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The map label for this gene is mtnU [H]

Identifier: 34496778

GI number: 34496778

Start: 1393831

End: 1394619

Strand: Direct

Name: mtnU [H]

Synonym: CV_1323

Alternate gene names: 34496778

Gene position: 1393831-1394619 (Clockwise)

Preceding gene: 34496777

Following gene: 34496779

Centisome position: 29.34

GC content: 70.72

Gene sequence:

>789_bases
TTGGCGCAGCTGCCCGCGCCTGAAGCTCCGTCCCGCCTGCTGCCGCTGCTGCGCCAGCGCTGCGAGGAGGCGGCGGCGGA
TGGCGCGCATCTGCTGCTGTTGCCCGAGATGTGGTCCACCGGCTACGCGCCGGCAAAAATGAGTGCCGCCCACGCCTGGA
GCGACGACGCGCCGGTTTTGGCCGAGGTCGCCCGGCTGGCGGCCGAGCTTGGCTTGGCCATCGGCCTCACTTATCTCGCC
CGCCGCGACGGCGCGCTGCGCAACCGGTTGCGTCTGCACGGCGCAGACGGCTCGATCGTTCTGCAGTACGACAAGGTTCA
CATCTGCGATTTCACCGACGGCACCGAGACCGCGCTGCAAGGCGGCGACGGTTTCGCTTGCGCCGACGTCGCGCTTGGCG
GCGAGACGGTGCGCGTCGGCGCCATGATTTGCTTCGACCGCGAGTTTCCCGAAGCCGGCCGCGCGCTGATGCGGCAGGGC
GCCGAACTGGCGCTGGTCCCGAATGCCTGCCCGATGCGCGAGGATGCGGAGCTGGGCGATGTCCGCTTGCAGCAGCTGCG
CGGACGGGCGCTGGAAAACCGCTTCGCCGTCGCGCTGTGCAATTACCCGGCGCCGCAATACGACGGCGCCAGCTGCCTGG
TCGACGCCCGCGGCCGTTTGCTGGCGGCGGGGGACAGGCGGCCGGGCCTGTTGTTGGCGGAGCTCGACCTTGCCGAGCTG
CGGCGTTGGCGCGCTGAGCAGGACGAGGTGTGGGGCGAAGCCGCCTTGAGGCCGTCTTGCTACCGCTGA

Upstream 100 bases:

>100_bases
TGGAGCTGGTGAAGGAAGGCATGGTCAAGGTCAGCCAGGACGCGCCGTACCAGCCCATCTACGTGCGGATCGCGCTGGTG
TGAGCAGGATCCGCCTGGCC

Downstream 100 bases:

>100_bases
ACGCGAAAATGTTATTGTCATCGCCGTGCTATCATCGATGGTCGATCAATCGGACAAGGAGCGGACGCGATGGCGCAGCA
TCAGGCGGAAGTGATCTGGC

Product: hydrolase/nitrilase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MAQLPAPEAPSRLLPLLRQRCEEAAADGAHLLLLPEMWSTGYAPAKMSAAHAWSDDAPVLAEVARLAAELGLAIGLTYLA
RRDGALRNRLRLHGADGSIVLQYDKVHICDFTDGTETALQGGDGFACADVALGGETVRVGAMICFDREFPEAGRALMRQG
AELALVPNACPMREDAELGDVRLQQLRGRALENRFAVALCNYPAPQYDGASCLVDARGRLLAAGDRRPGLLLAELDLAEL
RRWRAEQDEVWGEAALRPSCYR

Sequences:

>Translated_262_residues
MAQLPAPEAPSRLLPLLRQRCEEAAADGAHLLLLPEMWSTGYAPAKMSAAHAWSDDAPVLAEVARLAAELGLAIGLTYLA
RRDGALRNRLRLHGADGSIVLQYDKVHICDFTDGTETALQGGDGFACADVALGGETVRVGAMICFDREFPEAGRALMRQG
AELALVPNACPMREDAELGDVRLQQLRGRALENRFAVALCNYPAPQYDGASCLVDARGRLLAAGDRRPGLLLAELDLAEL
RRWRAEQDEVWGEAALRPSCYR
>Mature_261_residues
AQLPAPEAPSRLLPLLRQRCEEAAADGAHLLLLPEMWSTGYAPAKMSAAHAWSDDAPVLAEVARLAAELGLAIGLTYLAR
RDGALRNRLRLHGADGSIVLQYDKVHICDFTDGTETALQGGDGFACADVALGGETVRVGAMICFDREFPEAGRALMRQGA
ELALVPNACPMREDAELGDVRLQQLRGRALENRFAVALCNYPAPQYDGASCLVDARGRLLAAGDRRPGLLLAELDLAELR
RWRAEQDEVWGEAALRPSCYR

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=240, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 28389; Mature: 28258

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLPAPEAPSRLLPLLRQRCEEAAADGAHLLLLPEMWSTGYAPAKMSAAHAWSDDAPVL
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCCCCCCCHHHCCCCCCHHH
AEVARLAAELGLAIGLTYLARRDGALRNRLRLHGADGSIVLQYDKVHICDFTDGTETALQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHHCEEEECCCCCEEEEECCEEEEECCCCCHHHHC
GGDGFACADVALGGETVRVGAMICFDREFPEAGRALMRQGAELALVPNACPMREDAELGD
CCCCEEEEEEEECCCEEEEEEEEEECCCCCHHHHHHHHCCCCEEECCCCCCCCCCCCHHH
VRLQQLRGRALENRFAVALCNYPAPQYDGASCLVDARGRLLAAGDRRPGLLLAELDLAEL
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCEEEECCCCCCEEEEECCHHHH
RRWRAEQDEVWGEAALRPSCYR
HHHCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AQLPAPEAPSRLLPLLRQRCEEAAADGAHLLLLPEMWSTGYAPAKMSAAHAWSDDAPVL
CCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCCCCCCCHHHCCCCCCHHH
AEVARLAAELGLAIGLTYLARRDGALRNRLRLHGADGSIVLQYDKVHICDFTDGTETALQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHHCEEEECCCCCEEEEECCEEEEECCCCCHHHHC
GGDGFACADVALGGETVRVGAMICFDREFPEAGRALMRQGAELALVPNACPMREDAELGD
CCCCEEEEEEEECCCEEEEEEEEEECCCCCHHHHHHHHCCCCEEECCCCCCCCCCCCHHH
VRLQQLRGRALENRFAVALCNYPAPQYDGASCLVDARGRLLAAGDRRPGLLLAELDLAEL
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCEEEECCCCCCEEEEECCHHHH
RRWRAEQDEVWGEAALRPSCYR
HHHCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]