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The map label for this gene is btuC [C]

Identifier: 34497013

GI number: 34497013

Start: 1670508

End: 1671506

Strand: Reverse

Name: btuC [C]

Synonym: CV_1558

Alternate gene names: 34497013

Gene position: 1671506-1670508 (Counterclockwise)

Preceding gene: 34497014

Following gene: 34497012

Centisome position: 35.18

GC content: 74.77

Gene sequence:

>999_bases
CTGACGGCCTGGCCGCTGCAGGGCCTCTTGCTGGCCCTGCTGGCGCTGTCGCTGCCGCTGGCCTCCGGCCTGGGCGCCGC
GCCGGTGGCCTTCTCCGTCAGCTCCAACGTGCTGCTGCACCAGCTGGGCCTGCCGGTGGAGCCGGCTTGGCAGCCGGGCC
AGGACCTGATCATCTGGCAGCTGCGGCTGCCGCGCGTGCTGCTGGGCGGCACGGTCGGCGCCGGCCTGGCGCTGGTCGGC
GCGGCGCTGCAGGCCACCACCCGCAACCAGCTGGCCGACCCGCACCTGCTGGGCGTCAGCTCCGGCGCCACGCTGGGCGC
GGTGACGGTGCTGCTGTTCAGCGGCAATGTGCTGGGCGGCGCCACGCTGCCGCTGGCCGCCTTCACCGGCGCCTTGCTGG
CCACGTTGCTGGTCACCGGCATCGCCGTGCGCCAGCGCCGGCTGCAGGCCGAACGGCTGCTGCTGGCCGGCGTGGCCGTG
TCTTTCCTGCTGATGGCGCTGGCCAATCTGATGCTCTACCTGGGCGACCACCGCTCGGCCTCGGCGGTGCTGTTCTGGAT
GCTGGGCGGCCTGGGCCAGGCGCGCTGGGAGCTGCTGCCGGCGCCGCTGGCCGCGCTGTGCCTGGGCCTCGTCGCGCTGC
TGGCGGTGGCGCGCCCGCTGAACGCGCTGATGGCCGGCGAGCAGACCGCGGTCACGCTGGGCATACGCGTGACCCGGCTG
CGGCTGGCGGTGTTCGCCGCCTCCTCGCTGCTGACCGGCACCATGGTGGCGGTCAGCGGCGCGATCGGCTTCGTCGGCCT
GATGATTCCGCACATCGCCCGCCGCTGCGTCGGCGCCGACCACCGCCGCCTGCTGCCGGCCTGCGCGCTGTTGGGTGCGC
TGTTCCTGATCTGGGTGGACGCCGCCGCGCGCACGCTGATCGCGCCGGAAGACATCCCGGTCGGCGTCGGCACCGCCGCC
GTCGGCGGCGCCTTCTTCATCTGGCTGCTGCGCCGCTGA

Upstream 100 bases:

>100_bases
GCGCGACGCCCGGCATCGCCAATGCCGACGCGATCGGCGCGCTGGCGCGCGGCCTGCACCCGGAGGCCTTCTCCAAGTGA
TCCGCGCCGCCGCCAACCGC

Downstream 100 bases:

>100_bases
CGGCGCGCGCCCCACACGCAAGGACGACACAATGAAAACCGATCCGGCCTCCCACCAGCGCATGACCGAGAAACGCAAGG
CGGGCTTCGAGAAGAAAAAG

Product: vitamin B12 transport system permease

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTAWPLQGLLLALLALSLPLASGLGAAPVAFSVSSNVLLHQLGLPVEPAWQPGQDLIIWQLRLPRVLLGGTVGAGLALVG
AALQATTRNQLADPHLLGVSSGATLGAVTVLLFSGNVLGGATLPLAAFTGALLATLLVTGIAVRQRRLQAERLLLAGVAV
SFLLMALANLMLYLGDHRSASAVLFWMLGGLGQARWELLPAPLAALCLGLVALLAVARPLNALMAGEQTAVTLGIRVTRL
RLAVFAASSLLTGTMVAVSGAIGFVGLMIPHIARRCVGADHRRLLPACALLGALFLIWVDAAARTLIAPEDIPVGVGTAA
VGGAFFIWLLRR

