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The map label for this gene is 34496748

Identifier: 34496748

GI number: 34496748

Start: 1360178

End: 1361062

Strand: Reverse

Name: 34496748

Synonym: CV_1293

Alternate gene names: NA

Gene position: 1361062-1360178 (Counterclockwise)

Preceding gene: 34496753

Following gene: 34496737

Centisome position: 28.65

GC content: 64.97

Gene sequence:

>885_bases
ATGCCAGGCATGACCCCTTCCTCCAGCCAGTATCTGACGCTCAACCGGCGCCGCCATCACCTGCGCCGATGGGGCCCCGA
GCACGCGCCGCTTCTGATATTGCTTCATGGCTGGATGGATAGCTCAGCCACCTTTCAATTCATGGTGGACGCGCTCTCCA
GCGAATGGCAGGTGGTGGCGCCGGACTGGCGCGGTTTCGGCGACAGCCAGTGGAACGATGGCAGTTACTATTTTCCCGAT
TACCTCGCCGATCTGGACGACTTGCTGCGCCAGCTGTCGCCCGGGCGTCCGGTGAATCTGCTGGGCCACAGCATGGGCGC
GATGATCGCCGGCATCTACGCCGGCGTCTGTCCGCAGAGGATAGAAAAGCTGGTGCTGGCGGAAGGTTTCGGCCTCAATC
CGACCCGACCGTCCGAGGCCCCCGGCCGCTATGGCCGTTGGCTGAGGGAAACCAGCCAATCCATCGGCTTCGAGCCGATG
GCAAGCCTGGAACAGGCGGCGAACAAGCTGGTCGCGCGCAACCCGATGCTGACGCCCGAACGGGCACGCTGGCTGGCCGC
CGAGCTGACCCGCCCTGTCGATGGCGGCTTCGTCTACCGCGCCGATCCCCGCCACAAGATGGTCAATCCGGTCTTGTACC
GGCTGGAGGAAGCGATGGCCTGCTGGCGCCGCATCACCGCGCCGGTGCTATGGCTGCTGGGCGAGCACCCGTTCGACCAC
CCCATCGTCAACGACGTGCTGGCCACGCTGGACCAGCGCCGCGCCTGCTTCTCCCGTCTCAGCGAGGCGACGGTGGCCGG
CGCCGGACACATGCTGCAATGGGAGCAGCCAGAAAGCATGGCAGCCATGCTGGAATCATTCCTGCTGGACGATGAAACAC
CATAA

Upstream 100 bases:

>100_bases
ATCTTCATTTCAAGCGGCTTGAGATTGGCTCCGTGCCGATCCGCCTCACTACCCGCCAGGCCGGCATGCGTTTACACTGG
GCGGCTCCACCTCATCGGGA

Downstream 100 bases:

>100_bases
TCGTCTGATTTCATTGACAATCCAAAGCGCCATGACATGGCCTGCCGCTAGTCTGCCACGGCGCCCACCACGACAGGCCA
CAGCCATGGCCATCGAACTG

Product: hydrolase

Products: NA

Alternate protein names: Atropine acylhydrolase; Atropinesterase [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MPGMTPSSSQYLTLNRRRHHLRRWGPEHAPLLILLHGWMDSSATFQFMVDALSSEWQVVAPDWRGFGDSQWNDGSYYFPD
YLADLDDLLRQLSPGRPVNLLGHSMGAMIAGIYAGVCPQRIEKLVLAEGFGLNPTRPSEAPGRYGRWLRETSQSIGFEPM
ASLEQAANKLVARNPMLTPERARWLAAELTRPVDGGFVYRADPRHKMVNPVLYRLEEAMACWRRITAPVLWLLGEHPFDH
PIVNDVLATLDQRRACFSRLSEATVAGAGHMLQWEQPESMAAMLESFLLDDETP

Sequences:

>Translated_294_residues
MPGMTPSSSQYLTLNRRRHHLRRWGPEHAPLLILLHGWMDSSATFQFMVDALSSEWQVVAPDWRGFGDSQWNDGSYYFPD
YLADLDDLLRQLSPGRPVNLLGHSMGAMIAGIYAGVCPQRIEKLVLAEGFGLNPTRPSEAPGRYGRWLRETSQSIGFEPM
ASLEQAANKLVARNPMLTPERARWLAAELTRPVDGGFVYRADPRHKMVNPVLYRLEEAMACWRRITAPVLWLLGEHPFDH
PIVNDVLATLDQRRACFSRLSEATVAGAGHMLQWEQPESMAAMLESFLLDDETP
>Mature_293_residues
PGMTPSSSQYLTLNRRRHHLRRWGPEHAPLLILLHGWMDSSATFQFMVDALSSEWQVVAPDWRGFGDSQWNDGSYYFPDY
LADLDDLLRQLSPGRPVNLLGHSMGAMIAGIYAGVCPQRIEKLVLAEGFGLNPTRPSEAPGRYGRWLRETSQSIGFEPMA
SLEQAANKLVARNPMLTPERARWLAAELTRPVDGGFVYRADPRHKMVNPVLYRLEEAMACWRRITAPVLWLLGEHPFDHP
IVNDVLATLDQRRACFSRLSEATVAGAGHMLQWEQPESMAAMLESFLLDDETP

Specific function: Alkaloid degradation [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Homo sapiens, GI18777795, Length=281, Percent_Identity=23.8434163701068, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17137390, Length=281, Percent_Identity=27.7580071174377, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.10 [H]

Molecular weight: Translated: 33225; Mature: 33094

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGMTPSSSQYLTLNRRRHHLRRWGPEHAPLLILLHGWMDSSATFQFMVDALSSEWQVVA
CCCCCCCCCCEEEHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEC
PDWRGFGDSQWNDGSYYFPDYLADLDDLLRQLSPGRPVNLLGHSMGAMIAGIYAGVCPQR
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHH
IEKLVLAEGFGLNPTRPSEAPGRYGRWLRETSQSIGFEPMASLEQAANKLVARNPMLTPE
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHH
RARWLAAELTRPVDGGFVYRADPRHKMVNPVLYRLEEAMACWRRITAPVLWLLGEHPFDH
HHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PIVNDVLATLDQRRACFSRLSEATVAGAGHMLQWEQPESMAAMLESFLLDDETP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PGMTPSSSQYLTLNRRRHHLRRWGPEHAPLLILLHGWMDSSATFQFMVDALSSEWQVVA
CCCCCCCCCEEEHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEC
PDWRGFGDSQWNDGSYYFPDYLADLDDLLRQLSPGRPVNLLGHSMGAMIAGIYAGVCPQR
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHH
IEKLVLAEGFGLNPTRPSEAPGRYGRWLRETSQSIGFEPMASLEQAANKLVARNPMLTPE
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHH
RARWLAAELTRPVDGGFVYRADPRHKMVNPVLYRLEEAMACWRRITAPVLWLLGEHPFDH
HHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PIVNDVLATLDQRRACFSRLSEATVAGAGHMLQWEQPESMAAMLESFLLDDETP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA