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The map label for this gene is rcsC [H]

Identifier: 34496565

GI number: 34496565

Start: 1160562

End: 1162355

Strand: Reverse

Name: rcsC [H]

Synonym: CV_1110

Alternate gene names: 34496565

Gene position: 1162355-1160562 (Counterclockwise)

Preceding gene: 34496566

Following gene: 34496550

Centisome position: 24.47

GC content: 62.37

Gene sequence:

>1794_bases
ATGCGCGCAGCCGTCAATGTGGAAACCCGCAGCTTGGCCGTCGGCCATGATTACGCCGAGAAATGGCAGGAGGTGCTGGA
TTTGCTGGCCAAGCTGGTCCGCATCCCGGCCGCGCTGATCATGCGGGCGCAGCCGCCGCAGATCAAGGTCTTCTTGTCTA
GCCGCAGCAAAGGCAACCCCTACGAGGAAGACGAGCTCGCCGATCTGGGCACCGGGCTCTACTGCGAAACCGTCATGGCC
CGCCGCGGCGAACTCATCGTTCCCAACGCGCTGACGGATCCCGCCTGGGACCACAATCCGGACATCAAGCTGGGCATGAT
CTCCTACATGGGGATGCCCCTGGTCTGGCCCAACCAGGACGTGTTCGGCACCATTTGCGTGCTCGATGTCGAAGAAAACG
CCTACAACGCCACCTACCGGCAGCTGCTGGCGCAATTCCGCGCCATGGTCGAGCGCGATCTCAGGCAGATCTACAACGAC
AAGGCCCGCGCCCAAGAGGATGCCGCGCTGCGCGCCGAAGAAGCGGAGCGGGTCCGCCGCGAGTTCGAACTGCTGAGGGC
CGGCGAGCAAAAAGCGCTGCAGGCGCTGCGCGAGAGCGAAGAACGCTGGCACTTCGCGCTCGAAGGCGCAGGCGACGGCG
TCTGGGACTGGGACATCTCCAACGGGAGCATCTTCTTTTCCAGCCGCTGCCGGCAGTTGTTGGGCCTGACCGCTCCGGAG
GCAATCGCCGGCTTCCAGCTGTGGCAGACCGGCATCCACCCGGATGAGCGCCCCACCGTGCAGGCCGAGCTGGCCGGCTA
CCTGCGGCAACCCGAGGGCTCCTTTGTCACCGAGCACCGTTTCCGCAAGGGAGAAGAATGGATCTGGCTGCTGGGACGCG
GCATGGTTGTCAGCCTGGACATTCAAGGACGGCCGCTGCGGATGATAGGCACCTACTCCGACATCACCGAACGCAAGGAA
GCCGAGGCGGAGCTGCAGCTTTTGAACAGCCATCTGGAAGAGAGGGTGGCCGCCCGCACAGCCGAGCTGAAAAAAGCGAT
GCAGCAGATCAGCATCGCCGAGAAACAAGCGGCGCTGGCAAGAATGGTCGCAGGCATGGCGCATGAGTTGAATACGCCGA
TAGGCAACATCCTGCTATGTTCGTCGCAGATACAGGCTGACGTGGCAGCCATCGCCAAGGCCGATACCGACCGGCTGCTT
TCTCGCAAAGGCTTGCAGAGTTTTCTGCAGAAGGCGGCAGAGAGCTGCGAGCTCCTGCAACGCAACAGCGAACTGGCTGG
CGACCTGATCGGCCGCTTCAAGCAGATCGCCGTCGATCAGCTCGATCAGCCGCGACGCAGCTTCCATCCGGCACAGATCA
TTTCCAGGCTGCTGCAAACGCTGCTGCCGCCCGAACACCATCCTGATATCGACGTCCAGCTGCGGATTCCGGACCGCTTG
GTCATTGAGAATTACCCCAGCGCGCTGGAGCAACTGCTTTCCCATCTGGTGGCCAACTCGCTGACCCACGGCTTCGAGGA
AAAAGGCGTCGGCTGCATCCGCATCGACATCCGCCGCGATCAGGAAGAACTGATCCTGATCTACTCGGACGATGGAAAAG
GCATCACCCAGGAGCTGCAAAGCAGGGTATTCGACCCATTCTTCACCACCCGAATGGGGCAAGGCGGCGTGGGTTTGGGC
CTGGCCCTGGTCCACAACATCGTCCAGGTCATTCTGAAGGGGCAGATCCGGCTGGAAAGCGAGCCTGGCCAGGGCGCAGC
CTTCATCATCACGTTCCCGGCGAACCAGGGCTGA