Sequences:

>Translated_332_residues
MTAWPLQGLLLALLALSLPLASGLGAAPVAFSVSSNVLLHQLGLPVEPAWQPGQDLIIWQLRLPRVLLGGTVGAGLALVG
AALQATTRNQLADPHLLGVSSGATLGAVTVLLFSGNVLGGATLPLAAFTGALLATLLVTGIAVRQRRLQAERLLLAGVAV
SFLLMALANLMLYLGDHRSASAVLFWMLGGLGQARWELLPAPLAALCLGLVALLAVARPLNALMAGEQTAVTLGIRVTRL
RLAVFAASSLLTGTMVAVSGAIGFVGLMIPHIARRCVGADHRRLLPACALLGALFLIWVDAAARTLIAPEDIPVGVGTAA
VGGAFFIWLLRR
>Mature_331_residues
TAWPLQGLLLALLALSLPLASGLGAAPVAFSVSSNVLLHQLGLPVEPAWQPGQDLIIWQLRLPRVLLGGTVGAGLALVGA
ALQATTRNQLADPHLLGVSSGATLGAVTVLLFSGNVLGGATLPLAAFTGALLATLLVTGIAVRQRRLQAERLLLAGVAVS
FLLMALANLMLYLGDHRSASAVLFWMLGGLGQARWELLPAPLAALCLGLVALLAVARPLNALMAGEQTAVTLGIRVTRLR
LAVFAASSLLTGTMVAVSGAIGFVGLMIPHIARRCVGADHRRLLPACALLGALFLIWVDAAARTLIAPEDIPVGVGTAAV
GGAFFIWLLRR

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=288, Percent_Identity=41.3194444444444, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790741, Length=280, Percent_Identity=37.5, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1790740, Length=285, Percent_Identity=37.1929824561403, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786805, Length=283, Percent_Identity=37.1024734982332, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1786347, Length=287, Percent_Identity=35.5400696864112, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786804, Length=275, Percent_Identity=33.4545454545455, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34217; Mature: 34085

Theoretical pI: Translated: 11.90; Mature: 11.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAWPLQGLLLALLALSLPLASGLGAAPVAFSVSSNVLLHQLGLPVEPAWQPGQDLIIWQ
CCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHCCCCCCCCCCCCCCEEEEE
LRLPRVLLGGTVGAGLALVGAALQATTRNQLADPHLLGVSSGATLGAVTVLLFSGNVLGG
EECCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCCC
ATLPLAAFTGALLATLLVTGIAVRQRRLQAERLLLAGVAVSFLLMALANLMLYLGDHRSA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SAVLFWMLGGLGQARWELLPAPLAALCLGLVALLAVARPLNALMAGEQTAVTLGIRVTRL
HHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
RLAVFAASSLLTGTMVAVSGAIGFVGLMIPHIARRCVGADHRRLLPACALLGALFLIWVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AAARTLIAPEDIPVGVGTAAVGGAFFIWLLRR
HHHHHEECCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAWPLQGLLLALLALSLPLASGLGAAPVAFSVSSNVLLHQLGLPVEPAWQPGQDLIIWQ
CCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHCCCCCCCCCCCCCCEEEEE
LRLPRVLLGGTVGAGLALVGAALQATTRNQLADPHLLGVSSGATLGAVTVLLFSGNVLGG
EECCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCCC
ATLPLAAFTGALLATLLVTGIAVRQRRLQAERLLLAGVAVSFLLMALANLMLYLGDHRSA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SAVLFWMLGGLGQARWELLPAPLAALCLGLVALLAVARPLNALMAGEQTAVTLGIRVTRL
HHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
RLAVFAASSLLTGTMVAVSGAIGFVGLMIPHIARRCVGADHRRLLPACALLGALFLIWVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AAARTLIAPEDIPVGVGTAAVGGAFFIWLLRR
HHHHHEECCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]