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The map label for this gene is cbiL [H]

Identifier: 34497020

GI number: 34497020

Start: 1677998

End: 1678726

Strand: Reverse

Name: cbiL [H]

Synonym: CV_1565

Alternate gene names: 34497020

Gene position: 1678726-1677998 (Counterclockwise)

Preceding gene: 34497021

Following gene: 34497019

Centisome position: 35.33

GC content: 65.84

Gene sequence:

>729_bases
ATGAAGCTGGGACGATTGATAGGCATAGGCGTCGGCCCCGGCCCGGCCGGCTTGATTCCGGTGGCGGCGCTGGCCGCGCT
ACACGAGGCCGACATCGTCTACCTGCCGCGCGCTACCTCCAGCGACACGTCGGTCGCCCGACTATGCCTGGCCGGGCTGG
AGCTGGACGAAAGCCGCTTCCGCGAGATCGAGTTTGAAATGAATCCGGACCGCGGCGCGCTGTCGCGCCATTACGGCGCG
CTGGCCGAGCGGCTGGCCGCCGAATTGAAAACCGGCCGCAACGTCGCCTACCTGACCATAGGCGACTCGATGACTTATTC
GACTTACGGCTACCTGCTGGCGGCGCTGCGCGAAATGCTGCCAGAACTAGAGACGCAGACCTTCCCCGGCGTCACCAGCT
TCGCCGCCACCGCGTCGGCGCTGTCCTGGCCGCTGGGCGAAGGCAAGGAACGCATGCTGATCCTACCCTGCCCCGACGAT
ATGGCCGAGCTGAGGGCGGATATCGAAAGCCACGACATCGTGGTGCTGATGAAGATAGGCAAGCGGCTGCCCGAGGTGCT
GGCGCTGCTGAACCAGATGGGCATCGCCCAGCTGTGCGCCTTCGCCCGCCGCATCGGCCTGCCCGGCGAAGTGCTGTGCG
CCGACGTCTCGCAATTGGACGCCGACGCCAGCGGCTACCTCGCCACCATGCTGATCCGCAAGACAGCCAGAGAAAGACGC
CACTCATGA

Upstream 100 bases:

>100_bases
AACGCCGCACCGCCGCGCGGATGGCCACCAAGGTGCCCAGCGTGCGGCAGGTGGCGGTGCGGCTGTTCAGCATGGACGGC
ACCCCGCTGGGAGAGGCCGC

Downstream 100 bases:

>100_bases
AAGTGTATTTCATCGGCGCCGGCCCCGGCGCCGCCGACCTGATCACGCTGCGCGGCAGCCGCCTGCTAGGCGCCGCCCCG
ATGGTGCTGTACGCCGGCTC

Product: precorrin-2 C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKLGRLIGIGVGPGPAGLIPVAALAALHEADIVYLPRATSSDTSVARLCLAGLELDESRFREIEFEMNPDRGALSRHYGA
LAERLAAELKTGRNVAYLTIGDSMTYSTYGYLLAALREMLPELETQTFPGVTSFAATASALSWPLGEGKERMLILPCPDD
MAELRADIESHDIVVLMKIGKRLPEVLALLNQMGIAQLCAFARRIGLPGEVLCADVSQLDADASGYLATMLIRKTARERR
HS

Sequences:

>Translated_242_residues
MKLGRLIGIGVGPGPAGLIPVAALAALHEADIVYLPRATSSDTSVARLCLAGLELDESRFREIEFEMNPDRGALSRHYGA
LAERLAAELKTGRNVAYLTIGDSMTYSTYGYLLAALREMLPELETQTFPGVTSFAATASALSWPLGEGKERMLILPCPDD
MAELRADIESHDIVVLMKIGKRLPEVLALLNQMGIAQLCAFARRIGLPGEVLCADVSQLDADASGYLATMLIRKTARERR
HS
>Mature_242_residues
MKLGRLIGIGVGPGPAGLIPVAALAALHEADIVYLPRATSSDTSVARLCLAGLELDESRFREIEFEMNPDRGALSRHYGA
LAERLAAELKTGRNVAYLTIGDSMTYSTYGYLLAALREMLPELETQTFPGVTSFAATASALSWPLGEGKERMLILPCPDD
MAELRADIESHDIVVLMKIGKRLPEVLALLNQMGIAQLCAFARRIGLPGEVLCADVSQLDADASGYLATMLIRKTARERR
HS

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 26170; Mature: 26170

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGRLIGIGVGPGPAGLIPVAALAALHEADIVYLPRATSSDTSVARLCLAGLELDESRF
CCCCCEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCCCHHHH
REIEFEMNPDRGALSRHYGALAERLAAELKTGRNVAYLTIGDSMTYSTYGYLLAALREML
HEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
PELETQTFPGVTSFAATASALSWPLGEGKERMLILPCPDDMAELRADIESHDIVVLMKIG
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHCCCCCCEEEHHHHH
KRLPEVLALLNQMGIAQLCAFARRIGLPGEVLCADVSQLDADASGYLATMLIRKTARERR
HHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
HS
CC
>Mature Secondary Structure
MKLGRLIGIGVGPGPAGLIPVAALAALHEADIVYLPRATSSDTSVARLCLAGLELDESRF
CCCCCEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCCCHHHH
REIEFEMNPDRGALSRHYGALAERLAAELKTGRNVAYLTIGDSMTYSTYGYLLAALREML
HEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
PELETQTFPGVTSFAATASALSWPLGEGKERMLILPCPDDMAELRADIESHDIVVLMKIG
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHCCCCCCEEEHHHHH
KRLPEVLALLNQMGIAQLCAFARRIGLPGEVLCADVSQLDADASGYLATMLIRKTARERR
HHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
HS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]