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The map label for this gene is lytS [H]

Identifier: 34496874

GI number: 34496874

Start: 1497100

End: 1497915

Strand: Reverse

Name: lytS [H]

Synonym: CV_1419

Alternate gene names: 34496874

Gene position: 1497915-1497100 (Counterclockwise)

Preceding gene: 34496875

Following gene: 34496873

Centisome position: 31.53

GC content: 67.28

Gene sequence:

>816_bases
GTGGCGCGGCTGGGCTGGGGCCGGCTGGCGCTGGCCTCCCTGCTGGCGATGATCCTCGGCGGCATCCTGCAACTGCACAT
GCTGGCATTGACGCTGGTGCTGGTGTCGATCCTGGTGAAGATACTCGCCGGCGGCAAATACCAGGCCGAGCAAGCCGCCG
ACCAGGCCATCGCCCGCAGCGAGGAAGCCGAACAGCAGGCGGAGCTGGAAGCGCTGCAGCGCCAGCTGGCGGAAGCGCGG
ATGGGCGCGCTGCAGGCGCAGATCGAGCCGCACTTCCTGTTCAACACCCTGTCGTCGGTGTGCCAGCTGATGGAGGAGTC
GCCGGTCAAGGCGCTGTCCATGCAAAAGGCGCTGATCCGCTACCTGCGCTCCTCGCTGCCGGAATGGCGCGACTCCCCCG
GCGAAACCAGCCTGAGCCAGCAATTGGAGCTGTCCCGCGCCTATCTGGAAATCATGCAACTGCGGATGGAGGACCGGCTG
CAGGTGAGAATTCTGGTGCCGGAATCCTTGCTGCCCGCGCGCTTCCCGGTGATGATGCTGCAGACGCTGGTGGAGAATGC
CATCAAGCACGGCCTGGAGCCCAAAGCGGAAGGCGGCTCGATCGAGGTCCACGCCAAGGTGCTGGACGGCAAGCTCAGGC
TGGAAGTGCGGGACGACGGCGCCGGTTTTCCGGAGCAGCCCGGCCAGGGCATGGGCCTGGCCAACATCCGCGAACGGCTG
GCCCTGCTGTACGGACAACAGGCGGAGCTGACGCTGGAAGCGCCGGCGTCCGGCGGCACCCGCGCCACCATCGCCCTGCC
CTTCGCCCTGACTTGA

Upstream 100 bases:

>100_bases
GTCAAGCATGGATAATGAAAACCGCTCGGCGATGAGCCAGGACCACGTCGGCATGATTCTGAAAACCGTGGAAAAGTGCT
GGTGGCGCTTCGTAGACAAG

Downstream 100 bases:

>100_bases
GAGAAAACCATGAGCACGCTGACCGCCCTGATCGCCGACGACGAACGCCTGATGCGCGAGCAGCTGCGCGCGGCGCTGGA
ACGGGTTTGGCCGGAGCTGG

Product: transmembrane sensor histidine kinase transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MARLGWGRLALASLLAMILGGILQLHMLALTLVLVSILVKILAGGKYQAEQAADQAIARSEEAEQQAELEALQRQLAEAR
MGALQAQIEPHFLFNTLSSVCQLMEESPVKALSMQKALIRYLRSSLPEWRDSPGETSLSQQLELSRAYLEIMQLRMEDRL
QVRILVPESLLPARFPVMMLQTLVENAIKHGLEPKAEGGSIEVHAKVLDGKLRLEVRDDGAGFPEQPGQGMGLANIRERL
ALLYGQQAELTLEAPASGGTRATIALPFALT

Sequences:

>Translated_271_residues
MARLGWGRLALASLLAMILGGILQLHMLALTLVLVSILVKILAGGKYQAEQAADQAIARSEEAEQQAELEALQRQLAEAR
MGALQAQIEPHFLFNTLSSVCQLMEESPVKALSMQKALIRYLRSSLPEWRDSPGETSLSQQLELSRAYLEIMQLRMEDRL
QVRILVPESLLPARFPVMMLQTLVENAIKHGLEPKAEGGSIEVHAKVLDGKLRLEVRDDGAGFPEQPGQGMGLANIRERL
ALLYGQQAELTLEAPASGGTRATIALPFALT
>Mature_270_residues
ARLGWGRLALASLLAMILGGILQLHMLALTLVLVSILVKILAGGKYQAEQAADQAIARSEEAEQQAELEALQRQLAEARM
GALQAQIEPHFLFNTLSSVCQLMEESPVKALSMQKALIRYLRSSLPEWRDSPGETSLSQQLELSRAYLEIMQLRMEDRLQ
VRILVPESLLPARFPVMMLQTLVENAIKHGLEPKAEGGSIEVHAKVLDGKLRLEVRDDGAGFPEQPGQGMGLANIRERLA
LLYGQQAELTLEAPASGGTRATIALPFALT

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=227, Percent_Identity=30.3964757709251, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788446, Length=195, Percent_Identity=30.2564102564103, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 29680; Mature: 29549

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLGWGRLALASLLAMILGGILQLHMLALTLVLVSILVKILAGGKYQAEQAADQAIARS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EEAEQQAELEALQRQLAEARMGALQAQIEPHFLFNTLSSVCQLMEESPVKALSMQKALIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
YLRSSLPEWRDSPGETSLSQQLELSRAYLEIMQLRMEDRLQVRILVPESLLPARFPVMML
HHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHCCHHHHHHHH
QTLVENAIKHGLEPKAEGGSIEVHAKVLDGKLRLEVRDDGAGFPEQPGQGMGLANIRERL
HHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
ALLYGQQAELTLEAPASGGTRATIALPFALT
HHHHCCCCCEEEECCCCCCCEEEEEECEECC
>Mature Secondary Structure 
ARLGWGRLALASLLAMILGGILQLHMLALTLVLVSILVKILAGGKYQAEQAADQAIARS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EEAEQQAELEALQRQLAEARMGALQAQIEPHFLFNTLSSVCQLMEESPVKALSMQKALIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
YLRSSLPEWRDSPGETSLSQQLELSRAYLEIMQLRMEDRLQVRILVPESLLPARFPVMML
HHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHCCHHHHHHHH
QTLVENAIKHGLEPKAEGGSIEVHAKVLDGKLRLEVRDDGAGFPEQPGQGMGLANIRERL
HHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
ALLYGQQAELTLEAPASGGTRATIALPFALT
HHHHCCCCCEEEECCCCCCCEEEEEECEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]