLLVNKMRLSGGAWDLVAELNENLAHFGYFVVGVFLLTWLA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAAIYKWKRFDQLAPEIQ
HHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYRGIRTCAVHGYAAVCALACATSIVSEGTMHPSTAPSVGRRLARHAPILAGLILANLLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WAWAFAAFADYPAQLATALLAYLFGLRHAVDADHIAAIDNTVRKMMQEKRQPSAVGLFFS
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LGHSAVVVFAVAVIVMAASALQSRIDGFREIGGTISVSVSAFFLLALAMINLSSLRAVWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AFRRARAGEPICDEQLDLLLNNQGLLARLLRPLFKMVTKSWHMLPIGFLFGLGFDTATEI
HHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHH
GLFAIATTQSAHGVALWHIMVFPVLFAAGMALVDTLDSLLMVEVYGWAFVKPVRKLWYNL
HHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TITFVSVVVAVGIGGLEALGLLVNKMRLSGGAWDLVAELNENLAHFGYFVVGVFLLTWLA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAAIYKWKRFDQLAPEIQ
HHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]