Upstream 100 bases:

>100_bases
GCGCCGTCCCGCCCCTTCACCCCATAGCCCCGCTTGCCGGGGCTTTTTGCCGCCCTCGGCTATGATTAAGCGGAGAACCG
GAGTCCCTGTGGAGAGGGCG

Downstream 100 bases:

>100_bases
TTTCGATACCCCCAGCAGAGCGGGACAAGTGGCAGATCGCCATGGCCACTCCATGCCATCGACATGAGTGTGCCTTCTTG
CCGCAGAGTATCGGCTTATG

Product: hypothetical protein

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MRAAVNVETRSLAVGHDYAEKWQEVLDLLAKLVRIPAALIMRAQPPQIKVFLSSRSKGNPYEEDELADLGTGLYCETVMA
RRGELIVPNALTDPAWDHNPDIKLGMISYMGMPLVWPNQDVFGTICVLDVEENAYNATYRQLLAQFRAMVERDLRQIYND
KARAQEDAALRAEEAERVRREFELLRAGEQKALQALRESEERWHFALEGAGDGVWDWDISNGSIFFSSRCRQLLGLTAPE
AIAGFQLWQTGIHPDERPTVQAELAGYLRQPEGSFVTEHRFRKGEEWIWLLGRGMVVSLDIQGRPLRMIGTYSDITERKE
AEAELQLLNSHLEERVAARTAELKKAMQQISIAEKQAALARMVAGMAHELNTPIGNILLCSSQIQADVAAIAKADTDRLL
SRKGLQSFLQKAAESCELLQRNSELAGDLIGRFKQIAVDQLDQPRRSFHPAQIISRLLQTLLPPEHHPDIDVQLRIPDRL
VIENYPSALEQLLSHLVANSLTHGFEEKGVGCIRIDIRRDQEELILIYSDDGKGITQELQSRVFDPFFTTRMGQGGVGLG
LALVHNIVQVILKGQIRLESEPGQGAAFIITFPANQG

Sequences:

>Translated_597_residues
MRAAVNVETRSLAVGHDYAEKWQEVLDLLAKLVRIPAALIMRAQPPQIKVFLSSRSKGNPYEEDELADLGTGLYCETVMA
RRGELIVPNALTDPAWDHNPDIKLGMISYMGMPLVWPNQDVFGTICVLDVEENAYNATYRQLLAQFRAMVERDLRQIYND
KARAQEDAALRAEEAERVRREFELLRAGEQKALQALRESEERWHFALEGAGDGVWDWDISNGSIFFSSRCRQLLGLTAPE
AIAGFQLWQTGIHPDERPTVQAELAGYLRQPEGSFVTEHRFRKGEEWIWLLGRGMVVSLDIQGRPLRMIGTYSDITERKE
AEAELQLLNSHLEERVAARTAELKKAMQQISIAEKQAALARMVAGMAHELNTPIGNILLCSSQIQADVAAIAKADTDRLL
SRKGLQSFLQKAAESCELLQRNSELAGDLIGRFKQIAVDQLDQPRRSFHPAQIISRLLQTLLPPEHHPDIDVQLRIPDRL
VIENYPSALEQLLSHLVANSLTHGFEEKGVGCIRIDIRRDQEELILIYSDDGKGITQELQSRVFDPFFTTRMGQGGVGLG
LALVHNIVQVILKGQIRLESEPGQGAAFIITFPANQG
>Mature_597_residues
MRAAVNVETRSLAVGHDYAEKWQEVLDLLAKLVRIPAALIMRAQPPQIKVFLSSRSKGNPYEEDELADLGTGLYCETVMA
RRGELIVPNALTDPAWDHNPDIKLGMISYMGMPLVWPNQDVFGTICVLDVEENAYNATYRQLLAQFRAMVERDLRQIYND
KARAQEDAALRAEEAERVRREFELLRAGEQKALQALRESEERWHFALEGAGDGVWDWDISNGSIFFSSRCRQLLGLTAPE
AIAGFQLWQTGIHPDERPTVQAELAGYLRQPEGSFVTEHRFRKGEEWIWLLGRGMVVSLDIQGRPLRMIGTYSDITERKE
AEAELQLLNSHLEERVAARTAELKKAMQQISIAEKQAALARMVAGMAHELNTPIGNILLCSSQIQADVAAIAKADTDRLL
SRKGLQSFLQKAAESCELLQRNSELAGDLIGRFKQIAVDQLDQPRRSFHPAQIISRLLQTLLPPEHHPDIDVQLRIPDRL
VIENYPSALEQLLSHLVANSLTHGFEEKGVGCIRIDIRRDQEELILIYSDDGKGITQELQSRVFDPFFTTRMGQGGVGLG
LALVHNIVQVILKGQIRLESEPGQGAAFIITFPANQG

Specific function: Member of the two-component regulatory system RcsC/RcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with RcsF, RcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=271, Percent_Identity=27.3062730627306, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788549, Length=428, Percent_Identity=25.2336448598131, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=26.7489711934156, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87081816, Length=281, Percent_Identity=28.1138790035587, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788713, Length=252, Percent_Identity=25.3968253968254, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66972; Mature: 66972

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAVNVETRSLAVGHDYAEKWQEVLDLLAKLVRIPAALIMRAQPPQIKVFLSSRSKGNP
CCCEEECCHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
YEEDELADLGTGLYCETVMARRGELIVPNALTDPAWDHNPDIKLGMISYMGMPLVWPNQD
CCCHHHHHCCCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEHHHHCCCCEECCCCC
VFGTICVLDVEENAYNATYRQLLAQFRAMVERDLRQIYNDKARAQEDAALRAEEAERVRR
CEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFELLRAGEQKALQALRESEERWHFALEGAGDGVWDWDISNGSIFFSSRCRQLLGLTAPE
HHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCCEEEEECCCCCEEHHHHHHHHHCCCCCH
AIAGFQLWQTGIHPDERPTVQAELAGYLRQPEGSFVTEHRFRKGEEWIWLLGRGMVVSLD
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEECCCEEEEEE
IQGRPLRMIGTYSDITERKEAEAELQLLNSHLEERVAARTAELKKAMQQISIAEKQAALA
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMVAGMAHELNTPIGNILLCSSQIQADVAAIAKADTDRLLSRKGLQSFLQKAAESCELLQ
HHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
RNSELAGDLIGRFKQIAVDQLDQPRRSFHPAQIISRLLQTLLPPEHHPDIDVQLRIPDRL
HCHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCH
VIENYPSALEQLLSHLVANSLTHGFEEKGVGCIRIDIRRDQEELILIYSDDGKGITQELQ
HHHCCHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEEECCCCEEEEEECCCCCCHHHHHH
SRVFDPFFTTRMGQGGVGLGLALVHNIVQVILKGQIRLESEPGQGAAFIITFPANQG
HHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MRAAVNVETRSLAVGHDYAEKWQEVLDLLAKLVRIPAALIMRAQPPQIKVFLSSRSKGNP
CCCEEECCHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
YEEDELADLGTGLYCETVMARRGELIVPNALTDPAWDHNPDIKLGMISYMGMPLVWPNQD
CCCHHHHHCCCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEHHHHCCCCEECCCCC
VFGTICVLDVEENAYNATYRQLLAQFRAMVERDLRQIYNDKARAQEDAALRAEEAERVRR
CEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFELLRAGEQKALQALRESEERWHFALEGAGDGVWDWDISNGSIFFSSRCRQLLGLTAPE
HHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCCEEEEECCCCCEEHHHHHHHHHCCCCCH
AIAGFQLWQTGIHPDERPTVQAELAGYLRQPEGSFVTEHRFRKGEEWIWLLGRGMVVSLD
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEECCCEEEEEE
IQGRPLRMIGTYSDITERKEAEAELQLLNSHLEERVAARTAELKKAMQQISIAEKQAALA
CCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMVAGMAHELNTPIGNILLCSSQIQADVAAIAKADTDRLLSRKGLQSFLQKAAESCELLQ
HHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
RNSELAGDLIGRFKQIAVDQLDQPRRSFHPAQIISRLLQTLLPPEHHPDIDVQLRIPDRL
HCHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCH
VIENYPSALEQLLSHLVANSLTHGFEEKGVGCIRIDIRRDQEELILIYSDDGKGITQELQ
HHHCCHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEEECCCCEEEEEECCCCCCHHHHHH
SRVFDPFFTTRMGQGGVGLGLALVHNIVQVILKGQIRLESEPGQGAAFIITFPANQG
HHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2404948; 8366025; 9097040; 9278503; 11758943; 11309126; 13129944 [H]