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The map label for this gene is ydhC [C]

Identifier: 34496965

GI number: 34496965

Start: 1612734

End: 1613858

Strand: Reverse

Name: ydhC [C]

Synonym: CV_1510

Alternate gene names: 34496965

Gene position: 1613858-1612734 (Counterclockwise)

Preceding gene: 34496967

Following gene: 34496964

Centisome position: 33.97

GC content: 71.29

Gene sequence:

>1125_bases
ATGAAAACGACGACCCGTCCGGCCCTGTGGCTGCTGACGGTGCTGATCCTGTTCCCGCAACTGGTGGAAACCATCTACAG
TCCGGCGCTGACCGATATCGCCGCCGCCTTCGGCGTCAGCCAGGCCCGCGCCTCGCAAACCTTGTCGGTCTACTTCCTGG
CCTTCGCCGCAGGCGTGGCGCTATGGGGCTGGCTCAGCGACGCGCTCGGCCGCCGCCCGGCGATGCTGCTGGGGCTGGCA
TGCTATGGCGCGGGCTCCGCGCTGGCGCTGGCCGCCGCCGATTTCGACACCCTGCTGCTGGCGCGGATGATTTCCGCGCT
GGGCGCGGCGGCCGGCTCGGTGGTGGTGCAGACCATGCTGCGCGACAGCTACGATTCGGTCGGTCTGGCGCGCGTGTTCT
CGCTGCTGGGCGCGGCGCTGGCGCTGAGCCCGGTGCTGGGCCTGGTCAGCGGCGGCTGGCTGGCCGGCCATTTCGGCCAT
CGCGGCGTGTTCTCCGCCTTGCTGCTGCTTGCCGCCGCGTTGCTGGCGCTGGCCGCGCTGCGGCTGCCGGAAACCCGCCC
GCTCGGCACGGTCCGCCCCGATATGGCGCGGCTCGCCGGCCGCATGCTGCGCGACGCCGAGCTGCGGCGCAATGCGCTGC
GGGTGGCGCTGTTCAACACCATGCTGTTCAGCTACTACAGCCTGGCGCCCTTTCTGTTCGAGCGCCAGGGCTGGAGCCCC
AGCCAGTTTGGCTGGTCAGGCATGGTGCTGGCCGCGGCCTCGCTACTGGGCAGCCTGCTGAACCGCAGGCTGCTGGGAAG
CGGCTGGCAGCCGGCGCAGCTGGTGCGGGCCGCCTGCCGGCTGGCGCTGGCCTCCAGCCTGGCCGCCTGGCTGCTCGGGG
ATTCGGCATGGATACTGCTGCCGGTGGCCGGCGTGGTGATCGCCTTCGGCATCGCCATTCCCAATGTGCTGAGCCAGGCG
CTGCGCGATTACCGCGAGCAGGCCGGCGCCGCCGGCGCGCTGTTCGGCCTCAGCTACTACCTGCAGCTGGGAGCGATGCT
GGCGCTGGCCGGTTTGGCGCAAAACCTCGGCCTGGTGCTGAGCGCCTGTGCCGCCGCCGCGCTCATGTGCCGATCGCCGA
AGTAG

Upstream 100 bases:

>100_bases
CCACGCGTCCGATTTTCAATAGATAAAGTCCTGATCATTGTAATCAGACAAATCGGCTTTCTCTAGACTGGCGTTCGTCA
AGCAAGAAAGGAAAAAAACA

Downstream 100 bases:

>100_bases
TGCGAGCGCGCCCCGGCTGAAGCGCATGCAAGGCCTGGACGCTGCCGCGTCAAGGACTTAGGGCGGAGAGCCGACACCCT
CTGTGCCCGTTCATCGCGCC

Product: multidrug resistance protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MKTTTRPALWLLTVLILFPQLVETIYSPALTDIAAAFGVSQARASQTLSVYFLAFAAGVALWGWLSDALGRRPAMLLGLA
CYGAGSALALAAADFDTLLLARMISALGAAAGSVVVQTMLRDSYDSVGLARVFSLLGAALALSPVLGLVSGGWLAGHFGH
RGVFSALLLLAAALLALAALRLPETRPLGTVRPDMARLAGRMLRDAELRRNALRVALFNTMLFSYYSLAPFLFERQGWSP
SQFGWSGMVLAAASLLGSLLNRRLLGSGWQPAQLVRAACRLALASSLAAWLLGDSAWILLPVAGVVIAFGIAIPNVLSQA
LRDYREQAGAAGALFGLSYYLQLGAMLALAGLAQNLGLVLSACAAAALMCRSPK

Sequences:

>Translated_374_residues
MKTTTRPALWLLTVLILFPQLVETIYSPALTDIAAAFGVSQARASQTLSVYFLAFAAGVALWGWLSDALGRRPAMLLGLA
CYGAGSALALAAADFDTLLLARMISALGAAAGSVVVQTMLRDSYDSVGLARVFSLLGAALALSPVLGLVSGGWLAGHFGH
RGVFSALLLLAAALLALAALRLPETRPLGTVRPDMARLAGRMLRDAELRRNALRVALFNTMLFSYYSLAPFLFERQGWSP
SQFGWSGMVLAAASLLGSLLNRRLLGSGWQPAQLVRAACRLALASSLAAWLLGDSAWILLPVAGVVIAFGIAIPNVLSQA
LRDYREQAGAAGALFGLSYYLQLGAMLALAGLAQNLGLVLSACAAAALMCRSPK
>Mature_374_residues
MKTTTRPALWLLTVLILFPQLVETIYSPALTDIAAAFGVSQARASQTLSVYFLAFAAGVALWGWLSDALGRRPAMLLGLA
CYGAGSALALAAADFDTLLLARMISALGAAAGSVVVQTMLRDSYDSVGLARVFSLLGAALALSPVLGLVSGGWLAGHFGH
RGVFSALLLLAAALLALAALRLPETRPLGTVRPDMARLAGRMLRDAELRRNALRVALFNTMLFSYYSLAPFLFERQGWSP
SQFGWSGMVLAAASLLGSLLNRRLLGSGWQPAQLVRAACRLALASSLAAWLLGDSAWILLPVAGVVIAFGIAIPNVLSQA
LRDYREQAGAAGALFGLSYYLQLGAMLALAGLAQNLGLVLSACAAAALMCRSPK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=329, Percent_Identity=31.306990881459, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1788509, Length=365, Percent_Identity=26.5753424657534, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1790146, Length=371, Percent_Identity=27.7628032345013, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082312, Length=173, Percent_Identity=30.0578034682081, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 39206; Mature: 39206

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA