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The map label for this gene is hscB [H]

Identifier: 34496546

GI number: 34496546

Start: 1138223

End: 1138768

Strand: Reverse

Name: hscB [H]

Synonym: CV_1091

Alternate gene names: 34496546

Gene position: 1138768-1138223 (Counterclockwise)

Preceding gene: 34496547

Following gene: 34496545

Centisome position: 23.97

GC content: 67.03

Gene sequence:

>546_bases
TTGAGTCCGGACGCATCGATGAACCACGATTTCAACCAGGATTTCTTCAGCCTGTTCGGCCTGCCGCGCCGCTTCGCCAT
CGACGCCGCCGGCCTCGACGCCGCCTGGCGCGCGGCGGCGGCCCAGGTCCATCCCGACCGCTATGCCGCCAGCTCCGACG
CCGACAAGCGCAGCGCGCTGATGCTCGCCACCCGCGTCAACGAGGGCTACCAGACGCTGAAGTCGCCGCTGAACCGCGCC
CGCTACCTGCTGCAGCTGTCCGGCGTCGACACCCAGGAAGAGAACAACACCCGGATGCCGGCCGATTTCCTGATGGCGCA
GATGGAATGGCGCGAGAGCATAGACGACGCCCGCGCCGACGTGGACGCGCTGGAGTCGCTGTCGCGCCGCCTGCGCGGCG
AAGTCAGGGACCTGCAGACCGAACTGGAAGCGGCGCTGGATGCGCGCGCCGACTTGGACGCCGCCGCCGTTCTGGTGAGA
AAATTGCGTTTCATGGAAAAGCTGGACCAGGAGATCGGCGACGCCATCGAAAGCCTGCTGGACTAG

Upstream 100 bases:

>100_bases
GGCTGCGGCGAGAGCTTCAACGTCTGACCGCCGCCGCCCCGGGGCGGAGCGTTGACGCGCAAGCGCTGATGCTCCGCCCT
CGTTTTTTCAGTCCCCACGC

Downstream 100 bases:

>100_bases
CATGCTCGCCGCGGAATATCGGCAAGCCTTGCGGCAGCAAGCCTGGGCATGGATGCCGGGCATCGGCTACCTGCTGTTCC
AGATCCTGATGCTGCTGCCC

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MSPDASMNHDFNQDFFSLFGLPRRFAIDAAGLDAAWRAAAAQVHPDRYAASSDADKRSALMLATRVNEGYQTLKSPLNRA
RYLLQLSGVDTQEENNTRMPADFLMAQMEWRESIDDARADVDALESLSRRLRGEVRDLQTELEAALDARADLDAAAVLVR
KLRFMEKLDQEIGDAIESLLD

Sequences:

>Translated_181_residues
MSPDASMNHDFNQDFFSLFGLPRRFAIDAAGLDAAWRAAAAQVHPDRYAASSDADKRSALMLATRVNEGYQTLKSPLNRA
RYLLQLSGVDTQEENNTRMPADFLMAQMEWRESIDDARADVDALESLSRRLRGEVRDLQTELEAALDARADLDAAAVLVR
KLRFMEKLDQEIGDAIESLLD
>Mature_180_residues
SPDASMNHDFNQDFFSLFGLPRRFAIDAAGLDAAWRAAAAQVHPDRYAASSDADKRSALMLATRVNEGYQTLKSPLNRAR
YLLQLSGVDTQEENNTRMPADFLMAQMEWRESIDDARADVDALESLSRRLRGEVRDLQTELEAALDARADLDAAAVLVRK
LRFMEKLDQEIGDAIESLLD

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=163, Percent_Identity=27.6073619631902, Blast_Score=78, Evalue=5e-15,
Organism=Escherichia coli, GI1788876, Length=170, Percent_Identity=38.2352941176471, Blast_Score=107, Evalue=6e-25,
Organism=Drosophila melanogaster, GI161084223, Length=167, Percent_Identity=28.7425149700599, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 20292; Mature: 20161

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPDASMNHDFNQDFFSLFGLPRRFAIDAAGLDAAWRAAAAQVHPDRYAASSDADKRSAL
CCCCCCCCCCCCHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCHHHCCCCCCHHHHHH
MLATRVNEGYQTLKSPLNRARYLLQLSGVDTQEENNTRMPADFLMAQMEWRESIDDARAD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VDALESLSRRLRGEVRDLQTELEAALDARADLDAAAVLVRKLRFMEKLDQEIGDAIESLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
D
C
>Mature Secondary Structure 
SPDASMNHDFNQDFFSLFGLPRRFAIDAAGLDAAWRAAAAQVHPDRYAASSDADKRSAL
CCCCCCCCCCCHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCHHHCCCCCCHHHHHH
MLATRVNEGYQTLKSPLNRARYLLQLSGVDTQEENNTRMPADFLMAQMEWRESIDDARAD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VDALESLSRRLRGEVRDLQTELEAALDARADLDAAAVLVRKLRFMEKLDQEIGDAIESLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]